Aliases for MT-ND4L Gene
External Ids for MT-ND4L Gene
Previous HGNC Symbols for MT-ND4L Gene
Previous GeneCards Identifiers for MT-ND4L Gene
GeneCards Summary for MT-ND4L Gene
MT-ND4L (Mitochondrially Encoded NADH:Ubiquinone Oxidoreductase Core Subunit 4L) is a Protein Coding gene. Diseases associated with MT-ND4L include leber hereditary optic neuropathy and tubulointerstitial nephritis and uveitis. Among its related pathways are Metabolism and Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.. GO annotations related to this gene include NADH dehydrogenase (ubiquinone) activity and oxidoreductase activity, acting on NAD(P)H.
UniProtKB/Swiss-Prot for MT-ND4L Gene
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).