MT-CO1 Gene
protein-coding GIFtS: 46
GCID: GCMTP005906
|
|
mitochondrially encoded cytochrome c oxidase I(Previous name: cytochrome c oxidase I )
(Previous symbol: MTCO1)
| |
Aliases
for MT-CO1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Mitochondrially Encoded Cytochrome C Oxidase I1 | | Cytochrome C Oxidase I1 | | COI1 2 3 | | Cytochrome C Oxidase Subunit I2 | | MTCO11 2 3 | | COXI3 | | COX11 2 | | Cytochrome C Oxidase Polypeptide I3 | | EC 1.9.3.13 8 | | |
Export aliases for MT-CO1 gene to outside databasesPrevious GC identifers: GC00U921584 GCMTP005585 |
Summaries
for MT-CO1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: COX1_HUMAN, P00395Function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen towater. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme.Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 tothe bimetallic center formed by heme A3 and copper B
Gene Wiki entry for MT-CO1
|
Genomic Views
for MT-CO1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for MT-CO1
Other transcription factors
Search SABiosciences Chromatin IP Primers for MT-CO1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MT-CO1 |
Genomic Location:
Chromosome:MT
Ensembl cytogenetic band: MT HGNC chromosome: mitochondriaGeneLoc information about chromosome MT GeneLoc Exon Structure GeneLoc location for GCMTP005906: view genomic region
(about GC identifiers)
Start:
|
5,904 bp from pter |
End:
|
7,445 bp from pter |
Size:
|
1,542 bases |
Orientation:
|
plus strand |
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Proteins
for MT-CO1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: COX1_HUMAN, P00395 (See
protein sequence)Recommended Name: Cytochrome c oxidase subunit 1 Size: 513 amino acids; 57041 Da
Subcellular location: Mitochondrion inner membrane; Multi-pass membrane protein
Secondary accessions: Q34770Explore the universe of human proteins at neXtProt for MT-CO1: NX_P00395
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P00395
4/47 DME Specific Peptides for MT-CO1 (P00395) (see all 47)
MT-CO1 Protein expression data from MOPED and PaxDb: About this image 
ENSEMBL proteins: ENSP00000354499 Reactome Protein details: P00395
Human Recombinant Protein Products for MT-CO1:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
MT-CO1 for ontologies About GeneDecksing
MT-CO1 Antibody Products:
Assay Products for MT-CO1: |
Protein
Domains /
Families
for MT-CO1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
MT-CO1 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P00395ProtoNet protein and cluster: P00395 1 Blocks protein family: IPB000883 Cytochrome c oxidase
UniProtKB/Swiss-Prot: COX1_HUMAN, P00395Similarity: Belongs to the heme-copper respiratory oxidase family |
Function
for MT-CO1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: COX1_HUMAN, P00395Function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen towater. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme.Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 tothe bimetallic center formed by heme A3 and copper BCatalytic activity: 4 ferrocytochrome c + O(2) + 4 H(+) = 4 ferricytochrome c + 2 H(2)O Enzyme Number (IUBMB): EC 1.9.3.11 2
Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view): About this table
MT-CO1 for ontologies About GeneDecksing
Phenotypes:
6 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for mt-Co1):
MT-CO1 for phenotypes About GeneDecksing
Animal Models:
|
Pathways & Interactions
for MT-CO1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table 
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. | | | 2 | Metabolism | | | 3 | Cardiac muscle contraction | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1  BioSystems Pathway for MT-CO1
4 
Reactome Pathways for MT-CO1
5/6 
Kegg Pathways (Kegg details for MT-CO1) (see all 6):
UniProtKB/Swiss-Prot: COX1_HUMAN, P00395Pathway: Energy metabolism; oxidative phosphorylation
MT-CO1 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MT-CO1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/61 Interacting proteins for MT-CO1 (P003952, 3 ENSP000003544994) via UniProtKB, MINT, STRING, and/or I2D (see all 61)
About this table
Gene Ontology (GO): 5/9 biological process terms (GO ID links to tree view) (see all 9): About this table
MT-CO1 for ontologies About GeneDecksing
|
Drugs & Compounds
for MT-CO1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
MT-CO1 for compounds About GeneDecksing
 Browse Tocris compounds for MT-CO1
5 HMDB Compounds for MT-CO1 About this table
2 DrugBank Compounds for MT-CO1 About this table
10/13 Novoseek chemical compound relationships for MT-CO1 gene (see all 13) About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| solium |
66 |
10 |
11163447 (1), 12781383 (1), 17245015 (1), 7905720 (1) (see all 6) |
| nadh |
62.7 |
31 |
17918379 (2), 9684648 (1), 12615166 (1), 16025565 (1) (see all 24) |
| rrna |
59.3 |
54 |
9603116 (3), 18415704 (2), 15599059 (1), 18372194 (1) (see all 19) |
| ribonucleic acid |
17.8 |
3 |
12721215 (1), 12762840 (1), 15163090 (1) |
| atp |
14.9 |
9 |
12227430 (1), 16210000 (1), 20108082 (1), 18823003 (1) (see all 6) |
| citrate |
12.9 |
3 |
19465554 (1), 20044477 (1), 17130474 (1) |
| glucose |
2.45 |
1 |
17130474 (1) |
| deoxyribonucleic acid |
0.776 |
2 |
17245015 (1), 12762840 (1) |
| oxygen |
0 |
3 |
18493604 (1), 17499267 (1) |
| sodium |
0 |
5 |
17134587 (1), 11756511 (1) |
Search CenterWatch for drugs/clinical trials and news about MT-CO1 / COX1
|
Transcripts
for MT-CO1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
1 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000361624(uc011mfh.2)
GeneLoc Exon Structure
|
Expression
for MT-CO1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| MT-CO1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See MT-CO1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for MT-CO1
SABiosciences Custom PCR Arrays for MT-CO1
Primer
Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MT-CO1
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat MT-CO1 | | | Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MT-CO1 | | | Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MT-CO1 |
Orthologs
for MT-CO1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the last universal common ancestor (LUCA).
Orthologs for MT-CO1 gene from 10/26 species (see all 26) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
mt-Co15
COX11 |
mitochondrially encoded cytochrome c oxidase I5
cytochrome c oxidase subunit I1 |
77.93(n)1
89.65(a)1 |
|
MT5
177081 COX1_345386001 NP_904330.11
53285 |
chicken
(Gallus gallus) |
Aves |
COX11 |
cytochrome c oxidase subunit I |
77.19(n)
83.53(a) |
|
807639 COX1_5834846 NP_006917.1 |
African clawed frog
(Xenopus laevis) |
Amphibia |
BQ884363.12 |
-- |
77.81(n) |
|
BQ884363.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
Dr.20072 |
Transcribed sequence with moderate similarity to protein more |
75.94(n) |
|
AI545762.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
COX11 |
cytochrome c oxidase subunit I |
66.8(n)
75.35(a) |
|
192469 COX1_5835235 NP_008278.1 |
worm
(Caenorhabditis elegans) |
Secernentea |
COX11 |
cytochrome c oxidase subunit I |
57.4(n)
57.99(a) |
|
2565700 COX1_5834891 NP_006961.1 |
baker's yeast
(Saccharomyces cerevisiae) |
Saccharomycetes |
COX1(Q0045)4
COX11 |
Subunit I of cytochrome c oxidase, which is the terminal more4
Cox1p1 |
59.24(n)1
58.65(a)1 |
|
17(13818-26701)4
8545981, 4 NP_009305.11, 4 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
cox11 |
cytochrome c oxidase subunit 1 |
61.62(n)
67.33(a) |
|
814620 cox1_13449404 NP_085587.1 |
rice
(Oryza sativa) |
Liliopsida |
Os.235162 |
Transcribed sequence with weak similarity to protein more |
70.69(n) |
|
CA759861.1 |
E. coli
(Escherichia coli) |
Gamma proteobacteria |
cyoB6 |
cytochrome o ubiquinol oxidase subunit I |
30(a) |
1 ↔ 1 |
Chromosome(447874-449865) b0431 |
ENSEMBL Gene Tree for MT-CO1 (if available)
TreeFam Gene Tree for MT-CO1 (if available) |
Paralogs
for MT-CO1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for MT-CO1 gene
5 SIMAP similar genes for MT-CO1 using alignment to 1 protein entry: COX1_HUMAN:CO1 COI COXI cox1 COX1
MT-CO1 for paralogs About GeneDecksing
5/79 Pseudogenes.org Pseudogenes for MT-CO1 (see all 79)
PGOHUM00000238520 PGOHUM00000242449 PGOHUM00000242644 PGOHUM00000242798 PGOHUM00000239309
|
Genomic Variants
for MT-CO1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
Human Gene Mutation Database (HGMD): MT-CO1
| SABiosciences Cancer Mutation PCR Assays |
|
Disorders
/ Diseases
for MT-CO1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
MT-CO1 for disorders About GeneDecksing
OMIM gene information: 516030
OMIM disorders: --
UniProtKB/Swiss-Prot: COX1_HUMAN, P00395
Defects in MT-CO1 are a cause of Leber hereditary optic neuropathy (LHON) [MIM:535000]. LHON is a maternallyinherited disease resulting in acute or subacute loss of central vision, due to optic nerve dysfunction. Cardiacconduction defects and neurological defects have also been described in some patients. LHON results from primarymitochondrial DNA mutations affecting the respiratory chain complexes Note=MT-CO1 may play a role in the pathogenesis of acquired idiopathic sideroblastic anemia, a diseasecharacterized by inadequate formation of heme and excessive accumulation of iron in mitochondria. Mitochondrial ironoverload may be attributable to mutations of mitochondrial DNA because these can cause respiratory chain dysfunction,thereby impairing reduction of ferric iron to ferrous iron. The reduced form of iron is essential to the last step ofmitochondrial heme biosynthesis Defects in MT-CO1 are a cause of mitochondrial complex IV deficiency (MT-C4D) [MIM:220110]; also known ascytochrome c oxidase deficiency. A disorder of the mitochondrial respiratory chain with heterogeneous clinicalmanifestations, ranging from isolated myopathy to severe multisystem disease affecting several tissues and organs.Features include hypertrophic cardiomyopathy, hepatomegaly and liver dysfunction, hypotonia, muscle weakness,excercise intolerance, developmental delay, delayed motor development and mental retardation. A subset of patientsmanifest Leigh syndrome Defects in MT-CO1 are associated with recurrent myoglobinuria mitochondrial (RM-MT) [MIM:550500]. Recurrentmyoglobinuria is characterized by recurrent attacks of rhabdomyolysis (necrosis or disintegration of skeletal muscle)associated with muscle pain and weakness, and followed by excretion of myoglobin in the urine Defects in MT-CO1 are a cause of deafness sensorineural mitochondrial (DFNM) [MIM:500008]. DFNM is a form ofnon-syndromic deafness with maternal inheritance. Affected individuals manifest progressive, postlingual,sensorineural hearing loss involving high frequencies Defects in MT-CO1 are a cause of colorectal cancer (CRC) [MIM:114500]
20/56  diseases for MT-CO1 (see all 56): About MalaCardsleber hereditary optic neuropathy pthirus pubis infestation leech infestation alveolar echinococcosis
type 2 diabetes mellitus echinococcosis mitochondrial encephalomyopathy iron overload
steatitis lactic acidosis myiasis chronic obstructive pulmonary disease
megaloblastic anemia sideroblastic anemia virilization cystic echinococcosis
diphyllobothriasis encephalomyopathy cysticercosis diabetes mellitus
4 diseases from the University of Copenhagen DISEASES database for MT-CO1:Echinococcosis Pthirus pubis infestation Steatitis Sparganosis 10/15 Novoseek disease relationships for MT-CO1 gene (see all 15) About this table
Genetic Association Database (GAD): MT-CO1
Export disorders for MT-CO1 gene to outside databases
|
Publications
for MT-CO1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for MT-CO1 gene, integrated from 9 sources (see all 252):
(articles sorted by number of sources associating them with MT-CO1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Sequence and organization of the human mitochondrial genome. (PubMed id 7219534)1, 2, 3 Anderson S.... Young I.G. (1981)
- Increased incidence of mitochondrial cytochrome c-oxidase gene mutations in patients with myelodysplastic syndromes. (PubMed id 11849212)1, 4, 9 Reddy P.L....Raza A. (2002)
- Arachidonate lipoxygenase (ALOX) and cyclooxygenase (COX) polymorphisms and colon cancer risk. (PubMed id 15308583)1, 4 Goodman J.E.... Harris C.C. (2004)
- Metabolic consequences of a novel missense mutation of the mtDNA CO I gene. (PubMed id 12140182)1, 2 Varlamov D.A....Kunz W.S. (2002)
- Correlation of the clinical severity of Alzheimer's disease with an aberration in mitochondrial DNA (mtDNA). (PubMed id 11345519)1, 4 Brown A.M....Blass J.P. (2001)
- Sequence variation in the mitochondrial gene cytochrome c oxidase subunit I and prostate cancer in African American men. (PubMed id 19267350)1, 9 Ray A.M....Petros J.A. (2009)
- A mitochondrial DNA variant, identified in Leber hereditary optic neuropathy patients, which extends the amino acid sequence of cytochrome c oxidase subunit I. (PubMed id 1322638)2, 9 Brown M.D....Wallace D.C. (1992)
- [Mutation of mitochondria cytochrome oxidase gene in patients with myelodysplastic syndrome] (PubMed id 18718066)1, 9 Hou L....Meng W.T. (2008)
- Interaction of mitochondrial thioredoxin with glucoco rticoid receptor and NF-kappaB modulates glucocorticoid receptor and NF-kappaB signalling in HEK-293 cells. (PubMed id 19570036)1, 9 Psarra A.M....Spyrou G. (2009)
- PGC-1alpha/beta upregulation is associated with improved oxidative phosphorylation in cells harboring nonsense mtDNA mutations. (PubMed id 17341490)1, 9 Srivastava S....Moraes C.T. (2007)
|
External Searches for MT-CO1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing MT-CO1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing MT-CO1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing MT-CO1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for MT-CO1 | Pharmacogenomics, SNPs, Pathways | | GeneReviews | http://www.ncbi.nlm.nih.gov/sites/GeneTests/lab/gene/MT-CO1 |
|
| | |
About This Section
| Patent Information for MT-CO1 gene:
Search GeneIP for patents involving MT-CO1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for MT-CO1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 |
| | | | |
 |
 |
|  | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat MT-CO1 | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MT-CO1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MT-CO1 | | | Search QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MT-CO1 | | | Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MT-CO1 | | | Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MT-CO1 |
| |
 |  |  |  | |
| | | | Search Tocris compounds for MT-CO1 |
| |  |  |  |  | | | | |
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 | | | MT-CO1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | |  |  |  |  | | | | ThermoFisher Antibody for MT-CO1 |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat MT-CO1 |
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