Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

MSTO1 Gene

protein-coding   GIFtS: 48
GCID: GC01P155580

misato homolog 1 (Drosophila)

 Explore 2 diseases affiliated with
MSTO1 via our new
 Human Malady Compendium 
Biological research products
for MSTO1
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Misato Homolog 1 (Drosophila)1 2
MST1 2
FLJ105041
LST0051
Protein Misato Homolog 12

External Ids:    HGNC: 296781   Entrez Gene: 551542   Ensembl: ENSG000001254597   UniProtKB: Q9BUK63   

Export aliases for MSTO1 gene to outside databases

Previous GC identifers: GC01P152396 GC01P153846 GC01P126941


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: MSTO1_HUMAN, Q9BUK6
Function: Involved in the regulation of mitochondrial distribution and morphology

Gene Wiki entry for MSTO1


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.1  NT_004487.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the MSTO1 gene promoter:
         HOXA9B   HOXA9   E2F-3a   E2F-4   E2F-5   E2F-2   E2F-1   E2F   Meis-1   RSRFC4   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMSTO1 promoter sequence
   Search SABiosciences Chromatin IP Primers for MSTO1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MSTO1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q22   Ensembl cytogenetic band:  1q22   HGNC cytogenetic band: 1q22

MSTO1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MSTO1 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P155580:  view genomic region     (about GC identifiers)

Start:
155,579,979 bp from pter      End:
155,718,153 bp from pter
Size:
138,175 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: MSTO1_HUMAN, Q9BUK6 (See protein sequence)
Recommended Name: Protein misato homolog 1  
Size: 570 amino acids; 61835 Da
Subcellular location: Mitochondrion outer membrane
Sequence caution: Sequence=AAM12424.1; Type=Frameshift; Positions=419;
Secondary accessions: Q53GR8 Q5CZ69 Q5T717 Q68CT6 Q7LBZ8 Q7Z3M7 Q7Z558 Q8TE05 Q9NQX2 Q9NVU4
Alternative splicing: 7 isoforms:  Q9BUK6-1   Q9BUK6-2   Q9BUK6-3   Q9BUK6-4   Q9BUK6-5   Q9BUK6-6   Q9BUK6-7   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for MSTO1: NX_Q9BUK6

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9BUK6

  • MSTO1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (3 alternative transcripts): 
    NP_001243461.1  NP_001243462.1  NP_060586.2  

    ENSEMBL proteins: 
     ENSP00000245564   ENSP00000357325   ENSP00000440200   ENSP00000444133  

    Human Recombinant Protein Products: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate: MSTO1
    OriGene Custom Protein Services for MSTO1 
    GenScript Custom Purified and Recombinant Proteins Services for MSTO1
    Novus Biologicals MSTO1 Protein
    Novus Biologicals MSTO1 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for MSTO1

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IDA--
    GO:0005741mitochondrial outer membrane IDA17349998
    GO:0043234protein complex IEA--


    MSTO1 for ontologies           About GeneDecksing



    MSTO1 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    OriGene Antibodies: MSTO1
    OriGene Custom Antibody Services for MSTO1 
    GenScript Custom Superior Antibodies Services for MSTO1
    Novus Biologicals MSTO1 Antibodies
    Search for Antibodies for MSTO1 at Abcam  
    Uscn Antibodies for MSTO1
    ThermoFisher Antibodies for MSTO1

    Assay Products for MSTO1: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Immunoassay Development
    Browse OriGene Fluorogenic Cell Assay Kits
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for MSTO1
    Browse Enzo Life Sciences for kits & assays
    Uscn ELISAs and CLIAs for MSTO1


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    MSTO1 for domains           About GeneDecksing

    2 InterPro domains/families:
     IPR003008 Tubulin_FtsZ_GTPase
     IPR019605 Misato_II_myosin-like

    Graphical View of Domain Structure for InterPro Entry Q9BUK6

    ProtoNet protein and cluster: Q9BUK6

    UniProtKB/Swiss-Prot: MSTO1_HUMAN, Q9BUK6
    Similarity: Belongs to the misato family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: MSTO1_HUMAN, Q9BUK6
    Function: Involved in the regulation of mitochondrial distribution and morphology

    miRNA
    Products:
        
    OriGene 3'-UTR Clone: MSTO1
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MSTO1
    8/18 QIAGEN miScript miRNA Assays for microRNAs that regulate MSTO1 (see all 18):
    hsa-miR-1287 hsa-miR-1224-3p hsa-miR-1260b hsa-miR-3921 hsa-miR-3692 hsa-miR-4267 hsa-miR-3605-5p hsa-miR-3908
    SwitchGear 3'UTR luciferase reporter plasmidMSTO1 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MSTO1 (see all 7)
    OriGene shRNA RFP: MSTO1
    OriGene siRNA: MSTO1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MSTO1

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for MSTO1

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MSTO1 (see all 3)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MSTO1 (see all 2)
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: MSTO1 (NM_018116)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MSTO1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MSTO1 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for MSTO1
    Search LifeMap BioReagents cell lines for MSTO1

    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MSTO1

    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--


    MSTO1 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for MSTO1:
     Decreased viability of wild-ty 


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MSTO1

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    5 Interacting proteins for MSTO1 (Q9BUK63 ENSP000002455644) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    UBE2DNLQ8IWF73I2D: score=1 
    UBCENSP000003448184STRING: ENSP00000344818
    CASP9ENSP000003302374STRING: ENSP00000330237
    EP300ENSP000002632534STRING: ENSP00000263253
    --ENSP000003424704STRING: ENSP00000342470
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007005mitochondrion organization IMP17349998
    GO:0048311mitochondrion distribution IMP17349998
    GO:0051258protein polymerization IEA--


    MSTO1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for MSTO1
    Search CenterWatch for drugs/clinical trials and news about MSTO1 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for MSTO1 gene (3 alternative transcripts): 
    NM_001256532.1  NM_001256533.1  NM_018116.3  

    Unigene Cluster for MSTO1:

    Misato homolog 1 (Drosophila)
    Hs.656547  [show with all ESTs]
    Unigene Representative Sequence: BC070067
    18/20 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 20):
    ENST00000488901 ENST00000460199 ENST00000490743 ENST00000471209 ENST00000245564(uc001fkw.3 uc001fkx.3 uc001fky.3 uc001fld.4 uc009wqs.3 uc010pgf.2)
    ENST00000368341 ENST00000494995(uc001flb.3) ENST00000482284 ENST00000490642
    ENST00000491308 ENST00000483832 ENST00000465137 ENST00000473327 ENST00000483734(uc001flc.3 uc001fla.3)
    ENST00000478756 ENST00000475253 ENST00000466815 ENST00000462250

    miRNA
    Products:
         
    OriGene 3'-UTR Clone: MSTO1
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MSTO1
    8/18 QIAGEN miScript miRNA Assays for microRNAs that regulate MSTO1 (see all 18):
    hsa-miR-1287 hsa-miR-1224-3p hsa-miR-1260b hsa-miR-3921 hsa-miR-3692 hsa-miR-4267 hsa-miR-3605-5p hsa-miR-3908
    SwitchGear 3'UTR luciferase reporter plasmidMSTO1 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MSTO1 (see all 7)
    OriGene shRNA RFP: MSTO1
    OriGene siRNA: MSTO1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MSTO1
    Clone
    Products:
         
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MSTO1 (see all 3)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MSTO1 (see all 2)
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: MSTO1 (NM_018116)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MSTO1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MSTO1 
    Primer
    Products:
        
    OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MSTO1
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat MSTO1
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MSTO1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MSTO1

    Additional cDNA sequence: 

    AF272833.1 AK001366.1 AK056128.1 AK092950.1 AK222863.1 AK290610.1 AK295146.1 AK297140.1 
    AK309573.1 AY334564.1 BC002535.2 BC070067.1 BX537684.1 CR749791.1 CR936872.1 NR_046292.1 
    NR_046293.1 NR_046294.1 NR_046295.1 

    24/32 DOTS entries (see all 32):

    DT.91775886  DT.100810628  DT.100809869  DT.97766349  DT.97862556  DT.113587  DT.121381154  DT.100785758 
    DT.95311424  DT.101984997  DT.95323269  DT.121381418  DT.95148787  DT.91775862  DT.121381218  DT.121381362 
    DT.204280  DT.113586  DT.91775859  DT.100810629  DT.121381452  DT.100785763  DT.100810632  DT.121381249 

    24/142 AceView cDNA sequences (see all 142):

    AA337242 AI682642 AF111708 AI434718 AI681580 CR623007 BM973963 AI422605 
    BU146956 AK092950 AL552143 AW512427 BC070067 BX345460 NM_018116 AA406570 
    BQ880348 AI657484 AX747823 BF508805 BQ675405 BI831680 AI422143 BE908101 

    GeneLoc Exon Structure

    5/18 Alternative Splicing Database (ASD) splice patterns (SP) for MSTO1 (see all 18)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e · 1f ^ 2 ^ 3a · 3b · 3c ^ 4 ^ 5a · 5b ^ 6 ^ 7a · 7b ^ 8a · 8b ^ 9 ^ 10 ^ 11 ^ 12a · 12b ^ 13 ^ 14a · 14b ·
    SP1:                                            -     -     -                 -     -     -     -     -     -     -     -     -     -     -     -     -     -   
    SP2:                                                                                -     -     -     -     -     -     -     -     -     -     -     -     -   
    SP3:                                            -     -     -           -     -     -     -     -     -     -     -     -     -     -     -     -     -     -   
    SP4:                                            -     -     -     -     -     -     -     -     -     -     -     -     -     -     -     -     -     -     -   
    SP5:                                            -     -     -                             -     -     -     -     -     -     -     -     -     -     -     -   

    ExUns: 14c ^ 15 ^ 16a · 16b · 16c ^ 17a · 17b ^ 18a · 18b · 18c ^ 19a · 19b · 19c ^ 20a · 20b · 20c · 20d ^ 21 ^ 22 ^ 23
    SP1:  -     -     -     -     -           -                                                                                 
    SP2:  -     -     -     -     -           -                                                                                 
    SP3:  -     -           -     -                                                                                             
    SP4:  -                 -     -                                                                                             
    SP5:  -     -     -     -     -     -     -                                                                                 


    ECgene alternative splicing isoforms for MSTO1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    MSTO1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TTAACATTTA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See MSTO1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for MSTO1

    SOURCE GeneReport for Unigene cluster: Hs.656547

    UniProtKB/Swiss-Prot: MSTO1_HUMAN, Q9BUK6
    Tissue specificity: Present in all cell lines tested (at protein level). Widely expressed

        SABiosciences Expression via Pathway-Focused PCR Array including MSTO1: 
              Mitochondria in human mouse rat

    Primer
    Products:
    OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MSTO1
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat MSTO1
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MSTO1
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MSTO1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MSTO1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for MSTO1 gene from 8/22 species (see all 22)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Msto11 , 5 misato homolog 1 (Drosophila)1, 5 83.15(n)1
    79.96(a)1
      3 (39.01 cM)5
    2295241  NM_144898.21  NP_659147.21 
     889051075 
    chicken
    (Gallus gallus)
    Aves MSTO11 misato homolog 1 (Drosophila) 59.17(n)
    56(a)
      425066  XM_422860.3  XP_422860.2 
    lizard
    (Anolis carolinensis)
    Reptilia MSTO16
    --
    52(a)
    1 ↔ 1
    GL343519.1(366887-379711)
    African clawed frog
    (Xenopus laevis)
    Amphibia CA986429.12   -- 75.77(n)    CA986429.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufi40a102 wufi40a10 73.46(n)   334306  BC044406.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta mst1 misato 43.04(n)
    32.1(a)
      33119  NM_078711.4  NP_523435.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT4G371901 hypothetical protein 40.6(n)
    30.98(a)
      829873  NM_119882.2  NP_195436.1 
    rice
    (Oryza sativa)
    Liliopsida Os03g02409001 hypothetical protein 43.32(n)
    31.91(a)
      4332207  NM_001056047.1  NP_001049512.1 


    ENSEMBL Gene Tree for MSTO1 (if available)
    TreeFam Gene Tree for MSTO1 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for MSTO1 gene

    MSTO1 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for MSTO1
    PGOHUM00000251137


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/129 NCBI SNPs in MSTO1 are shown (see all 129    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs352029811,2
    C,--155578042(+) CTCTAA/GTTCCT 7 -- us2k12Minor allele frequency- G:0.09NA 122
    rs341244161,2
    C,F,--155578049(+) TCCTGC/GGCTGA 7 -- us2k110Minor allele frequency- G:0.47NA WA CSA EA 370
    rs762682201,2
    F,--155578138(+) AGAGAG/AGATAG 7 -- us2k11Minor allele frequency- A:0.03WA 118
    rs1880573711,2
    --155578159(+) AGTCTA/CACTAC 7 -- us2k10--------
    rs1485300021,2
    --155578164(+) CACTAC/TATTGT 7 -- us2k10--------
    rs120775581,2
    C,--155578262(+) ctctgC/Tgccca 7 -- us2k12Minor allele frequency- T:0.17WA 120
    rs1807590901,2
    --155578331(+) TGTTGC/TCCAAG 7 -- us2k10--------
    rs1874602761,2
    --155578367(+) CTCACC/TGCAAG 7 -- us2k10--------
    rs1918232561,2
    --155578453(+) CACGCC/TCGGCT 7 -- us2k10--------
    rs1454776141,2
    --155578457(+) CCCGGC/TTAATT 7 -- us2k10--------

    HapMap Linkage Disequilibrium report for MSTO1 (155579979 - 155718153 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for MSTO1
         1 CNV: 6789

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MSTO1
    DNA2.0 Custom Variant and Variant Library Synthesis for MSTO1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    MSTO1 for disorders           About GeneDecksing

    2 diseases for MSTO1:    About MalaCards
    macular retinal edema    retinitis

    1 disease from the University of Copenhagen DISEASES database for MSTO1:
    Sick sinus syndrome

    Export disorders for MSTO1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for MSTO1 gene, integrated from 9 sources (see all 20):
    (articles sorted by number of sources associating them with MSTO1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Human Misato regulates mitochondrial distribution and morphology. (PubMed id 17349998)1, 2 Kimura M. and Okano Y. (2007)
    2. An anthropoid-specific segmental duplication on human chromosome 1q22. (PubMed id 16545939)1, 3 Kuryshev V.Y....Wiemann S. (2006)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
    5. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    6. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    7. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    8. A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (2008)
    9. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
    10. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 55154 HGNC: 29678 AceView: FLJ10504 Ensembl:ENSG00000125459 euGenes: HUgn55154
    ECgene: MSTO1 H-InvDB: MSTO1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for MSTO1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for MSTO1 gene:
    Search GeneIP for patents involving MSTO1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
    In Situ Hybridization Assays from
    Advanced Cell Diagnostics
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Phosphatase Activity Assays/Reagents   Browse Recombinant/Natural Proteins  
     OriGene Antibodies for MSTO1   OriGene shRNA RFP for MSTO1  
     OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MSTO1   OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MSTO1  
     OriGene Protein Over-expression Lysate for MSTO1   Browse OriGene Fluorogenic Cell Assay Kits  
     OriGene siRNA for MSTO1   OriGene 3'-UTR Clone for MSTO1  
     OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MSTO1   OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MSTO1  
     Browse OriGene GFP tagged cDNA clones in CMV expression vector   Browse OriGene MicroRNA Expression Plasmids  
     Browse OriGene basic RS shRNAs   Browse OriGene validated miRNA SYBR primer pairs  
     Browse OriGene full length recombinant human proteins expressed in human HEK293 cells   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for MSTO1   OriGene Custom Protein Services for MSTO1  
     OriGene Custom Immunoassay Development  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat MSTO1
     QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MSTO1
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MSTO1
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MSTO1
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MSTO1
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MSTO1
     GenScript Custom Purified and Recombinant Proteins Services for MSTO1 GenScript cDNA clones with any tag delivered in your preferred vector for MSTO1
     GenScript Custom Assay Services for MSTO1 GenScript Custom Superior Antibodies Services for MSTO1
     GenScript Custom overexpressing Cell Line Services for MSTO1 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in MSTO1 promoter
     Search Chromatin IP Primers for MSTO1
     RT2 qPCR Primer Assay in human, mouse, rat MSTO1
     Search GNC Networks for MSTO1
     SABiosciences PCR Arrays including human, mouse, rat MSTO1
     Search Tocris compounds for MSTO1
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological cDNA Clones
     Antibodies/Proteins Production Services
     Rabbit Monoclonal Antibody Platform
     Bulk Purchasing
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     MSTO1 antibodies
     MSTO1 proteins
     MSTO1 lysates
     Search for Antibodies for MSTO1 at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for MSTO1
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     MSTO1 Proteins, Antibodies, CLIAs, and ELISAs
     Search LifeMap BioReagents cell lines for MSTO1
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MSTO1
     SwitchGear 3'UTR luciferase reporter plasmids for MSTO1
     SwitchGear Promoter luciferase reporter plasmids for MSTO1
     ThermoFisher Antibodies for MSTO1
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MSTO1
           
    GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

    View Random Gene

    Category
    VWF
    (GIFTS: 73)
    von Willebrand factor
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      MSTO1 gene at Home site.
    hostname: 356980-web2.xennexinc.com index build: 100 solr: 1.4