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Aliases for MSTO1 Gene

Aliases for MSTO1 Gene

  • Misato 1, Mitochondrial Distribution And Morphology Regulator 2 3
  • Misato Homolog 1 (Drosophila) 2
  • Protein Misato Homolog 1 3
  • Misato Homolog 1 3
  • LST005 3
  • MST 3

External Ids for MSTO1 Gene

Summaries for MSTO1 Gene

GeneCards Summary for MSTO1 Gene

MSTO1 (Misato 1, Mitochondrial Distribution And Morphology Regulator) is a Protein Coding gene.

UniProtKB/Swiss-Prot for MSTO1 Gene

  • Involved in the regulation of mitochondrial distribution and morphology.

Gene Wiki entry for MSTO1 Gene

No data available for Entrez Gene Summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MSTO1 Gene

Genomics for MSTO1 Gene

Genomic Location for MSTO1 Gene

Start:
155,610,170 bp from pter
End:
155,614,967 bp from pter
Size:
4,798 bases
Orientation:
Plus strand

Genomic View for MSTO1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MSTO1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MSTO1 Gene

Regulatory Elements for MSTO1 Gene

Proteins for MSTO1 Gene

  • Protein details for MSTO1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9BUK6-MSTO1_HUMAN
    Recommended name:
    Protein misato homolog 1
    Protein Accession:
    Q9BUK6
    Secondary Accessions:
    • Q53GR8
    • Q5CZ69
    • Q5T717
    • Q68CT6
    • Q7LBZ8
    • Q7Z3M7
    • Q7Z558
    • Q8TE05
    • Q9NQX2
    • Q9NVU4

    Protein attributes for MSTO1 Gene

    Size:
    570 amino acids
    Molecular mass:
    61835 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAM12424.1; Type=Frameshift; Positions=419; Evidence={ECO:0000305};

    Alternative splice isoforms for MSTO1 Gene

neXtProt entry for MSTO1 Gene

Proteomics data for MSTO1 Gene at MOPED

Post-translational modifications for MSTO1 Gene

  • Modification sites at PhosphoSitePlus
  • Ubiquitination at Lys529

Other Protein References for MSTO1 Gene

No data available for DME Specific Peptides for MSTO1 Gene

Domains for MSTO1 Gene

Protein Domains for MSTO1 Gene

UniProtKB/Swiss-Prot:

MSTO1_HUMAN
Family:
  • Belongs to the misato family.:
    • Q9BUK6
genes like me logo Genes that share domains with MSTO1: view

No data available for Gene Families for MSTO1 Gene

Function for MSTO1 Gene

Molecular function for MSTO1 Gene

UniProtKB/Swiss-Prot Function: Involved in the regulation of mitochondrial distribution and morphology.

Gene Ontology (GO) - Molecular Function for MSTO1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
GO:0003924 GTPase activity IEA --
genes like me logo Genes that share ontologies with MSTO1: view

Phenotypes for MSTO1 Gene

genes like me logo Genes that share phenotypes with MSTO1: view

miRNA for MSTO1 Gene

miRTarBase miRNAs that target MSTO1

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for MSTO1 Gene

Localization for MSTO1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for MSTO1 Gene

Mitochondrion outer membrane.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for MSTO1 Gene COMPARTMENTS Subcellular localization image for MSTO1 gene
Compartment Confidence
mitochondrion 5
nucleus 2
peroxisome 2
cytosol 1

Gene Ontology (GO) - Cellular Components for MSTO1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IDA --
GO:0005741 mitochondrial outer membrane IDA 17349998
genes like me logo Genes that share ontologies with MSTO1: view

Pathways for MSTO1 Gene

SuperPathways for MSTO1 Gene

No Data Available

Interacting Proteins for MSTO1 Gene

Gene Ontology (GO) - Biological Process for MSTO1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007005 mitochondrion organization IMP 17349998
GO:0008152 metabolic process IEA --
GO:0048311 mitochondrion distribution IMP 17349998
genes like me logo Genes that share ontologies with MSTO1: view

No data available for Pathways by source for MSTO1 Gene

Transcripts for MSTO1 Gene

Unigene Clusters for MSTO1 Gene

Misato homolog 1 (Drosophila):
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for MSTO1 Gene

ExUns: 1a · 1b · 1c · 1d · 1e · 1f ^ 2 ^ 3a · 3b · 3c ^ 4 ^ 5a · 5b ^ 6 ^ 7a · 7b ^ 8a · 8b ^ 9 ^ 10 ^ 11 ^ 12a · 12b ^ 13 ^ 14a · 14b ·
SP1: - - - - - - - - - - - - - - - - -
SP2: - - - - - - - - - - - - -
SP3: - - - - - - - - - - - - - - - - - -
SP4: - - - - - - - - - - - - - - - - - - -
SP5: - - - - - - - - - - - - - - -
SP6: - - - - - - - - - - - - -
SP7: - - - - - - -
SP8:
SP9: - -
SP10: - - - - - - - - - - - - - - - - - - -
SP11: - - - - - - - - - - - - - - - - - -
SP12:
SP13: - - - - - - - - - -
SP14:
SP15:
SP16:
SP17:
SP18: - - - - - - - - - - - - - - - - -

ExUns: 14c ^ 15 ^ 16a · 16b · 16c ^ 17a · 17b ^ 18a · 18b · 18c ^ 19a · 19b · 19c ^ 20a · 20b · 20c · 20d ^ 21 ^ 22 ^ 23
SP1: - - - - - -
SP2: - - - - - -
SP3: - - - -
SP4: - - -
SP5: - - - - - - -
SP6: - - - - - - -
SP7: - - - - - - - - - - - - - - - - - -
SP8:
SP9: -
SP10: -
SP11: - -
SP12:
SP13: - - - - - - - - - - -
SP14:
SP15:
SP16:
SP17:
SP18:

Relevant External Links for MSTO1 Gene

GeneLoc Exon Structure for
MSTO1
ECgene alternative splicing isoforms for
MSTO1

Expression for MSTO1 Gene

mRNA expression in normal human tissues for MSTO1 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for MSTO1 Gene

SOURCE GeneReport for Unigene cluster for MSTO1 Gene Hs.656547

mRNA Expression by UniProt/SwissProt for MSTO1 Gene

Q9BUK6-MSTO1_HUMAN
Tissue specificity: Present in all cell lines tested (at protein level). Widely expressed.
genes like me logo Genes that share expressions with MSTO1: view

Orthologs for MSTO1 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for MSTO1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia MSTO1 36
  • 99.47 (n)
  • 99.47 (a)
MSTO1 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia MSTO1 36
  • 87.66 (n)
  • 87.02 (a)
MSTO1 37
  • 86 (a)
OneToOne
dog
(Canis familiaris)
Mammalia MSTO1 36
  • 84.62 (n)
  • 83.16 (a)
MSTO1 37
  • 82 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Msto1 36
  • 83.03 (n)
  • 79.68 (a)
Msto1 16
Msto1 37
  • 80 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia MSTO1 37
  • 77 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Msto1 36
  • 82.52 (n)
  • 81.56 (a)
chicken
(Gallus gallus)
Aves MSTO1 36
  • 59.22 (n)
  • 56.11 (a)
MSTO1 37
  • 51 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia MSTO1 37
  • 52 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia msto1 36
  • 56.42 (n)
  • 49.03 (a)
zebrafish
(Danio rerio)
Actinopterygii msto1 36
  • 53.37 (n)
  • 47.87 (a)
msto1 37
  • 43 (a)
OneToOne
wufi40a10 36
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP002778 36
  • 44.97 (n)
  • 35.47 (a)
fruit fly
(Drosophila melanogaster)
Insecta mst 36
  • 42.98 (n)
  • 32.1 (a)
mst 37
  • 29 (a)
OneToOne
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes DML1 39
thale cress
(Arabidopsis thaliana)
eudicotyledons AT4G37190 36
  • 40.57 (n)
  • 30.86 (a)
rice
(Oryza sativa)
Liliopsida Os03g0240900 36
  • 43.51 (n)
  • 31.91 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 37
  • 30 (a)
OneToOne
Species with no ortholog for MSTO1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MSTO1 Gene

ENSEMBL:
Gene Tree for MSTO1 (if available)
TreeFam:
Gene Tree for MSTO1 (if available)

Paralogs for MSTO1 Gene

Pseudogenes.org Pseudogenes for MSTO1 Gene

genes like me logo Genes that share paralogs with MSTO1: view

No data available for Paralogs for MSTO1 Gene

Variants for MSTO1 Gene

Sequence variations from dbSNP and Humsavar for MSTO1 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs379179 -- 155,611,487(-) GCTTC(A/G)TCCTC intron-variant, nc-transcript-variant, reference, missense
rs412421 -- 155,610,040(-) GTGAG(A/G)GGCGG upstream-variant-2KB
rs423975 -- 155,612,283(+) ATAAC(C/T)TGGGG reference, synonymous-codon, nc-transcript-variant
rs470548 -- 155,612,177(+) CCCCG(C/T)CCAGG intron-variant, missense, reference
rs470942 -- 155,610,141(+) TGCGG(A/G)CCAAT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MSTO1 Gene

Variant ID Type Subtype PubMed ID
esv33869 CNV Loss 17666407
esv2718418 CNV Deletion 23290073
nsv428246 CNV Gain 18775914
nsv436522 CNV Deletion 17901297
nsv3043 CNV Loss 18451855
nsv482134 CNV Gain 20164927

Relevant External Links for MSTO1 Gene

HapMap Linkage Disequilibrium report
MSTO1

Disorders for MSTO1 Gene

Relevant External Links for MSTO1

Genetic Association Database (GAD)
MSTO1
genes like me logo Genes that share disorders with MSTO1: view

No data available for UniProtKB/Swiss-Prot for MSTO1 Gene

Publications for MSTO1 Gene

  1. Human Misato regulates mitochondrial distribution and morphology. (PMID: 17349998) Kimura M. … Okano Y. (Exp. Cell Res. 2007) 2 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. An anthropoid-specific segmental duplication on human chromosome 1q22. (PMID: 16545939) Kuryshev V.Y. … Wiemann S. (Genomics 2006) 2 3
  4. From ORFeome to biology: a functional genomics pipeline. (PMID: 15489336) Wiemann S. … Poustka A. (Genome Res. 2004) 3
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3

Products for MSTO1 Gene

Sources for MSTO1 Gene

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