Aliases for MSTN Gene
External Ids for MSTN Gene
Previous Symbols for MSTN Gene
The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. This gene is thought to encode a secreted protein which negatively regulates skeletal muscle growth. [provided by RefSeq, Jul 2008]
GeneCards Summary for MSTN Gene
MSTN (Myostatin) is a Protein Coding gene. Diseases associated with MSTN include myostatin-related muscle hypertrophy and alcoholic cardiomyopathy. Among its related pathways are TGF-beta Signaling Pathway (sino) and Hypertrophy Model. GO annotations related to this gene include identical protein binding and cytokine activity. An important paralog of this gene is INHBB.
UniProtKB/Swiss-Prot for MSTN Gene
Acts specifically as a negative regulator of skeletal muscle growth