Aliases for MST1R Gene
Aliases for MST1R Gene
External Ids for MST1R Gene
- HGNC: 7381
- Entrez Gene: 4486
- Ensembl: ENSG00000164078
- OMIM: 600168
- UniProtKB: Q04912
Previous HGNC Symbols for MST1R Gene
- RON
- PTK8
Previous GeneCards Identifiers for MST1R Gene
- GC03P050091
- GC03P050215
- GC03M049778
- GC03M049884
- GC03M049885
- GC03M049899
Summaries for MST1R Gene
-
This gene encodes a cell surface receptor for macrophage-stimulating protein (MSP) with tyrosine kinase activity. The mature form of this protein is a heterodimer of disulfide-linked alpha and beta subunits, generated by proteolytic cleavage of a single-chain precursor. The beta subunit undergoes tyrosine phosphorylation upon stimulation by MSP. This protein is expressed on the ciliated epithelia of the mucociliary transport apparatus of the lung, and together with MSP, thought to be involved in host defense. Alternative splicing generates multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing. [provided by RefSeq, Jan 2016]
GeneCards Summary for MST1R Gene
MST1R (Macrophage Stimulating 1 Receptor) is a Protein Coding gene. Diseases associated with MST1R include Nasopharyngeal Carcinoma 3 and Nasopharyngeal Carcinoma. Among its related pathways are ERK Signaling and Actin Nucleation by ARP-WASP Complex. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is MET.
UniProtKB/Swiss-Prot for MST1R Gene
-
Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to MST1 ligand. Regulates many physiological processes including cell survival, migration and differentiation. Ligand binding at the cell surface induces autophosphorylation of RON on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1 or the adapter GAB1. Recruitment of these downstream effectors by RON leads to the activation of several signaling cascades including the RAS-ERK, PI3 kinase-AKT, or PLCgamma-PKC. RON signaling activates the wound healing response by promoting epithelial cell migration, proliferation as well as survival at the wound site. Plays also a role in the innate immune response by regulating the migration and phagocytic activity of macrophages. Alternatively, RON can also promote signals such as cell migration and proliferation in response to growth factors other than MST1 ligand.
Additional gene information for MST1R Gene
- Monarch Initiative
- Search for MST1R at DataMed
- Search for MST1R at HumanCyc
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MST1R Gene
Genomics for MST1R Gene
GeneHancer (GH) Regulatory Elements for MST1R Gene
Promoters and enhancers for MST1R Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around MST1R on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for MST1R Gene
Genomic Locations for MST1R Gene
- chr3:49,886,981-49,903,873
- (GRCh38/hg38)
- Size:
- 16,893 bases
- Orientation:
- Minus strand
- chr3:49,924,435-49,941,306
- (GRCh37/hg19)
Genomic View for MST1R Gene
Genes around MST1R on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 3p21.31 by Ensembl
- 3p21.31 by Entrez Gene
- 3p21.31 by HGNC
MST1R Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for MST1R Gene
Proteins for MST1R Gene
-
Protein details for MST1R Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q04912-RON_HUMAN
- Recommended name:
- Macrophage-stimulating protein receptor
- Protein Accession:
- Q04912
- B5A944
- B5A945
- B5A946
- B5A947
Protein attributes for MST1R Gene
- Size:
- 1400 amino acids
- Molecular mass:
- 152271 Da
- Quaternary structure:
-
- Heterodimer of an alpha chain and a beta chain which are disulfide linked. Binds PLXNB1. Associates with and is negatively regulated by HYAL2. Interacts when phosphorylated with downstream effectors including PIK3R1, PCLG1, GRB2 and GAB1. Interacts with integrin beta1/ITGB1 in a ligand-independent fashion.
Protein Expression for MST1R Gene
Selected DME Specific Peptides for MST1R Gene
- Q04912:
-
- QVARGME
- RDLAARN
- LPVKWMA
- QPEYCPD
- FTVKVADFGLAR
- KSDVWSFG
- WMALESL
- FVHRDLA
- DFGLARDI
Post-translational modifications for MST1R Gene
- Autophosphorylated in response to ligand binding on Tyr-1238 and Tyr-1239 in the kinase domain leading to further phosphorylation of Tyr-1353 and Tyr-1360 in the C-terminal multifunctional docking site.
- Proteolytic processing yields the two subunits.
- Ubiquitinated. Ubiquitination by CBL regulates the receptor stability and activity through proteasomal degradation.
- Glycosylation at Asn66, Asn419, Asn458, Asn488, Asn654, isoforms=2, 5720, isoforms=2, 5841, and isoforms=897
Other Protein References for MST1R Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- R&D Systems Antibodies for MST1R (MSP R/Ron)
- Cell Signaling Technology (CST) Antibodies for MST1R (Ron)
-
Custom Antibody ServicesOriGene Antibodies for MST1R
- Novus Biologicals Antibodies for MST1R
-
Abcam antibodies for MST1R
-
Cloud-Clone Corp. Antibodies for MST1R
- Invitrogen Antibodies for MST1R
- antibodies-online: Search results for 214 available MST1R Antibodies ranked by validation data
- Compare Top MST1R Antibodies
-
Recommended
- 93 WB Antibodies (anti-human)
- 24 IF (p) Antibodies (anti-human)
- 20 IHC (p) Antibodies (anti-human)
- 5 FACS Antibodies (anti-human)
- 5 IHC Antibodies (anti-human)
- 1 Neut Antibody (anti-human)
- 44 WB Antibodies (anti-mouse)
- 24 IF (p) Antibodies (anti-mouse)
- 2 IHC (p) Antibodies (anti-mouse)
- 24 IF (p) Antibodies (anti-rat)
- 12 WB Antibodies (anti-rat)
- 93 WB Antibodies (anti-human)
- 24 IF (p) Antibodies (anti-human)
- 20 IHC (p) Antibodies (anti-human)
- 5 FACS Antibodies (anti-human)
- 5 IHC Antibodies (anti-human)
- 1 Neut Antibody (anti-human)
- 44 WB Antibodies (anti-mouse)
- 24 IF (p) Antibodies (anti-mouse)
- 2 IHC (p) Antibodies (anti-mouse)
- 24 IF (p) Antibodies (anti-rat)
- 12 WB Antibodies (anti-rat)
- Search GeneTex for Antibodies for MST1R
-
Santa Cruz Biotechnology (SCBT) Antibodies for MST1R
- Sino Biological Antibodies for MST1R
Protein Products
- R&D Systems Proteins and Enzymes for MST1R (MSP R/Ron)
-
OriGene Purified Proteins for MST1R
- Search Origene for MassSpec and Protein Over-expression Lysates for MST1R
- Origene Custom Protein Services for MST1R
- Sino Biological Cell Lysates for MST1R
- Sino Biological Recombinant Proteins for MST1R
-
Cloud-Clone Corp. Proteins for MST1R
- Search GeneTex for Proteins for MST1R
-
Abcam proteins for MST1R
Assay Products
- R&D Systems ELISAs, Proteome Profiler Antibody Arrays, and other biochemical assays for MST1R (MSP R/Ron)
- Cell Signaling Technology (CST) Sandwich ELISA Kits for MST1R (Ron)
Domains & Families for MST1R Gene
Gene Families for MST1R Gene
- HGNC:
- IUPHAR :
- Human Protein Atlas (HPA):
-
- CD markers
- Disease related genes
- Enzymes
- Potential drug targets
- Predicted intracellular proteins
- Predicted membrane proteins
Protein Domains for MST1R Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for MST1R Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q04912UniProtKB/Swiss-Prot:
RON_HUMAN :- Belongs to the protein kinase superfamily. Tyr protein kinase family.
- Family:
-
- Belongs to the protein kinase superfamily. Tyr protein kinase family.
Function for MST1R Gene
Molecular function for MST1R Gene
- GENATLAS Biochemistry:
- macrophage stimulating protein 1 receptor,hepacyte growth factor receptor (MET) related,involved in development of epithelial tissue,bone,neuroendocrine derivatives,paralog to MET,stem cell tyrosine kinase receptor (Stk) homolog,conferring susceptibility to friend virus induced erythroleukemia in mice
- UniProtKB/Swiss-Prot CatalyticActivity:
- ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.
- UniProtKB/Swiss-Prot EnzymeRegulation:
- In its inactive state, the C-terminal tail interacts with the catalytic domain and inhibits the kinase activity. Upon ligand binding, the C-terminal tail is displaced and becomes phosphorylated, thus increasing the kinase activity.
- UniProtKB/Swiss-Prot Function:
- Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to MST1 ligand. Regulates many physiological processes including cell survival, migration and differentiation. Ligand binding at the cell surface induces autophosphorylation of RON on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1 or the adapter GAB1. Recruitment of these downstream effectors by RON leads to the activation of several signaling cascades including the RAS-ERK, PI3 kinase-AKT, or PLCgamma-PKC. RON signaling activates the wound healing response by promoting epithelial cell migration, proliferation as well as survival at the wound site. Plays also a role in the innate immune response by regulating the migration and phagocytic activity of macrophages. Alternatively, RON can also promote signals such as cell migration and proliferation in response to growth factors other than MST1 ligand.
Enzyme Numbers (IUBMB) for MST1R Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0004672 | protein kinase activity | IEA | -- |
| GO:0004713 | protein tyrosine kinase activity | IEA | -- |
| GO:0004714 | transmembrane receptor protein tyrosine kinase activity | IEA | -- |
| GO:0005011 | macrophage colony-stimulating factor receptor activity | TAS | 9045873 |
| GO:0005515 | protein binding | IPI | 15184888 |
Phenotypes for MST1R Gene
- MGI mutant phenotypes for MST1R:
- inferred from 6 alleles
- GenomeRNAi human phenotypes for MST1R:
-
- shRNA abundance <= 50%
- Decreased viability ratio
- Increased transferrin (TF) endocytosis
- Increased shRNA abundance (Z-score > 2)
- Decreased viability
- Decreased substrate adherent cell growth
- Decreased shRNA abundance (Z-score < -2)
- Decreased focal adhesion (FA) area, decreased FA length, decreased FA mean intensity, increased number of small and round FAs, increased FA abundance
- Decreased cell migration
- Increased cell death HMECs cells
- Decreased influenza A/WSN/33 replication
- Synthetic lethal with vaccinia virus (VACV) infection
- Decreased human cytomegalovirus (HCMV) strain AD169 replication
- Decreased cell proliferation
- Increased cell migration
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for MST1R
-
-
ViGene Biosciences lentiviral particle packaged cDNA for MST1R gene
-
ViGene Biosciences ready-to-package AAV shRNAs for MST1R gene
- Search ViGene Biosciences for MST1R
CRISPR Products
-
OriGene CRISPR knockouts for MST1R
- genomics-online: gRNA clones - Search results for 75 available MST1R gene related products
- Overview of 75 available MST1R gene related products
-
Recommended
- pCMV6-Entry
- pCMV6-XL4
- pCMV6-XL5
- pcDNA3.1+C-(K)-DYK
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pRFP-C-RS
- pGFP-V-RS
- pGFP-C-shLenti
- pCMV6-Entry
- pCMV6-XL4
- pCMV6-XL5
- pcDNA3.1+C-(K)-DYK
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pRFP-C-RS
- pGFP-V-RS
- pGFP-C-shLenti
- Applied Biological Materials CRISPR for MST1R
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for MST1R
- GenScript: Design CRISPR guide RNA sequences for MST1R
miRNA for MST1R Gene
- miRTarBase miRNAs that target MST1R
miRNA Products
- Search ViGene Biosciences for MST1R
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for MST1R
- Browse OriGene Inhibitory RNA Products For MST1R
- genomics-online: shRNA clones - Search results for 75 available MST1R gene related products
- Overview of 75 available MST1R gene related products
-
Recommended
- pCMV6-Entry
- pCMV6-XL4
- pCMV6-XL5
- pcDNA3.1+C-(K)-DYK
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pRFP-C-RS
- pGFP-V-RS
- pGFP-C-shLenti
- pCMV6-Entry
- pCMV6-XL4
- pCMV6-XL5
- pcDNA3.1+C-(K)-DYK
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pRFP-C-RS
- pGFP-V-RS
- pGFP-C-shLenti
-
ViGene Biosciences ready-to-package AAV shRNAs for MST1R gene
Clone Products
- VectorBuilder custom plasmid, inducible vectors for MST1R
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MST1R
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for MST1R
- genomics-online: cdna clones - Search results for 75 available MST1R gene related products
- Overview of 75 available MST1R gene related products
-
Recommended
- pCMV6-Entry
- pCMV6-XL4
- pCMV6-XL5
- pcDNA3.1+C-(K)-DYK
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pRFP-C-RS
- pGFP-V-RS
- pGFP-C-shLenti
- pCMV6-Entry
- pCMV6-XL4
- pCMV6-XL5
- pcDNA3.1+C-(K)-DYK
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pRFP-C-RS
- pGFP-V-RS
- pGFP-C-shLenti
- orf clones - Search results for 75 available MST1R gene related products
- Overview of 75 available MST1R gene related products
-
Recommended
- pCMV6-Entry
- pCMV6-XL4
- pCMV6-XL5
- pcDNA3.1+C-(K)-DYK
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pRFP-C-RS
- pGFP-V-RS
- pGFP-C-shLenti
- pCMV6-Entry
- pCMV6-XL4
- pCMV6-XL5
- pcDNA3.1+C-(K)-DYK
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pRFP-C-RS
- pGFP-V-RS
- pGFP-C-shLenti
- Applied Biological Materials Clones for MST1R
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
- R&D Systems cDNA Clones for MST1R (MSP R/Ron)
Cell Line Products
-
Horizon Cell Lines for MST1R
-
ViGene Biosciences adenoviral particle packaged cDNA for MST1R gene
-
ViGene Biosciences lentiviral particle packaged cDNA for MST1R gene
-
ViGene Biosciences ready-to-package AAV shRNAs for MST1R gene
No data available for Phenotypes From GWAS Catalog , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for MST1R Gene
Localization for MST1R Gene
Subcellular locations from UniProtKB/Swiss-Prot for MST1R Gene
- Membrane; Single-pass type I membrane protein.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| cytoskeleton | 3 |
| extracellular | 2 |
| mitochondrion | 1 |
| peroxisome | 1 |
| nucleus | 1 |
| endoplasmic reticulum | 1 |
| cytosol | 1 |
- Cytosol (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0001725 | stress fiber | IEA | -- |
| GO:0005773 | vacuole | IEA | -- |
| GO:0005886 | plasma membrane | TAS | -- |
| GO:0005887 | integral component of plasma membrane | TAS | 7939629 |
| GO:0009986 | cell surface | IDA,HDA | 19581412 |
Pathways & Interactions for MST1R Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | GPCR Pathway |
.73
.62
|
.55
|
| 2 | ERK Signaling |
.61
.58
|
.49
|
| 3 | Nanog in Mammalian ESC Pluripotency |
.61
|
.48
|
| 4 | Actin Nucleation by ARP-WASP Complex |
.41
|
|
| 5 | Activation of cAMP-Dependent PKA | ||
Pathways by source for MST1R Gene
2 Cell Signaling Technology pathways for MST1R Gene
2 BioSystems pathways for MST1R Gene
2 Reactome pathways for MST1R Gene
Interacting Proteins for MST1R Gene
Selected Interacting proteins:
Q04912-RON_HUMAN
ENSP00000296474
for MST1R Gene via
IID
STRING
UniProtKB
MINT
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0002376 | immune system process | IEA | -- |
| GO:0006468 | protein phosphorylation | IEA | -- |
| GO:0006928 | movement of cell or subcellular component | TAS | 9045873 |
| GO:0006952 | defense response | TAS | 9045873 |
| GO:0007165 | signal transduction | TAS | 7939629 |
Drugs & Compounds for MST1R Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| foretinib | Investigational | Pharma | inhibitor | Kinase Inhibitors, Vascular endothelial growth factor (VEGF) and VEGF receptor (VEGFR) inhibitors | 0 | |
| ATP | Investigational | Nutra | Agonist | 0 | ||
| macrophage stimulating protein 1 | Pharma | 0 | ||||
| Foretinib (GSK1363089) | Pharma | VEGF and HGF receptor inhibitor | 0 | |||
| MGCD-265 | Pharma | Met/Flt/Flk/Ron/Tie-2 inhibitor | 0 |
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
|---|---|---|---|---|---|---|
| ADP |
|
Full agonist, Agonist | 58-64-0 |
|
(2) ApexBio Compounds for MST1R Gene
| Compound | Action | Cas Number |
|---|---|---|
| Foretinib (GSK1363089) | VEGF and HGF receptor inhibitor | 849217-64-7 |
| MGCD-265 | Met/Flt/Flk/Ron/Tie-2 inhibitor | 875337-44-3 |
Transcripts for MST1R Gene
mRNA/cDNA for MST1R Gene
- (10) REFSEQ mRNAs :
- (8) Additional mRNA sequences :
- (72) Selected AceView cDNA sequences:
- (15) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for MST1R Gene
CRISPR Products
-
OriGene CRISPR knockouts for MST1R
- genomics-online: gRNA clones - Search results for 75 available MST1R gene related products
- Overview of 75 available MST1R gene related products
-
Recommended
- pCMV6-Entry
- pCMV6-XL4
- pCMV6-XL5
- pcDNA3.1+C-(K)-DYK
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pRFP-C-RS
- pGFP-V-RS
- pGFP-C-shLenti
- pCMV6-Entry
- pCMV6-XL4
- pCMV6-XL5
- pcDNA3.1+C-(K)-DYK
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pRFP-C-RS
- pGFP-V-RS
- pGFP-C-shLenti
- Applied Biological Materials CRISPR for MST1R
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for MST1R
- GenScript: Design CRISPR guide RNA sequences for MST1R
miRNA Products
- Search ViGene Biosciences for MST1R
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for MST1R
- Browse OriGene Inhibitory RNA Products For MST1R
- genomics-online: shRNA clones - Search results for 75 available MST1R gene related products
- Overview of 75 available MST1R gene related products
-
Recommended
- pCMV6-Entry
- pCMV6-XL4
- pCMV6-XL5
- pcDNA3.1+C-(K)-DYK
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pRFP-C-RS
- pGFP-V-RS
- pGFP-C-shLenti
- pCMV6-Entry
- pCMV6-XL4
- pCMV6-XL5
- pcDNA3.1+C-(K)-DYK
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pRFP-C-RS
- pGFP-V-RS
- pGFP-C-shLenti
-
ViGene Biosciences ready-to-package AAV shRNAs for MST1R gene
Clone Products
- VectorBuilder custom plasmid, inducible vectors for MST1R
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MST1R
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for MST1R
- genomics-online: cdna clones - Search results for 75 available MST1R gene related products
- Overview of 75 available MST1R gene related products
-
Recommended
- pCMV6-Entry
- pCMV6-XL4
- pCMV6-XL5
- pcDNA3.1+C-(K)-DYK
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pRFP-C-RS
- pGFP-V-RS
- pGFP-C-shLenti
- pCMV6-Entry
- pCMV6-XL4
- pCMV6-XL5
- pcDNA3.1+C-(K)-DYK
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pRFP-C-RS
- pGFP-V-RS
- pGFP-C-shLenti
- orf clones - Search results for 75 available MST1R gene related products
- Overview of 75 available MST1R gene related products
-
Recommended
- pCMV6-Entry
- pCMV6-XL4
- pCMV6-XL5
- pcDNA3.1+C-(K)-DYK
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pRFP-C-RS
- pGFP-V-RS
- pGFP-C-shLenti
- pCMV6-Entry
- pCMV6-XL4
- pCMV6-XL5
- pcDNA3.1+C-(K)-DYK
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pRFP-C-RS
- pGFP-V-RS
- pGFP-C-shLenti
- Applied Biological Materials Clones for MST1R
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
- R&D Systems cDNA Clones for MST1R (MSP R/Ron)
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | ^ | 9 | ^ | 10 | ^ | 11a | · | 11b | ^ | 12 | ^ | 13a | · | 13b | ^ | 14a | · | 14b | ^ | 15a | · | 15b | · | 15c | ^ | 16a | · | 16b | ^ | 17 | ^ | 18 | ^ | 19 | ^ |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP3: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP4: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP5: |
| ExUns: | 20 |
|---|---|
| SP1: | |
| SP2: | |
| SP3: | |
| SP4: | |
| SP5: |
Expression for MST1R Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
mRNA differential expression in normal tissues according to GTEx for MST1R Gene
This gene is overexpressed in Colon - Transverse (x7.7), Stomach (x6.1), Skin - Sun Exposed (Lower leg) (x5.4), and Skin - Not Sun Exposed (Suprapubic) (x5.3).
This gene is overexpressed in Stomach (40.3) and Heart (24.7).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for MST1R Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of MST1R Gene:
MST1RSOURCE GeneReport for Unigene cluster for MST1R Gene:
Hs.517973mRNA Expression by UniProt/SwissProt for MST1R Gene:
Q04912-RON_HUMAN
Tissue specificity:
Expressed in colon, skin, lung and bone marrow.
Evidence on tissue expression from TISSUES for MST1R Gene
- Skin(4.5)
- Intestine(2.3)
- Stomach(2.2)
- Lung(2)
Primer Products
-
OriGene qPCR primer pairs for MST1R
- genomics-online: primer clones - Search results for 75 available MST1R gene related products
- Overview of 75 available MST1R gene related products
-
Recommended
- pCMV6-Entry
- pCMV6-XL4
- pCMV6-XL5
- pcDNA3.1+C-(K)-DYK
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pRFP-C-RS
- pGFP-V-RS
- pGFP-C-shLenti
- pCMV6-Entry
- pCMV6-XL4
- pCMV6-XL5
- pcDNA3.1+C-(K)-DYK
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pRFP-C-RS
- pGFP-V-RS
- pGFP-C-shLenti
No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for MST1R Gene
Orthologs for MST1R Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | MST1R 33 34 |
|
||
| cow (Bos Taurus) |
Mammalia | MST1R 33 34 |
|
||
| dog (Canis familiaris) |
Mammalia | MST1R 34 33 |
|
OneToOne | |
| mouse (Mus musculus) |
Mammalia | Mst1r 33 16 34 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Mst1r 33 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | MST1R 34 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | MST1R 34 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | MST1R 33 34 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | MST1R 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | LOC100496572 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | mst1rb 33 34 |
|
||
| mst1ra 34 |
|
OneToMany | |||
| fruit fly (Drosophila melanogaster) |
Insecta | hop 35 |
|
|
|
| worm (Caenorhabditis elegans) |
Secernentea | F11E6.8 35 |
|
|
|
| T14E8.1b 35 |
|
|
|||
| T14E8.1a 35 |
|
|
|||
| W04G5.10 35 |
|
|
|||
| F09A5.2 35 |
|
|
|||
| kin-23 35 |
|
|
|||
| old-2 35 |
|
|
|||
| kin-16 35 |
|
|
|||
| old-1 35 |
|
|
|||
| svh-2 34 |
|
OneToMany | |||
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 34 |
|
OneToMany |
- Species where no ortholog for MST1R was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for MST1R Gene
(80) SIMAP similar genes for MST1R Gene using alignment to 4 proteins:
- RON
- FLT4
- FLT1
- EPHA2
- BTK kinase deficient isoform 6
- tec
- ABL1
- SRC
- AXL
- TPM3-ROS1
- SLC34A2-ROS1
- SDC4-ROS1_S4
- R34
- SDC4-ROS1_S4
- R32
- SDC4-ROS1_S2
- R32
- LRIG3(NM_153377)-ROS1
- LRIG3(NM_001136051)-ROS1
- EZR-ROS1
- CD74-ROS1_C6
- R32
- CSK
- FES
- HCK
- BLK
- FGR
- RYK
- EPHA6
- EPHA3
- MERTK
- DKFZp434L0319
- BTK kinase deficient isoform 2
- FGFR1
- TYRO3
- EPHA5
- ERBB4
- PTK2
- urf-ret
- PTK7
- SQSTM1-ALK
- RET
- PPFIBP1-ALK
- NTRK1
- KIF5B-RET(NM_020975)_K23
- R12
- KIF5B-RET(NM_020975)_K22
- R12
- KIF5B-RET(NM_020975)_K16
- R12
- KIF5B-RET(NM_020975)_K15
- R12
- KIF5B-RET(NM_020630)_K24
- R11
- KIF5B-RET(NM_020630)_K23
- R12
- KIF5B-RET(NM_020630)_K22
- R12
- KIF5B-RET(NM_020630)_K16
- R12
- KIF5B-RET(NM_020630)_K15
- R12
- KIF5B-ALK_K17
- A20
- ERBB2
- EML4-ALK
- DDR1
- CCDC6-RETc
- CCDC6-RETa
- ALK
- MET
- LTK
- EGFR
- FGFR3
- TNK2
- FGFR2
- DKFZp686M05208
- TIE1
- FGFR4
- TYK2
Variants for MST1R Gene
| SNP ID | Clin | Chr 03 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs200046052 | risk-factor, Nasopharyngeal carcinoma, susceptibility to, 3 | 49,902,693(-) | C/G/T | coding_sequence_variant, missense_variant, non_coding_transcript_variant | |
| rs35986685 | benign, not specified, not provided | 49,898,093(-) | T/G | coding_sequence_variant, missense_variant, non_coding_transcript_variant | |
| VAR_076928 | Nasopharyngeal carcinoma, 3 (NPCA3) [MIM:617075] | p.Arg306His | |||
| VAR_076929 | Nasopharyngeal carcinoma, 3 (NPCA3) [MIM:617075] | p.Ala327Thr | |||
| VAR_076930 | Nasopharyngeal carcinoma, 3 (NPCA3) [MIM:617075] | p.Val670Gly |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv890e214 | CNV | loss | 21293372 |
| esv3596133 | CNV | gain | 21293372 |
| nsv1074591 | CNV | deletion | 25765185 |
| nsv834688 | CNV | loss | 17160897 |
Residual Variation Intolerance Score:
4.02% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
6.05;
75.15% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for MST1R Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MST1R Gene
Disorders for MST1R Gene
(6) MalaCards diseases for MST1R Gene - From: HGMD, OMIM, ClinVar, Swiss-Prot, DISEASES, Novoseek, and GeneCards
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| nasopharyngeal carcinoma 3 |
|
|
| nasopharyngeal carcinoma |
|
|
| renal oncocytoma |
|
|
| papillary adenocarcinoma |
|
|
| adenocarcinoma |
|
|
Search MST1R in MalaCards
View complete list of genes associated with diseases
UniProtKB/Swiss-Prot
RON_HUMAN- Nasopharyngeal carcinoma, 3 (NPCA3) [MIM:617075]: A form of nasopharyngeal carcinoma, a malignant neoplasm that originates in the nasopharyngeal epithelium and includes 4 subtypes: keratinizing squamous cell, non-keratinizing, basaloid squamous cell, and papillary adenocarcinoma. {ECO:0000269 PubMed:26951679}. Note=Disease susceptibility is associated with variations affecting the gene represented in this entry.
Additional Disease Information for MST1R
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for Genatlas for MST1R Gene
Publications for MST1R Gene
- A novel putative receptor protein tyrosine kinase of the met family. (PMID: 8386824) Ronsin C … Breathnach R (Oncogene 1993) 2 3 4 22 58
- Interplay between scatter factor receptors and B plexins controls invasive growth. (PMID: 15184888) Conrotto P … Giordano S (Oncogene 2004) 3 4 22 58
- c-Cbl is a critical modulator of the Ron tyrosine kinase receptor. (PMID: 12802274) Penengo L … Gaudino G (Oncogene 2003) 3 4 22 58
- Identification of the ron gene product as the receptor for the human macrophage stimulating protein. (PMID: 7939629) Wang MH … Breathnach R (Science (New York, N.Y.) 1994) 3 4 22 58
- RON is a heterodimeric tyrosine kinase receptor activated by the HGF homologue MSP. (PMID: 8062829) Gaudino G … Comoglio PM (The EMBO journal 1994) 3 4 22 58
Products for MST1R Gene
- R&D Systems Antibodies for MST1R (MSP R/Ron)
- R&D Systems Proteins and Enzymes for MST1R (MSP R/Ron)
- R&D Systems ELISAs, Proteome Profiler Antibody Arrays, and other biochemical assays for MST1R (MSP R/Ron)
- R&D Systems cDNA Clones for MST1R (MSP R/Ron)
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- Search for Antibodies & Assays
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- Browse Primary Antibodies
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- Cloud-Clone Corp. Antibodies for MST1R
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- Browse Assay Kits at Cloud-Clone Corp.
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- Cloud-Clone Corp. disease models service
- Browse cDNA clones at Cloud-Clone Corp.
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- Cloud-Clone Corp. primary cells service
- Invitrogen Antibodies for MST1R
- ApexBio compounds for MST1R
- Cyagen custom Knockout/knockin (KOKI) mouse models for MST1R
- VectorBuilder custom plasmid, inducible vectors for MST1R
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MST1R
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for MST1R
- antibodies-online: Search results for 214 available MST1R Antibodies ranked by validation data
- Compare Top MST1R Antibodies
- Recommended
- 93 WB Antibodies (anti-human)
- 24 IF (p) Antibodies (anti-human)
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- 5 FACS Antibodies (anti-human)
- 5 IHC Antibodies (anti-human)
- 1 Neut Antibody (anti-human)
- 44 WB Antibodies (anti-mouse)
- 24 IF (p) Antibodies (anti-mouse)
- 2 IHC (p) Antibodies (anti-mouse)
- 24 IF (p) Antibodies (anti-rat)
- 12 WB Antibodies (anti-rat)
- 93 WB Antibodies (anti-human)
- 24 IF (p) Antibodies (anti-human)
- 20 IHC (p) Antibodies (anti-human)
- 5 FACS Antibodies (anti-human)
- 5 IHC Antibodies (anti-human)
- 1 Neut Antibody (anti-human)
- 44 WB Antibodies (anti-mouse)
- 24 IF (p) Antibodies (anti-mouse)
- 2 IHC (p) Antibodies (anti-mouse)
- 24 IF (p) Antibodies (anti-rat)
- 12 WB Antibodies (anti-rat)
- antibodies-online: Search results for 9 available MST1R Elisa Kits ranked by validation data
- Compare Top MST1R Elisa Kits
- antibodies-online: Search results for 20 available MST1R Proteins ranked by validation data
- Compare Top MST1R Proteins
- Search GeneTex for Antibodies for MST1R
- Search GeneTex for Proteins for MST1R
- ViGene Biosciences adenoviral particle packaged cDNA for MST1R gene
- ViGene Biosciences lentiviral particle packaged cDNA for MST1R gene
- ViGene Biosciences ready-to-package AAV shRNAs for MST1R gene
- Search ViGene Biosciences for MST1R
- Santa Cruz Biotechnology (SCBT) Antibodies for MST1R
- Search Santa Cruz Biotechnology (SCBT) for MST1R siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for MST1R
- Horizon Cell Lines for MST1R
- genomics-online: cdna clones - Search results for 75 available MST1R gene related products
- Overview of 75 available MST1R gene related products
- Recommended
- pCMV6-Entry
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- pLenti-C-mGFP
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pRFP-C-RS
- pGFP-V-RS
- pGFP-C-shLenti
- orf clones - Search results for 75 available MST1R gene related products
- Overview of 75 available MST1R gene related products
- Recommended
- pCMV6-Entry
- pCMV6-XL4
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- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pRFP-C-RS
- pGFP-V-RS
- pGFP-C-shLenti
- pCMV6-Entry
- pCMV6-XL4
- pCMV6-XL5
- pcDNA3.1+C-(K)-DYK
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pRFP-C-RS
- pGFP-V-RS
- pGFP-C-shLenti
- genomics-online: gRNA clones - Search results for 75 available MST1R gene related products
- Overview of 75 available MST1R gene related products
- Recommended
- pCMV6-Entry
- pCMV6-XL4
- pCMV6-XL5
- pcDNA3.1+C-(K)-DYK
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pRFP-C-RS
- pGFP-V-RS
- pGFP-C-shLenti
- pCMV6-Entry
- pCMV6-XL4
- pCMV6-XL5
- pcDNA3.1+C-(K)-DYK
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pRFP-C-RS
- pGFP-V-RS
- pGFP-C-shLenti
- genomics-online: primer clones - Search results for 75 available MST1R gene related products
- Overview of 75 available MST1R gene related products
- Recommended
- pCMV6-Entry
- pCMV6-XL4
- pCMV6-XL5
- pcDNA3.1+C-(K)-DYK
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pRFP-C-RS
- pGFP-V-RS
- pGFP-C-shLenti
- pCMV6-Entry
- pCMV6-XL4
- pCMV6-XL5
- pcDNA3.1+C-(K)-DYK
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pRFP-C-RS
- pGFP-V-RS
- pGFP-C-shLenti
- genomics-online: shRNA clones - Search results for 75 available MST1R gene related products
- Overview of 75 available MST1R gene related products
- Recommended
- pCMV6-Entry
- pCMV6-XL4
- pCMV6-XL5
- pcDNA3.1+C-(K)-DYK
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pRFP-C-RS
- pGFP-V-RS
- pGFP-C-shLenti
- pCMV6-Entry
- pCMV6-XL4
- pCMV6-XL5
- pcDNA3.1+C-(K)-DYK
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pRFP-C-RS
- pGFP-V-RS
- pGFP-C-shLenti
Sources for MST1R Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
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