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Aliases for MST1L Gene

Aliases for MST1L Gene

  • Macrophage Stimulating 1 Like 2 3 5
  • Macrophage Stimulating 1 (Hepatocyte Growth Factor-Like) Pseudogene 9 2 3
  • Macrophage Stimulating, Pseudogene 7 2 3
  • Macrophage Stimulating, Pseudogene 9 2 3
  • D1F15S1A 3 4
  • MST1P9 3 4
  • BRF-1 3 4
  • MSTP9 3 4
  • Putative Macrophage Stimulating 1-Like Protein 3
  • Putative Macrophage-Stimulating Protein MSTP9 3
  • Hepatocyte Growth Factor-Like Protein Homolog 4
  • Brain-Rescue-Factor-1 3
  • Brain Rescue Factor 1 4
  • MSPL-7 3
  • MSPL7 3
  • MSTP7 3

External Ids for MST1L Gene

Previous HGNC Symbols for MST1L Gene

  • MSTP7
  • MSTP9
  • MST1P9

Previous GeneCards Identifiers for MST1L Gene

  • GC01M017083

Summaries for MST1L Gene

GeneCards Summary for MST1L Gene

MST1L (Macrophage Stimulating 1 Like) is a Protein Coding gene. GO annotations related to this gene include serine-type endopeptidase activity.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MST1L Gene

Genomics for MST1L Gene

Regulatory Elements for MST1L Gene

Enhancers for MST1L Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01F016960 1.2 Ensembl ENCODE 19.3 -190.8 -190807 1.5 CREB3L1 ARID4B SIN3A DMAP1 ZNF48 ZNF121 ZNF143 FOS ZNF263 SP3 FAM231A MST1L LOC100421279 RNU1-1 ENSG00000236648 LOC105376805 CROCC SPATA21 PIR50545 PIR44310
GH01F016677 1.3 Ensembl ENCODE 16.1 +92.1 92143 1.0 ARNT MLX ARID4B SIN3A ZNF2 FOS KLF13 SP3 KAT8 SSRP1 ENSG00000237938 MST1L TRE-TTC3-1 SPEN MFAP2 ESPNP ENSG00000224621 RPS16P1 RCC2 CROCC
GH01F016676 1.1 Ensembl ENCODE 15.9 +93.2 93218 0.8 SAP130 ZNF384 ZNF316 SCRT2 ADNP EED FOS ZNF600 ZNF652 GATAD2A MST1L TRE-TTC3-1 FAM231A GC01M016679
GH01F016696 1.7 FANTOM5 Ensembl ENCODE 6.7 +69.9 69908 7.7 HDGF PKNOX1 ARNT CREB3L1 MLX ARID4B SIN3A FEZF1 ZNF2 YY1 MFAP2 ENSG00000237938 LINC01772 RPS16P1 ZBTB17 RPL22P3 ENSG00000224621 MST1L ESPNP TRE-TTC3-1
GH01F016706 1.3 Ensembl ENCODE 6.1 +63.0 63022 2.2 ATF1 ZNF133 SIN3A GLI4 ZNF48 ZNF2 ZNF121 GLIS2 ZNF416 KLF7 LINC01772 SPEN MST1L ESPNP CROCCP4 ENSG00000279151
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MST1L on UCSC Golden Path with GeneCards custom track

Genomic Location for MST1L Gene

16,754,634 bp from pter
16,770,237 bp from pter
15,604 bases
Minus strand

Genomic View for MST1L Gene

Genes around MST1L on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MST1L Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MST1L Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MST1L Gene

Proteins for MST1L Gene

  • Protein details for MST1L Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Putative macrophage stimulating 1-like protein
    Protein Accession:
    Secondary Accessions:
    • B7WPB1
    • Q13209

    Protein attributes for MST1L Gene

    715 amino acids
    Molecular mass:
    79694 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAC35412.1; Type=Miscellaneous discrepancy; Note=Unlikely isoform. Aberrant splice sites.; Evidence={ECO:0000305};

    Alternative splice isoforms for MST1L Gene


neXtProt entry for MST1L Gene

Post-translational modifications for MST1L Gene

No Post-translational modifications

Other Protein References for MST1L Gene

REFSEQ proteins:

No data available for DME Specific Peptides for MST1L Gene

Domains & Families for MST1L Gene

Suggested Antigen Peptide Sequences for MST1L Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 4 kringle domains.
  • Belongs to the peptidase S1 family. Plasminogen subfamily.
  • Contains 4 kringle domains.
  • Contains 1 PAN domain.
  • Contains 1 peptidase S1 domain.
  • Belongs to the peptidase S1 family. Plasminogen subfamily.
genes like me logo Genes that share domains with MST1L: view

No data available for Gene Families for MST1L Gene

Function for MST1L Gene

Molecular function for MST1L Gene

GENATLAS Biochemistry:
macrocyte stimulating factor 1,like sequence

Gene Ontology (GO) - Molecular Function for MST1L Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004252 serine-type endopeptidase activity IEA --
genes like me logo Genes that share ontologies with MST1L: view

Animal Model Products

Clone Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MST1L Gene

Localization for MST1L Gene

Subcellular locations from UniProtKB/Swiss-Prot for MST1L Gene


Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MST1L gene
Compartment Confidence
extracellular 4
plasma membrane 1
mitochondrion 1
peroxisome 1
nucleus 1
cytosol 1

Gene Ontology (GO) - Cellular Components for MST1L Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region IEA --
genes like me logo Genes that share ontologies with MST1L: view

Pathways & Interactions for MST1L Gene

SuperPathways for MST1L Gene

No Data Available

Interacting Proteins for MST1L Gene

Selected Interacting proteins: Q2TV78-MST1L_HUMAN for MST1L Gene via IID

Gene Ontology (GO) - Biological Process for MST1L Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006508 proteolysis IEA --
genes like me logo Genes that share ontologies with MST1L: view

No data available for Pathways by source and SIGNOR curated interactions for MST1L Gene

Transcripts for MST1L Gene

mRNA/cDNA for MST1L Gene

(1) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(5) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for MST1L Gene

Macrophage stimulating 1-like:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for MST1L Gene

No ASD Table

Relevant External Links for MST1L Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MST1L Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MST1L Gene

mRNA differential expression in normal tissues according to GTEx for MST1L Gene

This gene is overexpressed in Liver (x15.0), Kidney - Cortex (x9.7), and Pancreas (x6.9).

Protein differential expression in normal tissues from HIPED for MST1L Gene

This gene is overexpressed in Serum (61.1) and Islet of Langerhans (7.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for MST1L Gene

Protein tissue co-expression partners for MST1L Gene

NURSA nuclear receptor signaling pathways regulating expression of MST1L Gene:


SOURCE GeneReport for Unigene cluster for MST1L Gene:

genes like me logo Genes that share expression patterns with MST1L: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for MST1L Gene

Orthologs for MST1L Gene

Evolution for MST1L Gene

Gene Tree for MST1L (if available)
Gene Tree for MST1L (if available)

No data available for Orthologs for MST1L Gene

Paralogs for MST1L Gene

(24) SIMAP similar genes for MST1L Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with MST1L: view

No data available for Paralogs for MST1L Gene

Variants for MST1L Gene

Sequence variations from dbSNP and Humsavar for MST1L Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs10159208 -- 16,757,073(+) TTACT(A/G)TTTAC utr-variant-3-prime
rs1033403 -- 16,756,480(+) GACAA(A/G)TAATT utr-variant-3-prime
rs1033404 -- 16,756,487(+) AATTT(A/G)TTTCT utr-variant-3-prime
rs1055045 -- 16,765,475(-) CGGCC(C/G)ACGCA upstream-variant-2KB
rs1057286 -- 16,759,557(-) ATCCC(A/G)CATCA reference, missense

Structural Variations from Database of Genomic Variants (DGV) for MST1L Gene

Variant ID Type Subtype PubMed ID
nsv954849 CNV duplication 24416366
nsv945799 CNV duplication 23825009
nsv945798 CNV duplication 23825009
nsv9324 CNV gain+loss 18304495
nsv829625 CNV gain 20364138
nsv821743 CNV gain 20364138
nsv821511 CNV duplication 20802225
nsv7173 OTHER inversion 18451855
nsv545667 CNV loss 21841781
nsv437206 CNV loss 16327808
nsv436652 OTHER inversion 17901297
nsv428421 CNV gain+loss 18775914
nsv3965 CNV insertion 18451855
nsv1161259 CNV duplication 26073780
nsv1161242 CNV duplication 26073780
nsv1145756 CNV duplication 26484159
nsv1116446 OTHER inversion 24896259
nsv1115339 CNV duplication 24896259
nsv1075777 CNV duplication 25765185
nsv1013011 CNV gain 25217958
nsv1009050 CNV loss 25217958
nsv1004978 CNV gain+loss 25217958
esv3892414 CNV gain 25118596
esv3577752 CNV loss 25503493
esv3430695 CNV duplication 20981092
esv3414600 CNV duplication 20981092
esv33965 CNV gain+loss 17666407
esv3372391 CNV duplication 20981092
esv29948 CNV loss 18421352
esv29642 CNV gain+loss 19812545
esv2758925 CNV gain+loss 17122850
dgv93n100 CNV gain 25217958
dgv92n100 CNV gain 25217958
dgv91n100 CNV gain+loss 25217958
dgv90n100 CNV gain 25217958
dgv89n100 CNV gain+loss 25217958
dgv87n100 CNV loss 25217958
dgv86n100 CNV gain 25217958
dgv85n100 CNV gain 25217958
dgv83n100 CNV loss 25217958
dgv82n100 CNV gain+loss 25217958
dgv78n100 CNV loss 25217958
dgv77n100 CNV loss 25217958
dgv75n100 CNV gain 25217958
dgv74n100 CNV gain 25217958
dgv70n100 CNV gain+loss 25217958
dgv65n100 CNV gain 25217958
dgv63n100 CNV gain 25217958
dgv62n100 CNV gain 25217958
dgv55n100 CNV gain+loss 25217958
dgv54n100 CNV gain 25217958
dgv53n100 CNV loss 25217958
dgv52n100 CNV gain+loss 25217958
dgv52e59 CNV duplication 20981092
dgv51n100 CNV loss 25217958
dgv45n100 CNV gain 25217958
dgv42n100 CNV loss 25217958
dgv39n100 CNV gain 25217958
dgv22n67 CNV gain 20364138
dgv21n67 CNV gain 20364138
dgv20n67 CNV gain 20364138
dgv1e203 CNV gain+loss 21179565
dgv164n54 CNV loss 21841781
dgv101n100 CNV gain 25217958

Relevant External Links for MST1L Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MST1L Gene

Disorders for MST1L Gene

Relevant External Links for MST1L

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MST1L Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MST1L Gene

Publications for MST1L Gene

  1. Structure of the human D1F15S1A locus: a chromosome 1 locus with 97 percent identity to the chromosome 3 gene coding for hepatocyte growth factor-like protein. (PMID: 10728827) Degen S.J. … Carritt B. (DNA Seq. 1998) 2 3 4 64
  2. Identification of minimal eukaryotic introns through GeneBase, a user-friendly tool for parsing the NCBI Gene databank. (PMID: 26581719) Piovesan A. … Pelleri M.C. (DNA Res. 2015) 3 64
  3. The GENCODE pseudogene resource. (PMID: 22951037) Pei B. … Gerstein M.B. (Genome Biol. 2012) 3 64
  4. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 4 64
  5. Multiple MSP pseudogenes in a local repeat cluster on 1p36.2: An expanding genomic graveyard? (PMID: 10585770) van der Drift P. … Versteeg R. (Genomics 1999) 3 64

Products for MST1L Gene

Sources for MST1L Gene

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