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Aliases for MSS51 Gene

Aliases for MSS51 Gene

  • MSS51 Mitochondrial Translational Activator 2 3 5
  • Zinc Finger MYND Domain-Containing Protein 17 3 4
  • Zinc Finger, MYND-Type Containing 17 2 3
  • ZMYND17 3 4
  • MSS51 Mitochondrial Translational Activator Homolog (S. Cerevisiae) 2
  • MSS51 Mitochondrial Translational Activator Homolog 3
  • Zinc Finger, MYND Domain Containing 17 3

External Ids for MSS51 Gene

Previous HGNC Symbols for MSS51 Gene

  • ZMYND17

Previous GeneCards Identifiers for MSS51 Gene

  • GC10M075184

Summaries for MSS51 Gene

GeneCards Summary for MSS51 Gene

MSS51 (MSS51 Mitochondrial Translational Activator) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MSS51 Gene

Genomics for MSS51 Gene

Regulatory Elements for MSS51 Gene

Enhancers for MSS51 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around MSS51 on UCSC Golden Path with GeneCards custom track

Genomic Location for MSS51 Gene

73,423,579 bp from pter
73,433,561 bp from pter
9,983 bases
Minus strand

Genomic View for MSS51 Gene

Genes around MSS51 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MSS51 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MSS51 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MSS51 Gene

Proteins for MSS51 Gene

  • Protein details for MSS51 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Putative protein MSS51 homolog, mitochondrial
    Protein Accession:
    Secondary Accessions:
    • A6NGH6
    • Q2VP95
    • Q5F2H5
    • Q7Z3M9
    • Q8N8G0

    Protein attributes for MSS51 Gene

    460 amino acids
    Molecular mass:
    51289 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for MSS51 Gene


neXtProt entry for MSS51 Gene

Proteomics data for MSS51 Gene at MOPED

Post-translational modifications for MSS51 Gene

No Post-translational modifications

Other Protein References for MSS51 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for MSS51 Gene

Domains & Families for MSS51 Gene

Gene Families for MSS51 Gene

Protein Domains for MSS51 Gene


Suggested Antigen Peptide Sequences for MSS51 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 MYND-type zinc finger.
  • Contains 1 MYND-type zinc finger.
genes like me logo Genes that share domains with MSS51: view

Function for MSS51 Gene

Phenotypes for MSS51 Gene

genes like me logo Genes that share phenotypes with MSS51: view

Animal Model Products

miRNA for MSS51 Gene

miRTarBase miRNAs that target MSS51

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for MSS51 Gene

Localization for MSS51 Gene

Subcellular locations from

Jensen Localization Image for MSS51 Gene COMPARTMENTS Subcellular localization image for MSS51 gene
Compartment Confidence
mitochondrion 3
nucleus 3
cytosol 1
extracellular 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for MSS51 Gene

Pathways & Interactions for MSS51 Gene

SuperPathways for MSS51 Gene

No Data Available

Interacting Proteins for MSS51 Gene

Gene Ontology (GO) - Biological Process for MSS51 Gene


No data available for Pathways by source and SIGNOR curated interactions for MSS51 Gene

Drugs & Compounds for MSS51 Gene

No Compound Related Data Available

Transcripts for MSS51 Gene

mRNA/cDNA for MSS51 Gene

(1) REFSEQ mRNAs :
(5) Additional mRNA sequences :
(18) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for MSS51 Gene

MSS51 mitochondrial translational activator:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for MSS51 Gene

No ASD Table

Relevant External Links for MSS51 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MSS51 Gene

mRNA expression in normal human tissues for MSS51 Gene

mRNA differential expression in normal tissues according to GTEx for MSS51 Gene

This gene is overexpressed in Muscle - Skeletal (x18.4).

SOURCE GeneReport for Unigene cluster for MSS51 Gene Hs.631823

genes like me logo Genes that share expression patterns with MSS51: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MSS51 Gene

Orthologs for MSS51 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MSS51 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia ZMYND17 35
  • 87.67 (n)
  • 84.9 (a)
MSS51 36
  • 84 (a)
(Canis familiaris)
Mammalia MSS51 35
  • 88.26 (n)
  • 85.43 (a)
MSS51 36
  • 78 (a)
(Mus musculus)
Mammalia Mss51 35
  • 84.35 (n)
  • 79.68 (a)
Mss51 16
Mss51 36
  • 79 (a)
(Pan troglodytes)
Mammalia ZMYND17 35
  • 99.2 (n)
  • 98.91 (a)
MSS51 36
  • 99 (a)
(Rattus norvegicus)
Mammalia Mss51 35
  • 81.65 (n)
  • 76.97 (a)
(Ornithorhynchus anatinus)
Mammalia MSS51 36
  • 56 (a)
(Gallus gallus)
Aves MSS51 35
  • 61.37 (n)
  • 58.31 (a)
MSS51 36
  • 55 (a)
(Anolis carolinensis)
Reptilia MSS51 36
  • 52 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100496751 35
  • 57.39 (n)
  • 51.13 (a)
(Danio rerio)
Actinopterygii LOC100330275 35
  • 55.26 (n)
  • 48.9 (a)
mss51 36
  • 48 (a)
Species with no ortholog for MSS51:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MSS51 Gene

Gene Tree for MSS51 (if available)
Gene Tree for MSS51 (if available)

Paralogs for MSS51 Gene

(1) SIMAP similar genes for MSS51 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with MSS51: view

No data available for Paralogs for MSS51 Gene

Variants for MSS51 Gene

Sequence variations from dbSNP and Humsavar for MSS51 Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type
rs11591720 - 73,424,686(+) GTTTG(A/G)GGGAC reference, missense
rs3209644 -- 73,423,976(+) CTTTT(A/C/G/T)TTTGT utr-variant-3-prime
rs2297452 -- 73,426,854(+) AATGA(C/G)AGCTG intron-variant
rs11817351 -- 73,431,898(+) CTTTA(A/G)GGCCC intron-variant
rs11817375 -- 73,432,023(+) CCTCA(A/G)GCAAG intron-variant

Variation tolerance for MSS51 Gene

Residual Variation Intolerance Score: 95% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.88; 74.17% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for MSS51 Gene

Disorders for MSS51 Gene

Relevant External Links for MSS51

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MSS51 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MSS51 Gene

Publications for MSS51 Gene

  1. Dual functions of Mss51 couple synthesis of Cox1 to assembly of cytochrome c oxidase in Saccharomyces cerevisiae mitochondria. (PMID: 19710419) Perez-Martinez X. … Fox T.D. (Mol. Biol. Cell 2009) 2 3 67
  2. ANXA7, PPP3CB, DNAJC9, and ZMYND17 genes at chromosome 10q22 associated with the subgroup of schizophrenia with deficits in attention and executive function. (PMID: 21531385) Liu C.M. … Hwu H.G. (Biol. Psychiatry 2011) 3
  3. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PMID: 16385451) Grupe A. … Goate A. (Am. J. Hum. Genet. 2006) 3
  4. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PMID: 15146197) Brandenberger R. … Stanton L.W. (Nat. Biotechnol. 2004) 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for MSS51 Gene

Sources for MSS51 Gene