MSS51 Gene
protein-coding GIFtS: 39
GCID: GC10M075184
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MSS51 mitochondrial translational activator(Previous names: zinc finger, MYND-type containing 17, MSS51 mitochondrial...)
(Previous symbol: ZMYND17)
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Aliases
for MSS51 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| MSS51 Mitochondrial Translational Activator1 2 | | MSS51 Mitochondrial Translational Activator Homolog (S. Cerevisiae)1 | | ZMYND171 2 3 | | MSS51 Mitochondrial Translational Activator Homolog2 | | Zinc Finger, MYND-Type Containing 171 2 | | Putative Protein MSS51 Homolog, Mitochondrial2 | | Zinc Finger MYND Domain-Containing Protein 172 3 | | Zinc Finger, MYND Domain Containing 172 | | FLJ395651 | | |
Export aliases for MSS51 gene to outside databases |
Summaries
for MSS51 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for MSS51 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000010.10 NC_018921.1 NT_030059.13
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for MSS51
Other transcription factors
Search SABiosciences Chromatin IP Primers for MSS51
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MSS51 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 10q22.2 Ensembl cytogenetic band: 10q22.2 HGNC cytogenetic band: 10q22.3MSS51 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 10 GeneLoc Exon Structure GeneLoc location for GC10M075184: view genomic region
(about GC identifiers)
Start:
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75,183,337 bp from pter |
End:
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75,193,319 bp from pter |
Size:
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9,983 bases |
Orientation:
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minus strand |
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Proteins
for MSS51 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: MSS51_HUMAN, Q4VC12 (See
protein sequence)Recommended Name: Putative protein MSS51 homolog, mitochondrial Size: 460 amino acids; 51289 Da
Caution: Although no clear MSS51 ortholog is encoded in mammalian genomes, the mammalian MSS51/ZMYND17 protein issignificantly similar. Considered by a number of resources to be the ortholog of yeast MSS51
Secondary accessions: A6NGH6 Q2VP95 Q5F2H5 Q7Z3M9 Q8N8G0Alternative splicing: 3 isoforms: Q4VC12-1 Q4VC12-2 Q4VC12-3 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for MSS51: NX_Q4VC12
MSS51 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001019764.1
ENSEMBL proteins: ENSP00000435203 ENSP00000362003 ENSP00000299432
Human Recombinant Protein Products:
MSS51 Antibody Products:
Assay Products for MSS51: |
Protein
Domains /
Families
for MSS51 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
MSS51 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q4VC12ProtoNet protein and cluster: Q4VC12 1 Blocks protein family: IPB002893 Zn-finger
UniProtKB/Swiss-Prot: MSS51_HUMAN, Q4VC12Similarity: Contains 1 MYND-type zinc finger |
Function
for MSS51 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MSS51 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MSS51
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript Custom all cDNA clones Services for MSS51 | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MSS51 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MSS51 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MSS51 |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0008270 | zinc ion binding |
IEA | -- |
MSS51 for ontologies About GeneDecksing
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Pathways & Interactions
for MSS51 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MSS51
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0035176 | social behavior |
IEP | -- |
MSS51 for ontologies About GeneDecksing
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Drugs & Compounds
for MSS51 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for MSS51
Search CenterWatch for drugs/clinical trials and news about MSS51
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Transcripts
for MSS51 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for MSS51 gene: NM_001024593.1 Unigene Cluster for MSS51: MSS51 mitochondrial translational activator Hs.631823 [show with all ESTs]Unigene Representative Sequence: BC0946933 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000487126 ENST00000372912 ENST00000299432(uc001juc.3 uc001jud.3 uc009xrg.3 uc009xrh.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MSS51 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MSS51
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript Custom all cDNA clones Services for MSS51 | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MSS51 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MSS51 |
Additional cDNA sequence: AK096884.1 AK309870.1 BC094693.1 BC109255.1 BC109256.1 3 DOTS entries: DT.40224739 DT.40309340 DT.91944045 18 AceView cDNA sequences: AA262260 AW875856 BX537678 BE622010 BE674227 AK096884 NM_178451 AW138218 BX500736 T98035 N45597 BF575350 BQ025861 CB306071 R41084 AA486810 CF552595 AA093874
GeneLoc Exon Structure
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Expression
for MSS51 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| MSS51 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GATGAGGTTG
About this image
See MSS51 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for MSS51
SOURCE GeneReport for Unigene cluster: Hs.631823
SABiosciences Custom PCR Arrays for MSS51
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MSS51
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat MSS51 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MSS51 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MSS51 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MSS51 |
Orthologs
for MSS51 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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This gene was present in the common ancestor of chordates.
Orthologs for MSS51 gene from 4/9 species (see all 9) About this table
ENSEMBL Gene Tree for MSS51 (if available)
TreeFam Gene Tree for MSS51 (if available) |
Paralogs
for MSS51 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for MSS51 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 10 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for MSS51 (75183337 - 75193319 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for MSS51: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MSS51 |
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Disorders
/ Diseases
for MSS51 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
MSS51 for disorders About GeneDecksing
OMIM gene information: 614773
OMIM disorders: --
2  diseases for MSS51: About MalaCardsalzheimer's disease schizophrenia
Export disorders for MSS51 gene to outside databases
|
Publications
for MSS51 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for MSS51 gene integrated from 9 sources:
(articles sorted by number of sources associating them with MSS51) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Dual functions of Mss51 couple synthesis of Cox1 to a ssembly of cytochrome c oxidase in Saccharomyces cerevisiae mitochondria. (PubMed id 19710419)1, 3 Perez-Martinez X....Fox T.D. (2009)
- ANXA7, PPP3CB, DNAJC9, and ZMYND17 genes at chromosom e 10q22 associated with the subgroup of schizophrenia with deficits in attentio n and executive function. (PubMed id 21531385)1 Liu C.M....Hwu H.G. (2011)
- The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
- A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PubMed id 16385451)1 Grupe A....Goate A. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
- The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)2 Deloukas P.... Rogers J. (2004)
- Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PubMed id 15146197)1 Brandenberger R.... Stanton L.W. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
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External Searches for MSS51 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing MSS51 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing MSS51 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing MSS51 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for MSS51 | Pharmacogenomics, SNPs, Pathways |
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| | |
About This Section
| Patent Information for MSS51 gene:
Search GeneIP for patents involving MSS51
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for MSS51 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for MSS51 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MSS51 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MSS51 | | | OriGene Protein Over-expression Lysate for MSS51 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for MSS51 | | OriGene 3'-UTR Clone for MSS51 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MSS51 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MSS51 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for MSS51 | | OriGene Custom Protein Services for MSS51 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat MSS51 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MSS51 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MSS51 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MSS51 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MSS51 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MSS51 |
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 |  |  |  | |
| | | | Search Tocris compounds for MSS51 |
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 | | | MSS51 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MSS51 |
|  |  |  | | | | Search ThermoFisher Antibodies for MSS51 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MSS51 |
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