MSRB1 Gene
protein-coding GIFtS: 46
GCID: GC16M001997
|
|
methionine sulfoxide reductase B1(Previous names: selenoprotein X, 1 )
(Previous symbol: SEPX1)
| |
Aliases
for MSRB1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Methionine Sulfoxide Reductase B11 2 | | SELR2 | | SEPX11 2 3 5 | | Methionine-R-Sulfoxide Reductase B12 | | SepR1 2 | | Selenoprotein R2 | | Selenoprotein X, 11 2 | | EC 1.8.4.-3 | | SelX1 3 | | MsrB13 | | SELX2 5 | | Selenoprotein X3 | | SelR1 | | |
Export aliases for MSRB1 gene to outside databasesPrevious GC identifer: GC16M001995 |
Summaries
for MSRB1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for MSRB1:
This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteineis encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have acommon stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Seccodon rather than as a stop signal. This protein belongs to the methionine sulfoxide reductase (Msr) protein familywhich includes repair enzymes that reduce oxidized methionine residues in proteins. The protein encoded by this geneis expressed in a variety of adult and fetal tissues and localizes to the cell nucleus and cytosol. (provided byRefSeq, Mar 2012)
Gene Wiki entry for MSRB1 (SEPX1)
|
Genomic Views
for MSRB1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000016.9 NC_018927.1 NT_010393.16
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for MSRB1
Other transcription factors
Search SABiosciences Chromatin IP Primers for MSRB1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MSRB1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 16p13.3 Ensembl cytogenetic band: 16p13.3 HGNC cytogenetic band: 16p13.3MSRB1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 16 GeneLoc Exon Structure GeneLoc location for GC16M001997: view genomic region
(about GC identifiers)
Start:
|
1,988,211 bp from pter |
End:
|
1,993,327 bp from pter |
Size:
|
5,117 bases |
Orientation:
|
minus strand |
|
Proteins
for MSRB1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: MSRB1_HUMAN, Q9NZV6 (See
protein sequence)Recommended Name: Methionine-R-sulfoxide reductase B1 Size: 116 amino acids; 12760 Da
Cofactor: Binds 1 zinc ion per subunit (By similarity)
Subcellular location: Cytoplasm (By similarity). Nucleus (By similarity)
Sequence caution: Sequence=AAF28948.1; Type=Erroneous termination; Positions=95; Note=Translated as Sec;
1 PDB 3D structure from  and Proteopedia  for MSRB1:3MAO (3D)
Secondary accessions: Q96RX6 Q9BTV2 Q9P0B1Explore the universe of human proteins at neXtProt for MSRB1: NX_Q9NZV6
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9NZV6
MSRB1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_057416.1
ENSEMBL proteins: ENSP00000355084 ENSP00000457320 ENSP00000382657 ENSP00000456557
Human Recombinant Protein Products for MSRB1:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
MSRB1 for ontologies About GeneDecksing
MSRB1 Antibody Products:
Assay Products for MSRB1: |
Protein
Domains /
Families
for MSRB1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
MSRB1 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9NZV6ProtoNet protein and cluster: Q9NZV6 1 Blocks protein family: IPB002579 Protein of unknown function DUF25
UniProtKB/Swiss-Prot: MSRB1_HUMAN, Q9NZV6Similarity: Belongs to the MsrB Met sulfoxide reductase family |
Function
for MSRB1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: MSRB1_HUMAN, Q9NZV6Catalytic activity: L-methionine + oxidized thioredoxin = L-methionine R-oxide + reduced thioredoxin Enzyme Number (IUBMB): EC 1.8.4.-1
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0008113 | peptide-methionine (S)-S-oxide reductase activity |
-- | -- | | GO:0008270 | zinc ion binding |
ISS | 14699060 | | GO:0033743 | peptide-methionine (R)-S-oxide reductase activity |
IEA | -- | | GO:0070191 | methionine-R-sulfoxide reductase activity |
IEA | -- |
MSRB1 for ontologies About GeneDecksing
Phenotypes:
2 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Msrb1):
MSRB1 for phenotypes About GeneDecksing
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MSRB1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MSRB1
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript Custom all cDNA clones Services for MSRB1 | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MSRB1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MSRB1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MSRB1 |
|
Pathways & Interactions
for MSRB1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Selenium Metabolism and Selenoproteins | | | 2 | Selenium Pathway | |
2  BioSystems Pathways for MSRB1
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MSRB1
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table
MSRB1 for ontologies About GeneDecksing
|
Drugs & Compounds
for MSRB1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
MSRB1 for compounds About GeneDecksing
 Browse Tocris compounds for MSRB1
10/12 Novoseek chemical compound relationships for MSRB1 gene (see all 12) About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| methionine sulfoxide |
98.6 |
125 |
19373970 (3), 17418992 (3), 16735467 (2), 18302927 (2) (see all 78) |
| methionine |
82.6 |
28 |
17180746 (1), 18302927 (1), 19406207 (1), 16542431 (1) (see all 22) |
| sulfoxide |
78.2 |
5 |
18302927 (1), 17938273 (1), 15680231 (1), 15280355 (1) |
| selenocysteine |
69.4 |
6 |
16262444 (1), 14699060 (1) |
| cysteine |
48.4 |
2 |
16262444 (1), 14580313 (1) |
| oxygen |
44 |
5 |
15680219 (1), 14699060 (1), 16684363 (1), 11084287 (1) (see all 5) |
| h2o2 |
36.3 |
1 |
18206120 (1) |
| selenium |
36.1 |
1 |
15210302 (1) |
| cholesterol |
0 |
1 |
16497665 (1) |
| calcium |
0 |
2 |
11010965 (1), 19902913 (1) |
Search CenterWatch for drugs/clinical trials and news about MSRB1
|
Transcripts
for MSRB1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for MSRB1 gene: NM_016332.2 Unigene Cluster for MSRB1: Methionine sulfoxide reductase B1 Hs.655346 [show with all ESTs]Unigene Representative Sequence: BM5487975 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000361871(uc021tam.1) ENST00000473663 ENST00000399753 ENST00000564908
ENST00000489198
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MSRB1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MSRB1
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript Custom all cDNA clones Services for MSRB1 | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MSRB1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MSRB1 |
Additional cDNA sequence: AF161388.1 AF166124.1 AF187272.1 AK026128.1 BC003127.1 13 DOTS entries: DT.455004 DT.100812561 DT.100812559 DT.120704502 DT.95286963 DT.100705114 DT.100812564 DT.40115486 DT.86841265 DT.91749933 DT.99928998 DT.92433855 DT.99985022 24 AceView cDNA sequences: CR598886 NM_016332 CR616027 AK026128 BC003127 AF166124 CR614779 CR609793 AF187272 CR590497 BX396802 AF161388 BX397284 AV653651 AI348922 BX449117 AA829291 CB148054 AW900908 BF360519 BG315397 BF901731 BG166852 AW856109
GeneLoc Exon Structure
4 Alternative Splicing Database (ASD) splice patterns (SP) for MSRB1 About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 | ^ | 6a | · | 6b | · | 6c |
|---|
|
| SP1: | | | | | | | - | | | | | | - | | | | | | | | | | |
| SP2: | | | | | | | - | | | | - | | - | | | | | | | | | | |
| SP3: | | | | | | | - | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for MSRB1
|
Expression
for MSRB1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| MSRB1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CTCGGAGGCC
About this image
See MSRB1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for MSRB1
SOURCE GeneReport for Unigene cluster: Hs.655346
SABiosciences Custom PCR Arrays for MSRB1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MSRB1
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat MSRB1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MSRB1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MSRB1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MSRB1 |
Orthologs
for MSRB1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the last universal common ancestor (LUCA).
Orthologs for MSRB1 gene from 9/31 species (see all 31) About this table
ENSEMBL Gene Tree for MSRB1 (if available)
TreeFam Gene Tree for MSRB1 (if available) |
Paralogs
for MSRB1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for MSRB1 gene
2 SIMAP similar genes for MSRB1 using alignment to 4 protein entries: MSRB1_HUMAN (see all proteins):SEPX1 MSRB3
MSRB1 for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for MSRB1
PGOHUM00000259330
|
Genomic Variants
for MSRB1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 16 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for MSRB1 (1988211 - 1993327 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for MSRB1: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MSRB1 |
|
Disorders
/ Diseases
for MSRB1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
MSRB1 for disorders About GeneDecksing
OMIM gene information: 606216
OMIM disorders: --
13  diseases for MSRB1: About MalaCardsischemia chronic lymphocytic leukemia mycobacterium tuberculosis alzheimer's disease
cholesterol cataract parkinson's disease lymphocytic leukemia
twinning schizophrenia pneumonia tuberculosis
leukemia
2 Novoseek disease relationships for MSRB1 gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| ischemia |
0 |
2 |
16677789 (1), 15680220 (1) |
| inflammation |
0 |
1 |
15680220 (1) |
Export disorders for MSRB1 gene to outside databases
|
Publications
for MSRB1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for MSRB1 gene, integrated from 9 sources (see all 97):
(articles sorted by number of sources associating them with MSRB1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Novel selenoproteins identified in silico and in vivo by using a conserved RNA structural motif. (PubMed id 10608886)1, 2, 3 Lescure A.... Krol A. (1999)
- Diversity of protein and mRNA forms of mammalian methi onine sulfoxide reductase B1 due to intronization and protein processing. (PubMed id 20634897)1, 3 Liang X....Gladyshev V.N. (2010)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16. (PubMed id 11157797)1, 2 Daniels R.J....Higgs D.R. (2001)
- Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)1, 2 Zhang Q.-H.... Chen Z. (2000)
- Methionine sulfoxide reduction in mammals: characterization of methionine-R-sulfoxide reductases. (PubMed id 14699060)1, 9 Kim H.-Y. and Gladyshev V.N. (2004)
- Up-regulation of ADM and SEPX1 in the lymphoblastoid cells of patients in monozygotic twins discordant for schizophrenia. (PubMed id 18081029)1, 9 Kakiuchi C....Kato T. (2008)
- Neutrophil granulocytes uniquely express, among human blood cells, high levels of Methionine-sulfoxide-reductase enzymes. (PubMed id 17938273)1, 9 Achilli C....Minetti G. (2008)
- Involvement of MsrB1 in the regulation of redox balanc e and inhibition of peroxynitrite-induced apoptosis in human lens epithelial cel ls. (PubMed id 22713178)1 Jia Y....Huang K. (2012)
- Single nucleotide polymorphisms of matrix metalloprot einase 9 (MMP-9) and tumour protein 73 (TP73) interact with Epstein Barr virus in chronic lymphocytic leukemia: results from the European case-control study E piLymph. (PubMed id 21048031)1 Casabonne D....de Sanjose S. (2010)
|
External Searches for MSRB1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing MSRB1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing MSRB1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing MSRB1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for MSRB1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for MSRB1 gene:
Search GeneIP for patents involving MSRB1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for MSRB1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for MSRB1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MSRB1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MSRB1 | | | OriGene Protein Over-expression Lysate for MSRB1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for MSRB1 | | OriGene 3'-UTR Clone for MSRB1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MSRB1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MSRB1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for MSRB1 | | OriGene Custom Protein Services for MSRB1 | | | OriGene Custom Immunoassay Development | | |
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 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat MSRB1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MSRB1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MSRB1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MSRB1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MSRB1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MSRB1 |
| |
 |  |  |  | |
| | | | Search Tocris compounds for MSRB1 |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | MSRB1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MSRB1 |
|  |  |  |  | | | | ThermoFisher Antibodies for MSRB1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MSRB1 |
| |  | |
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