Aliases for MSMO1 Gene
External Ids for MSMO1 Gene
Previous HGNC Symbols for MSMO1 Gene
Previous GeneCards Identifiers for MSMO1 Gene
Sterol-C4-mehtyl oxidase-like protein was isolated based on its similarity to the yeast ERG25 protein. It contains a set of putative metal binding motifs with similarity to that seen in a family of membrane desaturases-hydroxylases. The protein is localized to the endoplasmic reticulum membrane and is believed to function in cholesterol biosynthesis. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
GeneCards Summary for MSMO1 Gene
MSMO1 (Methylsterol Monooxygenase 1) is a Protein Coding gene. Diseases associated with MSMO1 include Microcephaly, Congenital Cataract, And Psoriasiform Dermatitis and Msmo1-Related Psoriasiform Dermatitis. Among its related pathways are cholesterol biosynthesis I and Terpenoid backbone biosynthesis. GO annotations related to this gene include oxidoreductase activity and C-4 methylsterol oxidase activity. An important paralog of this gene is FAXDC2.
UniProtKB/Swiss-Prot for MSMO1 Gene
Catalyzes the first step in the removal of the two C-4 methyl groups of 4,4-dimethylzymosterol.