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MSMB Gene

protein-coding GIFtS: 62

GC10P051219

microseminoprotein, beta-
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
HPC13 ^², ⁵
IGBF ^¹, ², ³
MSP ^¹, ²
MSPB ^¹, ²
OTTHUMP00000019596 ^²
OTTHUMP00000019597 ^²
PN44 ^¹, ², ³
PRPS ^¹, ²
PRSP ^³
PSP ^¹, ²
PSP-94 ^¹, ², ³
PSP57 ^¹, ²
PSP94 ^¹, ²
beta-microseminoprotein ^²

Descriptions
Immunoglobulin-binding factor ^³
Prostate secreted seminal plasma protein ^², ³
Prostate secretory protein PSP94 ^³
Seminal plasma beta-inhibin ^², ³
immunoglobulin binding factor ^²
microseminoprotein, beta- ^²
prostatic secretory protein 94 ^²

External Ids
HGNC: 7372¹
Entrez Gene: 4477²
UniProtKB: P08118³
Ensembl: ENSG00000138294⁷

Search outside databases for aliases for MSMB gene

Previous GC identifers: GC10P050393 GC10P051441 GC10P050894

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for MSMB:

The protein encoded by this gene is a member of the immunoglobulin binding factor family. It is

synthesized by the epithelial cells of the prostate gland and secreted into the seminal plasma.

This protein has inhibin-like activity. It may have a role as an autocrine paracrine factor in

uterine, breast and other female reproductive tissues. The expression of the encoded protein is

found to be decreased in prostate cancer. Two alternatively spliced transcript variants encoding

different isoforms are described for this gene. The use of alternate polyadenylation sites has

been found for this gene. [provided by RefSeq]

Gene Wiki entry for MSMB

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the MSMB gene

Entrez Gene cytogenetic band: 10q11.2 Ensembl cytogenetic band: 10q11.23 HGNC cytogenetic band: 10q11.2

MSMB Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 10 GeneLoc Exon Structure

GeneLoc location for GC10P051219: (about GC identifiers)

Start:	51,219,559 bp from pter
End:	51,232,601 bp from pter
Size:	13,043 bases
Orientation:	plus strand

RefSeq DNA sequence:

NC_000010.9 NT_008583.16

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: MSMB_HUMAN, P08118 (See protein sequence)

Recommended Name: Beta-microseminoprotein precursor

Size: 114 amino acids; 12865 Da

Subunit: Interacts with PI16

Subcellular location: Secreted. Note=Sperm surface

Miscellaneous: Specific receptors for this protein are found on spermatozoa and in the prostate

Caution: Was originally thought to inhibit the secretion of FSH by pituitary cells

PDB structures from and Proteopedia :

2IZ3 (3D)

Secondary accessions: B1API6 P11999 Q13125 Q6IAY9 Q9UC59

Alternative splicing: 2 isoforms: P08118-1 P08118-2

REFSEQ proteins (2 alternative transcripts):

NP_002434.1 NP_619540.1

ENSEMBL proteins:

ENSP00000351363 ENSP00000298239

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Sigma-Aldrich Proteins for MSMB
	R&D Systems Recombinant & Natural Proteins for MSMB (PSP94)
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (Prostate Secretory Protein/PSP)
	Human Recombinant Proteins from Abnova (MSMB)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

3 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005576	extracellular region	IEA	--
GO:0005615	extracellular space	TAS	7566962
GO:0005634	nucleus	TAS	7566962

About this table

Antibodies for MSMB:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for MSMB
	R&D Systems Antibodies for MSMB (PSP94)
	Antibodies from Abcam (Prostate Secretory Protein/PSP), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (MSMB)
	Novus Biologicals Antibodies for MSMB

Assays for MSMB:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry P08118

ProtoNet protein and cluster: P08118

1 Blocks protein family: IPB008735 Beta-microseminoprotein

UniProtKB/Swiss-Prot: MSMB_HUMAN, P08118

Similarity: Belongs to the beta-microseminoprotein family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (MSMB)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (MSMB)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_138634

Applied Biosystems Silencer® siRNAs for MSMB

Sigma-Aldrich siRNA for MSMB

Sigma-Aldrich shRNA for MSMB

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for MSMB
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_002443
Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_002443
untagged cDNA clones in CMV expression vector (see all 2): NM_002443

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_002443

Genatlas biochemistry entry for MSMB:

microseminoprotein beta,14kDa,synthesized by prostate epithelial cells,secreted in to the seminal

fluid

4 MGI mutant phenotypes (inferred from 3 alleles) (MGI details for Msmb):

endocrine/exocrine gland

immune system

reproductive system

tumorigenesis

1 Gene Ontology (GO) molecular function term (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003674	molecular_function	ND	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Gene Network Central^TM Interacting Genes and Proteins Network for MSMB

5/25 Interacting proteins for MSMB (ENSP00000351363³) via UniProtKB, MINT, and/or STRING (see all 25 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
PRB4	ENSP00000240636³	STRING (score=.708) STRING (score=.705)
PI16	ENSP00000362778³	STRING (score=.968)
PRPS1	ENSP00000361512³	STRING (score=.947)
CRISP3	ENSP00000263045³	STRING (score=.942)
PRPS2	ENSP00000370043³	STRING (score=.941)

About this table

1 Gene Ontology (GO) biological process term (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0008150	biological_process	ND	--

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for MSMB
6 Novoseek chemical compound relationships for MSMB gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
pck-3145	87.61	2	16331603 (1), 16197609 (1)
fructose	8.92	1	9629442 (1)
hydroxyapatite	8.56	2	7983258 (1), 1347286 (1)
steroid	0.00	1	10412042 (1)
calcium	0.00	3	11312269 (2), 16495573 (1)
tyrosine	0.00	1	10049818 (1)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (MSMB)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (MSMB)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_138634

Sigma-Aldrich siRNA for MSMB

Sigma-Aldrich shRNA for MSMB

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_002443 NM_138634

REFSEQ mRNAs for MSMB gene (2 alternative transcripts):

NM_002443.2 NM_138634.1

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_002443 NM_138634

               OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_002443
                                 Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_002443
                                 untagged cDNA clones in CMV expression vector (see all 2): NM_002443

Additional cDNA sequence:

AK312108.1 BC005257.1 BT006816.1 CR457015.1 M15885.1 S67815.1 U22178.1 U78976.1

19 DOTS entries:

DT.95376322 DT.100037349 DT.91768534 DT.95376324 DT.91768532 DT.121281503 DT.121281879 DT.121281564

DT.95376325 DT.121281781 DT.95376316 DT.87001710 DT.75118122 DT.121281877 DT.432060 DT.95376321

DT.121281754 DT.92395591 DT.96086444

24/562 AceView cDNA sequences (see all 562 ):

BF965280 BM768852 BE672898 AI829244 AI420347 AA807843 AA548400 AA588630

BX641403 AI420876 AI298524 AA687632 BF445307 AA541642 AA588853 NM_002443

AI817297 AA369901 BM768859 AA661727 AI658868 BM768648 AA662090 CA313444

highest scoring ESTs for MSMB:

AA532495 AA176984 AA177023 AA216404 AA224934 AA225025 AA225143 AA225152 AA225409 AA225880

Unigene Cluster for MSMB:

Microseminoprotein, beta-

Hs.255462 [show with all ESTs]

Unigene Representative Sequence: BF965172

GeneLoc Exon Structure

5/7 Alternative Splicing Database (ASD) splice patterns (SP) for MSMB (see all 7 )

ExUns:	1a	·	1b	^	2	^	3	^	4a	·	4b	^	5a	·	5b	·	5c	·	5d
SP1:					-						-		-
SP2:
SP3:											-		-
SP4:					-
SP5:					-				-		-		-

About this scheme

ECgene alternative splicing isoforms for MSMB

2 Ensembl transcripts including schematic representations:

ENST00000358559 ENST00000298239

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

MSMB expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for MSMB

¹ / ² / ³

5 probe-sets matching MSMB gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
32149_at²^{, 3}	U95-A	1	1.00	1.00	1.00	1.00	AA532495	1.00	1.00	1.00	1
210297_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	U22178	0.80	1.00	0.91	1
207430_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_002443	0.60	1.00	0.82	1
210297_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
207430_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

GeneDecks MSMB for binary patterns associated with the probe-sets selected above

About GeneDecksing

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: CCTATCAGTA

SOURCE GeneReport for Unigene cluster: Hs.255462
Expression variation in blood from EXPOLDB for MSMB
UniProtKB/Swiss-Prot: MSMB_HUMAN, P08118
Tissue specificity: Strongly expressed in prostate, liver, kidney, breast and penis. Also expressed
in pancreas, esophagus, stomach, deodenum, colon, trachea, lung, salivary glands and fallopian
tube. PSP94 is expressed in lung and breast, whereas PSP57 is found in kidney and bladder

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for MSMB gene from 5 species

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
chimpanzee (Pan troglodytes)	MSMB¹	--	microseminoprotein, beta-	99.12(n) 98.23(a)	747280 XM_001156501.1 XP_001156501.1
cow (Bos taurus)	MSMB¹	--	microseminoprotein, beta-	70.87(n) 54.05(a)	616019 XM_867982.2 XP_873075.1
rat (Rattus norvegicus)	Msmb¹	--	microseminoprotein, beta	62.24(n) 46.02(a)	29311 NM_019188.1 NP_062061.1
mouse (Mus musculus)	Msmb^{1, 5}	14⁵	beta-microseminoprotein^{1, 5}	58.26(n)¹ 44.14(a)¹	17695¹ NM_020597.2¹ NP_065622.1¹ AF033264⁵ AF033265⁵ (see all 11)
chicken (Gallus gallus)	MSMB¹	--	microseminoprotein, beta-	53.69(n) 42.48(a)	423773 XM_421645.1 XP_421645.1

About this table Species with no ortholog for MSMB

ENSEMBL Gene Tree for MSMB

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/122 NCBI SNPs in MSMB are shown (see all 122 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 53)

AB	SNP ID	Valid	Chr 10 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs10993994^1,2	A,C,F,H	51219502(+)	`AATGAT/CGTCGA`	2	--	ng5¹		4		EU EA WA	410
	rs4935176^1,2	A,C,F,H	51219551(+)	`GCTTTT/GCCTGG`	2	--	ng5¹ ese³		6		NA EA WA	432
	rs1804464^1,2	C	51232353(+)	`TCGTGG/TTGGAG`	2	W/C V/L	mis¹		0	--	--	--	--
--	rs12358352^1,2	H	51232337(+)	`GAGGAC/TTGCAA`	2	D/D T/I	syn¹ mis¹ ese³		4		EU EA WA	406
--	rs3208433^1,2	F	51232414(+)	`TGCTTC/TTAGTA`	2	--	ut3¹ ese³		1		MN	184
	rs1802774^1,2	C	51232300(+)	`TTATGA/CCAAAG`	2	T/P D/A	mis¹		4		EU EA WA	420
--	rs11812658^1,2	C	51218843(+)	`CCCTAG/TGAGGT`	2	--	ng5¹		0	--	--	--	--
	rs7904463^1,2	A,C,F,H	51229475(+)	`CTCACC/TTCCTT`	2	--	int¹		11		EU EA WA NA	966
	rs10821610^1,2	A,C,F,H	51220951(+)	`GCTGCA/GGAGCT`	2	--	int¹		3		EU EA	300
	rs7076948^1,2	A,C,F,H	51228131(+)	`AGAAAT/CAGCAG`	2	--	int¹		4		EU EA WA	418

About this table

HapMap Linkage Disequilibrium images for MSMB (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 157145 disorders: 611928

UniProtKB/Swiss-Prot: MSMB_HUMAN, P08118

A genetic variation in MSMB is associated with susceptibility to hereditary prostate

cancer type 13 (HPC13) [MIM:611928]

10/20 Novoseek disease relationships for MSMB gene (see all 20 )

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
familial creutzfeldt-jakob disease	65.64	2	8643624 (1)
prion diseases	63.27	3	10953401 (1), 8643624 (1)
prostate cancer	62.49	47	10581002 (4), 9973097 (4), 17237810 (4), 7509484 (3) (see all 25)
prostatic adenocarcinoma	60.03	4	15674347 (1), 16809150 (1), 9817377 (1), 9537594 (1)
prostatic intraepithelial neoplasia	58.18	1	16278416 (1)
prostate carcinoma	35.21	5	7688168 (3), 10477906 (1), 9136076 (1)
creutzfeldt-jakob disease	31.75	1	18160847 (1)
benign prostatic hyperplasia	25.65	4	7688168 (2), 7509484 (1), 8939292 (1)
premalignant	11.43	1	10477906 (1)
bronchoalveolar lavage fluid	8.51	2	8520786 (1), 10612294 (1)

About this table

Human Gene Mutation Database: MSMB
Human Genome Epidemiology Navigator: MSMB (8 documents)

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/138 PubMed articles for MSMB gene (see all 138 ):

Alternative splicing of PSP94 (prostatic secretory protein of 94 amino acids) mRNA in prostate tissue. (PubMed id 7566962)^{1, 3, 4} Xuan J.W....Clarke M.W. (1995)
Solution structures of human and porcine beta-microseminoprotein. (PubMed id 16930619)^{1, 3, 4} Ghasriani H.... Drakenberg T. (2006)
Identification, purification and characterization of a novel human blood protein with binding affinity for prostate secretory protein of 94 amino acids. (PubMed id 15344909)^{1, 3, 4} Reeves J.R.... Tanner J.E. (2005)
Structural identity of immunoglobulin binding factor and prostatic secretory protein of human seminal plasma. (PubMed id 1930232)^{1, 3, 4} Liang Z.G.... Koide S.S. (1991)
Cloning and nucleotide sequence analysis of the human beta- microseminoprotein gene. (PubMed id 2322265)^{1, 3, 4} Green C.B.... Kwok S.C.M. (1990)
Decreased expression of prostatic secretory protein PSP94 in prostate cancer. (PubMed id 7506990)^{1, 3, 4} Liu A.Y.... Vessella R.L. (1993)
Assignment of the human gene for beta-microseminoprotein (MSMB) to chromosome 10 and demonstration of related genes in other vertebrates. (PubMed id 1783399)^{1, 2, 3} Ulvsback M....Lundwall A. (1991)
Multiple loci identified in a genome-wide association study of prostate cancer. (PubMed id 18264096)^{3, 4} Thomas G....Chanock S.J. (2008)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
Newly identified proteins in human nasal lavage fluid from non- smokers and smokers using two-dimensional gel electrophoresis and peptide mass fingerprinting. (PubMed id 11788998)^{3, 4} Ghafouri B.... Lindahl M. (2002)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 4477	HGNC: 7372	AceView: MSMB	Ensembl:ENSG00000138294	euGenes: HUgn4477
ECgene: MSMB	H-InvDB: MSMB

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
ATLAS Chromosomes in Cancer entry for MSMB	Genetics and Cytogenetics in Oncology and Haematology

Licensable Technologies for MSMB
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for MSMB:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for MSMB-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for MSMB		Antibodies for MSMB
	Explore super-pooled esiRNAs		Proteins for MSMB
	Lentivirus-delivered shRNAs for MSMB		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (MSMB)
	Antibodies (MSMB)
	Chimera RNAi (MSMB)
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

Search for Antibodies & Assays

	Recombinant Proteins (Prostate Secretory Protein/PSP)
	Antibodies (Prostate Secretory Protein/PSP)

Search OriGene for MSMB

Search Tocris compounds for MSMB

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for MSMB

GeneCards Homepage - Last full update: 1 Jul 2009 Incremental update: 13 Oct 2009

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MSMB Gene

protein-coding GIFtS: 62

Aliases &
Descriptions
for MSMB

Summaries
for MSMB

Genomic Location
for MSMB

Proteins
for MSMB

Protein Domains/
Families
for MSMB

Gene Function
for MSMB

Pathways & Interactions
for MSMB

Drugs & Compounds
for MSMB

Transcripts
for MSMB

Expression
for MSMB

Orthologs
for MSMB

Paralogs
for MSMB

SNPs/Variants
for MSMB

Disorders & Mutations
for MSMB

Medical News
for MSMB

Publications
for MSMB

Search for MSMB

Genome Databases showing MSMB

Other Databases showing MSMB

Specialized Databases showing MSMB

Licensable Technologies
for MSMB

Services
for MSMB

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

MSMB (Gene Symbol)
HPC13
IGBF
MSP
MSPB
OTTHUMP00000019596
OTTHUMP00000019597
PN44
PRPS
PRSP
PSP
PSP-94
PSP57
PSP94
beta-microseminoprotein
Immunoglobulin-binding factor
Prostate secreted seminal plasma protein
Prostate secretory protein PSP94
Seminal plasma beta-inhibin
immunoglobulin binding factor
microseminoprotein, beta-
prostatic secretory protein 94

MSMB Gene

protein-coding GIFtS: 62

Aliases & Descriptionsfor MSMB

Summariesfor MSMB

Genomic Locationfor MSMB

Proteinsfor MSMB

Protein Domains/Familiesfor MSMB

Gene Functionfor MSMB

Pathways & Interactionsfor MSMB

Drugs & Compoundsfor MSMB

Transcriptsfor MSMB

Expression for MSMB

Orthologsfor MSMB

Paralogsfor MSMB

SNPs/Variantsfor MSMB

Disorders & Mutationsfor MSMB

Medical Newsfor MSMB

Publicationsfor MSMB

Search for MSMB

Genome Databases showing MSMB

Other Databases showing MSMB

Specialized Databases showing MSMB

Licensable Technologiesfor MSMB

Servicesfor MSMB

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for MSMB

Summaries
for MSMB

Genomic Location
for MSMB

Proteins
for MSMB

Protein Domains/
Families
for MSMB

Gene Function
for MSMB

Pathways & Interactions
for MSMB

Drugs & Compounds
for MSMB

Transcripts
for MSMB

Expression
for MSMB

Orthologs
for MSMB

Paralogs
for MSMB

SNPs/Variants
for MSMB

Disorders & Mutations
for MSMB

Medical News
for MSMB

Publications
for MSMB

Licensable Technologies
for MSMB

Services
for MSMB