 |
 | Services
| |
 |
Aliases &
Descriptions
for MSH6
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase)
About This Section
|
| Aliases |
|---|
| GTBP 2, 3, 5 | | GTMBP 3 | | HNPCC5 2, 5 | | HSAP 2 | | p160 3 |
| | | Descriptions |
|---|
| G/T mismatch-binding protein 2, 3 | | MutS-alpha 160 kDa subunit 3 | | mutS (E. coli) homolog 6 1 | | mutS homolog 6 2 | | mutS homolog 6 (E. coli) 2 | | sperm-associated protein 2 |
|
| |
Search outside databases for aliases for MSH6 genePrevious GC identifers: GC02P048026 GC02P048179 GC02P047984 |
Summaries
for MSH6(According to Entrez Gene,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| EntrezGene summary for MSH6:
This gene encodes a protein similar to the MutS protein. In E. coli, the MutS protein helps in the
recognition of mismatched nucleotides, prior to their repair. A highly conserved region of
approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS
homologs. The encoded protein of this gene combines with MSH2 to form a mismatch recognition
complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA
mismatches are bound and dissociated. Mutations in this gene have been identified in individuals
with hereditary nonpolyposis colon cancer (HNPCC) and endometrial cancer. [provided by RefSeq]
UniProtKB/Swiss-Prot: MSH6_HUMAN, P52701Function: Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with
MSH2 to form MutS alpha, which binds to DNA mismatches thereby initiating DNA repair. When bound,
MutS alpha bends the DNA helix and shields approximately 20 base pairs, and recognizes single base
mismatches and dinucleotide insertion-deletion loops (IDL) in the DNA. After mismatch binding,
forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for
directing the downstream MMR events, including strand discrimination, excision, and resynthesis.
ATP binding and hydrolysis play a pivotal role in mismatch repair functions. The ATPase activity
associated with MutS alpha regulates binding similar to a molecular switch: mismatched DNA
provokes ADP-->ATP exchange, resulting in a discernible conformational transition that converts
MutS alpha into a sliding clamp capable of hydrolysis-independent diffusion along the DNA
backbone. This transition is crucial for mismatch repair. MutS alpha may also play a role in DNA
homologous recombination repairGene Wiki entry for MSH6 |
Genomic Location
for MSH6
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to
UCSC and
Ensembl,
Transcription factor binding sites according to
SABiosciences)
About This Section
| Genomic View: UCSC Golden Path with GeneCards custom track
 Transcription factor binding sites upstream to the MSH6 gene 
Entrez Gene cytogenetic band: 2p16 Ensembl cytogenetic band: 2p16.3 HGNC cytogenetic band: 2p16MSH6 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc gene densities for chromosome 2 GeneLoc Exon Structure GeneLoc location for GC02P047921:
(about GC identifiers)
Start:
|
47,863,725 bp from pter |
End:
|
47,887,596 bp from pter |
Size:
|
23,872 bases |
Orientation:
|
plus strand |
RefSeq DNA sequence:- NC_000002.10 NT_022184.14
| Proteins
for MSH6
(According to
1UniProtKB,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Enzo Life Sciences,
Abnova,
OriGene and/or,
Abcam,
Biochemical Assays by
Invitrogen,
Millipore,
R&D Systems,
Cell Signaling Technology, and/or
Enzo Life Sciences,
Ontologies according to Gene
Ontology Consortium 01 Apr 2009 and
Entrez Gene,
Antibodies by Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Cell Signaling Technology,
Abcam,
Abnova, and/or
Novus Biologicals)
About This Section
| UniProtKB/Swiss-Prot: MSH6_HUMAN, P52701 (See
protein sequence)Recommended Name: DNA mismatch repair protein Msh6 Size: 1360 amino acids; 152786 Da
Subunit: Heterodimer consisting of MSH2-MSH6 (MutS alpha). Forms a ternary complex with MutL alpha
(MLH1-PMS1). Interacts with EXO1. Part of the BRCA1-associated genome surveillance complex (BASC),
which contains BRCA1, MSH2, MSH6, MLH1, ATM, BLM, PMS2 and the RAD50-MRE11-NBS1 protein complex.
This association could be a dynamic process changing throughout the cell cycle and within
subnuclear domains. Interacts with ATR
Subcellular location: Nucleus
PDB structures from  and Proteopedia  :2GFU (3D)
2O8B (3D)
2O8C (3D)
2O8D (3D)
2O8E (3D)
2O8F (3D)
Secondary accessions: O43706 O43917 Q8TCX4 Q9BTB5Alternative splicing: 2 isoforms: P52701-1 P52701-2 Post-translational modifications:
The N-terminus is blocked1
Phosphorylated upon DNA damage, probably by ATM or ATR1
Phosphorylated by PRKCZ, which may prevent MutS alpha degradation by the ubiquitin-proteasome
pathway1
View phosphorylation sites using PhosphoSite2
REFSEQ proteins: NP_000170.1
ENSEMBL proteins: ENSP00000234420
Human Recombinant Proteins  Browse Origene for full length recombinant human proteins expressed in human HEK293 cells
3 Gene Ontology (GO) cellular component terms (links to tree view): About this table
Antibodies for MSH6:
Assays for MSH6: | Protein
Domains/
Families
for MSH6(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| - Graphical View of Domain Structure for InterPro Entry P52701
ProtoNet protein and cluster: P52701 3 Blocks protein families: IPB000313 PWWP domain IPB007695 DNA mismatch repair protein MutS IPB007696 MutS III
UniProtKB/Swiss-Prot: MSH6_HUMAN, P52701Similarity: Belongs to the DNA mismatch repair mutS familySimilarity: Contains 1 PWWP domain | Gene Function
for MSH6
(According to MGI Jun 06 2009, UniProtKB,
IUBMB,and/or Genatlas,
shRNA from
OriGene,
Sigma-Aldrich, RNAi from
Sigma-Aldrich,
RNAi Products,
Clones, and
Q-PCR Products
from Invitrogen,
Millipore,
OriGene, and/or
Abnova,
siRNAs from
Applied Biosystems,
SYBR primers from OriGene,
Cell-based Assays from Millipore,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
| OriGene 29mer shRNA kit in GFP-retroviral vector: NM_000179
 Applied Biosystems Silencer® siRNAs for MSH6
 Sigma-Aldrich siRNA and siRNA Panels for MSH6
Sigma-Aldrich shRNA for MSH6
Explore Sigma-Aldrich super-pooled esiRNAs
OriGene GFP tagged cDNA clone in CMV expression vector: NM_000179
Myc/DDK tagged cDNA clone in CMV expression vector: NM_000179
untagged cDNA clones in CMV expression vector (see all 2): NM_000179
Primers:  Browse
Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
OriGene genome-wide validated SYBR primer pairs: NM_000179
UniProtKB/Swiss-Prot: MSH6_HUMAN, P52701Function: Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with
MSH2 to form MutS alpha, which binds to DNA mismatches thereby initiating DNA repair. When bound,
MutS alpha bends the DNA helix and shields approximately 20 base pairs, and recognizes single base
mismatches and dinucleotide insertion-deletion loops (IDL) in the DNA. After mismatch binding,
forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for
directing the downstream MMR events, including strand discrimination, excision, and resynthesis.
ATP binding and hydrolysis play a pivotal role in mismatch repair functions. The ATPase activity
associated with MutS alpha regulates binding similar to a molecular switch: mismatched DNA
provokes ADP-->ATP exchange, resulting in a discernible conformational transition that converts
MutS alpha into a sliding clamp capable of hydrolysis-independent diffusion along the DNA
backbone. This transition is crucial for mismatch repair. MutS alpha may also play a role in DNA
homologous recombination repairGenatlas biochemistry entry for MSH6:must S (E coli) homolog 6,GT binding protein,complexing with MSH2 in mismatch repair (MUTS alpha
heterodimer),functioning as a molecular switch between ADP and ATP bound forms,selective for
repair or GT mispair and single deplaced bases,with two alternatively spliced
isoforms,GTBPN,mutated in gastric carcinomas in association with microsatellite mutator phenotype
(MMP),deleted in sporadic colorectal cancer (early onset)2 MGI mutant phenotypes (inferred from 3 alleles ) (MGI details for Msh6):
5/17 Gene Ontology (GO) molecular function terms (links to tree view) (see all 17
): About this table | Pathways & Interactions
for MSH6
(Pathways according to Invitrogen
(maps by GeneGo),
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Proteins Network according to
SABiosciences,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|
1 Sigma-Aldrich "Your Favorite Gene" Pathway for MSH6 (Your Favorite Gene powered by Ingenuity)
Gene Network CentralTM Interacting Genes and Proteins Network for MSH6
5/57 Interacting proteins for MSH6 (P527011, 2 ENSP000002344203) via UniProtKB, MINT, and/or STRING (see all 57
)About this table
5/11 Gene Ontology (GO) biological process terms (links to tree view) (see all 11
): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0000710 | meiotic mismatch repair |
ISS | -- | | GO:0006974 | response to DNA damage stimulus |
IEA | -- | | GO:0008340 | determination of adult life span |
IEA | -- | | GO:0008630 | DNA damage response, signal transduction resulting in induction of apoptosis |
IEA | -- | | GO:0009411 | response to UV |
IEA | -- |
About this table
|
Drugs & Compounds
for MSH6(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
 Browse Tocris compounds for MSH6
6  Novoseek chemical compound relationships for MSH6 gene
About this table
|
Transcripts
for MSH6(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from Invitrogen,
Millipore, and/or
Abnova,
siRNAs from Applied Biosystems,
Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
Tagged/untagged cDNA clones from
OriGene,
Expression Assays from Applied Biosystems)
About This Section
| OriGene 29mer shRNA kit in GFP-retroviral vector: NM_000179
Sigma-Aldrich siRNA and siRNA Panels for MSH6
Sigma-Aldrich shRNA for MSH6
Explore Sigma-Aldrich super-pooled esiRNAs
Applied Biosystems Silencer® siRNAs: NM_000179 REFSEQ mRNAs for MSH6 gene: NM_000179.2
Applied Biosystems TaqMan ® Gene Expression Assays: NM_000179
OriGene GFP tagged cDNA clone in CMV expression vector: NM_000179
Myc/DDK tagged cDNA clone in CMV expression vector: NM_000179
untagged cDNA clones in CMV expression vector (see all 2): NM_000179
Additional cDNA sequence: AK130683.1 AK293921.1 AK304735.1 AK308392.1 BC004246.1 BC071594.1 BC104665.1 D89646.1 U28946.1 U54777.2 16 DOTS entries: DT.101958448 DT.91759465 DT.419083 DT.100798420 DT.109348 DT.95214649 DT.95229340 DT.450978 DT.95229311 DT.102836851 DT.92005749 DT.120935256 DT.40106377 DT.40133304 DT.95229350 DT.97860065 24/282 AceView cDNA sequences (see all 282
):AA830138 AA226977 CB127844 AI016113 AW452697 BQ059465 BC040724 BQ772835 AI433156 CB160008 BQ012468 AI341470 AA025294 BC004246 CB122519 BX100831 BG393107 AA321991 AA811388 BM797714 BG535053 BM785404 AW248497 AI148344
 highest scoring ESTs for MSH6:U28946 AA024534 AA025294 AA160060 AA171937 AA226977 AA470117 AA480652 AA768743 AA811388 Unigene Cluster for MSH6: MutS homolog 6 (E. coli) Hs.445052 [show with all ESTs]Unigene Representative Sequence: NM_000179
GeneLoc Exon Structure
5/9 Alternative Splicing Database (ASD) splice patterns (SP) for MSH6 (see all 9
)
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | · | 1e | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7 | ^ | 8a | · | 8b | · | 8c | · | 8d | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 |
|---|
|
| SP1: | | | | | | | | | | | - | | - | | - | | - | | | | | | | | | | | | | | - | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | - | | - | | - | | - | | | | | | - | | | | | | | | - | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | - | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | |
About this scheme
ECgene alternative splicing isoforms for MSH6
1 Ensembl transcript including schematic representation: ENST00000234420
|
Expression
for MSH6
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 219 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Expression Assays from
Applied Biosystems
)
About This Section
| MSH6 expression in normal and diseased human tissues
Applied Biosystems TaqMan ® Gene Expression Assays for MSH6
1 / 2 / 3 12 probe-sets matching MSH6 gene Data from
(Publications) and GNF BioGPS
About these images
About these images
CGAP SAGE TAG: --
SOURCE GeneReport for Unigene cluster: Hs.445052
Expression variation in blood from EXPOLDB for MSH6 |
Orthologs
for MSH6
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Jun 06 2009,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for MSH6 gene from 5/21 species (see all 21
)
About this table Species with no ortholog for MSH6
ENSEMBL Gene Tree for MSH6 | Paralogs
for MSH6(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
| Paralogs for MSH6 gene
- MSH32
|
SNPs/Variants
for MSH6(According to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Genotyping Reagents from
Applied Biosystems)
About This Section
|
HapMap Linkage Disequilibrium images for MSH6 (up to first 250kb)
|
Disorders & Mutations
for MSH6
(in which this Gene is Involved, According to
OMIM, UniProtKB,
Novoseek, PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
HGMD, GAD,
HuGE Navigator,
BCGD,
and/or TGDB.)
About This Section
|
OMIM: 600678 UniProtKB/Swiss-Prot: MSH6_HUMAN, P52701
Defects in MSH6 are the cause of hereditary non-polyposis colorectal cancer type 5
(HNPCC5) [MIM:600678]. Mutations in more than one gene locus can be involved alone or in
combination in the production of the HNPCC phenotype (also called Lynch syndrome). Most families
with clinically recognized HNPCC have mutations in either MLH1 or MSH2 genes. HNPCC is an
autosomal, dominantly inherited disease associated with marked increase in cancer susceptibility.
It is characterized by a familial predisposition to early onset colorectal carcinoma (CRC) and
extra-colonic cancers of the gastrointestinal, urological and female reproductive tracts. HNPCC is
reported to be the most common form of inherited colorectal cancer in the Western world. Cancers
in HNPCC originate within benign neoplastic polyps termed adenomas. Clinically, HNPCC is often
divided into two subgroups. Type I: hereditary predisposition to colorectal cancer, a young age of
onset, and carcinoma observed in the proximal colon. Type II: patients have an increased risk for
cancers in certain tissues such as the uterus, ovary, breast, stomach, small intestine, skin, and
larynx in addition to the colon. Diagnosis of classical HNPCC is based on the Amsterdam criteria:
3 or more relatives affected by colorectal cancer, one a first degree relative of the other two; 2
or more generation affected; 1 or more colorectal cancers presenting before 50 years of age;
exclusion of hereditary polyposis syndromes. MSH6 mutations appear to be associated with atypical
HNPCC and in particular with development of endometrial carcinoma or atypical endometrial
hyperplasia, the presumed precursor of endometrial cancer. Defects in MSH6 are also found in
familial colorectal cancers (suspected or incomplete HNPCC) that do not fulfill the Amsterdam
criteria for HNPCC Defects in MSH6 are a cause of susceptibility to endometrial cancer [MIM:608089]10/42 Novoseek disease relationships for MSH6 gene (see all 42
)
| Disease |
Score |
Articles |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| lynch syndrome |
94.92 |
20 |
18625694 (3), 10404064 (1), 18030674 (1), 17453009 (1) (see all 16) |
| microsatellite instability |
94.35 |
43 |
17117178 (3), 12019211 (1), 16203774 (1), 16879751 (1) (see all 37) |
| colorectal cancer |
87.54 |
196 |
11333868 (5), 18067074 (5), 17117178 (4), 18269114 (4) (see all 91) |
| hereditary nonpolyposis colon cancer |
83.95 |
2 |
16237223 (1), 15184898 (1) |
| endometrial cancer |
83.21 |
26 |
15805151 (3), 18269114 (3), 14961575 (2), 14760069 (1) (see all 19) |
| germ-line mutation |
74.58 |
17 |
18331697 (3), 11245474 (3), 15872200 (2), 16885385 (2) (see all 10) |
| muir-torre syndrome |
73.22 |
1 |
18270343 (1) |
| colorectal carcinoma |
66.90 |
4 |
10965560 (1), 14871813 (1), 15613860 (1), 10537275 (1) |
| colorectal tumors |
63.96 |
1 |
9674699 (1) |
| turcot syndrome |
63.28 |
2 |
16000562 (2) |
About this table
GeneTests: MSH6
Hereditary Non-Polyposis Colon Cancer
Human Gene Mutation Database: MSH6
Genetic Association Database: MSH6
Human Genome Epidemiology Navigator: MSH6 (68 documents)
|
Medical News
for MSH6(Possibly Related Articles in
Doctor's Guide)
About This Section
| |
Publications
for MSH6 (in
PubMed.
Associations of this gene to articles via
1Novoseek,
2HGNC,
3Entrez Gene,
4UniProtKB/Swiss-Prot,
5UniProtKB/TrEMBL,
6GAD, and/or
7PharmGKB)
About This Section
| 10/391 PubMed articles for MSH6 gene (see all 391
):- Mutation analysis of the MLH1, MSH2 and MSH6 genes in patients with double primary cancers of the colorectum and the endometrium: a population-based study in northern Sweden. (PubMed id 14961575)1, 3, 4, 6 Cederquist K.... Groenberg H. (2004)
- MSH6 germline mutations are rare in colorectal cancer families. (PubMed id 14520694)1, 3, 4, 6 Peterlongo P....Ellis N.A. (2003)
- Mutations of GTBP in genetically unstable cells. (PubMed id 7604266)1, 2, 3, 4 Papadopoulos N.... Vogelstein B. (1995)
- Molecular and clinical characteristics of MSH6 variants: an analysis of 25 index carriers of a germline variant. (PubMed id 11709755)1, 3, 4 Berends M.J....Kleibeuker J.H. (2002)
- Association of hereditary nonpolyposis colorectal cancer-related tumors displaying low microsatellite instability with MSH6 germline mutations. (PubMed id 10521294)1, 3, 4 Wu Y....Hofstra R.M.W. (1999)
- The role of MLH1, MSH2 and MSH6 in the development of multiple colorectal cancers. (PubMed id 16106253)1, 3, 6 Lawes D.A....Boulos P.B. (2005)
- Eight novel MSH6 germline mutations in patients with familial and nonfamilial colorectal cancer selected by loss of protein expression in tumor tissue. (PubMed id 14974087)1, 3, 4 Plaschke J....Schackert H.K. (2004)
- No MSH6 germline mutations in breast cancer families with colorectal and/or endometrial cancer. (PubMed id 15805151)1, 3, 6 Vahteristo P....Nevanlinna H. (2005)
- Germ-line msh6 mutations in colorectal cancer families. (PubMed id 10537275)1, 3, 4 Kolodner R.D.... Li F.P. (1999)
- GTBP, a 160-kilodalton protein essential for mismatch-binding activity in human cells. (PubMed id 7604265)1, 3, 4 Palombo F.... Jiricny J. (1995)
|
Search for MSH6
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing MSH6
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
and/or
H-InvDB)
About This Section
|
| Other Databases showing MSH6
(According to HUGE)
About This Section
| -- |
Specialized Databases showing MSH6(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| ATLAS Chromosomes in Cancer entry for MSH6 | Genetics and Cytogenetics in Oncology and Haematology | | GeneReviews | http://www.genetests.org/query?gene=MSH6 | | Hereditary non-polyposis colorectal cancer db | http://www.nfdht.nl/ | | NIEHS-SNPs | http://egp.gs.washington.edu/data/msh6/ |
|
| | | About This Section
| --
| Services
for MSH6(Reagents available from Applied Biosystems, Antibodies and assays by Cell
Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section
| 
Products for MSH6:
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