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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

MSBP1 Gene

protein-coding   GIFtS: 11
GCID: GC00U990213

Minisatellite Binding Protein 1

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Minisatellite Binding Protein 11 2

External Ids:    HGNC: 73181   Entrez Gene: 44312   

Export aliases for MSBP1 gene to outside databases


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for MSBP1 Gene: 
MSBP1 (minisatellite binding protein 1) is a protein-coding gene. Diseases associated with MSBP1 include fasting hypoglycemia, and west nile virus.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for MSBP1
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Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MSBP1


Genomic Location:
Chromosome:--   

       


(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB: --


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section
  --

(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
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Animal Models:
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(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
About This Section



Interactions:

    Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MSBP1

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
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MSBP1 for compounds           About GeneDecksing

Browse Small Molecules at EMD Millipore
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Browse Tocris compounds for MSBP1

10/15 Novoseek inferred chemical compound relationships for MSBP1 gene (see all 15)    About this table
Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
sterol 88 106 16940799 (7), 18460914 (4), 16603153 (2), 9062340 (2) (see all 72)
fatty acid 59.7 15 16603153 (2), 18460914 (2), 11114831 (1), 15930175 (1) (see all 13)
25-hydroxycholesterol 58.6 1 7744865 (1)
lipid 45.2 18 16210374 (1), 17854140 (1), 10750688 (1), 11090277 (1) (see all 14)
rapamycin 39.5 2 14970836 (1)
cholesterol 36.6 11 12580245 (1), 19230619 (1), 16958674 (1), 9478955 (1) (see all 9)
triacylglycerol 28.2 1 19230619 (1)
3-hydroxy-3-methylglutaryl-coa 27.5 1 7759101 (1)
glucose 17.8 6 10459565 (1), 9350590 (1), 18519448 (1), 7476297 (1) (see all 5)
ethanol 3.42 2 20069651 (1), 16481976 (1)

Search CenterWatch for drugs/clinical trials and news about MSBP1

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

miRNA
Products:
     
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Search QIAGEN for miScript miRNA Assays for microRNAs that regulate MSBP1
Browse SwitchGear 3'UTR luciferase reporter plasmids
Inhib. RNA
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(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
See probesets specificity/sensitivity at GeneAnnot
CGAP TAG: --

    SABiosciences Custom PCR Arrays for MSBP1
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In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MSBP1

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section
  --

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
  --

(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
SABiosciences Cancer Mutation PCR Assays
Search QIAGEN SeqTarget long-range PCR primers for resequencing MSBP1
DNA2.0 Custom Variant and Variant Library Synthesis for MSBP1

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section
20/33 diseases for MSBP1 (see all 33):    About MalaCards
fasting hypoglycemia    west nile virus    idiopathic pulmonary fibrosis    essential hypertension
ovarian disease    insulin resistance    pulmonary fibrosis    lipodystrophy
liposarcoma    prostate adenocarcinoma    hypoglycemia    nasopharyngitis
hypoxia    hypertension    hepatitis c    hepatitis b
diabetes mellitus    hepatitis    pancreatic cancer    obesity


MSBP1 for disorders           About GeneDecksing

10/13 Novoseek inferred disease relationships for MSBP1 gene (see all 13)    About this table

Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
insulin resistance 45.3 5 9663927 (3)
intrauterine growth retardation 4.02 1 8949569 (1)
breast cancer 1.66 4 9376191 (1), 18490442 (1), 8951618 (1), 7518340 (1)
malnutrition 0 1 16391585 (1)
essential hypertension 0 1 9350590 (1)
necrosis 0 2 9478955 (1), 8605587 (1)
shock 0 2 12177805 (1), 10946852 (1)
ovarian carcinoma 0 2 11376559 (2)
ovarian cancer 0 1 11376559 (1)
hepatitis 0 1 11509148 (1)


Export disorders for MSBP1 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
About This Section

PubMed articles for MSBP1 gene, integrated from 9 sources (see all 174):
(articles sorted by number of sources associating them with MSBP1)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Minisatellite binding protein Msbp-1 is a sequence-specific single-stranded DNA-binding protein. (PubMed id 1754375)1, 3 Collick A....Jeffreys A.J. (1991)
  2. Clustering of hypervariable minisatellites in the proterminal regions of human autosomes. (PubMed id 3243550)1, 3 Royle N.J....Jeffreys A.J. (1988)
  3. Nelfinavir induces liposarcoma apoptosis and cell cyc le arrest by upregulating sterol regulatory element binding protein-1. (PubMed id 16940799)9 Chow W.A....Valdes-Albini F. (2006)
  4. Tissue availability of insulin-like growth factor I is inversely related to insulin resistance in essential hypertension: effects of angiotensin converting enzyme inhibition. (PubMed id 9663927)9 Laviades C....Diez J. (1998)
  5. Is the tissue availability of circulating insulin-like growth factor I involved in organ damage and glucose regulation in hypertension? (PubMed id 9350590)9 Laviades C....Diez J. (1997)
  6. N-3 polyunsaturated fatty acid regulation of hepatic gene transcription. (PubMed id 18460914)9 Jump D.B. (2008)
  7. Human immunodeficiency virus type 1 Tat binding protein-1 is a transcriptional coactivator specific for TR. (PubMed id 11463857)9 Ishizuka T....Mori M. (2001)
  8. The polymorphism Arg585Gln in the gene of the sterol regulatory element binding protein-1 (SREBP-1) is not a determinant of ketosis prone type 2 diabetes (KPD) in Africans. (PubMed id 19062325)9 Choukem S.P....Gautier J.F. (2009)
  9. Feedback regulation between zipcode binding protein 1 and beta-catenin mRNAs in breast cancer cells. (PubMed id 18490442)9 Gu W....Singer R.H. (2008)
  10. Sterol regulatory element binding protein 1 interacts with pregnane X receptor and constitutive androstane receptor and represses their target genes. (PubMed id 18334917)9 Roth A....Meyer U.A. (2008)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section
 ANDOR
Aliases
Disorders
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section
Entrez Gene: 4431 HGNC: 7318 euGenes: HUgn4431 ECgene: MSBP1 H-InvDB: MSBP1

(According to HUGE)
About This Section
  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
NameDescription
PharmGKB entry for MSBP1 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
About This Section
Patent Information for MSBP1 gene:
Search GeneIP for patents involving MSBP1

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
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GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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