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MSBP1 Gene

protein-coding   GIFtS: 11
GCID: GC00U990213

Minisatellite Binding Protein 1

  See MSBP1-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Minisatellite Binding Protein 11 2

External Ids:    HGNC: 73181   Entrez Gene: 44312   

Export aliases for MSBP1 gene to outside databases


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for MSBP1 Gene:
MSBP1 (minisatellite binding protein 1) is a protein-coding gene. Diseases associated with MSBP1 include west nile virus, and ovarian disease.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:
   Search for regulatory transcription factor binding sites for MSBP1
         Other transcription factors

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Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MSBP1


Genomic Location:
Chromosome:--   

       


(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB: --


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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  --

(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Animal Models:
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(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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  --

(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for MSBP1
Interactions:

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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
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  Browse compounds at ApexBio 

Browse Tocris compounds for MSBP1

Selected Novoseek inferred chemical compound relationships for MSBP1 gene (see all 15)    About this table
Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
sterol 88 106 16940799 (7), 18460914 (4), 16603153 (2), 9062340 (2) (see all 72)
fatty acid 59.7 15 16603153 (2), 18460914 (2), 11114831 (1), 15930175 (1) (see all 13)
25-hydroxycholesterol 58.6 1 7744865 (1)
lipid 45.2 18 16210374 (1), 17854140 (1), 10750688 (1), 11090277 (1) (see all 14)
rapamycin 39.5 2 14970836 (1)
cholesterol 36.6 11 12580245 (1), 19230619 (1), 16958674 (1), 9478955 (1) (see all 9)
triacylglycerol 28.2 1 19230619 (1)
3-hydroxy-3-methylglutaryl-coa 27.5 1 7759101 (1)
glucose 17.8 6 10459565 (1), 9350590 (1), 18519448 (1), 7476297 (1) (see all 5)
ethanol 3.42 2 20069651 (1), 16481976 (1)



Find genes that share compounds with MSBP1           About GenesLikeMe



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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miRNA
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(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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See probesets specificity/sensitivity at GeneAnnot
CGAP TAG: --

MSBP1 Protein expression data from MOPED1, PaxDb2 and MaxQB3 --
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In Situ
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(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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  --

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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  --

(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Site Specific Mutation Identification with PCR Assays
Search QIAGEN SeqTarget long-range PCR primers for resequencing MSBP1
DNA2.0 Custom Variant and Variant Library Synthesis for MSBP1

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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6 diseases for MSBP1:    
About MalaCards
west nile virus    ovarian disease    essential hypertension    idiopathic pulmonary fibrosis
insulin resistance    type 2 diabetes mellitus


Find genes that share disorders with MSBP1           About GenesLikeMe

Selected Novoseek inferred disease relationships for MSBP1 gene (see all 13)    About this table

Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
insulin resistance 45.3 5 9663927 (3)
intrauterine growth retardation 4.02 1 8949569 (1)
breast cancer 1.66 4 9376191 (1), 18490442 (1), 8951618 (1), 7518340 (1)
malnutrition 0 1 16391585 (1)
essential hypertension 0 1 9350590 (1)
necrosis 0 2 9478955 (1), 8605587 (1)
shock 0 2 12177805 (1), 10946852 (1)
ovarian carcinoma 0 2 11376559 (2)
ovarian cancer 0 1 11376559 (1)
hepatitis 0 1 11509148 (1)


Export disorders for MSBP1 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for MSBP1 gene, integrated from 10 sources (see all 174):
(articles sorted by number of sources associating them with MSBP1)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Minisatellite binding protein Msbp-1 is a sequence-specific single-stranded DNA-binding protein. (PubMed id 1754375)1, 3 Collick A....Jeffreys A.J. (Nucleic Acids Res. 1991)
  2. Clustering of hypervariable minisatellites in the proterminal regions of human autosomes. (PubMed id 3243550)1, 3 Royle N.J....Jeffreys A.J. (Genomics 1988)
  3. Nelfinavir induces liposarcoma apoptosis and cell cycle arrest by upregulating sterol regulatory element binding protein-1. (PubMed id 16940799)9 Chow W.A....Valdes-Albini F. (Anticancer Drugs 2006)
  4. Tissue availability of insulin-like growth factor I is inversely related to insulin resistance in essential hypertension: effects of angiotensin converting enzyme inhibition. (PubMed id 9663927)9 Laviades C....DA-ez J. (J. Hypertens. 1998)
  5. Is the tissue availability of circulating insulin-like growth factor I involved in organ damage and glucose regulation in hypertension? (PubMed id 9350590)9 Laviades C....DA-ez J. (J. Hypertens. 1997)
  6. N-3 polyunsaturated fatty acid regulation of hepatic gene transcription. (PubMed id 18460914)9 Jump D.B. (Curr. Opin. Lipidol. 2008)
  7. Human immunodeficiency virus type 1 Tat binding protein-1 is a transcriptional coactivator specific for TR. (PubMed id 11463857)9 Ishizuka T....Mori M. (Mol. Endocrinol. 2001)
  8. The polymorphism Arg585Gln in the gene of the sterol regulatory element binding protein-1 (SREBP-1) is not a determinant of ketosis prone type 2 diabetes (KPD) in Africans. (PubMed id 19062325)9 Choukem S.P....Gautier J.F. (amp 2009)
  9. Feedback regulation between zipcode binding protein 1 and beta-catenin mRNAs in breast cancer cells. (PubMed id 18490442)9 Gu W....Singer R.H. (Mol. Cell. Biol. 2008)
  10. Sterol regulatory element binding protein 1 interacts with pregnane X receptor and constitutive androstane receptor and represses their target genes. (PubMed id 18334917)9 Roth A....Meyer U.A. (Pharmacogenet. Genomics 2008)

(in PubMed, OMIM, and NCBI Bookshelf)
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 ANDOR
Aliases
Disorders
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 4431 HGNC: 7318 euGenes: HUgn4431 ECgene: MSBP1 H-InvDB: MSBP1

(According to HUGE)
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  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for MSBP1 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for MSBP1 gene:
Search GeneIP for patents involving MSBP1

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from genOway)
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