MSANTD4 Gene
protein-coding GIFtS: 40
GCID: GC11M105866
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Myb/SANT-like DNA-binding domain containing 4 with coiled-coils(Previous name: KIAA1826 )
(Previous symbol: KIAA1826)
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Aliases
for MSANTD4 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Myb/SANT-Like DNA-Binding Domain Containing 4 With Coiled-Coils1 2 3 | | KIAA18261 2 3 | | Myb/SANT-Like DNA-Binding Domain-Containing Protein 42 |
Export aliases for MSANTD4 gene to outside databases |
Summaries
for MSANTD4 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Gene Wiki entry for MSANTD4 (KIAA1826)
|
Genomic Views
for MSANTD4 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000011.9 NC_018922.1 NT_033899.8
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for MSANTD4
Other transcription factors
Search SABiosciences Chromatin IP Primers for MSANTD4
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MSANTD4 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 11q22 Ensembl cytogenetic band: 11q22.3 HGNC cytogenetic band: 11q22MSANTD4 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 11 GeneLoc Exon Structure GeneLoc location for GC11M105866: view genomic region
(about GC identifiers)
Start:
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105,866,350 bp from pter |
End:
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105,893,130 bp from pter |
Size:
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26,781 bases |
Orientation:
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minus strand |
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Proteins
for MSANTD4 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: MSD4_HUMAN, Q8NCY6 (See
protein sequence)Recommended Name: Myb/SANT-like DNA-binding domain-containing protein 4 Size: 345 amino acids; 41150 Da
Sequence caution: Sequence=AAG44625.1; Type=Frameshift; Positions=122, 225; Sequence=BAB47455.1; Type=Erroneousinitiation; Sequence=BAB55371.1; Type=Erroneous initiation;
Secondary accessions: Q96JK1 Q96JZ3 Q9H2N4Explore the universe of human proteins at neXtProt for MSANTD4: NX_Q8NCY6
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8NCY6
MSANTD4 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_115800.1
ENSEMBL proteins: ENSP00000304713 ENSP00000435125 ENSP00000432245 ENSP00000435372
Human Recombinant Protein Products for MSANTD4:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005634 | nucleus |
IDA | -- |
MSANTD4 for ontologies About GeneDecksing
MSANTD4 Antibody Products:
Assay Products for MSANTD4: |
Protein
Domains /
Families
for MSANTD4 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
MSANTD4 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q8NCY6ProtoNet protein and cluster: Q8NCY6 UniProtKB/Swiss-Prot: MSD4_HUMAN, Q8NCY6Similarity: Contains 1 Myb-like domain |
Function
for MSANTD4 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003677 | DNA binding |
-- | -- |
MSANTD4 for ontologies About GeneDecksing
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MSANTD4 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MSANTD4
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript Custom all cDNA clones Services for MSANTD4 | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MSANTD4 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MSANTD4 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MSANTD4 |
|
Pathways & Interactions
for MSANTD4 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MSANTD4
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
2 Interacting proteins for MSANTD4 (Q8NCY63 ENSP000003047134) via UniProtKB, MINT, STRING, and/or I2DAbout this table
|
Drugs & Compounds
for MSANTD4 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for MSANTD4
Search CenterWatch for drugs/clinical trials and news about MSANTD4 / MSD4
|
Transcripts
for MSANTD4 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for MSANTD4 gene: NM_032424.1 Unigene Cluster for MSANTD4: Myb/SANT-like DNA-binding domain containing 4 with coiled-coils Hs.266782 [show with all ESTs]Unigene Representative Sequence: NM_0324245 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000529805 ENST00000301919(uc001piy.3 uc001piz.3) ENST00000530788
ENST00000534458 ENST00000530108
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MSANTD4 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MSANTD4
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript Custom all cDNA clones Services for MSANTD4 | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MSANTD4 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MSANTD4 |
Additional cDNA sequence: AB058729.1 AF253976.1 AK027790.1 AK293050.1 AL834523.1 BC041118.1 9 DOTS entries: DT.407028 DT.100035733 DT.100668540 DT.426602 DT.120728060 DT.100650633 DT.99986623 DT.100716957 DT.40214313 24/83 AceView cDNA sequences (see all 83): BX504497 BM674853 AA443382 BM466510 Z40813 CR614328 CN484047 CR610578 BM454665 AI274543 BM755366 AB058729 AK027790 BQ187206 BC041118 BX279748 AL834523 AL521499 BM478735 AW105213 AW612499 BX352660 BU631259 BF432733
GeneLoc Exon Structure
5 Alternative Splicing Database (ASD) splice patterns (SP) for MSANTD4 About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | · | 1e | ^ | 2a | · | 2b | · | 2c | · | 2d | ^ | 3a | · | 3b |
|---|
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| SP1: | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | - | | - | | - | | | | | | | | | | | | | | |
| SP3: | | | | | | | - | | - | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | - | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | - | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for MSANTD4
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Expression
for MSANTD4 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| MSANTD4 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AGCTTGAACC
About this image
See MSANTD4 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for MSANTD4
SOURCE GeneReport for Unigene cluster: Hs.266782
SABiosciences Custom PCR Arrays for MSANTD4
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MSANTD4
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat MSANTD4 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MSANTD4 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MSANTD4 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MSANTD4 |
Orthologs
for MSANTD4 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for MSANTD4 gene from 5/13 species (see all 13) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Msantd45
Mysantd41 |
RIKEN cDNA 8430410K20 gene5
Myb/SANT-like DNA-binding domain containing 4 with more1 |
85.56(n)1
95.35(a)1 |
|
9 (2.46 cM)5
781001 NM_145609.11 NP_663584.11
43835355 |
chicken
(Gallus gallus) |
Aves |
MSANTD41 |
Myb/SANT-like DNA-binding domain containing 4 with more |
75.19(n)
79.07(a) |
|
418977 XM_417171.3 XP_417171.2 |
lizard
(Anolis carolinensis) |
Reptilia |
KIAA18266 |
-- |
79(a) |
1 ↔ 1 |
3(190363268-190366751) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.137872 |
Xenopus laevis transcribed sequence with weak similarity more |
74.12(n) |
|
CA972684.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
LOC5705861 |
coiled-coil domain-containing protein KIAA1826 homolog |
58.58(n)
54.68(a) |
|
570586 XM_694083.4 XP_699175.3 |
ENSEMBL Gene Tree for MSANTD4 (if available)
TreeFam Gene Tree for MSANTD4 (if available) |
Paralogs
for MSANTD4 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for MSANTD4 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 11 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for MSANTD4 (105866350 - 105893130 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for MSANTD4: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MSANTD4 |
|
Disorders
/ Diseases
for MSANTD4 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for MSANTD4 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for MSANTD4 gene, integrated from 9 sources (see all 14):
(articles sorted by number of sources associating them with MSANTD4) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 11347906)1, 2 Nagase T.... Ohara O. (2001)
- Comparative proteomic analysis identifies a role for S UMO in protein quality control. (PubMed id 21693764)1 Tatham M.H....Hay R.T. (2011)
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
- System-wide changes to SUMO modifications in response to heat shock. (PubMed id 19471022)1 Golebiowski F....Hay R.T. (2009)
- Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis. (PubMed id 18220336)2 Cantin G.T....Yates J.R. III (2008)
- The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
- The LIFEdb database in 2006. (PubMed id 16381901)1 Mehrle A....Wiemann S. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- From ORFeome to biology: a functional genomics pipeline. (PubMed id 15489336)1 Wiemann S....Poustka A. (2004)
|
External Searches for MSANTD4 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing MSANTD4 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing MSANTD4 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing MSANTD4 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for MSANTD4 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for MSANTD4 gene:
Search GeneIP for patents involving MSANTD4
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for MSANTD4 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for MSANTD4 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MSANTD4 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MSANTD4 | | | OriGene Protein Over-expression Lysate for MSANTD4 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for MSANTD4 | | OriGene 3'-UTR Clone for MSANTD4 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MSANTD4 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MSANTD4 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for MSANTD4 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for MSANTD4 | | OriGene Custom Protein Services for MSANTD4 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat MSANTD4 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MSANTD4 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MSANTD4 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MSANTD4 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MSANTD4 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MSANTD4 |
| |
 |  |  |  | |
| | | | Search Tocris compounds for MSANTD4 |
| |  |  |  |  | | | | |
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 |
 |
 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MSANTD4 |
|  |  |  |  | | | | ThermoFisher Antibodies for MSANTD4 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MSANTD4 |
| |  | |
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