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Aliases for MSANTD4 Gene

Aliases for MSANTD4 Gene

  • Myb/SANT DNA Binding Domain Containing 4 With Coiled-Coils 2 3 5
  • Myb/SANT-Like DNA-Binding Domain Containing 4 With Coiled-Coils 2 3 4
  • KIAA1826 2 3 4
  • Myb/SANT-Like DNA-Binding Domain-Containing Protein 4 3

External Ids for MSANTD4 Gene

Previous HGNC Symbols for MSANTD4 Gene

  • KIAA1826

Previous GeneCards Identifiers for MSANTD4 Gene

  • GC11M105866

Summaries for MSANTD4 Gene

GeneCards Summary for MSANTD4 Gene

MSANTD4 (Myb/SANT DNA Binding Domain Containing 4 With Coiled-Coils) is a Protein Coding gene.

Gene Wiki entry for MSANTD4 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MSANTD4 Gene

Genomics for MSANTD4 Gene

Regulatory Elements for MSANTD4 Gene

Enhancers for MSANTD4 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH11G106021 1.1 ENCODE 25.9 +0.1 106 2.1 PKNOX1 WRNIP1 ARID4B SIN3A DMAP1 YY1 ZNF143 FOS SP3 CEBPZ MSANTD4 LOC100422300 ENSG00000254433 RNU6-277P
GH11G106012 1 Ensembl ENCODE 25.5 +9.3 9342 1.7 JUN TCF12 ZNF366 TRIM24 FOS ZNF639 MTA2 HLF ZFP37 ZEB2 MSANTD4 RNU6-277P
GH11G105645 0.5 FANTOM5 1.8 +376.2 376210 0.4 ZNF639 GTF2E2 ZKSCAN8 GRIA4 MSANTD4 HSPD1P13
GH11G105803 0.3 FANTOM5 2 +218.4 218353 0.4 GRIA4 KBTBD3 MSANTD4 AASDHPPT RNU4-55P HSPD1P13
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MSANTD4 on UCSC Golden Path with GeneCards custom track

Promoters for MSANTD4 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000044347 303 1801 PKNOX1 MLX WRNIP1 SIN3A ARID4B DMAP1 YY1 ZNF143 FOS SP3

Genomic Location for MSANTD4 Gene

105,995,623 bp from pter
106,022,403 bp from pter
26,781 bases
Minus strand

Genomic View for MSANTD4 Gene

Genes around MSANTD4 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MSANTD4 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MSANTD4 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MSANTD4 Gene

Proteins for MSANTD4 Gene

  • Protein details for MSANTD4 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Myb/SANT-like DNA-binding domain-containing protein 4
    Protein Accession:
    Secondary Accessions:
    • Q96JK1
    • Q96JZ3
    • Q9H2N4

    Protein attributes for MSANTD4 Gene

    345 amino acids
    Molecular mass:
    41150 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAG44625.1; Type=Frameshift; Positions=122, 225; Evidence={ECO:0000305}; Sequence=BAB47455.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=BAB55371.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for MSANTD4 Gene

Post-translational modifications for MSANTD4 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for MSANTD4 Gene

Domains & Families for MSANTD4 Gene

Gene Families for MSANTD4 Gene

Protein Domains for MSANTD4 Gene

Suggested Antigen Peptide Sequences for MSANTD4 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MSANTD4: view

No data available for UniProtKB/Swiss-Prot for MSANTD4 Gene

Function for MSANTD4 Gene

Phenotypes for MSANTD4 Gene

GenomeRNAi human phenotypes for MSANTD4:
genes like me logo Genes that share phenotypes with MSANTD4: view

Animal Model Products

CRISPR Products

miRNA for MSANTD4 Gene

miRTarBase miRNAs that target MSANTD4

Inhibitory RNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for MSANTD4 Gene

Localization for MSANTD4 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MSANTD4 gene
Compartment Confidence
nucleus 5
cytosol 2

Gene Ontology (GO) - Cellular Components for MSANTD4 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IDA --
genes like me logo Genes that share ontologies with MSANTD4: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for MSANTD4 Gene

Pathways & Interactions for MSANTD4 Gene

SuperPathways for MSANTD4 Gene

No Data Available

Interacting Proteins for MSANTD4 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
Selected Interacting proteins: Q8NCY6-MSD4_HUMAN ENSP00000304713 for MSANTD4 Gene via IID STRING MINT

Gene Ontology (GO) - Biological Process for MSANTD4 Gene


No data available for Pathways by source and SIGNOR curated interactions for MSANTD4 Gene

Drugs & Compounds for MSANTD4 Gene

No Compound Related Data Available

Transcripts for MSANTD4 Gene

Unigene Clusters for MSANTD4 Gene

Myb/SANT-like DNA-binding domain containing 4 with coiled-coils:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MSANTD4 Gene

ExUns: 1a · 1b · 1c · 1d · 1e ^ 2a · 2b · 2c · 2d ^ 3a · 3b
SP2: - - -
SP3: - -
SP4: -
SP5: -

Relevant External Links for MSANTD4 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MSANTD4 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MSANTD4 Gene

Protein differential expression in normal tissues from HIPED for MSANTD4 Gene

This gene is overexpressed in Blymphocyte (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for MSANTD4 Gene

Protein tissue co-expression partners for MSANTD4 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of MSANTD4 Gene:


SOURCE GeneReport for Unigene cluster for MSANTD4 Gene:


Evidence on tissue expression from TISSUES for MSANTD4 Gene

  • Nervous system(4.6)
  • Lymph node(4.2)
  • Spleen(4.2)
  • Blood(4.1)
  • Skin(4.1)
genes like me logo Genes that share expression patterns with MSANTD4: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for MSANTD4 Gene

Orthologs for MSANTD4 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MSANTD4 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia MSANTD4 34 35
  • 99.42 (n)
(Bos Taurus)
Mammalia MSANTD4 34 35
  • 92.56 (n)
(Ornithorhynchus anatinus)
Mammalia MSANTD4 35
  • 86 (a)
(Mus musculus)
Mammalia Msantd4 34 16 35
  • 85.56 (n)
(Canis familiaris)
Mammalia MSANTD4 34 35
  • 85.22 (n)
(Rattus norvegicus)
Mammalia Msantd4 34
  • 85.08 (n)
(Monodelphis domestica)
Mammalia MSANTD4 35
  • 75 (a)
(Gallus gallus)
Aves MSANTD4 34 35
  • 74.42 (n)
(Anolis carolinensis)
Reptilia MSANTD4 35
  • 79 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia msantd4 34
  • 70.02 (n)
Str.11061 34
African clawed frog
(Xenopus laevis)
Amphibia Xl.13787 34
(Danio rerio)
Actinopterygii LOC570586 34
  • 58.73 (n)
msantd4 35
  • 43 (a)
Species where no ortholog for MSANTD4 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MSANTD4 Gene

Gene Tree for MSANTD4 (if available)
Gene Tree for MSANTD4 (if available)

Paralogs for MSANTD4 Gene

No data available for Paralogs for MSANTD4 Gene

Variants for MSANTD4 Gene

Sequence variations from dbSNP and Humsavar for MSANTD4 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs1000200735 -- 106,013,800(+) GAGGT(C/T)GCAGT intron-variant
rs1000228572 -- 106,008,928(+) CTACA(C/T)AGTAA utr-variant-3-prime
rs1000304806 -- 106,020,649(+) AGTTT(-/GACAGCAGC)GACAG intron-variant
rs1000348247 -- 106,018,543(+) ATCAA(C/T)GTTAA intron-variant
rs1000789696 -- 106,017,425(+) GGTGA(C/T)CAACA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for MSANTD4 Gene

Variant ID Type Subtype PubMed ID
dgv81n21 CNV loss 19592680
nsv1052674 CNV loss 25217958

Variation tolerance for MSANTD4 Gene

Residual Variation Intolerance Score: 15.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.38; 8.42% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for MSANTD4 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MSANTD4 Gene

Disorders for MSANTD4 Gene

Relevant External Links for MSANTD4

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MSANTD4 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MSANTD4 Gene

Publications for MSANTD4 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  2. Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 11347906) Nagase T. … Ohara O. (DNA Res. 2001) 3 4 64
  3. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein M.Y. … Mann M. (Cell 2015) 3 64
  4. System-wide analysis of SUMOylation dynamics in response to replication stress reveals novel small ubiquitin-like modified target proteins and acceptor lysines relevant for genome stability. (PMID: 25755297) Xiao Z. … Vertegaal A.C. (Mol. Cell. Proteomics 2015) 4 64
  5. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 64

Products for MSANTD4 Gene

Sources for MSANTD4 Gene

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