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Aliases for MSANTD4 Gene

Aliases for MSANTD4 Gene

  • Myb/SANT DNA Binding Domain Containing 4 With Coiled-Coils 2 3
  • Myb/SANT-Like DNA-Binding Domain Containing 4 With Coiled-Coils 2 3 4 5
  • KIAA1826 2 3 4

External Ids for MSANTD4 Gene

Previous HGNC Symbols for MSANTD4 Gene

  • KIAA1826

Previous GeneCards Identifiers for MSANTD4 Gene

  • GC11M105866

Summaries for MSANTD4 Gene

GeneCards Summary for MSANTD4 Gene

MSANTD4 (Myb/SANT DNA Binding Domain Containing 4 With Coiled-Coils) is a Protein Coding gene.

Gene Wiki entry for MSANTD4 Gene

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MSANTD4 Gene

Genomics for MSANTD4 Gene

Regulatory Elements for MSANTD4 Gene

Promoters for MSANTD4 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around MSANTD4 on UCSC Golden Path with GeneCards custom track

Genomic Location for MSANTD4 Gene

Chromosome:
11
Start:
105,995,623 bp from pter
End:
106,022,403 bp from pter
Size:
26,781 bases
Orientation:
Minus strand

Genomic View for MSANTD4 Gene

Genes around MSANTD4 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MSANTD4 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MSANTD4 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MSANTD4 Gene

Proteins for MSANTD4 Gene

  • Protein details for MSANTD4 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NCY6-MSD4_HUMAN
    Recommended name:
    Myb/SANT-like DNA-binding domain-containing protein 4
    Protein Accession:
    Q8NCY6
    Secondary Accessions:
    • Q96JK1
    • Q96JZ3
    • Q9H2N4

    Protein attributes for MSANTD4 Gene

    Size:
    345 amino acids
    Molecular mass:
    41150 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAG44625.1; Type=Frameshift; Positions=122, 225; Evidence={ECO:0000305}; Sequence=BAB47455.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=BAB55371.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for MSANTD4 Gene

Proteomics data for MSANTD4 Gene at MOPED

Post-translational modifications for MSANTD4 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for MSANTD4 Gene

Domains & Families for MSANTD4 Gene

Gene Families for MSANTD4 Gene

Protein Domains for MSANTD4 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for MSANTD4 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8NCY6

UniProtKB/Swiss-Prot:

MSD4_HUMAN :
  • Contains 1 Myb-like domain.
Domain:
  • Contains 1 Myb-like domain.
genes like me logo Genes that share domains with MSANTD4: view

Function for MSANTD4 Gene

Phenotypes for MSANTD4 Gene

GenomeRNAi human phenotypes for MSANTD4:
genes like me logo Genes that share phenotypes with MSANTD4: view

Animal Model Products

CRISPR Products

miRNA for MSANTD4 Gene

miRTarBase miRNAs that target MSANTD4

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for MSANTD4 Gene

Localization for MSANTD4 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for MSANTD4 Gene COMPARTMENTS Subcellular localization image for MSANTD4 gene
Compartment Confidence
nucleus 5
cytosol 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for MSANTD4 Gene

Pathways & Interactions for MSANTD4 Gene

SuperPathways for MSANTD4 Gene

No Data Available

Interacting Proteins for MSANTD4 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000304713%0d%0a9606.ENSP00000405965%0d%0a9606.ENSP00000334499%0d%0a
Selected Interacting proteins: ENSP00000304713 Q8NCY6-MSD4_HUMAN for MSANTD4 Gene via STRING I2D

Gene Ontology (GO) - Biological Process for MSANTD4 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MSANTD4 Gene

Drugs & Compounds for MSANTD4 Gene

No Compound Related Data Available

Transcripts for MSANTD4 Gene

Unigene Clusters for MSANTD4 Gene

Myb/SANT-like DNA-binding domain containing 4 with coiled-coils:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for MSANTD4 Gene

ExUns: 1a · 1b · 1c · 1d · 1e ^ 2a · 2b · 2c · 2d ^ 3a · 3b
SP1:
SP2: - - -
SP3: - -
SP4: -
SP5: -

Relevant External Links for MSANTD4 Gene

GeneLoc Exon Structure for
MSANTD4
ECgene alternative splicing isoforms for
MSANTD4

Expression for MSANTD4 Gene

mRNA expression in normal human tissues for MSANTD4 Gene

Protein differential expression in normal tissues from HIPED for MSANTD4 Gene

This gene is overexpressed in Blymphocyte (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MOPED, and MaxQB for MSANTD4 Gene



SOURCE GeneReport for Unigene cluster for MSANTD4 Gene Hs.266782

genes like me logo Genes that share expression patterns with MSANTD4: view

Protein tissue co-expression partners for MSANTD4 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for MSANTD4 Gene

Orthologs for MSANTD4 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MSANTD4 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia MSANTD4 35
  • 99.42 (n)
  • 100 (a)
MSANTD4 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia MSANTD4 36
  • 98 (a)
OneToOne
MSANTD4 35
  • 92.56 (n)
  • 97.68 (a)
dog
(Canis familiaris)
Mammalia MSANTD4 35
  • 85.22 (n)
  • 95.94 (a)
MSANTD4 36
  • 96 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Msantd4 16
Msantd4 36
  • 95 (a)
OneToOne
Msantd4 35
  • 85.56 (n)
  • 95.35 (a)
oppossum
(Monodelphis domestica)
Mammalia MSANTD4 36
  • 75 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia MSANTD4 36
  • 86 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Msantd4 35
  • 85.08 (n)
  • 95.64 (a)
chicken
(Gallus gallus)
Aves MSANTD4 36
  • 79 (a)
OneToOne
MSANTD4 35
  • 74.42 (n)
  • 78.2 (a)
lizard
(Anolis carolinensis)
Reptilia MSANTD4 36
  • 79 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.13787 35
tropical clawed frog
(Silurana tropicalis)
Amphibia msantd4 35
  • 70.02 (n)
  • 74.09 (a)
Str.11061 35
zebrafish
(Danio rerio)
Actinopterygii msantd4 36
  • 43 (a)
OneToOne
LOC570586 35
  • 58.73 (n)
  • 55.29 (a)
Species with no ortholog for MSANTD4:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MSANTD4 Gene

ENSEMBL:
Gene Tree for MSANTD4 (if available)
TreeFam:
Gene Tree for MSANTD4 (if available)

Paralogs for MSANTD4 Gene

No data available for Paralogs for MSANTD4 Gene

Variants for MSANTD4 Gene

Sequence variations from dbSNP and Humsavar for MSANTD4 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs2846218 -- 106,023,021(-) ccaca(A/G)aggcc upstream-variant-2KB
rs2846221 -- 106,011,134(-) TATAG(C/T)TCATT intron-variant
rs2847182 -- 106,013,358(+) GTATC(A/G)AACTA intron-variant
rs2847183 -- 106,013,636(+) cgggc(A/G)gattg intron-variant
rs9326351 -- 106,011,261(+) GCAAA(G/T)GTTCC intron-variant

Variation tolerance for MSANTD4 Gene

Residual Variation Intolerance Score: 15.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.38; 8.42% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for MSANTD4 Gene

HapMap Linkage Disequilibrium report
MSANTD4

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for MSANTD4 Gene

Disorders for MSANTD4 Gene

Relevant External Links for MSANTD4

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MSANTD4

No disorders were found for MSANTD4 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MSANTD4 Gene

Publications for MSANTD4 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 67
  2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  4. The LIFEdb database in 2006. (PMID: 16381901) Mehrle A. … Wiemann S. (Nucleic Acids Res. 2006) 3
  5. From ORFeome to biology: a functional genomics pipeline. (PMID: 15489336) Wiemann S. … Poustka A. (Genome Res. 2004) 3

Products for MSANTD4 Gene

Sources for MSANTD4 Gene

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