MSANTD3 Gene
protein-coding GIFtS: 38
GCID: GC09P103190
|
|
Myb/SANT-like DNA-binding domain containing 3(Previous name: chromosome 9 open reading frame 30 )
(Previous symbol: C9orf30)
| |
Aliases
for MSANTD3 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Myb/SANT-Like DNA-Binding Domain Containing 31 2 | | C9orf301 2 3 | | MGC173371 | | Chromosome 9 Open Reading Frame 301 | | Myb/SANT-Like DNA-Binding Domain-Containing Protein 32 | | UPF0439 Protein C9orf302 |
Export aliases for MSANTD3 gene to outside databases |
Summaries
for MSANTD3 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for MSANTD3 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000009.11 NC_018920.1 NT_008470.19
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for MSANTD3
Other transcription factors
Search SABiosciences Chromatin IP Primers for MSANTD3
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MSANTD3 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 9q31.1 Ensembl cytogenetic band: 9q31.1 HGNC cytogenetic band: 9q31.1MSANTD3 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 9 GeneLoc Exon Structure GeneLoc location for GC09P103190: view genomic region
(about GC identifiers)
Start:
|
103,189,438 bp from pter |
End:
|
103,213,513 bp from pter |
Size:
|
24,076 bases |
Orientation:
|
plus strand |
|
Proteins
for MSANTD3 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: MSD3_HUMAN, Q96H12 (See
protein sequence)Recommended Name: Myb/SANT-like DNA-binding domain-containing protein 3 Size: 275 amino acids; 32363 Da
Sequence caution: Sequence=CAI12539.1; Type=Erroneous gene model prediction; Sequence=CAI12540.1; Type=Erroneous genemodel prediction;
Secondary accessions: Q5T726 Q5T727 Q5T728Explore the universe of human proteins at neXtProt for MSANTD3: NX_Q96H12
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q96H12
MSANTD3 Protein expression data from MOPED and PaxDb: --
REFSEQ proteins (4 alternative transcripts):
NP_001185734.1 NP_001185735.1 NP_001185736.1 NP_542386.1
ENSEMBL proteins: ENSP00000378506 ENSP00000415830 ENSP00000364020 ENSP00000364021
Human Recombinant Protein Products:
MSANTD3 Antibody Products:
Assay Products for MSANTD3: |
Protein
Domains /
Families
for MSANTD3 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
MSANTD3 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q96H12ProtoNet protein and cluster: Q96H12 UniProtKB/Swiss-Prot: MSD3_HUMAN, Q96H12Similarity: Belongs to the MSANTD3 familySimilarity: Contains 1 Myb-like domain |
Function
for MSANTD3 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MSANTD3 (see all 6)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MSANTD3
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript Custom all cDNA clones Services for MSANTD3 | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MSANTD3 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MSANTD3 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MSANTD3 |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0042802 | identical protein binding |
IEA | -- |
MSANTD3 for ontologies About GeneDecksing
|
Pathways & Interactions
for MSANTD3 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MSANTD3
1 Interacting protein for MSANTD3 (Q96H122) via UniProtKB, MINT, STRING, and/or I2DAbout this table
|
Drugs & Compounds
for MSANTD3 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for MSANTD3
Search CenterWatch for drugs/clinical trials and news about MSANTD3 / MSD3
|
Transcripts
for MSANTD3 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for MSANTD3 gene (4 alternative transcripts): NM_001198805.1 NM_001198806.1 NM_001198807.1 NM_080655.2 Unigene Cluster for MSANTD3: Myb/SANT-like DNA-binding domain containing 3 Hs.530272 [show with all ESTs]Unigene Representative Sequence: AK0922925 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000395067(uc022bkz.1 uc004baw.3 uc022bla.1 uc022blb.1)
ENST00000398977 ENST00000374885 ENST00000374886 ENST00000489377(uc004bax.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MSANTD3 (see all 6)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MSANTD3
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript Custom all cDNA clones Services for MSANTD3 | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MSANTD3 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MSANTD3 |
Additional cDNA sequence: AK092292.1 AK314924.1 AY598327.1 BC008993.1 8 DOTS entries: DT.315057 DT.100793020 DT.100793021 DT.95158024 DT.100697305 DT.95366302 DT.99992052 DT.75153038 24/207 AceView cDNA sequences (see all 207): CD364475 AI224842 AW050404 AA084788 BE301253 BM559008 AF074684 BM854314 BU681367 BM841942 BU619044 NM_080655 BC008993 AI094181 BE018216 AA373648 BU741931 BM718343 CA425719 AI240420 CB161148 CR599657 AA227523 BE301701
GeneLoc Exon Structure
5 Alternative Splicing Database (ASD) splice patterns (SP) for MSANTD3 About this scheme
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | ^ | 3a | · | 3b | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | - | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for MSANTD3
|
Expression
for MSANTD3 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| MSANTD3 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GACTTGGCGG
About this image
Genevestigator expression for MSANTD3
SOURCE GeneReport for Unigene cluster: Hs.530272
UniProtKB/Swiss-Prot: MSD3_HUMAN, Q96H12Tissue specificity: Expressed in brain
SABiosciences Custom PCR Arrays for MSANTD3
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MSANTD3
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat MSANTD3 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MSANTD3 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MSANTD3 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MSANTD3 |
Orthologs
for MSANTD3 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for MSANTD3 gene from 5/12 species (see all 12) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Msantd35
Mysantd31 |
RIKEN cDNA 5730528L13 gene5
Myb/SANT-like DNA-binding domain containing 31 |
86.67(n)1
96.36(a)1 |
|
4 (26.13 cM)5
666651 NM_001145925.11 NP_001139397.11
485399355 |
chicken
(Gallus gallus) |
Aves |
MSANTD31 |
Myb/SANT-like DNA-binding domain containing 3 |
80.91(n)
93.36(a) |
|
420991 XM_419077.3 XP_419077.2 |
lizard
(Anolis carolinensis) |
Reptilia |
C9orf306 |
-- |
88(a) |
1 ↔ 1 |
6(54868107-54871291) |
African clawed frog
(Xenopus laevis) |
Amphibia |
mgc17337-prov2 |
hypothetical protein MGC53031 |
77.54(n) |
|
BC043625.1 |
honey bee
(Apis mellifera) |
Insecta |
-- |
-- |
25(a) |
1 ↔ 1 |
Group9.14(92934-94194) |
ENSEMBL Gene Tree for MSANTD3 (if available)
TreeFam Gene Tree for MSANTD3 (if available) |
Paralogs
for MSANTD3 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for MSANTD3 gene
MSANTD3 for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for MSANTD3
PGOHUM00000236998
|
Genomic Variants
for MSANTD3 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 9 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for MSANTD3 (103189438 - 103213513 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for MSANTD3: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MSANTD3 |
|
Disorders
/ Diseases
for MSANTD3 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
MSANTD3 for disorders About GeneDecksing
1  disease for MSANTD3: About MalaCardslung cancer
Export disorders for MSANTD3 gene to outside databases
|
Publications
for MSANTD3 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for MSANTD3 gene, integrated from 9 sources (see all 13):
(articles sorted by number of sources associating them with MSANTD3) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Suppression subtractive hybridization and expression profiling identifies a unique set of genes overexpressed in non-small-cell lung cancer. (PubMed id 15334068)1, 2 Petroziello J.... Carter P. (2004)
- System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (2011)
- Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
- Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (2010)
- Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (2009)
- A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (2008)
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)2 Olsen J.V....Mann M. (2006)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)
|
External Searches for MSANTD3 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing MSANTD3 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing MSANTD3 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing MSANTD3 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for MSANTD3 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for MSANTD3 gene:
Search GeneIP for patents involving MSANTD3
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for MSANTD3 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for MSANTD3 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MSANTD3 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MSANTD3 | | | OriGene Protein Over-expression Lysate for MSANTD3 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for MSANTD3 | | OriGene 3'-UTR Clone for MSANTD3 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MSANTD3 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MSANTD3 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for MSANTD3 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for MSANTD3 | | OriGene Custom Protein Services for MSANTD3 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat MSANTD3 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MSANTD3 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MSANTD3 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MSANTD3 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MSANTD3 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MSANTD3 |
| |
 |  |  |  | |
| | | | Search Tocris compounds for MSANTD3 |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | MSANTD3 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MSANTD3 |
|  |  |  | | | | Search ThermoFisher Antibodies for MSANTD3 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MSANTD3 |
|
|
|
|
