MSANTD2 Gene
protein-coding GIFtS: 37
GCID: GC11M124637
|
|
Myb/SANT-like DNA-binding domain containing 2(Previous name: chromosome 11 open reading frame 61 )
(Previous symbol: C11orf61)
| |
Aliases
for MSANTD2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Myb/SANT-Like DNA-Binding Domain Containing 21 2 | | C11orf611 2 3 | | FLJ233421 | | Chromosome 11 Open Reading Frame 611 | | Myb/SANT-Like DNA-Binding Domain-Containing Protein 22 |
Export aliases for MSANTD2 gene to outside databases |
Summaries
for MSANTD2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for MSANTD2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000011.9 NC_018922.1 NT_033899.8
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for MSANTD2
Other transcription factors
Search SABiosciences Chromatin IP Primers for MSANTD2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MSANTD2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 11q24.2 Ensembl cytogenetic band: 11q24.2 HGNC cytogenetic band: 11q24.2MSANTD2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 11 GeneLoc Exon Structure GeneLoc location for GC11M124637: view genomic region
(about GC identifiers)
Start:
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124,636,394 bp from pter |
End:
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124,670,569 bp from pter |
Size:
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34,176 bases |
Orientation:
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minus strand |
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Proteins
for MSANTD2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: MSD2_HUMAN, Q6P1R3 (See
protein sequence)Recommended Name: Myb/SANT-like DNA-binding domain-containing protein 2 Size: 559 amino acids; 61319 Da
Secondary accessions: B3KRY6 Q9H042 Q9H5K8Alternative splicing: 3 isoforms: Q6P1R3-1 Q6P1R3-2 Q6P1R3-3 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for MSANTD2: NX_Q6P1R3
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q6P1R3
MSANTD2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_078907.2
ENSEMBL proteins: ENSP00000239614 ENSP00000364118 ENSP00000435705 ENSP00000431707 ENSP00000434572
Human Recombinant Protein Products:
MSANTD2 Antibody Products:
Assay Products for MSANTD2: |
Protein
Domains /
Families
for MSANTD2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q6P1R3 UniProtKB/Swiss-Prot: MSD2_HUMAN, Q6P1R3Similarity: Contains 1 Myb-like domain |
Function
for MSANTD2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MSANTD2 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MSANTD2
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript Custom all cDNA clones Services for MSANTD2 | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MSANTD2 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MSANTD2 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MSANTD2 |
|
Pathways & Interactions
for MSANTD2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MSANTD2
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
2 Interacting proteins for MSANTD2 (Q6P1R32, 3 ENSP000002396144) via UniProtKB, MINT, STRING, and/or I2DAbout this table
|
Drugs & Compounds
for MSANTD2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for MSANTD2
Search CenterWatch for drugs/clinical trials and news about MSANTD2 / MSD2
|
Transcripts
for MSANTD2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for MSANTD2 gene: NM_024631.2 Unigene Cluster for MSANTD2: Myb/SANT-like DNA-binding domain containing 2 Hs.146079 [show with all ESTs]Unigene Representative Sequence: AL5126916 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000239614(uc001qaz.1 uc010sap.1) ENST00000374979(uc001qba.1)
ENST00000526629(uc001qay.1) ENST00000524950 ENST00000533514 ENST00000527140
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MSANTD2 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MSANTD2
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript Custom all cDNA clones Services for MSANTD2 | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MSANTD2 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MSANTD2 |
Additional cDNA sequence: AK026995.1 AK092413.1 AK303902.1 AL512691.1 BC064919.1 5 DOTS entries: DT.75140066 DT.313788 DT.97834666 DT.100777127 DT.75175343 24/70 AceView cDNA sequences (see all 70): AU280226 AA009726 AL512691 AI251765 AA447088 BQ421244 AA009422 BX102095 AK092413 BC064919 BP376140 BQ005450 BP375342 BP375857 H83931 BX326989 BX352996 AA491180 BE502240 BE463607 BE894175 AA810427 BP346024 BX470919
GeneLoc Exon Structure
5/6 Alternative Splicing Database (ASD) splice patterns (SP) for MSANTD2 (see all 6) About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3a | · | 3b | · | 3c | · | 3d | ^ | 4a | · | 4b | · | 4c | ^ | 5a | · | 5b | · | 5c | · | 5d |
|---|
|
| SP1: | | | | | - | | - | | | | | | | | - | | | | | | | | | | | | | | |
| SP2: | | | | | - | | - | | - | | | | | | - | | | | | | | | | | | | | | |
| SP3: | | | | | - | | - | | - | | - | | | | - | | | | | | | | | | | | | | |
| SP4: | | | | | | | - | | | | | | | | - | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | - | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for MSANTD2
|
Expression
for MSANTD2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| MSANTD2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GTGGGTCAGC
About this image
See MSANTD2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for MSANTD2
SOURCE GeneReport for Unigene cluster: Hs.146079
SABiosciences Custom PCR Arrays for MSANTD2
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MSANTD2
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat MSANTD2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MSANTD2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MSANTD2 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MSANTD2 |
Orthologs
for MSANTD2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for MSANTD2 gene from 5/11 species (see all 11) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Msantd21 , 5 |
cDNA sequence BC0244795
Myb/SANT-like DNA-binding domain containing 21 |
92.18(n)1
96.45(a)1 |
|
9 (20.77 cM)5
2351841 NM_146222.21 NP_666334.21
374893215 |
chicken
(Gallus gallus) |
Aves |
MSANTD21 |
Myb/SANT-like DNA-binding domain containing 2 |
79.97(n)
88.22(a) |
|
768763 NM_001109786.1 NP_001103256.1 |
lizard
(Anolis carolinensis) |
Reptilia |
C11orf616 |
-- |
78(a) |
1 ↔ 1 |
GL343367.1(82340-92679) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.225562 |
Xenopus laevis transcribed sequence with moderate similarity more |
76.08(n) |
|
48032271 |
zebrafish
(Danio rerio) |
Actinopterygii |
LOC7993681 |
uncharacterized protein C11orf61 homolog |
65.52(n)
67.81(a) |
|
799368 XM_001339696.1 XP_001339732.1 |
ENSEMBL Gene Tree for MSANTD2 (if available)
TreeFam Gene Tree for MSANTD2 (if available) |
Paralogs
for MSANTD2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for MSANTD2 gene
MSANTD2 for paralogs About GeneDecksing
2 Pseudogenes.org Pseudogenes for MSANTD2
PGOHUM00000248680 PGOHUM00000258121
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Genomic Variants
for MSANTD2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 11 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for MSANTD2 (124636394 - 124670569 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for MSANTD2: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MSANTD2 |
|
Disorders
/ Diseases
for MSANTD2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for MSANTD2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for MSANTD2 gene integrated from 9 sources:
(articles sorted by number of sources associating them with MSANTD2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (2009)
- Coeliac disease associated risk variants in TNFAIP3 and REL implicate altered NF-{kappa}B signalling. (PubMed id 19240061)1 Trynka G....Wijmenga C. (2009)
- Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis. (PubMed id 18220336)2 Cantin G.T....Yates J.R. III (2008)
- The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
- A human protein-protein interaction network: a resource for annotating the proteome. (PubMed id 16169070)1 Stelzl U.... Wanker E.E. (2005)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for MSANTD2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing MSANTD2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing MSANTD2 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing MSANTD2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for MSANTD2 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for MSANTD2 gene:
Search GeneIP for patents involving MSANTD2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for MSANTD2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for MSANTD2 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MSANTD2 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MSANTD2 | | | OriGene Protein Over-expression Lysate for MSANTD2 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for MSANTD2 | | OriGene 3'-UTR Clone for MSANTD2 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MSANTD2 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MSANTD2 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for MSANTD2 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for MSANTD2 | | OriGene Custom Protein Services for MSANTD2 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat MSANTD2 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MSANTD2 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MSANTD2 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MSANTD2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MSANTD2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MSANTD2 |
| |
 |  |  |  | |
| | | | Search Tocris compounds for MSANTD2 |
| |  |  |  |  | | | | |
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 | | | MSANTD2 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MSANTD2 |
|  |  |  | | | | Search ThermoFisher Antibodies for MSANTD2 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MSANTD2 |
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