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Aliases for MSANTD2 Gene

Aliases for MSANTD2 Gene

  • Myb/SANT DNA Binding Domain Containing 2 2 3
  • Myb/SANT-Like DNA-Binding Domain Containing 2 2 3 5
  • C11orf61 3 4
  • Chromosome 11 Open Reading Frame 61 2

External Ids for MSANTD2 Gene

Previous HGNC Symbols for MSANTD2 Gene

  • C11orf61

Previous GeneCards Identifiers for MSANTD2 Gene

  • GC11M124637

Summaries for MSANTD2 Gene

GeneCards Summary for MSANTD2 Gene

MSANTD2 (Myb/SANT DNA Binding Domain Containing 2) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MSANTD2 Gene

Genomics for MSANTD2 Gene

Regulatory Elements for MSANTD2 Gene

Promoters for MSANTD2 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around MSANTD2 on UCSC Golden Path with GeneCards custom track

Genomic Location for MSANTD2 Gene

Chromosome:
11
Start:
124,766,492 bp from pter
End:
124,800,673 bp from pter
Size:
34,182 bases
Orientation:
Minus strand

Genomic View for MSANTD2 Gene

Genes around MSANTD2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MSANTD2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MSANTD2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MSANTD2 Gene

Proteins for MSANTD2 Gene

  • Protein details for MSANTD2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6P1R3-MSD2_HUMAN
    Recommended name:
    Myb/SANT-like DNA-binding domain-containing protein 2
    Protein Accession:
    Q6P1R3
    Secondary Accessions:
    • B3KRY6
    • Q9H042
    • Q9H5K8

    Protein attributes for MSANTD2 Gene

    Size:
    559 amino acids
    Molecular mass:
    61319 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for MSANTD2 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for MSANTD2 Gene

Proteomics data for MSANTD2 Gene at MOPED

Post-translational modifications for MSANTD2 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for MSANTD2 Gene

Domains & Families for MSANTD2 Gene

Gene Families for MSANTD2 Gene

Protein Domains for MSANTD2 Gene

ProtoNet:

Suggested Antigen Peptide Sequences for MSANTD2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q6P1R3

UniProtKB/Swiss-Prot:

MSD2_HUMAN :
  • Contains 1 Myb-like domain.
Domain:
  • Contains 1 Myb-like domain.
genes like me logo Genes that share domains with MSANTD2: view

Function for MSANTD2 Gene

genes like me logo Genes that share phenotypes with MSANTD2: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for MSANTD2 Gene

Localization for MSANTD2 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for MSANTD2 Gene COMPARTMENTS Subcellular localization image for MSANTD2 gene
Compartment Confidence
nucleus 3
cytosol 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for MSANTD2 Gene

Pathways & Interactions for MSANTD2 Gene

SuperPathways for MSANTD2 Gene

No Data Available

Interacting Proteins for MSANTD2 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000239614%0d%0a9606.ENSP00000285398%0d%0a
Selected Interacting proteins: Q6P1R3-MSD2_HUMAN ENSP00000239614 for MSANTD2 Gene via MINT I2D STRING

Gene Ontology (GO) - Biological Process for MSANTD2 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MSANTD2 Gene

Drugs & Compounds for MSANTD2 Gene

No Compound Related Data Available

Transcripts for MSANTD2 Gene

Unigene Clusters for MSANTD2 Gene

Myb/SANT-like DNA-binding domain containing 2:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for MSANTD2 Gene

ExUns: 1a · 1b ^ 2 ^ 3a · 3b · 3c · 3d ^ 4a · 4b · 4c ^ 5a · 5b · 5c · 5d
SP1: - - -
SP2: - - - -
SP3: - - - - -
SP4: - -
SP5: -
SP6:

Relevant External Links for MSANTD2 Gene

GeneLoc Exon Structure for
MSANTD2
ECgene alternative splicing isoforms for
MSANTD2

Expression for MSANTD2 Gene

mRNA expression in normal human tissues for MSANTD2 Gene

Protein differential expression in normal tissues from HIPED for MSANTD2 Gene

This gene is overexpressed in Fetal testis (43.7), Fetal heart (10.9), Placenta (7.2), and Blymphocyte (7.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for MSANTD2 Gene



SOURCE GeneReport for Unigene cluster for MSANTD2 Gene Hs.146079

genes like me logo Genes that share expression patterns with MSANTD2: view

Protein tissue co-expression partners for MSANTD2 Gene

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for MSANTD2 Gene

Orthologs for MSANTD2 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MSANTD2 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia MSANTD2 36
  • 89 (a)
OneToOne
dog
(Canis familiaris)
Mammalia MSANTD2 36
  • 89 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia MSANTD2 36
  • 87 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Msantd2 36
  • 88 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia MSANTD2 36
  • 86 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia MSANTD2 36
  • 90 (a)
OneToOne
chicken
(Gallus gallus)
Aves C11ORF61 36
  • 81 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia MSANTD2 36
  • 79 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.22556 35
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.7243 35
zebrafish
(Danio rerio)
Actinopterygii MSANTD2 36
  • 61 (a)
OneToOne
Species with no ortholog for MSANTD2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MSANTD2 Gene

ENSEMBL:
Gene Tree for MSANTD2 (if available)
TreeFam:
Gene Tree for MSANTD2 (if available)

Paralogs for MSANTD2 Gene

Pseudogenes.org Pseudogenes for MSANTD2 Gene

genes like me logo Genes that share paralogs with MSANTD2: view

No data available for Paralogs for MSANTD2 Gene

Variants for MSANTD2 Gene

Sequence variations from dbSNP and Humsavar for MSANTD2 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs485469 -- 124,787,287(+) AACCC(C/T)TACCC intron-variant
rs534337 -- 124,796,170(+) CAATA(C/T)TTATA intron-variant
rs520648 -- 124,770,327(+) ttttt(G/T)ggaga intron-variant
rs491060 -- 124,797,455(+) TCACG(C/T)TACTG intron-variant
rs491158 -- 124,797,478(+) GGCAA(A/C)AGAGC intron-variant

Variation tolerance for MSANTD2 Gene

Residual Variation Intolerance Score: 14.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.75; 15.80% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for MSANTD2 Gene

HapMap Linkage Disequilibrium report
MSANTD2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for MSANTD2 Gene

Disorders for MSANTD2 Gene

Relevant External Links for MSANTD2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MSANTD2

No disorders were found for MSANTD2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MSANTD2 Gene

Publications for MSANTD2 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  3. Biological insights from 108 schizophrenia-associated genetic loci. (PMID: 25056061) (Nature 2014) 3
  4. Toward an understanding of the protein interaction network of the human liver. (PMID: 21988832) Wang J. … Yang X. (Mol. Syst. Biol. 2011) 3
  5. Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling. (PMID: 19240061) Trynka G. … Wijmenga C. (Gut 2009) 3

Products for MSANTD2 Gene

Sources for MSANTD2 Gene

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