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Aliases for MSANTD1 Gene

Aliases for MSANTD1 Gene

  • Myb/SANT DNA Binding Domain Containing 1 2 3 5
  • Myb/SANT-Like DNA-Binding Domain Containing 1 2 3
  • C4orf44 3 4
  • Myb/SANT-Like DNA-Binding Domain-Containing Protein 1 3
  • Chromosome 4 Open Reading Frame 44 2

External Ids for MSANTD1 Gene

Previous HGNC Symbols for MSANTD1 Gene

  • C4orf44

Summaries for MSANTD1 Gene

GeneCards Summary for MSANTD1 Gene

MSANTD1 (Myb/SANT DNA Binding Domain Containing 1) is a Protein Coding gene.

Additional gene information for MSANTD1 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MSANTD1 Gene

Genomics for MSANTD1 Gene

Regulatory Elements for MSANTD1 Gene

Enhancers for MSANTD1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH04H003319 1.4 Ensembl ENCODE dbSUPER 8.5 +80.1 80121 3 ELF3 FOXA2 ARID4B FEZF1 RAD21 SCRT2 OVOL3 TSHZ1 REST ZNF843 RGS12 MSANTD1 HTT-AS GC04M003323 LOC100286945
GH04H003110 1.1 Ensembl ENCODE 10.5 -129.4 -129374 3 PKNOX1 ESRRA JUN BMI1 ZNF7 CTBP1 ZNF316 GATA3 POLR2A FOS HTT HTT-AS RNU6-204P RNU7-33P MSANTD1 GC04M003105 GC04P003121
GH04H003207 0.9 ENCODE 11.8 -33.9 -33850 0 ELF3 FOXA2 ATF1 MLX RAD21 RARA YY1 CREM MIXL1 HMG20B MSANTD1 RGS12 GC04M003145
GH04H003250 0.6 ENCODE 16.6 +9.2 9201 0 TFAP4 ESRRA SAP130 SP5 EBF1 BCL11B MSANTD1 GC04M003284
GH04H003073 1.1 ENCODE 8.4 -166.4 -166413 3 HDGF PKNOX1 ATF1 FOXA2 MLX ARID4B SIN3A DMAP1 BRCA1 YY1 RNF4 FAM193A HAUS3 MSANTD1 HTT DOK7 NOP14-AS1 HTT-AS GC04M003078
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MSANTD1 on UCSC Golden Path with GeneCards custom track

Genomic Location for MSANTD1 Gene

Chromosome:
4
Start:
3,241,598 bp from pter
End:
3,271,738 bp from pter
Size:
30,141 bases
Orientation:
Plus strand

Genomic View for MSANTD1 Gene

Genes around MSANTD1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MSANTD1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MSANTD1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MSANTD1 Gene

Proteins for MSANTD1 Gene

  • Protein details for MSANTD1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6ZTZ1-MSD1_HUMAN
    Recommended name:
    Myb/SANT-like DNA-binding domain-containing protein 1
    Protein Accession:
    Q6ZTZ1
    Secondary Accessions:
    • C9J6V0

    Protein attributes for MSANTD1 Gene

    Size:
    278 amino acids
    Molecular mass:
    31632 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAC86436.1; Type=Miscellaneous discrepancy; Note=Probable cloning artifact.; Evidence={ECO:0000305};

neXtProt entry for MSANTD1 Gene

Post-translational modifications for MSANTD1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for MSANTD1 Gene

Domains & Families for MSANTD1 Gene

Gene Families for MSANTD1 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for MSANTD1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MSANTD1: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MSANTD1 Gene

Function for MSANTD1 Gene

Phenotypes From GWAS Catalog for MSANTD1 Gene

Phenotypes for MSANTD1 Gene

MGI mutant phenotypes for MSANTD1:
inferred from 1 alleles
GenomeRNAi human phenotypes for MSANTD1:
genes like me logo Genes that share phenotypes with MSANTD1: view

Animal Models for MSANTD1 Gene

MGI Knock Outs for MSANTD1:

Animal Model Products

CRISPR Products

miRNA for MSANTD1 Gene

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for MSANTD1
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for MSANTD1 Gene

Localization for MSANTD1 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MSANTD1 gene
Compartment Confidence
nucleus 3
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MSANTD1 Gene

Pathways & Interactions for MSANTD1 Gene

SuperPathways for MSANTD1 Gene

No Data Available

Interacting Proteins for MSANTD1 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
http://version10.5.string-db.org/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000411584%0d%0a9606.ENSP00000273375%0d%0a9606.ENSP00000268057%0d%0a
Selected Interacting proteins: ENSP00000411584 for MSANTD1 Gene via STRING

Gene Ontology (GO) - Biological Process for MSANTD1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MSANTD1 Gene

Drugs & Compounds for MSANTD1 Gene

No Compound Related Data Available

Transcripts for MSANTD1 Gene

mRNA/cDNA for MSANTD1 Gene

Unigene Clusters for MSANTD1 Gene

Myb/SANT-like DNA-binding domain containing 1:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for MSANTD1
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for MSANTD1 Gene

No ASD Table

Relevant External Links for MSANTD1 Gene

GeneLoc Exon Structure for
MSANTD1
ECgene alternative splicing isoforms for
MSANTD1

Expression for MSANTD1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MSANTD1 Gene

Protein differential expression in normal tissues from HIPED for MSANTD1 Gene

This gene is overexpressed in Pancreas (56.0) and Retina (13.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for MSANTD1 Gene



Protein tissue co-expression partners for MSANTD1 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of MSANTD1 Gene:

MSANTD1

SOURCE GeneReport for Unigene cluster for MSANTD1 Gene:

Hs.442291
genes like me logo Genes that share expression patterns with MSANTD1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MSANTD1 Gene

Orthologs for MSANTD1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MSANTD1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia MSANTD1 33 34
  • 99.76 (n)
dog
(Canis familiaris)
Mammalia MSANTD1 34 33
  • 92.82 (n)
OneToOne
cow
(Bos Taurus)
Mammalia MSANTD1 33 34
  • 92.56 (n)
rat
(Rattus norvegicus)
Mammalia Msantd1 33
  • 90.05 (n)
mouse
(Mus musculus)
Mammalia Msantd1 33 16 34
  • 89.33 (n)
oppossum
(Monodelphis domestica)
Mammalia MSANTD1 34
  • 79 (a)
OneToOne
chicken
(Gallus gallus)
Aves MSANTD1 34
  • 75 (a)
OneToOne
C4H4ORF44 33
  • 69.6 (n)
lizard
(Anolis carolinensis)
Reptilia MSANTD1 34
  • 78 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia msantd1 33
  • 74.24 (n)
zebrafish
(Danio rerio)
Actinopterygii LOC798497 33
  • 58.91 (n)
BX324131.3 34
  • 49 (a)
OneToOne
Species where no ortholog for MSANTD1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MSANTD1 Gene

ENSEMBL:
Gene Tree for MSANTD1 (if available)
TreeFam:
Gene Tree for MSANTD1 (if available)

Paralogs for MSANTD1 Gene

No data available for Paralogs for MSANTD1 Gene

Variants for MSANTD1 Gene

Sequence variations from dbSNP and Humsavar for MSANTD1 Gene

SNP ID Clin Chr 04 pos Sequence Context AA Info Type
rs1000296259 -- 3,256,104(+) AGGAT(A/G)TCCCT utr-variant-3-prime
rs1000360138 -- 3,247,037(+) TGGTG(A/G)TGGTG intron-variant, utr-variant-5-prime
rs1000369699 -- 3,246,776(+) CTCAC(A/C)TTGGA intron-variant, utr-variant-5-prime
rs1000671925 -- 3,250,672(+) GGGCT(A/G)GGCCT intron-variant
rs1000742514 -- 3,245,953(+) GGGTT(C/T)CCCTT intron-variant, utr-variant-5-prime

Structural Variations from Database of Genomic Variants (DGV) for MSANTD1 Gene

Variant ID Type Subtype PubMed ID
nsv470003 CNV loss 18288195
nsv524211 CNV loss 19592680
nsv949760 CNV deletion 24416366

Variation tolerance for MSANTD1 Gene

Residual Variation Intolerance Score: 44.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 7.04; 80.23% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for MSANTD1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MSANTD1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MSANTD1 Gene

Disorders for MSANTD1 Gene

Relevant External Links for MSANTD1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MSANTD1

No disorders were found for MSANTD1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MSANTD1 Gene

Publications for MSANTD1 Gene

  1. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier LW … Wilson RK (Nature 2005) 4 60
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 4 60
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 60
  4. Normalization and subtraction: two approaches to facilitate gene discovery. (PMID: 8889548) Bonaldo MF … Soares MB (Genome research 1996) 3 60

Products for MSANTD1 Gene

Sources for MSANTD1 Gene

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