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Aliases for MS4A18 Gene

Aliases for MS4A18 Gene

  • Membrane-Spanning 4-Domains, Subfamily A, Member 18 2 3

External Ids for MS4A18 Gene

Previous GeneCards Identifiers for MS4A18 Gene

  • GC11P060246
  • GC11P060489

Summaries for MS4A18 Gene

GeneCards Summary for MS4A18 Gene

MS4A18 (Membrane-Spanning 4-Domains, Subfamily A, Member 18) is a Protein Coding gene. An important paralog of this gene is MS4A8.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MS4A18 Gene

Genomics for MS4A18 Gene

Genomic Location for MS4A18 Gene

60,729,304 bp from pter
60,744,212 bp from pter
14,909 bases
Plus strand

Genomic View for MS4A18 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MS4A18 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MS4A18 Gene

No data available for Regulatory Elements for MS4A18 Gene

Proteins for MS4A18 Gene

  • Protein details for MS4A18 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Membrane-spanning 4-domains subfamily A member 18
    Protein Accession:
    Secondary Accessions:

    Protein attributes for MS4A18 Gene

    323 amino acids
    Molecular mass:
    34465 Da
    Quaternary structure:
    No Data Available

neXtProt entry for MS4A18 Gene

Proteomics data for MS4A18 Gene at MOPED

Post-translational modifications for MS4A18 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for MS4A18 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for MS4A18 Gene

Domains for MS4A18 Gene

Gene Families for MS4A18 Gene

Protein Domains for MS4A18 Gene


Suggested Antigen Peptide Sequences for MS4A18 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the MS4A family.
  • Belongs to the MS4A family.
genes like me logo Genes that share domains with MS4A18: view

Function for MS4A18 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MS4A18 Gene

Localization for MS4A18 Gene

Subcellular locations from UniProtKB/Swiss-Prot for MS4A18 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for MS4A18 Gene COMPARTMENTS Subcellular localization image for MS4A18 gene
Compartment Confidence
extracellular 2
cytosol 1
nucleus 1

Gene Ontology (GO) - Cellular Components for MS4A18 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with MS4A18: view

Pathways for MS4A18 Gene

SuperPathways for MS4A18 Gene

No Data Available

Interacting Proteins for MS4A18 Gene

Gene Ontology (GO) - Biological Process for MS4A18 Gene


No data available for Pathways by source for MS4A18 Gene

Transcripts for MS4A18 Gene

mRNA/cDNA for MS4A18 Gene

(6) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for MS4A18 Gene

Membrane-spanning 4-domains, subfamily A, member 18:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for MS4A18 Gene

No ASD Table

Relevant External Links for MS4A18 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MS4A18 Gene

mRNA expression in normal human tissues for MS4A18 Gene

mRNA differential expression in normal tissues according to GTEx for MS4A18 Gene

This gene is overexpressed in Testis (33.5) and Small Intestine - Terminal Ileum (13.5).

Protein differential expression in normal tissues for MS4A18 Gene

This gene is overexpressed in Platelet (69.0).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for MS4A18 Gene

SOURCE GeneReport for Unigene cluster for MS4A18 Gene Hs.739039

genes like me logo Genes that share expressions with MS4A18: view

Expression partners for MS4A18 Gene

* - Elite partner

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for MS4A18 Gene

Orthologs for MS4A18 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MS4A18 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia MS4A18 36
  • 53 (a)
(Canis familiaris)
Mammalia -- 36
  • 24 (a)
(Mus musculus)
Mammalia Ms4a18 36
  • 51 (a)
(Pan troglodytes)
Mammalia MS4A18 36
  • 98 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 27 (a)
-- 36
  • 30 (a)
-- 36
  • 22 (a)
(Danio rerio)
Actinopterygii FP015791.1 36
  • 26 (a)
ms4a17a.1 36
  • 24 (a)
ms4a17a.10 36
  • 24 (a)
ms4a17a.11 36
  • 26 (a)
ms4a17a.14 36
  • 29 (a)
ms4a17a.17 36
  • 20 (a)
ms4a17a.2 36
  • 23 (a)
ms4a17a.3 36
  • 24 (a)
ms4a17a.4 36
  • 23 (a)
ms4a17a.5 36
  • 25 (a)
ms4a17a.6 36
  • 26 (a)
ms4a17a.7 36
  • 22 (a)
ms4a17a.8 36
  • 20 (a)
ms4a17a.9 36
  • 21 (a)
ms4a17c.1 36
  • 21 (a)
ms4a17c.2 36
  • 21 (a)
si:ch73-56d11.3 36
  • 23 (a)
si:ch73-56d11.4 36
  • 23 (a)
si:dkey-174k12.3 36
  • 21 (a)
si:dkey-238j22.1 36
  • 20 (a)
si:dkey-77f5.10 36
  • 24 (a)
Species with no ortholog for MS4A18:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MS4A18 Gene

Gene Tree for MS4A18 (if available)
Gene Tree for MS4A18 (if available)

Paralogs for MS4A18 Gene

Paralogs for MS4A18 Gene

(2) SIMAP similar genes for MS4A18 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with MS4A18: view

Variants for MS4A18 Gene

Sequence variations from dbSNP and Humsavar for MS4A18 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs184394225 -- 60,738,142(+) AAATG(C/T)AGAAC intron-variant
rs183700695 -- 60,743,326(+) GGGCA(C/G)TCCCA intron-variant
rs183570912 -- 60,741,612(+) ATGGC(C/T)GAACC intron-variant
rs183482148 -- 60,735,637(+) TGGCC(A/G)ATTTA intron-variant
rs183451989 -- 60,731,159(+) TGTGC(A/G)GAAAT upstream-variant-2KB

Relevant External Links for MS4A18 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for MS4A18 Gene

Disorders for MS4A18 Gene

No disorders were found for MS4A18 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for MS4A18 Gene

Publications for MS4A18 Gene

  1. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PMID: 16554811) Taylor T.D. … Sakaki Y. (Nature 2006) 4

Products for MS4A18 Gene

Sources for MS4A18 Gene

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