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Aliases for MS4A14 Gene

Aliases for MS4A14 Gene

  • Membrane-Spanning 4-Domains, Subfamily A, Member 14 2 3
  • Membrane-Spanning 4-Domains, Subfamily A, Member 16 2 3
  • Testis Development Protein NYD-SP21 3 4
  • MS4A16 3 4
  • Membrane-Spanning 4-Domains Subfamily A Member 14 3
  • Testes Development-Related NYD-SP21 3
  • MS4A13 Protein 3
  • NYD-SP21 3
  • MS4A13 4

External Ids for MS4A14 Gene

Previous HGNC Symbols for MS4A14 Gene

  • MS4A16

Previous GeneCards Identifiers for MS4A14 Gene

  • GC11P059922
  • GC11P060163
  • GC11P056510

Summaries for MS4A14 Gene

GeneCards Summary for MS4A14 Gene

MS4A14 (Membrane-Spanning 4-Domains, Subfamily A, Member 14) is a Protein Coding gene. An important paralog of this gene is MS4A5.

UniProtKB/Swiss-Prot for MS4A14 Gene

  • May be involved in signal transduction as a component of a multimeric receptor complex.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MS4A14 Gene

Genomics for MS4A14 Gene

Regulatory Elements for MS4A14 Gene

Genomic Location for MS4A14 Gene

60,378,530 bp from pter
60,417,756 bp from pter
39,227 bases
Plus strand

Genomic View for MS4A14 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MS4A14 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MS4A14 Gene

Proteins for MS4A14 Gene

  • Protein details for MS4A14 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Membrane-spanning 4-domains subfamily A member 14
    Protein Accession:
    Secondary Accessions:
    • E9PJE3
    • Q2TVT5
    • Q3B7W3
    • Q86XH8
    • Q9NTC2

    Protein attributes for MS4A14 Gene

    679 amino acids
    Molecular mass:
    76580 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for MS4A14 Gene


neXtProt entry for MS4A14 Gene

Proteomics data for MS4A14 Gene at MOPED

Post-translational modifications for MS4A14 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for MS4A14 Gene

Domains for MS4A14 Gene

Gene Families for MS4A14 Gene

Protein Domains for MS4A14 Gene

Suggested Antigen Peptide Sequences for MS4A14 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the MS4A family.
  • Belongs to the MS4A family.
genes like me logo Genes that share domains with MS4A14: view

Function for MS4A14 Gene

Molecular function for MS4A14 Gene

UniProtKB/Swiss-Prot Function:
May be involved in signal transduction as a component of a multimeric receptor complex.

Animal Model Products

miRNA for MS4A14 Gene

miRTarBase miRNAs that target MS4A14

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for MS4A14

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targets and HOMER Transcription for MS4A14 Gene

Localization for MS4A14 Gene

Subcellular locations from UniProtKB/Swiss-Prot for MS4A14 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for MS4A14 Gene COMPARTMENTS Subcellular localization image for MS4A14 gene
Compartment Confidence
plasma membrane 3
endoplasmic reticulum 1
mitochondrion 1
nucleus 1
peroxisome 1

Gene Ontology (GO) - Cellular Components for MS4A14 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with MS4A14: view

Pathways for MS4A14 Gene

SuperPathways for MS4A14 Gene

No Data Available

Interacting Proteins for MS4A14 Gene

Gene Ontology (GO) - Biological Process for MS4A14 Gene


No data available for Pathways by source for MS4A14 Gene

Transcripts for MS4A14 Gene

Unigene Clusters for MS4A14 Gene

Membrane-spanning 4-domains, subfamily A, member 14:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for MS4A14

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MS4A14 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b · 7c · 7d · 7e
SP1: - -
SP2: - -
SP3: - - -
SP4: - - -
SP5: - - - -

Relevant External Links for MS4A14 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MS4A14 Gene

mRNA expression in normal human tissues for MS4A14 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for MS4A14 Gene

This gene is overexpressed in Testis (20.8).

Protein differential expression in normal tissues for MS4A14 Gene

This gene is overexpressed in Heart (69.0).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for MS4A14 Gene

SOURCE GeneReport for Unigene cluster for MS4A14 Gene Hs.709736

genes like me logo Genes that share expressions with MS4A14: view

Expression partners for MS4A14 Gene

* - Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for MS4A14 Gene

Orthologs for MS4A14 Gene

This gene was present in the common ancestor of mammals.

Orthologs for MS4A14 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia MS4A14 35
  • 69.8 (n)
  • 52.07 (a)
MS4A14 36
  • 36 (a)
(Canis familiaris)
Mammalia MS4A14 35
  • 73.9 (n)
  • 55.2 (a)
MS4A14 36
  • 34 (a)
(Mus musculus)
Mammalia Ms4a14 16
(Monodelphis domestica)
Mammalia MS4A14 36
  • 29 (a)
(Pan troglodytes)
Mammalia MS4A14 36
  • 97 (a)
Species with no ortholog for MS4A14:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MS4A14 Gene

Gene Tree for MS4A14 (if available)
Gene Tree for MS4A14 (if available)

Paralogs for MS4A14 Gene

Paralogs for MS4A14 Gene

(2) SIMAP similar genes for MS4A14 Gene using alignment to 8 proteins:

genes like me logo Genes that share paralogs with MS4A14: view

Variants for MS4A14 Gene

Sequence variations from dbSNP and Humsavar for MS4A14 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs34211432 -- 60,410,832(+) TTGGG(-/T)TTTTT intron-variant
rs17154951 -- 60,414,949(+) CATAA(A/T)GCACT intron-variant
rs17154923 -- 60,401,994(+) ACCAC(A/G)GTAGT intron-variant
rs12292941 -- 60,407,061(+) ccagg(C/T)tggaa intron-variant
rs12281658 -- 60,400,835(+) cattt(A/C)taagc intron-variant

Structural Variations from Database of Genomic Variants (DGV) for MS4A14 Gene

Variant ID Type Subtype PubMed ID
esv2744569 CNV Deletion 23290073
esv2215205 CNV Deletion 18987734

Relevant External Links for MS4A14 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MS4A14 Gene

Disorders for MS4A14 Gene

Relevant External Links for MS4A14

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator

No disorders were found for MS4A14 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for MS4A14 Gene

Publications for MS4A14 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  4. New genetic associations detected in a host response study to hepatitis B vaccine. (PMID: 20237496) Davila S. … Seielstad M. (Genes Immun. 2010) 3
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4

Products for MS4A14 Gene

Sources for MS4A14 Gene

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