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Aliases for MS4A13 Gene

Aliases for MS4A13 Gene

  • Membrane Spanning 4-Domains A13 2 3
  • Membrane-Spanning 4-Domains, Subfamily A, Member 13 2 5
  • Testis-Expressed Transmembrane Protein 4 4

External Ids for MS4A13 Gene

Previous GeneCards Identifiers for MS4A13 Gene

  • GC00U921632
  • GC11U900699
  • GC11P060039
  • GC11P060282
  • GC11P056629

Summaries for MS4A13 Gene

GeneCards Summary for MS4A13 Gene

MS4A13 (Membrane Spanning 4-Domains A13) is a Protein Coding gene.

UniProtKB/Swiss-Prot for MS4A13 Gene

  • May be involved in signal transduction as a component of a multimeric receptor complex.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MS4A13 Gene

Genomics for MS4A13 Gene

Regulatory Elements for MS4A13 Gene

Enhancers for MS4A13 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around MS4A13 on UCSC Golden Path with GeneCards custom track

Genomic Location for MS4A13 Gene

Chromosome:
11
Start:
60,515,376 bp from pter
End:
60,543,424 bp from pter
Size:
28,049 bases
Orientation:
Plus strand

Genomic View for MS4A13 Gene

Genes around MS4A13 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MS4A13 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MS4A13 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MS4A13 Gene

Proteins for MS4A13 Gene

  • Protein details for MS4A13 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5J8X5-M4A13_HUMAN
    Recommended name:
    Membrane-spanning 4-domains subfamily A member 13
    Protein Accession:
    Q5J8X5
    Secondary Accessions:
    • B2RTS9
    • Q5J8X3
    • Q5J8X4

    Protein attributes for MS4A13 Gene

    Size:
    152 amino acids
    Molecular mass:
    17307 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for MS4A13 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for MS4A13 Gene

Proteomics data for MS4A13 Gene at MOPED

Post-translational modifications for MS4A13 Gene

No Post-translational modifications

Other Protein References for MS4A13 Gene

No data available for DME Specific Peptides for MS4A13 Gene

Domains & Families for MS4A13 Gene

Gene Families for MS4A13 Gene

Protein Domains for MS4A13 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for MS4A13 Gene

Graphical View of Domain Structure for InterPro Entry

Q5J8X5

UniProtKB/Swiss-Prot:

M4A13_HUMAN :
  • Belongs to the MS4A family.
Family:
  • Belongs to the MS4A family.
genes like me logo Genes that share domains with MS4A13: view

Function for MS4A13 Gene

Molecular function for MS4A13 Gene

UniProtKB/Swiss-Prot Function:
May be involved in signal transduction as a component of a multimeric receptor complex.

Phenotypes for MS4A13 Gene

genes like me logo Genes that share phenotypes with MS4A13: view

Animal Model Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MS4A13 Gene

Localization for MS4A13 Gene

Subcellular locations from UniProtKB/Swiss-Prot for MS4A13 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for MS4A13 Gene COMPARTMENTS Subcellular localization image for MS4A13 gene
Compartment Confidence
plasma membrane 3

No data available for Gene Ontology (GO) - Cellular Components for MS4A13 Gene

Pathways & Interactions for MS4A13 Gene

SuperPathways for MS4A13 Gene

No Data Available

Interacting Proteins for MS4A13 Gene

Gene Ontology (GO) - Biological Process for MS4A13 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MS4A13 Gene

Drugs & Compounds for MS4A13 Gene

No Compound Related Data Available

Transcripts for MS4A13 Gene

mRNA/cDNA for MS4A13 Gene

(3) REFSEQ mRNAs :
(5) Additional mRNA sequences :
(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for MS4A13 Gene

Membrane-spanning 4-domains, subfamily A, member 13:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for MS4A13 Gene

No ASD Table

Relevant External Links for MS4A13 Gene

GeneLoc Exon Structure for
MS4A13
ECgene alternative splicing isoforms for
MS4A13

Expression for MS4A13 Gene

mRNA expression in normal human tissues for MS4A13 Gene

mRNA differential expression in normal tissues according to GTEx for MS4A13 Gene

This gene is overexpressed in Testis (x53.0).

SOURCE GeneReport for Unigene cluster for MS4A13 Gene Hs.523704

genes like me logo Genes that share expression patterns with MS4A13: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MS4A13 Gene

Orthologs for MS4A13 Gene

This gene was present in the common ancestor of mammals.

Orthologs for MS4A13 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia MS4A13 35
  • 77.92 (n)
  • 62.25 (a)
MS4A13 36
  • 60 (a)
OneToOne
dog
(Canis familiaris)
Mammalia LOC100685813 35
  • 80.79 (n)
  • 72.19 (a)
MS4A13 36
  • 61 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Ms4a13 35
  • 74.88 (n)
  • 67.16 (a)
Ms4a13 16
Ms4a13 36
  • 44 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia MS4A13 35
  • 98.68 (n)
  • 96.71 (a)
MS4A13 36
  • 97 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Ms4a13-ps1 35
  • 73.33 (n)
  • 62.67 (a)
oppossum
(Monodelphis domestica)
Mammalia MS4A13 36
  • 12 (a)
OneToOne
Species with no ortholog for MS4A13:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MS4A13 Gene

ENSEMBL:
Gene Tree for MS4A13 (if available)
TreeFam:
Gene Tree for MS4A13 (if available)

Paralogs for MS4A13 Gene

No data available for Paralogs for MS4A13 Gene

Variants for MS4A13 Gene

Sequence variations from dbSNP and Humsavar for MS4A13 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs6591595 - 60,523,940(+) GTATC(C/T)GACTC intron-variant, nc-transcript-variant, reference, missense
rs55756397 - 60,518,091(+) GATTG(A/G)CATCT nc-transcript-variant, reference, missense
rs10736706 - 60,518,102(+) TTCAC(A/G)TTTTC nc-transcript-variant, reference, missense
rs750939 -- 60,540,566(-) TCACT(A/G)AATAA intron-variant
rs766110 -- 60,513,477(-) GCAAT(A/G)TCCAT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MS4A13 Gene

Variant ID Type Subtype PubMed ID
nsv337 CNV Insertion 18451855
esv267487 CNV Insertion 20981092
esv273867 CNV Insertion 20981092

Variation tolerance for MS4A13 Gene

Residual Variation Intolerance Score: 68.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.55; 30.07% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for MS4A13 Gene

HapMap Linkage Disequilibrium report
MS4A13

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MS4A13 Gene

Disorders for MS4A13 Gene

Relevant External Links for MS4A13

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MS4A13

No disorders were found for MS4A13 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MS4A13 Gene

Publications for MS4A13 Gene

  1. Genome-wide association study of a heart failure related metabolomic profile among African Americans in the Atherosclerosis Risk in Communities (ARIC) study. (PMID: 23934736) Yu B. … Boerwinkle E. (Genet. Epidemiol. 2013) 3 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for MS4A13 Gene

Sources for MS4A13 Gene

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