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Aliases for MS4A10 Gene

Aliases for MS4A10 Gene

  • Membrane-Spanning 4-Domains, Subfamily A, Member 10 2 3
  • CD20 Antigen-Like 7 3 4
  • CD20L7 3 4
  • MS4A9 3 4
  • Membrane-Spanning 4-Domains Subfamily A Member 10 3

External Ids for MS4A10 Gene

Previous GeneCards Identifiers for MS4A10 Gene

  • GC11P062951
  • GC11M062071
  • GC11P060333
  • GC11P060328
  • GC11P060309
  • GC11P060552
  • GC11P056899

Summaries for MS4A10 Gene

Entrez Gene Summary for MS4A10 Gene

  • Most MS4A genes, including MS4A10, encode proteins with at least 4 potential transmembrane domains and N- and C-terminal cytoplasmic domains encoded by distinct exons.[supplied by OMIM, Apr 2004]

GeneCards Summary for MS4A10 Gene

MS4A10 (Membrane-Spanning 4-Domains, Subfamily A, Member 10) is a Protein Coding gene.

UniProtKB/Swiss-Prot for MS4A10 Gene

  • May be involved in signal transduction as a component of a multimeric receptor complex

No data available for Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MS4A10 Gene

Genomics for MS4A10 Gene

Regulatory Elements for MS4A10 Gene

Genomic Location for MS4A10 Gene

60,785,348 bp from pter
60,801,305 bp from pter
15,958 bases
Plus strand

Genomic View for MS4A10 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MS4A10 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MS4A10 Gene

Proteins for MS4A10 Gene

  • Protein details for MS4A10 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Membrane-spanning 4-domains subfamily A member 10
    Protein Accession:
    Secondary Accessions:
    • B2RP45
    • Q96PG3

    Protein attributes for MS4A10 Gene

    267 amino acids
    Molecular mass:
    29747 Da
    Quaternary structure:
    No Data Available

neXtProt entry for MS4A10 Gene

Proteomics data for MS4A10 Gene at MOPED

Post-translational modifications for MS4A10 Gene

No Post-translational modifications

Other Protein References for MS4A10 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for MS4A10 Gene

Domains for MS4A10 Gene

Gene Families for MS4A10 Gene

Protein Domains for MS4A10 Gene

Suggested Antigen Peptide Sequences for MS4A10 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the MS4A family.
  • Belongs to the MS4A family.
genes like me logo Genes that share domains with MS4A10: view

Function for MS4A10 Gene

Molecular function for MS4A10 Gene

UniProtKB/Swiss-Prot Function:
May be involved in signal transduction as a component of a multimeric receptor complex

Gene Ontology (GO) - Molecular Function for MS4A10 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with MS4A10: view

Animal Model Products

miRNA for MS4A10 Gene

miRTarBase miRNAs that target MS4A10

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for MS4A10

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targets and HOMER Transcription for MS4A10 Gene

Localization for MS4A10 Gene

Subcellular locations from UniProtKB/Swiss-Prot for MS4A10 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for MS4A10 Gene COMPARTMENTS Subcellular localization image for MS4A10 gene
Compartment Confidence
plasma membrane 3
mitochondrion 1

Gene Ontology (GO) - Cellular Components for MS4A10 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with MS4A10: view

Pathways for MS4A10 Gene

SuperPathways for MS4A10 Gene

No Data Available

Interacting Proteins for MS4A10 Gene

Selected Interacting proteins: Q96PG2-M4A10_HUMAN for MS4A10 Gene via I2D

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for MS4A10 Gene


No data available for Pathways by source for MS4A10 Gene

Transcripts for MS4A10 Gene

mRNA/cDNA for MS4A10 Gene

(4) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(2) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for MS4A10 Gene

Membrane-spanning 4-domains, subfamily A, member 10:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for MS4A10

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MS4A10 Gene

No ASD Table

Relevant External Links for MS4A10 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MS4A10 Gene

mRNA expression in normal human tissues for MS4A10 Gene

mRNA differential expression in normal tissues according to GTEx for MS4A10 Gene

This gene is overexpressed in Small Intestine - Terminal Ileum (50.9).

Protein differential expression in normal tissues for MS4A10 Gene

This gene is overexpressed in Fetal Brain (62.6).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for MS4A10 Gene

SOURCE GeneReport for Unigene cluster for MS4A10 Gene Hs.591956

genes like me logo Genes that share expressions with MS4A10: view

Expression partners for MS4A10 Gene

* - Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for MS4A10 Gene

Orthologs for MS4A10 Gene

This gene was present in the common ancestor of mammals.

Orthologs for MS4A10 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia MS4A10 35
  • 72.01 (n)
  • 60.76 (a)
MS4A10 36
  • 58 (a)
(Mus musculus)
Mammalia Ms4a10 35
  • 66.52 (n)
  • 55.6 (a)
Ms4a10 16
Ms4a10 36
  • 48 (a)
(Pan troglodytes)
Mammalia MS4A10 35
  • 99.25 (n)
  • 98.5 (a)
MS4A10 36
  • 98 (a)
(Rattus norvegicus)
Mammalia Ms4a10 35
  • 68.63 (n)
  • 60.63 (a)
(Canis familiaris)
Mammalia MS4A10 36
  • 62 (a)
Species with no ortholog for MS4A10:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MS4A10 Gene

Gene Tree for MS4A10 (if available)
Gene Tree for MS4A10 (if available)

Paralogs for MS4A10 Gene

No data available for Paralogs for MS4A10 Gene

Variants for MS4A10 Gene

Sequence variations from dbSNP and Humsavar for MS4A10 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs474435 -- 60,790,220(+) AGATC(C/T)GGTCC intron-variant
rs503358 -- 60,794,965(+) caggc(A/G)tgagc intron-variant
rs510570 -- 60,799,354(-) CAAAA(A/G)TCCTG intron-variant
rs514147 -- 60,797,205(+) AACTG(A/G)GGCCC intron-variant
rs523483 -- 60,784,908(+) agttt(G/T)gctta upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MS4A10 Gene

Variant ID Type Subtype PubMed ID
nsv897598 CNV Loss 21882294
esv273941 CNV Insertion 20981092

Relevant External Links for MS4A10 Gene

HapMap Linkage Disequilibrium report
Human Gene Mutation Database (HGMD)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MS4A10 Gene

Disorders for MS4A10 Gene

No disorders were found for MS4A10 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for MS4A10 Gene

Publications for MS4A10 Gene

  1. Structural organization of the human MS4A gene cluster on chromosome 11q12. (PMID: 11486273) Liang Y. … Tedder T.F. (Immunogenetics 2001) 2 3 4
  2. Identification of a CD20-, Fc-epsilon-RI-beta-, and HTm4-related gene family: sixteen new MS4A family members expressed in human and mouse. (PMID: 11401424) Liang Y. … Tedder T.F. (Genomics 2001) 2 3
  3. Identification of a new multigene four-transmembrane family (MS4A) related to CD20, HTm4 and beta subunit of the high-affinity IgE receptor. (PMID: 11245982) Ishibashi K. … Imai M. (Gene 2001) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4

Products for MS4A10 Gene

Sources for MS4A10 Gene

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