Aliases for MS4A1 Gene
External Ids for MS4A1 Gene
Previous Symbols for MS4A1 Gene
This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This gene encodes a B-lymphocyte surface molecule which plays a role in the development and differentiation of B-cells into plasma cells. This family member is localized to 11q12, among a cluster of family members. Alternative splicing of this gene results in two transcript variants which encode the same protein. [provided by RefSeq, Jul 2008]
GeneCards Summary for MS4A1 Gene
MS4A1 (Membrane-Spanning 4-Domains, Subfamily A, Member 1) is a Protein Coding gene. Diseases associated with MS4A1 include immunodeficiency, common variable, 5 and membranous glomerulonephritis. Among its related pathways are PI-3K cascade and Immune response Fc epsilon RI pathway.
UniProtKB/Swiss-Prot for MS4A1 Gene
This protein may be involved in the regulation of B-cell activation and proliferation