MRRFP1 Gene
pseudogene GIFtS: 20
GCID: GC0XM122249
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mitochondrial ribosome recycling factor pseudogene 1(Previous name: mitochondrial ribosome recycling factor pseudogene )
(Previous symbol: MRRFP)
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Aliases
for MRRFP1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Mitochondrial Ribosome Recycling Factor Pseudogene 11 2 | | MRRFP1 2 | | Mitochondrial Ribosome Recycling Factor Pseudogene1 |
Export aliases for MRRFP1 gene to outside databasesPrevious GC identifer: GC0XM111632 |
Summaries
for MRRFP1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for MRRFP1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for MRRFP1
Other transcription factors
Search SABiosciences Chromatin IP Primers for MRRFP1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MRRFP1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: Xq25 Ensembl cytogenetic band: Xq25 HGNC cytogenetic band: Xq25MRRFP1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome X GeneLoc Exon Structure GeneLoc location for GC0XM122249: view genomic region
(about GC identifiers)
Start:
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122,249,960 bp from pter |
End:
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122,251,679 bp from pter |
Size:
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1,720 bases |
Orientation:
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minus strand |
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Proteins
for MRRFP1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/TrEMBL: Q4TT42 (See
protein sequence)Recommended Name: Protein MRRFP1 Size: 262 amino acids; 29217 Da
Caution: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered aspreliminary dataMRRFP1 Protein expression data from MOPED and PaxDb: About this image 
ENSEMBL proteins: ENSP00000387841
Human Recombinant Protein Products:
MRRFP1 Antibody Products:
Assay Products for MRRFP1: |
Protein
Domains /
Families
for MRRFP1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
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MRRFP1 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q4TT42ProtoNet protein and cluster: Q4TT42 1 Blocks protein family: IPB002661 Ribosome recycling factor
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Function
for MRRFP1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
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Pathways & Interactions
for MRRFP1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MRRFP1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/25 Interacting proteins for MRRFP1 (ENSP000003878414) via UniProtKB, MINT, STRING, and/or I2D (see all 25)About this table
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
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| GO:0006412 | translation |
-- | -- |
MRRFP1 for ontologies About GeneDecksing
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Drugs & Compounds
for MRRFP1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for MRRFP1
Search CenterWatch for drugs/clinical trials and news about MRRFP1 
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Transcripts
for MRRFP1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
1 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000435941
GeneLoc Exon Structure
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Expression
for MRRFP1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| MRRFP1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See MRRFP1 Protein Expression from SPIRE MOPED and PaxDB SABiosciences Custom PCR Arrays for MRRFP1
Primer
Products: |  | Browse OriGene genome-wide validated SYBR primer pairs
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat MRRFP1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MRRFP1 | | | Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MRRFP1 |
Orthologs
for MRRFP1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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This gene was present in the last universal common ancestor (LUCA).
Orthologs for MRRFP1 gene from 6/20 species (see all 20) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
MRRF6 |
Uncharacterized protein |
57(a) |
1 → many |
17(9455298-9465338) |
zebrafish
(Danio rerio) |
Actinopterygii |
mrrf6 |
mitochondrial ribosome recycling factor |
51(a) |
1 → many |
10(9395535-9436845) |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG44476 |
-- |
30(a) |
1 → many |
3L(9357450-9358340) |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
AT3G018006cpRRF6 |
ribosome-recycling factor |
21(a)17(a) |
1 ↔ manypossible ortholog |
3(285871-287950) 3(23342582-23344773) |
rice
(Oryza sativa) |
Liliopsida |
---- |
ribosome recycling factor, putative, expressed |
20(a)16(a) |
1 ↔ manypossible ortholog |
4(24320405-24323263) 7(23002387-23007504) |
E. coli
(Escherichia coli) |
Gamma proteobacteria |
frr6 |
ribosome recycling factor |
26(a) |
1 → many |
Chromosome(192872-193429) |
ENSEMBL Gene Tree for MRRFP1 (if available)
TreeFam Gene Tree for MRRFP1 (if available) |
Paralogs
for MRRFP1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for MRRFP1 gene
- MRRF2
1 SIMAP similar gene for MRRFP1 using alignment to 1 protein entry: Q4TT42_HUMAN:MRRF
MRRFP1 for paralogs About GeneDecksing
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Genomic Variants
for MRRFP1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
| | SABiosciences Cancer Mutation PCR Assays |
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Disorders
/ Diseases
for MRRFP1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
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MRRFP1 for disorders About GeneDecksing
3  diseases for MRRFP1: About MalaCardspneumonia tuberculosis mycobacterium tuberculosis
Export disorders for MRRFP1 gene to outside databases
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Publications
for MRRFP1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
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PubMed article for MRRFP1 gene integrated from 9 sources:
(articles sorted by number of sources associating them with MRRFP1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
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External Searches for MRRFP1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing MRRFP1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
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Other Databases showing MRRFP1 gene
(According to HUGE)
About This Section
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Specialized Databases showing MRRFP1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
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About This Section
| Patent Information for MRRFP1 gene:
Search GeneIP for patents involving MRRFP1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for MRRFP1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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|  | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat MRRFP1 | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MRRFP1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MRRFP1 | | | Search QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MRRFP1 | | | Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MRRFP1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MRRFP1 |
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| | | | Search Tocris compounds for MRRFP1 |
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 | | | | |  |  |  | | | | Search ThermoFisher Antibodies for MRRFP1 |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat MRRFP1 |
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