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MRPS9 Gene

protein-coding   GIFtS: 56
GCID: GC02P105654

Mitochondrial Ribosomal Protein S9

Microbiology & Infectious Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Mitochondrial Ribosomal Protein S91 2     28S Ribosomal Protein S91
MRP-S92 3     mitochondrial1
RPMS92 3     28S Ribosomal Protein S9, Mitochondrial2
S9mt2 3     

External Ids:    HGNC: 145011   Entrez Gene: 649652   Ensembl: ENSG000001359727   OMIM: 6119755   UniProtKB: P829333   

Export aliases for MRPS9 gene to outside databases

Previous GC identifers: GC02P103518 GC02P104107 GC02P105259 GC02P105275 GC02P105113 GC02P105020 GC02P099424


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for MRPS9 Gene:
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the
mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit.
They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is
reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain
a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and
sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a
28S subunit protein. (provided by RefSeq, Jul 2008)

GeneCards Summary for MRPS9 Gene:
MRPS9 (mitochondrial ribosomal protein S9) is a protein-coding gene. Diseases associated with MRPS9 include brain cancer, and parkinson's disease. GO annotations related to this gene include structural constituent of ribosome.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000002.12  NC_018913.2  NT_005403.18  
Regulatory elements:
   Regulatory transcription factor binding sites in the MRPS9 gene promoter:
         TBP   USF1   LHX3b/Lhx3b   AP-1   AML1a   Nkx2-5   PPAR-gamma1   TFIID   LHX3a/Lhx3a   PPAR-gamma2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMRPS9 promoter sequence
   Search Chromatin IP Primers for MRPS9

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MRPS9


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q12.1   Ensembl cytogenetic band:  2q12.1   HGNC cytogenetic band: 2q12.1

MRPS9 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MRPS9 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02P105654:  view genomic region     (about GC identifiers)

Start:
105,654,441 bp from pter      End:
105,716,418 bp from pter
Size:
61,978 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: RT09_HUMAN, P82933 (See protein sequence)
Recommended Name: 28S ribosomal protein S9, mitochondrial precursor  
Size: 396 amino acids; 45835 Da
Subunit: Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30
distinct proteins (By similarity)
Secondary accessions: Q6PG40

Explore the universe of human proteins at neXtProt for MRPS9: NX_P82933

Explore proteomics data for MRPS9 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys119
  • Modification sites at PhosphoSitePlus

  • See MRPS9 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_872578.1  
    ENSEMBL proteins: 
     ENSP00000258455   ENSP00000388885  

    MRPS9 Human Recombinant Protein Products:

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    Novus Biologicals MRPS9 Protein
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    Cloud-Clone Corp. Proteins for MRPS9

    MRPS9 Antibody Products:

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    Novus Biologicals MRPS9 Antibodies
    Abcam antibodies for MRPS9
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    Search ThermoFisher Antibodies for MRPS9
    LSBio Antibodies in human, mouse, rat for MRPS9

    MRPS9 Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for MRPS9
    Cloud-Clone Corp. CLIAs for MRPS9


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    MRPS: Mitochondrial ribosomal proteins / small subunits

    4 InterPro protein domains:
     IPR020574 Ribosomal_S9_CS
     IPR020568 Ribosomal_S5_D2-typ_fold
     IPR000754 Ribosomal_S9
     IPR014721 Ribosomal_S5_D2-typ_fold_subgr

    Graphical View of Domain Structure for InterPro Entry P82933

    ProtoNet protein and cluster: P82933

    1 Blocks protein domain: IPB000754 Ribosomal protein S9

    UniProtKB/Swiss-Prot: RT09_HUMAN, P82933
    Similarity: Belongs to the ribosomal protein S9P family


    MRPS9 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003735structural constituent of ribosome IEA--
    GO:0005515protein binding IPI--
    GO:0044822poly(A) RNA binding IDA--
         
    MRPS9 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for MRPS9
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for MRPS9

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for MRPS9
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for MRPS9

    miRNA
    Products:
        
    miRTarBase miRNAs that target MRPS9:
    hsa-mir-193b-3p (MIRT016354)

    Block miRNA regulation of human, mouse, rat MRPS9 using miScript Target Protectors
    3 qRT-PCR Assays for microRNAs that regulate MRPS9:
    hsa-miR-520d-5p hsa-miR-524-5p hsa-miR-548c-3p
    SwitchGear 3'UTR luciferase reporter plasmidMRPS9 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for MRPS9
    Predesigned siRNA for gene silencing in human, mouse, rat MRPS9

    Gene Editing
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    DNA2.0 Custom Protein Engineering Service for MRPS9

    Clone
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    OriGene clones in human, mouse for MRPS9 (see all 7)
    OriGene ORF clones in mouse, rat for MRPS9
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: MRPS9 (NM_182640)
    Sino Biological Human cDNA Clone for MRPS9
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MRPS9
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MRPS9

    Cell Line
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MRPS9


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    RT09_HUMAN, P82933: Mitochondrion
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    mitochondrion5
    nucleus3
    chloroplast2
    cytosol2
    endoplasmic reticulum1

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005730nucleolus IDA--
    GO:0005739mitochondrion IDA--
    GO:0005763mitochondrial small ribosomal subunit NAS11279123
    GO:0005840ribosome ----

    MRPS9 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for MRPS9 About    
    See pathways by source

    SuperPathContained pathways About
    1CFTR translational fidelity class I mutations
    Ribosome0.54

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways




    1 Kegg Pathway  (Kegg details for MRPS9):
        Ribosome


    MRPS9 for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for MRPS9
    Interactions:

        Search GeneGlobe Interaction Network for MRPS9

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for MRPS9 (P829331, 2, 3 ENSP000002584554) via UniProtKB, MINT, STRING, and/or I2D (see all 484)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ICT1Q141972, 3, ENSP000003015854MINT-8079030 I2D: score=1 STRING: ENSP00000301585
    HAP1P542572, 3MINT-64675 I2D: score=4 
    RBM4BQ9BQ042, 3MINT-64676 I2D: score=4 
    CCNDBP1O952732, 3, ENSP000003002134MINT-64674 I2D: score=4 STRING: ENSP00000300213
    ESR1P033723, ENSP000002062494I2D: score=1 STRING: ENSP00000206249
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006412translation IEA--
    GO:0042769DNA damage response, detection of DNA damage NAS15300802
    GO:0043043peptide biosynthetic process IC11279123

    MRPS9 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for MRPS9 (RT09)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for MRPS9 gene: 
    NM_182640.2  

    Unigene Cluster for MRPS9:

    Mitochondrial ribosomal protein S9
    Hs.590900  [show with all ESTs]
    Unigene Representative Sequence: NM_182640
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000258455(uc002tcn.4) ENST00000413583 ENST00000472220
    Congresses - knowledge worth sharing:
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat MRPS9 using miScript Target Protectors
    3 qRT-PCR Assays for microRNAs that regulate MRPS9:
    hsa-miR-520d-5p hsa-miR-524-5p hsa-miR-548c-3p
    SwitchGear 3'UTR luciferase reporter plasmidMRPS9 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for MRPS9
    Predesigned siRNA for gene silencing in human, mouse, rat MRPS9
    Clone
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    OriGene clones in human, mouse for MRPS9 (see all 7)
    OriGene ORF clones in mouse, rat for MRPS9
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: MRPS9 (NM_182640)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MRPS9
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MRPS9
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for MRPS9
    OriGene qSTAR qPCR primer pairs in human, mouse for MRPS9
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat MRPS9
      QuantiTect SYBR Green Assays in human, mouse, rat MRPS9
      QuantiFast Probe-based Assays in human, mouse, rat MRPS9

    Additional mRNA sequence: 

    AK001451.1 AK130078.1 BC036575.1 BC047784.1 BC057240.1 

    10 DOTS entries:

    DT.313104  DT.75130767  DT.92424517  DT.91968378  DT.95271594  DT.98083396  DT.121020495  DT.435217 
    DT.445573  DT.91651679 

    Selected AceView cDNA sequences (see all 121):

    AI925905 AW771571 AI762358 CR602949 AK001451 AI972638 AA306466 BU069179 
    BU156446 AA565885 BE887338 BM453425 AI636224 BC057240 AU128875 AI829434 
    AV718165 BC047784 BM849162 BQ646420 BQ271786 NM_182640 AK130078 AI671555 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    MRPS9 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AGGGCAGTAC
    MRPS9 Expression
    About this image


    MRPS9 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 8) fully expand
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Cerebral Cortex
     
     Trophoblast (Extraembryonic Tissues)
             Trophoblast Cells Trophoblast
     
     Ovary (Reproductive System)
             Oviduct
     
     Pancreas (Endocrine System)
             Islets of Langerhans
     
     Testis (Reproductive System)
             Leydig Cells Testis Interstitium
    MRPS9 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    MRPS9 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.590900
        Custom PCR Arrays for MRPS9
    Primer
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    OriGene qPCR primer pairs and template standards for MRPS9
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    QuantiFast Probe-based Assays in human, mouse, rat MRPS9
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MRPS9

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for MRPS9 gene from Selected species (see all 17)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Mrps91 , 5 mitochondrial ribosomal protein S91, 5 80.34(n)1
    78.46(a)1
      1 (21.62 cM)5
    695271  NM_023514.41  NP_076003.31 
     428512335 
    chicken
    (Gallus gallus)
    Aves MRPS91 mitochondrial ribosomal protein S9 71.09(n)
    68.56(a)
      418723  NM_001277757.1  NP_001264686.1 
    lizard
    (Anolis carolinensis)
    Reptilia MRPS96
    mitochondrial ribosomal protein S9
    62(a)
    1 ↔ 1
    GL343243.1(6804-46943)
    African clawed frog
    (Xenopus laevis)
    Amphibia BU899800.12   -- 74.88(n)    BU899800.1 
    zebrafish
    (Danio rerio)
    Actinopterygii mrps91 mitochondrial ribosomal protein S9 59.49(n)
    58.27(a)
      751681  NM_001045396.1  NP_001038861.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta mRpS91 , 3 protein biosynthesis structural
    constituent of more3
    mitochondrial ribosomal protein S91
    40(a)3
    52.27(n)1
    46.83(a)1
      84E43
    409321  NM_079546.21  NP_524270.21 
    worm
    (Caenorhabditis elegans)
    Secernentea F09G8.33
    mrps-91
    mrps-91 33(a)3
    44.9(n)1
    36.56(a)1
      III(8337798-8339467)3
    1842671  NM_066414.51  NP_498815.11 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes MRPS9(YBR146W)4 Mitochondrial ribosomal protein of the small subunit   --   2(535260-536096) 852443  NP_009704.1 


    ENSEMBL Gene Tree for MRPS9 (if available)
    TreeFam Gene Tree for MRPS9 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for MRPS9 (see all 1370)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs118956181,2
    C,F,H--105652511(+) atcacC/Ttgagg 1 -- us2k1 tfbs31Minor allele frequency- T:0.50NA 4
    rs1809511691,2
    --105652516(+) CTGAGC/GTCAGG 1 -- us2k10--------
    rs1850619461,2
    --105652591(+) GGGCAC/TGGTGG 1 -- us2k10--------
    rs1902601251,2
    --105652598(+) GTGGTA/GGGCAC 1 -- us2k10--------
    rs1812318031,2
    --105652621(+) CTACTC/TGGGAG 1 -- us2k10--------
    rs67549561,2
    C,F,A,H--105652687(+) tcacaC/Tcactg 1 -- us2k18Minor allele frequency- T:0.44NA WA CSA 16
    rs1399851001,2
    C--105652791(+) CATCCA/GTTGAC 1 -- us2k10--------
    rs1861624801,2
    --105653101(+) ATGGAA/TGACAA 1 -- us2k10--------
    rs67109841,2
    C,F,A,H--105653102(+) tggatG/Aacaaa 1 -- us2k16Minor allele frequency- A:0.39NA WA CSA 129
    rs1123650751,2
    F--105653481(+) GATATC/ATTTTG 1 -- us2k12Minor allele frequency- A:0.04CSA WA 120

    HapMap Linkage Disequilibrium report for MRPS9 (105654441 - 105716418 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for MRPS9 (see all 11):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2720479CNV Deletion23290073
    esv2720475CNV Deletion23290073
    esv2720478CNV Deletion23290073
    esv2720476CNV Deletion23290073
    dgv86e180CNV Deletion20482838
    esv2720477CNV Deletion23290073
    esv2720474CNV Deletion23290073
    esv2663750CNV Deletion23128226
    esv27425CNV Loss19812545
    dgv85e180CNV Loss20482838

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing MRPS9
    DNA2.0 Custom Variant and Variant Library Synthesis for MRPS9

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 611975    OMIM disorders: --

    12 diseases for MRPS9:    
    About MalaCards
    brain cancer    parkinson's disease    pneumonia    tonsillitis
    tuberculosis    retinitis    thyroiditis    breast cancer
    cerebritis    malaria    endotheliitis    prostatitis


    MRPS9 for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015
    Genetic Association Database (GAD): MRPS9
    Human Genome Epidemiology (HuGE) Navigator: MRPS9 (1 document)

    Export disorders for MRPS9 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for MRPS9 gene, integrated from 10 sources (see all 30):
    (articles sorted by number of sources associating them with MRPS9)
        Utopia: connect your pdf to the dynamic
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    1. The small subunit of the mammalian mitochondrial ribosome: identification of the full complement of ribosomal proteins present. (PubMed id 11279123)1, 2, 3 Koc E.C.... Spremulli L.L. (J. Biol. Chem. 2001)
    2. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (PLoS ONE 2010)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS. (PubMed id 23455922)1 Varjosalo M....Superti-Furga G. (Nat. Methods 2013)
    5. The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells. (PubMed id 23667531)1 Cox J.L....Rizzino A. (PLoS ONE 2013)
    6. The HECT type ubiquitin ligase NEDL2 is degraded by anaphase-promoting complex/cyclosome (APC/C)-Cdh1, and its tight regulation maintains the metaphase to anaphase transition. (PubMed id 24163370)1 Lu L....Zhang L. (J. Biol. Chem. 2013)
    7. p32/gC1qR is indispensable for fetal development and mitochondrial translation: importance of its RNA-binding ability. (PubMed id 22904065)1 Yagi M....Kang D. (Nucleic Acids Res. 2012)
    8. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    9. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
    10. Global landscape of HIV-human protein complexes. (PubMed id 22190034)1 JAoger S....Krogan N.J. (Nature 2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 64965 HGNC: 14501 AceView: MRPS9 Ensembl:ENSG00000135972 euGenes: HUgn64965
    ECgene: MRPS9 Kegg: 64965 H-InvDB: MRPS9

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for MRPS9 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for MRPS9 gene:
    Search GeneIP for patents involving MRPS9

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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