MRPS9 Gene
protein-coding GIFtS: 48
GCID: GC02P105654
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mitochondrial ribosomal protein S9
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Aliases
for MRPS9 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Mitochondrial Ribosomal Protein S91 2 | | MRP-S91 2 3 | | RPMS91 2 3 | | S9mt1 2 3 | | 28S Ribosomal Protein S9, Mitochondrial2 |
Export aliases for MRPS9 gene to outside databasesPrevious GC identifers: GC02P103518 GC02P104107 GC02P105259 GC02P105275 GC02P105113 GC02P105020 GC02P099424 |
Summaries
for MRPS9 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for MRPS9:
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within themitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. Theyhave an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed.Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA.Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes inbiochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein.(provided by RefSeq, Jul 2008)
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Genomic Views
for MRPS9 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000002.11 NC_018913.1 NT_022171.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the MRPS9 gene promoter:
TBP USF1 LHX3b/Lhx3b AP-1 AML1a Nkx2-5 PPAR-gamma1 TFIID LHX3a/Lhx3a PPAR-gamma2
Other transcription factors
Search SABiosciences Chromatin IP Primers for MRPS9
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MRPS9 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 2q12.1 Ensembl cytogenetic band: 2q12.1 HGNC cytogenetic band: 2q12.1MRPS9 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 2 GeneLoc Exon Structure GeneLoc location for GC02P105654: view genomic region
(about GC identifiers)
Start:
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105,654,441 bp from pter |
End:
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105,716,418 bp from pter |
Size:
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61,978 bases |
Orientation:
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plus strand |
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Proteins
for MRPS9 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: RT09_HUMAN, P82933 (See
protein sequence)Recommended Name: 28S ribosomal protein S9, mitochondrial precursor Size: 396 amino acids; 45835 Da
Subunit: Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30 distinctproteins (By similarity)
Subcellular location: Mitochondrion
Secondary accessions: Q6PG40Explore the universe of human proteins at neXtProt for MRPS9: NX_P82933
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P82933
MRPS9 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_872578.1
ENSEMBL proteins: ENSP00000258455 ENSP00000388885
Human Recombinant Protein Products for MRPS9:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
MRPS9 for ontologies About GeneDecksing
MRPS9 Antibody Products:
Assay Products for MRPS9: |
Protein
Domains /
Families
for MRPS9 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
MRPS9 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P82933ProtoNet protein and cluster: P82933 1 Blocks protein family: IPB000754 Ribosomal protein S9
UniProtKB/Swiss-Prot: RT09_HUMAN, P82933Similarity: Belongs to the ribosomal protein S9P family |
Function
for MRPS9 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003735 | structural constituent of ribosome |
IEA | -- | | GO:0005515 | protein binding |
IPI | -- |
MRPS9 for ontologies About GeneDecksing
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MRPS9 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MRPS9 (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: MRPS9 (NM_182640) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MRPS9 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MRPS9 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MRPS9 |
|
Pathways & Interactions
for MRPS9 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MRPS9
STRING Interaction
Network Preview (showing 5 interactants - click image to see 13)
5/252 Interacting proteins for MRPS9 (P829331, 2, 3 ENSP000002584554) via UniProtKB, MINT, STRING, and/or I2D (see all 252)About this table
Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table
MRPS9 for ontologies About GeneDecksing
|
Drugs & Compounds
for MRPS9 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for MRPS9
Search CenterWatch for drugs/clinical trials and news about MRPS9 / RT09
|
Transcripts
for MRPS9 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for MRPS9 gene: NM_182640.2 Unigene Cluster for MRPS9: Mitochondrial ribosomal protein S9 Hs.590900 [show with all ESTs]Unigene Representative Sequence: NM_1826403 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000258455(uc002tcn.4) ENST00000413583 ENST00000472220
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MRPS9 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MRPS9 (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: MRPS9 (NM_182640) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MRPS9 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MRPS9 |
Additional cDNA sequence: AK001451.1 AK130078.1 BC036575.1 BC047784.1 BC057240.1 10 DOTS entries: DT.313104 DT.75130767 DT.92424517 DT.91968378 DT.95271594 DT.98083396 DT.121020495 DT.435217 DT.445573 DT.91651679 24/121 AceView cDNA sequences (see all 121): AA565885 BE887338 BM453425 AA306466 AI636224 BU156446 NM_182640 AI972638 AK130078 BQ271786 BC047784 AV718165 AI829434 AW771571 AK001451 CR602949 AI925905 AI762358 BU069179 AU128875 BC057240 BM849162 BQ646420 AI358295
GeneLoc Exon Structure
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Expression
for MRPS9 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| MRPS9 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AGGGCAGTAC
About this image
See MRPS9 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for MRPS9
SOURCE GeneReport for Unigene cluster: Hs.590900
SABiosciences Custom PCR Arrays for MRPS9
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MRPS9
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat MRPS9 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MRPS9 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MRPS9 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MRPS9 |
Orthologs
for MRPS9 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the last universal common ancestor (LUCA).
Orthologs for MRPS9 gene from 10/34 species (see all 34) About this table
ENSEMBL Gene Tree for MRPS9 (if available)
TreeFam Gene Tree for MRPS9 (if available) |
Paralogs
for MRPS9 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for MRPS9 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 2 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for MRPS9 (105654441 - 105716418 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 3 variations for MRPS9
2 CNVs: 58900 68100
1 Indel: 34319 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MRPS9 |
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Disorders
/ Diseases
for MRPS9 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
MRPS9 for disorders About GeneDecksing
OMIM gene information: 611975
OMIM disorders: --
5  diseases for MRPS9: About MalaCardsparkinson's disease pneumonia tuberculosis malaria
mycobacterium tuberculosis
Human Genome Epidemiology (HuGE) Navigator: MRPS9 (1 document)
Export disorders for MRPS9 gene to outside databases
|
Publications
for MRPS9 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for MRPS9 gene, integrated from 9 sources (see all 23):
(articles sorted by number of sources associating them with MRPS9) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The small subunit of the mammalian mitochondrial ribosome: identification of the full complement of ribosomal proteins present. (PubMed id 11279123)1, 2, 3 Koc E.C.... Spremulli L.L. (2001)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
- Global landscape of HIV-human protein complexes. (PubMed id 22190034)1 Jager S....Krogan N.J. (2012)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- Identification of proteins associated with ligand-acti vated estrogen receptor a in human breast cancer cell nuclei by tandem affinity purification and nano LC-MS/MS. (PubMed id 21182205)1 Tarallo R....Weisz A. (2011)
- Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
- Global analysis of lysine ubiquitination by ubiquitin remnant immunoaffinity profiling. (PubMed id 20639865)1 Xu G....Jaffrey S.R. (2010)
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External Searches for MRPS9 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
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Genome Databases showing MRPS9 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing MRPS9 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing MRPS9 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for MRPS9 | Pharmacogenomics, SNPs, Pathways |
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| | |
About This Section
| Patent Information for MRPS9 gene:
Search GeneIP for patents involving MRPS9
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for MRPS9 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for MRPS9 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MRPS9 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MRPS9 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for MRPS9 | | OriGene 3'-UTR Clone for MRPS9 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MRPS9 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MRPS9 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for MRPS9 | | OriGene Custom Protein Services for MRPS9 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat MRPS9 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MRPS9 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MRPS9 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MRPS9 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MRPS9 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MRPS9 |
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 | | | MRPS9 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MRPS9 |
|  |  |  |  | | | | Search ThermoFisher Antibodies for MRPS9 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MRPS9 |
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