Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MRPS9 Gene

Aliases for MRPS9 Gene

  • Mitochondrial Ribosomal Protein S9 2 3
  • MRP-S9 3 4
  • RPMS9 3 4
  • S9mt 3 4
  • 28S Ribosomal Protein S9, Mitochondrial 3
  • 28S Ribosomal Protein S9 2
  • Mitochondrial 2

External Ids for MRPS9 Gene

Previous GeneCards Identifiers for MRPS9 Gene

  • GC02P103518
  • GC02P104107
  • GC02P105259
  • GC02P105275
  • GC02P105113
  • GC02P105654
  • GC02P099424

Summaries for MRPS9 Gene

Entrez Gene Summary for MRPS9 Gene

  • Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. [provided by RefSeq, Jul 2008]

GeneCards Summary for MRPS9 Gene

MRPS9 (Mitochondrial Ribosomal Protein S9) is a Protein Coding gene. Among its related pathways are CFTR translational fidelity (class I mutations). GO annotations related to this gene include structural constituent of ribosome.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MRPS9 Gene

Genomics for MRPS9 Gene

Regulatory Elements for MRPS9 Gene

Genomic Location for MRPS9 Gene

Start:
105,037,983 bp from pter
End:
105,099,960 bp from pter
Size:
61,978 bases
Orientation:
Plus strand

Genomic View for MRPS9 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MRPS9 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MRPS9 Gene

Proteins for MRPS9 Gene

  • Protein details for MRPS9 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P82933-RT09_HUMAN
    Recommended name:
    28S ribosomal protein S9, mitochondrial
    Protein Accession:
    P82933
    Secondary Accessions:
    • Q6PG40

    Protein attributes for MRPS9 Gene

    Size:
    396 amino acids
    Molecular mass:
    45835 Da
    Quaternary structure:
    • Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30 distinct proteins.

neXtProt entry for MRPS9 Gene

Proteomics data for MRPS9 Gene at MOPED

Post-translational modifications for MRPS9 Gene

  • Ubiquitination at Lys119
  • Modification sites at PhosphoSitePlus

Other Protein References for MRPS9 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for MRPS9 Gene

Domains for MRPS9 Gene

Gene Families for MRPS9 Gene

HGNC:
  • MRPS :Mitochondrial ribosomal proteins / small subunits

Suggested Antigen Peptide Sequences for MRPS9 Gene

Graphical View of Domain Structure for InterPro Entry

P82933

UniProtKB/Swiss-Prot:

RT09_HUMAN :
  • P82933
Family:
  • Belongs to the ribosomal protein S9P family.
genes like me logo Genes that share domains with MRPS9: view

Function for MRPS9 Gene

Gene Ontology (GO) - Molecular Function for MRPS9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003735 structural constituent of ribosome IEA --
GO:0005515 protein binding IPI 22190034
GO:0044822 poly(A) RNA binding IDA 22681889
genes like me logo Genes that share ontologies with MRPS9: view

Animal Model Products

CRISPR Products

miRNA for MRPS9 Gene

miRTarBase miRNAs that target MRPS9

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for MRPS9

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for MRPS9 Gene

Localization for MRPS9 Gene

Subcellular locations from UniProtKB/Swiss-Prot for MRPS9 Gene

Mitochondrion.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for MRPS9 Gene COMPARTMENTS Subcellular localization image for MRPS9 gene
Compartment Confidence
mitochondrion 5
nucleus 3
chloroplast 2
cytosol 2
endoplasmic reticulum 1

Gene Ontology (GO) - Cellular Components for MRPS9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005730 nucleolus IDA --
GO:0005739 mitochondrion IDA --
GO:0005743 mitochondrial inner membrane TAS --
GO:0005763 mitochondrial small ribosomal subunit NAS 11279123
GO:0005840 ribosome --
genes like me logo Genes that share ontologies with MRPS9: view

Pathways for MRPS9 Gene

SuperPathways for MRPS9 Gene

Superpath Contained pathways
1 CFTR translational fidelity (class I mutations)
.54
genes like me logo Genes that share pathways with MRPS9: view

Pathways by source for MRPS9 Gene

1 KEGG pathway for MRPS9 Gene

Gene Ontology (GO) - Biological Process for MRPS9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006412 translation --
GO:0006996 organelle organization TAS --
GO:0032543 mitochondrial translation TAS --
GO:0042769 DNA damage response, detection of DNA damage NAS 15300802
GO:0070124 mitochondrial translational initiation TAS --
genes like me logo Genes that share ontologies with MRPS9: view

Transcripts for MRPS9 Gene

Unigene Clusters for MRPS9 Gene

Mitochondrial ribosomal protein S9:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for MRPS9

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MRPS9 Gene

No ASD Table

Relevant External Links for MRPS9 Gene

GeneLoc Exon Structure for
MRPS9
ECgene alternative splicing isoforms for
MRPS9

Expression for MRPS9 Gene

mRNA expression in normal human tissues for MRPS9 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for MRPS9 Gene

SOURCE GeneReport for Unigene cluster for MRPS9 Gene Hs.590900

genes like me logo Genes that share expressions with MRPS9: view

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for MRPS9 Gene

Orthologs for MRPS9 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for MRPS9 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia MRPS9 35
  • 99.33 (n)
  • 99.49 (a)
MRPS9 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia MRPS9 35
  • 79.38 (n)
  • 76.57 (a)
MRPS9 36
  • 79 (a)
OneToOne
dog
(Canis familiaris)
Mammalia MRPS9 35
  • 86.67 (n)
  • 83.04 (a)
MRPS9 36
  • 83 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mrps9 35
  • 80.34 (n)
  • 78.46 (a)
Mrps9 16
Mrps9 36
  • 78 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia MRPS9 36
  • 75 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia MRPS9 36
  • 77 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Mrps9 35
  • 81.2 (n)
  • 79.23 (a)
chicken
(Gallus gallus)
Aves MRPS9 35
  • 71.09 (n)
  • 68.56 (a)
MRPS9 36
  • 67 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia MRPS9 36
  • 62 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia mrps9 35
  • 68.4 (n)
  • 65.36 (a)
zebrafish
(Danio rerio)
Actinopterygii mrps9 35
  • 59.49 (n)
  • 58.27 (a)
mrps9 36
  • 57 (a)
OneToOne
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP010268 35
  • 51.3 (n)
  • 43.48 (a)
fruit fly
(Drosophila melanogaster)
Insecta mRpS9 35
  • 52.27 (n)
  • 46.83 (a)
mRpS9 36
  • 42 (a)
OneToOne
mRpS9 37
  • 40 (a)
worm
(Caenorhabditis elegans)
Secernentea mrps-9 35
  • 44.9 (n)
  • 36.56 (a)
mrps-9 36
  • 31 (a)
OneToOne
F09G8.3 37
  • 33 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes MRPS9 36
  • 28 (a)
OneToOne
MRPS9 38
Species with no ortholog for MRPS9:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for MRPS9 Gene

ENSEMBL:
Gene Tree for MRPS9 (if available)
TreeFam:
Gene Tree for MRPS9 (if available)

Paralogs for MRPS9 Gene

No data available for Paralogs for MRPS9 Gene

Variants for MRPS9 Gene

Sequence variations from dbSNP and Humsavar for MRPS9 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type MAF
rs934235 -- 105,044,555(+) GAAAA(A/G)TAGCA intron-variant
rs2217420 -- 105,065,354(+) ATTTA(C/T)TTCAG intron-variant
rs3739156 -- 105,049,579(-) GTGTA(C/T)GAGCA intron-variant
rs3739157 -- 105,049,537(-) ACTCA(C/T)CATAC intron-variant
rs3739158 -- 105,049,534(-) CACCA(A/T)ACTAA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for MRPS9 Gene

Variant ID Type Subtype PubMed ID
nsv820123 CNV Gain 19587683
dgv85e180 CNV Loss 20482838
dgv86e180 CNV Deletion 20482838
esv27425 CNV Loss 19812545
esv2663750 CNV Deletion 23128226
esv2720474 CNV Deletion 23290073
esv2720475 CNV Deletion 23290073
esv2720476 CNV Deletion 23290073
esv2720477 CNV Deletion 23290073
esv2720478 CNV Deletion 23290073
esv2720479 CNV Deletion 23290073

Relevant External Links for MRPS9 Gene

HapMap Linkage Disequilibrium report
MRPS9

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MRPS9 Gene

Disorders for MRPS9 Gene

Relevant External Links for MRPS9

Genetic Association Database (GAD)
MRPS9
Human Genome Epidemiology (HuGE) Navigator
MRPS9
genes like me logo Genes that share disorders with MRPS9: view

No data available for UniProtKB/Swiss-Prot for MRPS9 Gene

Publications for MRPS9 Gene

  1. The small subunit of the mammalian mitochondrial ribosome: identification of the full complement of ribosomal proteins present. (PMID: 11279123) Koc E.C. … Spremulli L.L. (J. Biol. Chem. 2001) 2 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PMID: 20877624) Hendrickson S.L. … O'Brien S.J. (PLoS ONE 2010) 3 48
  4. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PMID: 21139048) Danielsen J.M. … Nielsen M.L. (Mol. Cell Proteomics 2011) 3
  5. Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics. (PMID: 21145461) Bennett E.J. … Harper J.W. (Cell 2010) 3

Products for MRPS9 Gene

Sources for MRPS9 Gene

Back to Top

Content