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MRPS7 Gene

protein-coding   GIFtS: 59
GCID: GC17P073254

Mitochondrial Ribosomal Protein S7

Microbiology & Infectious Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Mitochondrial Ribosomal Protein S71 2     28S Ribosomal Protein S7, Mitochondrial2
MRP-S72 3     30S Ribosomal Protein S7 Homolog2
S7mt2 3     MRP-S2
bMRP-27a2 3     RP-S72
bMRP27a2 3     RPMS72

External Ids:    HGNC: 144991   Entrez Gene: 510812   Ensembl: ENSG000001254457   OMIM: 6119745   UniProtKB: Q9Y2R93   

Export aliases for MRPS7 gene to outside databases

Previous GC identifers: GC17P076316 GC17P073721 GC17P073854 GC17P070769 GC17P068667


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for MRPS7 Gene:
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the
mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit.
They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is
reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain
a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and
sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a
28S subunit protein. In the prokaryotic ribosome, the comparable protein is thought to play an essential role in
organizing the 3' domain of the 16 S rRNA in the vicinity of the P- and A-sites. Pseudogenes corresponding to
this gene are found on chromosomes 8p and 12p. (provided by RefSeq, Jul 2008)

GeneCards Summary for MRPS7 Gene:
MRPS7 (mitochondrial ribosomal protein S7) is a protein-coding gene. Diseases associated with MRPS7 include campylobacteriosis, and dubin-johnson syndrome. GO annotations related to this gene include structural constituent of ribosome and RNA binding.

Gene Wiki entry for MRPS7 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000017.11  NT_010783.16  NC_018928.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the MRPS7 gene promoter:
         Pax-2   Lmo2   Pax-2a   AP-4   E47   c-Ets-1   GCNF-1   STAT3   c-Myb   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMRPS7 promoter sequence
   Search Chromatin IP Primers for MRPS7

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MRPS7


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q25   Ensembl cytogenetic band:  17q25.1   HGNC cytogenetic band: 17q25.1

MRPS7 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MRPS7 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17P073254:  view genomic region     (about GC identifiers)

Start:
73,257,749 bp from pter      End:
73,262,457 bp from pter
Size:
4,709 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: RT07_HUMAN, Q9Y2R9 (See protein sequence)
Recommended Name: 28S ribosomal protein S7, mitochondrial precursor  
Size: 242 amino acids; 28134 Da
Subunit: Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30
distinct proteins (By similarity)
Secondary accessions: B2R9N5 Q53GD6

Explore the universe of human proteins at neXtProt for MRPS7: NX_Q9Y2R9

Explore proteomics data for MRPS7 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys48, Lys125, Lys163, Lys221
  • Modification sites at PhosphoSitePlus

  • See MRPS7 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_057055.2  
    ENSEMBL proteins: 
     ENSP00000463263   ENSP00000245539   ENSP00000463683   ENSP00000462677   ENSP00000463870  
     ENSP00000462506  

    MRPS7 Human Recombinant Protein Products:

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    Novus Biologicals MRPS7 Protein
    Novus Biologicals MRPS7 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for MRPS7

    MRPS7 Antibody Products:

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    Abcam antibodies for MRPS7
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    Search ThermoFisher Antibodies for MRPS7
    LSBio Antibodies in human, mouse, rat for MRPS7

    MRPS7 Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    GenScript Custom Assay Services for MRPS7
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for MRPS7
    Cloud-Clone Corp. CLIAs for MRPS7


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    MRPS: Mitochondrial ribosomal proteins / small subunits

    2 InterPro protein domains:
     IPR023798 Ribosomal_S7_dom
     IPR000235 Ribosomal_S5/S7

    Graphical View of Domain Structure for InterPro Entry Q9Y2R9

    ProtoNet protein and cluster: Q9Y2R9

    1 Blocks protein domain: IPB000235 Ribosomal protein S7

    UniProtKB/Swiss-Prot: RT07_HUMAN, Q9Y2R9
    Similarity: Belongs to the ribosomal protein S7P family


    MRPS7 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003723RNA binding ISS--
    GO:0003735structural constituent of ribosome ISS--
    GO:0044822poly(A) RNA binding IDA--
         
    MRPS7 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for MRPS7:
     Increased G1 DNA content  Increased HPV18 LCR reporter a 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for MRPS7
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for MRPS7
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for MRPS7

    miRNA
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    Block miRNA regulation of human, mouse, rat MRPS7 using miScript Target Protectors
    2 qRT-PCR Assays for microRNAs that regulate MRPS7:
    hsa-miR-576-5p hsa-miR-4263
    SwitchGear 3'UTR luciferase reporter plasmidMRPS7 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for MRPS7
    Predesigned siRNA for gene silencing in human, mouse, rat MRPS7

    Gene Editing
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    DNA2.0 Custom Protein Engineering Service for MRPS7

    Clone
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: MRPS7 (NM_015971)
    Sino Biological Human cDNA Clone for MRPS7
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MRPS7
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MRPS7

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for MRPS7 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MRPS7


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    RT07_HUMAN, Q9Y2R9: Mitochondrion (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol4
    mitochondrion4
    nucleus2
    plasma membrane2
    extracellular1
    vacuole1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion IEA--
    GO:0022627cytosolic small ribosomal subunit ISS--

    MRPS7 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for MRPS7 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1CFTR translational fidelity class I mutations
    Ribosome0.54

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways




    1 Kegg Pathway  (Kegg details for MRPS7):
        Ribosome


    MRPS7 for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for MRPS7
    Interactions:

        GeneGlobe Interaction Network for MRPS7

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for MRPS7 (Q9Y2R92, 3 ENSP000002455394) via UniProtKB, MINT, STRING, and/or I2D (see all 498)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ICT1Q141972, 3, ENSP000003015854MINT-8079030 I2D: score=1 STRING: ENSP00000301585
    UBCP0CG483, ENSP000003448184I2D: score=1 STRING: ENSP00000344818
    MRPS9P829332, ENSP000002584554MINT-8079030 STRING: ENSP00000258455
    MRPS10P826642, ENSP000000534684MINT-8079030 STRING: ENSP00000053468
    MRPS2Q9Y3992, ENSP000002416004MINT-8079030 STRING: ENSP00000241600
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006412translation ISS--

    MRPS7 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for MRPS7 (RT07)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for MRPS7 gene: 
    NM_015971.3  

    Unigene Cluster for MRPS7:

    Mitochondrial ribosomal protein S7
    Hs.71787  [show with all ESTs]
    Unigene Representative Sequence: NM_015971
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000579761 ENST00000245539(uc002jnm.4) ENST00000579002 ENST00000583407
    ENST00000577767 ENST00000581993 ENST00000584678
    Congresses - knowledge worth sharing:
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat MRPS7 using miScript Target Protectors
    2 qRT-PCR Assays for microRNAs that regulate MRPS7:
    hsa-miR-576-5p hsa-miR-4263
    SwitchGear 3'UTR luciferase reporter plasmidMRPS7 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for MRPS7
    Predesigned siRNA for gene silencing in human, mouse, rat MRPS7
    Clone
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    OriGene clones in human, mouse for MRPS7 (see all 6)
    OriGene ORF clones in mouse, rat for MRPS7
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: MRPS7 (NM_015971)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MRPS7
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MRPS7
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for MRPS7
    OriGene qSTAR qPCR primer pairs in human, mouse for MRPS7
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat MRPS7
      QuantiTect SYBR Green Assays in human, mouse, rat MRPS7
      QuantiFast Probe-based Assays in human, mouse, rat MRPS7

    Additional mRNA sequence: 

    AF077042.1 AK222995.1 AK313854.1 BC000241.1 BC050641.2 

    13 DOTS entries:

    DT.456328  DT.100796358  DT.121005112  DT.100796364  DT.121005108  DT.121005222  DT.100021262  DT.91766614 
    DT.100796365  DT.121005172  DT.95173884  DT.100699845  DT.99975963 

    Selected AceView cDNA sequences (see all 319):

    BM837240 BF688551 CR620281 BX397403 CR608852 Z46044 BM784754 BG475112 
    BM470192 CR626657 CR618302 CR600124 BE615425 BE267532 BU190702 C02351 
    AW245610 BE531313 BQ930311 BC050641 BQ428149 BM826649 BM457809 BU608752 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    MRPS7 expression in normal human tissues (normalized intensities)      MRPS7 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGGTGCAGCA
    MRPS7 Expression
    About this image


    MRPS7 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 6) fully expand
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Cerebral Cortex
     
     Trophoblast (Extraembryonic Tissues)
             Trophoblast Cells Trophoblast
     
     Ovary (Reproductive System)
             Oviduct
     
     Testis (Reproductive System)
             Leydig Cells Testis Interstitium
     
     Liver (Hepatobiliary System)
             Hepatocytes Liver Lobule
    MRPS7 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    MRPS7 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.71787
        Custom PCR Arrays for MRPS7
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for MRPS7
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MRPS7

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for MRPS7 gene from Selected species (see all 19)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Mrps71 , 5 mitchondrial ribosomal protein S71, 5 82.78(n)1
    84.71(a)1
      11 (80.90 cM)5
    505291  NM_025305.21  NP_079581.11 
     1156039255 
    chicken
    (Gallus gallus)
    Aves MRPS71 mitochondrial ribosomal protein S7 68.24(n)
    66.95(a)
      422122  NM_001031109.2  NP_001026280.2 
    lizard
    (Anolis carolinensis)
    Reptilia MRPS76
    mitochondrial ribosomal protein S7
    68(a)
    1 ↔ 1
    2(114656620-114662887)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.71752 Xenopus laevis transcribed sequence with weak similarity more 73.21(n)    BJ617680.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufb66e052 wufb66e05 73.27(n)   322589  CK353141.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta mRpS71 , 3 protein biosynthesis structural
    constituent of more3
    mitochondrial ribosomal protein S71
    41(a)3
    54.42(n)1
    46.99(a)1
      31D113
    344121  NM_001273410.11  NP_001260339.11 
    worm
    (Caenorhabditis elegans)
    Secernentea mrps-71 mrps-7 47.92(n)
    37.02(a)
      190379  NM_070381.2  NP_502782.2 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons rps71 rps7 42.89(n)
    30.77(a)
      4386140  rps7_3_7525094  NP_051118.1 
    rice
    (Oryza sativa)
    Liliopsida rps71 rps7 41.96(n)
    36.36(a)
      3131444  rps7_2_11466861  NP_039458.1 


    ENSEMBL Gene Tree for MRPS7 (if available)
    TreeFam Gene Tree for MRPS7 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for MRPS7 gene

    MRPS7 for paralogs           About GeneDecksing


    2 Pseudogenes.org Pseudogenes for MRPS7
    PGOHUM00000262877 PGOHUM00000263191


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for MRPS7 (see all 39)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1829923861,2
    --73260451(+) TATTCA/GTATCC 1 -- int10--------
    rs1167603701,2
    C,F--73260464(+) TCTTTG/ATATGC 1 -- int11Minor allele frequency- A:0.04WA 118
    rs1460452151,2
    C--73260514(+) ATCAGC/TGTTTG 1 -- int10--------
    rs345812521,2
    C--73260755(+) TTAAC-/TTTTTT 1 -- int10--------
    rs1143242381,2
    F--73260810(+) GTGCAG/ATGCTG 1 -- int11Minor allele frequency- A:0.05WA 118
    rs80675171,2
    C,A,H--73260814(+) agtgcC/Tgtaat 1 -- int114Minor allele frequency- T:0.02NA WA CSA EA 377
    rs1863234361,2
    --73260817(+) GCTGTA/TATCTC 1 -- int10--------
    rs1902981351,2
    --73260854(+) CTCCCA/GGGTTC 1 -- int10--------
    rs1388695321,2
    --73260918(+) TGGCCA/GCCACC 1 -- int10--------
    rs1504242971,2
    C--73260930(+) TGCCC-/AAGCTA 1 -- int10--------

    HapMap Linkage Disequilibrium report for MRPS7 (73257749 - 73262457 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for MRPS7:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv908760CNV Loss21882294
    nsv908761CNV Loss21882294
    nsv908758CNV Loss21882294
    nsv510727CNV Loss20534489

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing MRPS7
    DNA2.0 Custom Variant and Variant Library Synthesis for MRPS7

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 611974    OMIM disorders: --

    11 diseases for MRPS7:    About MalaCards
    campylobacteriosis    dubin-johnson syndrome    pseudoxanthoma elasticum    tonsillitis
    pneumonia    tuberculosis    malaria    cerebritis
    thyroiditis    endotheliitis    prostatitis

    3 diseases from the University of Copenhagen DISEASES database for MRPS7:
    Campylobacteriosis     Dubin-Johnson syndrome     Pseudoxanthoma elasticum

    MRPS7 for disorders           About GeneDecksing

    Genetic Association Database (GAD): MRPS7
    Human Genome Epidemiology (HuGE) Navigator: MRPS7 (1 document)

    Export disorders for MRPS7 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for MRPS7 gene, integrated from 10 sources (see all 39):
    (articles sorted by number of sources associating them with MRPS7)
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    1. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (PLoS ONE 2010)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. The small subunit of the mammalian mitochondrial ribosome: identification of the full complement of ribosomal proteins present. (PubMed id 11279123)1, 2 Koc E.C.... Spremulli L.L. (J. Biol. Chem. 2001)
    4. Proteomic analysis of the mammalian mitochondrial ribosome. Identification of protein components in the 28S small subunit. (PubMed id 11402041)1, 2 Suzuki T....Watanabe K. (J. Biol. Chem. 2001)
    5. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)1, 2 Zhang Q.-H.... Chen Z. (Genome Res. 2000)
    6. Identification of a mammalian mitochondrial homolog of ribosomal protein S7. (PubMed id 10581179)1, 2 Koc E.C.... Spremulli L.L. (Biochem. Biophys. Res. Commun. 1999)
    7. Identification and characterization of over 100 mitochondrial ribosomal protein pseudogenes in the human genome. (PubMed id 12706105)1, 9 Zhang Z. and Gerstein M. (Genomics 2003)
    8. The human mitochondrial ribosomal protein genes: mapping of 54 genes to the chromosomes and implications for human disorders. (PubMed id 11543634)1, 9 Kenmochi N.... Tanaka T. (Genomics 2001)
    9. Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS. (PubMed id 23455922)1 Varjosalo M....Superti-Furga G. (Nat. Methods 2013)
    10. Profiling of Parkin-binding partners using tandem affinity purification. (PubMed id 24244333)1 Zanon A....Pichler I. (PLoS ONE 2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 51081 HGNC: 14499 AceView: MRPS7 Ensembl:ENSG00000125445 euGenes: HUgn51081
    ECgene: MRPS7 Kegg: 51081 H-InvDB: MRPS7

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for MRPS7 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for MRPS7 gene:
    Search GeneIP for patents involving MRPS7

    GeneCards and IP:
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