Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

MRPS7 Gene

protein-coding   GIFtS: 59
GCID: GC17P073254

Mitochondrial Ribosomal Protein S7

Microbiology & Infectious Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Mitochondrial Ribosomal Protein S71 2     28S Ribosomal Protein S7, Mitochondrial2
MRP-S72 3     30S Ribosomal Protein S7 Homolog2
S7mt2 3     MRP-S2
bMRP-27a2 3     RP-S72
bMRP27a2 3     RPMS72

External Ids:    HGNC: 144991   Entrez Gene: 510812   Ensembl: ENSG000001254457   OMIM: 6119745   UniProtKB: Q9Y2R93   

Export aliases for MRPS7 gene to outside databases

Previous GC identifers: GC17P076316 GC17P073721 GC17P073854 GC17P070769 GC17P068667


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for MRPS7 Gene:
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the
mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit.
They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is
reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain
a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and
sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a
28S subunit protein. In the prokaryotic ribosome, the comparable protein is thought to play an essential role in
organizing the 3' domain of the 16 S rRNA in the vicinity of the P- and A-sites. Pseudogenes corresponding to
this gene are found on chromosomes 8p and 12p. (provided by RefSeq, Jul 2008)

GeneCards Summary for MRPS7 Gene: 
MRPS7 (mitochondrial ribosomal protein S7) is a protein-coding gene. Diseases associated with MRPS7 include campylobacteriosis, and dubin-johnson syndrome, and among its related super-pathways are Viral mRNA Translation. GO annotations related to this gene include structural constituent of ribosome and RNA binding.

Gene Wiki entry for MRPS7 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000017.10  NT_010783.15  NC_018928.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the MRPS7 gene promoter:
         Pax-2   Lmo2   Pax-2a   AP-4   E47   c-Ets-1   GCNF-1   STAT3   c-Myb   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMRPS7 promoter sequence
   Search SABiosciences Chromatin IP Primers for MRPS7

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MRPS7


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q25   Ensembl cytogenetic band:  17q25.1   HGNC cytogenetic band: 17q25.1

MRPS7 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MRPS7 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17P073254:  view genomic region     (about GC identifiers)

Start:
73,257,749 bp from pter      End:
73,262,457 bp from pter
Size:
4,709 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: RT07_HUMAN, Q9Y2R9 (See protein sequence)
Recommended Name: 28S ribosomal protein S7, mitochondrial precursor  
Size: 242 amino acids; 28134 Da
Subunit: Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30
distinct proteins (By similarity)
Subcellular location: Mitochondrion (By similarity)
Secondary accessions: B2R9N5 Q53GD6

Explore the universe of human proteins at neXtProt for MRPS7: NX_Q9Y2R9

Explore proteomics data for MRPS7 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9Y2R9

  • MRPS7 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    MRPS7 Protein Expression
    REFSEQ proteins: NP_057055.2  
    ENSEMBL proteins: 
     ENSP00000463263   ENSP00000245539   ENSP00000463683   ENSP00000462677   ENSP00000463870  
     ENSP00000462506  

    Human Recombinant Protein Products for MRPS7: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for MRPS7
    OriGene Protein Over-expression Lysate for MRPS7
    OriGene MassSpec for MRPS7 
    OriGene Custom Protein Services for MRPS7
    GenScript Custom Purified and Recombinant Proteins Services for MRPS7
    Novus Biologicals MRPS7 Protein
    Novus Biologicals MRPS7 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for MRPS7 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion IDA--
    GO:0005840ribosome ----
    GO:0022627cytosolic small ribosomal subunit ISS--

    MRPS7 for ontologies           About GeneDecksing



    MRPS7 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for MRPS7
    GenScript Custom Superior Antibodies Services for MRPS7
    Novus Biologicals MRPS7 Antibodies
    Abcam antibodies for MRPS7
    Cloud-Clone Corp. Antibodies for MRPS7 
    Search ThermoFisher Antibodies for MRPS7
    LSBio Antibodies in human, mouse, rat for MRPS7 

    Assay Products for MRPS7: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for MRPS7
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for MRPS7
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for MRPS7 
    Cloud-Clone Corp. CLIAs for MRPS7


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    MRPS: Mitochondrial ribosomal proteins / small subunits

    2 InterPro protein domains:
     IPR023798 Ribosomal_S7_dom
     IPR000235 Ribosomal_S5/S7

    Graphical View of Domain Structure for InterPro Entry Q9Y2R9

    ProtoNet protein and cluster: Q9Y2R9

    1 Blocks protein domain: IPB000235 Ribosomal protein S7

    UniProtKB/Swiss-Prot: RT07_HUMAN, Q9Y2R9
    Similarity: Belongs to the ribosomal protein S7P family


    MRPS7 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003723RNA binding ISS--
    GO:0003735structural constituent of ribosome ISS--
         
    MRPS7 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for MRPS7:
     Increased G1 DNA content  Increased HPV18 LCR reporter a 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for MRPS7 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for MRPS7

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for MRPS7 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for MRPS7 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MRPS7
    2 QIAGEN miScript miRNA Assays for microRNAs that regulate MRPS7:
    hsa-miR-576-5p hsa-miR-4263
    SwitchGear 3'UTR luciferase reporter plasmidMRPS7 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for MRPS7
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MRPS7

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for MRPS7
    Sirion Biotech Customized adenovirus for overexpression of MRPS7

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for MRPS7 (see all 7)
    OriGene ORF clones in mouse, rat for MRPS7
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: MRPS7 (NM_015971)
    Sino Biological Human cDNA Clone for MRPS7
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MRPS7
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MRPS7
    Sirion Biotech Customized lentivirus for stable overexpression of MRPS7 
                         Customized lentivirus expression plasmids for stable overexpression of MRPS7 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for MRPS7
    Search LifeMap BioReagents cell lines for MRPS7
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MRPS7


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for MRPS7 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Viral mRNA Translation
    Ribosome0.59

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways




    1         Kegg Pathway  (Kegg details for MRPS7):
        Ribosome


    MRPS7 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for MRPS7

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/279 Interacting proteins for MRPS7 (Q9Y2R92, 3 ENSP000002455394) via UniProtKB, MINT, STRING, and/or I2D (see all 279)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ICT1Q141972, 3, ENSP000003015854MINT-8079030 I2D: score=1 STRING: ENSP00000301585
    ASF1BQ9NVP23, ENSP000002633824I2D: score=2 STRING: ENSP00000263382
    MRPS11P829122, ENSP000003173764MINT-8079030 STRING: ENSP00000317376
    UBCP0CG483, ENSP000003448184I2D: score=1 STRING: ENSP00000344818
    MRPS14O607832, ENSP000004207144MINT-8079030 STRING: ENSP00000420714
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006412translation ISS--

    MRPS7 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for MRPS7 (RT07)

    Search CenterWatch for drugs/clinical trials and news about MRPS7 / RT07

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for MRPS7 gene: 
    NM_015971.3  

    Unigene Cluster for MRPS7:

    Mitochondrial ribosomal protein S7
    Hs.71787  [show with all ESTs]
    Unigene Representative Sequence: NM_015971
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000579761 ENST00000245539(uc002jnm.4) ENST00000579002 ENST00000583407
    ENST00000577767 ENST00000581993 ENST00000584678
    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MRPS7
    2 QIAGEN miScript miRNA Assays for microRNAs that regulate MRPS7:
    hsa-miR-576-5p hsa-miR-4263
    SwitchGear 3'UTR luciferase reporter plasmidMRPS7 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for MRPS7
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MRPS7
    Clone
    Products:
         
    OriGene clones in human, mouse for MRPS7 (see all 7)
    OriGene ORF clones in mouse, rat for MRPS7
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: MRPS7 (NM_015971)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MRPS7
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MRPS7
    Sirion Biotech Customized lentivirus for stable overexpression of MRPS7 
                         Customized lentivirus expression plasmids for stable overexpression of MRPS7 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for MRPS7
    OriGene qSTAR qPCR primer pairs in human, mouse for MRPS7
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat MRPS7
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MRPS7
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MRPS7

    Additional mRNA sequence: 

    AF077042.1 AK222995.1 AK313854.1 BC000241.1 BC050641.2 

    13 DOTS entries:

    DT.456328  DT.100796358  DT.121005112  DT.100796364  DT.121005108  DT.121005222  DT.100021262  DT.91766614 
    DT.100796365  DT.121005172  DT.95173884  DT.100699845  DT.99975963 

    24/319 AceView cDNA sequences (see all 319):

    BE615855 BM694866 CR614985 BM459815 BM457809 BM826649 Z46044 BF688551 
    BU190702 BQ428149 BQ955096 CR608852 BQ695164 BQ310641 BQ949789 BU608752 
    CR600124 CR599341 BM699336 BE743647 BE614899 BE278110 CR620281 CR609316 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    MRPS7 expression in normal human tissues (normalized intensities)      MRPS7 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGGTGCAGCA
    MRPS7 Expression
    About this image


    MRPS7 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/31 selected tissues (see all 31) fully expand
     
     Testis (Reproductive System)    fully expand to see all 4 entries
             Leydig Cells Testis Interstitium
             seminal vesicle ; glandular cells   
     
     Colon (Gastrointestinal Tract)    fully expand to see all 4 entries
             colon ; peripheral nerve/ganglion   
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Cerebral Cortex
     
     Epithelium
             oral mucosa ; squamous epithelial cells   
     
     Tonsil (Hematopoietic System)    fully expand to see all 3 entries
             tonsil ; squamous epithelial cells   

    See MRPS7 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for MRPS7

    SOURCE GeneReport for Unigene cluster: Hs.71787
        SABiosciences Custom PCR Arrays for MRPS7
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for MRPS7
    OriGene qSTAR qPCR primer pairs in human, mouse for MRPS7
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat MRPS7
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MRPS7
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MRPS7
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MRPS7

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for MRPS7 gene from 7/17 species (see all 17)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Mrps71 , 5 mitchondrial ribosomal protein S71, 5 82.78(n)1
    84.71(a)1
      11 (80.90 cM)5
    505291  NM_025305.21  NP_079581.11 
     1156039255 
    chicken
    (Gallus gallus)
    Aves MRPS71 mitochondrial ribosomal protein S7 66.06(n)
    67.27(a)
      422122  NM_001031109.1  NP_001026280.1 
    lizard
    (Anolis carolinensis)
    Reptilia MRPS76
    Uncharacterized protein
    64(a)
    1 ↔ 1
    2(114656620-114662887)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.71752 Xenopus laevis transcribed sequence with weak similarity more 73.21(n)    BJ617680.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufb66e052 wufb66e05 73.27(n)   322589  CK353141.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta mRpS71 , 3 protein biosynthesis structural
    constituent of more3
    mitochondrial ribosomal protein S71
    41(a)3
    51.58(n)1
    42.63(a)1
      31D113
    344121  NM_078813.21  NP_523537.11 
    worm
    (Caenorhabditis elegans)
    Secernentea mrps-71 Protein MRPS-7 47.92(n)
    37.02(a)
      190379  NM_070381.2  NP_502782.2 


    ENSEMBL Gene Tree for MRPS7 (if available)
    TreeFam Gene Tree for MRPS7 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for MRPS7 gene

    MRPS7 for paralogs           About GeneDecksing


    2 Pseudogenes.org Pseudogenes for MRPS7
    PGOHUM00000262877 PGOHUM00000263191


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/39 SNPs in MRPS7 are shown (see all 39)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0300764
    ----see VAR_0300762 A V mis40--------
    rs1829923861,2
    --73260451(+) TATTCA/GTATCC 1 -- int10--------
    rs1167603701,2
    C,F--73260464(+) TCTTTG/ATATGC 1 -- int11Minor allele frequency- A:0.04WA 118
    rs1460452151,2
    C--73260514(+) ATCAGC/TGTTTG 1 -- int10--------
    rs345812521,2
    C--73260755(+) TTAAC-/TTTTTT 1 -- int10--------
    rs1143242381,2
    F--73260810(+) GTGCAG/ATGCTG 1 -- int11Minor allele frequency- A:0.05WA 118
    rs80675171,2
    C,A,H--73260814(+) agtgcC/Tgtaat 1 -- int114Minor allele frequency- T:0.02NA WA CSA EA 377
    rs1863234361,2
    --73260817(+) GCTGTA/TATCTC 1 -- int10--------
    rs1902981351,2
    --73260854(+) CTCCCA/GGGTTC 1 -- int10--------
    rs1388695321,2
    --73260918(+) TGGCCA/GCCACC 1 -- int10--------

    HapMap Linkage Disequilibrium report for MRPS7 (73257749 - 73262457 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for MRPS7:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv908760CNV Loss21882294
    nsv908761CNV Loss21882294
    nsv908758CNV Loss21882294
    nsv510727CNV Loss20534489

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing MRPS7
    DNA2.0 Custom Variant and Variant Library Synthesis for MRPS7

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 611974    OMIM disorders: --

    4 diseases for MRPS7:    About MalaCards
    campylobacteriosis    dubin-johnson syndrome    pneumonia    tuberculosis

    3 diseases from the University of Copenhagen DISEASES database for MRPS7:
    Campylobacteriosis     Dubin-Johnson syndrome     Pseudoxanthoma elasticum

    MRPS7 for disorders           About GeneDecksing

    Genetic Association Database (GAD): MRPS7
    Human Genome Epidemiology (HuGE) Navigator: MRPS7 (1 document)

    Export disorders for MRPS7 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for MRPS7 gene, integrated from 9 sources (see all 38):
    (articles sorted by number of sources associating them with MRPS7)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Genetic variants in nuclear-encoded mitochondrial gen es influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (2010)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. The small subunit of the mammalian mitochondrial ribosome: identification of the full complement of ribosomal proteins present. (PubMed id 11279123)1, 2 Koc E.C.... Spremulli L.L. (2001)
    4. Proteomic analysis of the mammalian mitochondrial ribosome. Identification of protein components in the 28S small subunit. (PubMed id 11402041)1, 2 Suzuki T....Watanabe K. (2001)
    5. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)1, 2 Zhang Q.-H.... Chen Z. (2000)
    6. Identification of a mammalian mitochondrial homolog of ribosomal protein S7. (PubMed id 10581179)1, 2 Koc E.C.... Spremulli L.L. (1999)
    7. Identification and characterization of over 100 mitochondrial ribosomal protein pseudogenes in the human genome. (PubMed id 12706105)1, 9 Zhang Z. and Gerstein M. (2003)
    8. The human mitochondrial ribosomal protein genes: mapping of 54 genes to the chromosomes and implications for human disorders. (PubMed id 11543634)1, 9 Kenmochi N....Tanaka T. (2001)
    9. Interlaboratory reproducibility of large-scale human p rotein-complex analysis by standardized AP-MS. (PubMed id 23455922)1 Varjosalo M....Superti-Furga G. (2013)
    10. p32/gC1qR is indispensable for fetal development and m itochondrial translation: importance of its RNA-binding ability. (PubMed id 22904065)1 Yagi M....Kang D. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 51081 HGNC: 14499 AceView: MRPS7 Ensembl:ENSG00000125445 euGenes: HUgn51081
    ECgene: MRPS7 Kegg: 51081 H-InvDB: MRPS7

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for MRPS7 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for MRPS7 gene:
    Search GeneIP for patents involving MRPS7

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for MRPS7  
     OriGene qPCR primer pairs and template standards for MRPS7   OriGene Protein Over-expression Lysate for MRPS7  
     OriGene MassSpec something-or-other for MRPS7   OriGene clones in human, mouse for MRPS7  
     OriGene qSTAR qPCR primer pairs in human, mouse for MRPS7   OriGene Purified Protein for MRPS7  
     OriGene ORF clones in mouse, rat for MRPS7   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for MRPS7   OriGene Custom Protein Services for MRPS7  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat MRPS7
     QIAGEN SeqTarget long-range PCR primers for resequencing MRPS7
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MRPS7
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MRPS7
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MRPS7
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MRPS7
     GenScript Custom Purified and Recombinant Proteins Services for MRPS7 GenScript cDNA clones with any tag delivered in your preferred vector for MRPS7
     GenScript Custom Assay Services for MRPS7 GenScript Custom Superior Antibodies Services for MRPS7
     GenScript Custom overexpressing Cell Line Services for MRPS7 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in MRPS7 promoter
     Search Chromatin IP Primers for MRPS7
     RT2 qPCR Primer Assay in human, mouse, rat MRPS7
     GNC Network for MRPS7
     SABiosciences Custom PCR Arrays for MRPS7
     Search Tocris compounds for MRPS7 (RT07)
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological Cell Lysates
     cDNA Clones for MRPS7
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     MRPS7 antibodies
     MRPS7 proteins
     MRPS7 lysates
     Antibodies for MRPS7
     See all of Abcam's Antibodies, Kits and Proteins for MRPS7
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Proteins for MRPS7
     Antibodies for MRPS7
     ELISAs for MRPS7
     CLIAs for MRPS7
     Search LifeMap BioReagents cell lines for MRPS7
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MRPS7
     SwitchGear 3'UTR luciferase reporter plasmids for MRPS7
     SwitchGear Promoter luciferase reporter plasmids for MRPS7
     Search ThermoFisher Antibodies for MRPS7
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MRPS7
     inGenious Targeting Laboratory - Custom generated mouse model solutions for MRPS7
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for MRPS7
    Customized:
     lentivirus for stable overexpression of MRPS7
     lentivirus expression plasmids for stable overexpression of MRPS7
     adenovirus for overexpression of MRPS7
     LSBio Antibodies in human, mouse, rat for MRPS7
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      MRPS7 gene at Home site.
    hostname: 356977-web1.xennexinc.com index build: 106 solr: 1.4