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Aliases for MRPS36 Gene

Aliases for MRPS36 Gene

  • Mitochondrial Ribosomal Protein S36 2 3
  • MRP-S36 3 4
  • S36mt 3 4
  • 28S Ribosomal Protein S36, Mitochondrial 3
  • DC47 3

External Ids for MRPS36 Gene

Previous GeneCards Identifiers for MRPS36 Gene

  • GC05P068665
  • GC05P070079
  • GC05P068485
  • GC05P068529
  • GC05P068549
  • GC05P068514
  • GC05P065470
  • GC05P068515

Summaries for MRPS36 Gene

Entrez Gene Summary for MRPS36 Gene

  • Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. The mitochondrial ribosome (mitoribosome) consists of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. Pseudogenes corresponding to this gene are found on chromosomes 3p, 4q, 8p, 11q, 12q, and 20p. [provided by RefSeq, Jul 2008]

GeneCards Summary for MRPS36 Gene

MRPS36 (Mitochondrial Ribosomal Protein S36) is a Protein Coding gene. GO annotations related to this gene include structural constituent of ribosome.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MRPS36 Gene

Genomics for MRPS36 Gene

Regulatory Elements for MRPS36 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for MRPS36 Gene

Start:
69,217,746 bp from pter
End:
69,230,158 bp from pter
Size:
12,413 bases
Orientation:
Plus strand

Genomic View for MRPS36 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MRPS36 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MRPS36 Gene

Proteins for MRPS36 Gene

  • Protein details for MRPS36 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P82909-RT36_HUMAN
    Recommended name:
    28S ribosomal protein S36, mitochondrial
    Protein Accession:
    P82909
    Secondary Accessions:
    • Q9H2H4

    Protein attributes for MRPS36 Gene

    Size:
    103 amino acids
    Molecular mass:
    11466 Da
    Quaternary structure:
    • Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30 distinct proteins

neXtProt entry for MRPS36 Gene

Proteomics data for MRPS36 Gene at MOPED

Post-translational modifications for MRPS36 Gene

  • Ubiquitination at Lys33, Lys60, and Lys78
  • Modification sites at PhosphoSitePlus

Other Protein References for MRPS36 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for MRPS36 Gene

Domains for MRPS36 Gene

Gene Families for MRPS36 Gene

HGNC:
  • MRPS :Mitochondrial ribosomal proteins / small subunits

Protein Domains for MRPS36 Gene

ProtoNet:

Suggested Antigen Peptide Sequences for MRPS36 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MRPS36: view

No data available for UniProtKB/Swiss-Prot for MRPS36 Gene

Function for MRPS36 Gene

Gene Ontology (GO) - Molecular Function for MRPS36 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003735 structural constituent of ribosome NAS 11279123
genes like me logo Genes that share ontologies with MRPS36: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MRPS36 Gene

Localization for MRPS36 Gene

Subcellular locations from UniProtKB/Swiss-Prot for MRPS36 Gene

Mitochondrion.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for MRPS36 Gene COMPARTMENTS Subcellular localization image for MRPS36 gene
Compartment Confidence
mitochondrion 5
nucleus 2
chloroplast 1
cytosol 1

Gene Ontology (GO) - Cellular Components for MRPS36 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005739 mitochondrion ISS --
GO:0005743 mitochondrial inner membrane TAS --
GO:0005763 mitochondrial small ribosomal subunit IDA 11279123
genes like me logo Genes that share ontologies with MRPS36: view

Pathways for MRPS36 Gene

SuperPathways for MRPS36 Gene

No Data Available

Interacting Proteins for MRPS36 Gene

STRING Interaction Network Preview (showing 4 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000256441%0d%0a9606.ENSP00000472998%0d%0a9606.ENSP00000344818%0d%0a9606.ENSP00000447547%0d%0a9606.ENSP00000421307%0d%0a
Selected Interacting proteins: ENSP00000256441 for MRPS36 Gene via STRING

Gene Ontology (GO) - Biological Process for MRPS36 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006412 translation NAS 11279123
GO:0006996 organelle organization TAS --
GO:0032543 mitochondrial translation TAS --
GO:0070124 mitochondrial translational initiation TAS --
GO:0070125 mitochondrial translational elongation TAS --
genes like me logo Genes that share ontologies with MRPS36: view

No data available for Pathways by source for MRPS36 Gene

Transcripts for MRPS36 Gene

mRNA/cDNA for MRPS36 Gene

Unigene Clusters for MRPS36 Gene

Mitochondrial ribosomal protein S36:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for MRPS36

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for MRPS36

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MRPS36 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4a · 4b
SP1: -
SP2:

Relevant External Links for MRPS36 Gene

GeneLoc Exon Structure for
MRPS36
ECgene alternative splicing isoforms for
MRPS36

Expression for MRPS36 Gene

mRNA expression in normal human tissues for MRPS36 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for MRPS36 Gene

SOURCE GeneReport for Unigene cluster for MRPS36 Gene Hs.631971

genes like me logo Genes that share expressions with MRPS36: view

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for MRPS36 Gene

Orthologs for MRPS36 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MRPS36 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia MRPS36 35
  • 100 (n)
  • 100 (a)
MRPS36 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia MRPS36 35
  • 90.94 (n)
  • 93.2 (a)
MRPS36 36
  • 93 (a)
OneToOne
dog
(Canis familiaris)
Mammalia MRPS36 35
  • 92.56 (n)
  • 95.15 (a)
MRPS36 36
  • 89 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Gm7258 36
  • 77 (a)
OneToMany
Mrps36 35
  • 85.62 (n)
  • 84.31 (a)
Mrps36 16
Mrps36 36
  • 83 (a)
OneToMany
Mrps36-ps1 36
  • 83 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia MRPS36 36
  • 74 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Mrps36 35
  • 83.82 (n)
  • 81.55 (a)
chicken
(Gallus gallus)
Aves MRPS36 35
  • 70.96 (n)
  • 60.4 (a)
MRPS36 36
  • 54 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia MRPS36 36
  • 72 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.16822 35
tropical clawed frog
(Silurana tropicalis)
Amphibia mrps36 35
  • 67 (n)
  • 68.69 (a)
zebrafish
(Danio rerio)
Actinopterygii MRPS36 36
  • 42 (a)
OneToOne
si:dkey-190g11.7 35
  • 57.43 (n)
  • 54.46 (a)
Species with no ortholog for MRPS36:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MRPS36 Gene

ENSEMBL:
Gene Tree for MRPS36 (if available)
TreeFam:
Gene Tree for MRPS36 (if available)

Paralogs for MRPS36 Gene

genes like me logo Genes that share paralogs with MRPS36: view

No data available for Paralogs for MRPS36 Gene

Variants for MRPS36 Gene

Sequence variations from dbSNP and Humsavar for MRPS36 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type MAF
rs350123 -- 69,216,708(-) TGACT(A/G)CAGAG upstream-variant-2KB
rs2242350 -- 69,217,772(-) GGAGT(A/C)CCGGG utr-variant-5-prime
rs2242351 -- 69,217,745(-) TTCCC(C/G)GGACG upstream-variant-2KB
rs2930944 -- 69,220,006(-) GCCAT(A/C)CTCCT intron-variant
rs2930945 -- 69,218,876(-) CTACC(C/T)ACTGA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for MRPS36 Gene

Variant ID Type Subtype PubMed ID
nsv509066 CNV Insertion 20534489

Relevant External Links for MRPS36 Gene

HapMap Linkage Disequilibrium report
MRPS36

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MRPS36 Gene

Disorders for MRPS36 Gene

Relevant External Links for MRPS36

Genetic Association Database (GAD)
MRPS36
Human Genome Epidemiology (HuGE) Navigator
MRPS36
genes like me logo Genes that share disorders with MRPS36: view

No data available for UniProtKB/Swiss-Prot for MRPS36 Gene

Publications for MRPS36 Gene

  1. The small subunit of the mammalian mitochondrial ribosome: identification of the full complement of ribosomal proteins present. (PMID: 11279123) Koc E.C. … Spremulli L.L. (J. Biol. Chem. 2001) 2 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PMID: 20877624) Hendrickson S.L. … O'Brien S.J. (PLoS ONE 2010) 3 48
  4. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PMID: 21139048) Danielsen J.M. … Nielsen M.L. (Mol. Cell Proteomics 2011) 3
  5. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PMID: 21890473) Wagner S.A. … Choudhary C. (Mol. Cell Proteomics 2011) 3

Products for MRPS36 Gene

  • antibodies-online proteins for MRPS36
  • antibodies-online antibodies for MRPS36
  • antibodies-online kits for MRPS36

Sources for MRPS36 Gene

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