MRPS36 Gene
protein-coding GIFtS: 39
GCID: GC05P068514
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mitochondrial ribosomal protein S36
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Aliases
for MRPS36 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Mitochondrial Ribosomal Protein S361 2 | | MRP-S361 2 3 | | S36mt2 3 | | DC471 | | 28S Ribosomal Protein S36, Mitochondrial2 |
Export aliases for MRPS36 gene to outside databasesPrevious GC identifers: GC05P068665 GC05P070079 GC05P068485 GC05P068529 GC05P068549 GC05P065470 |
Summaries
for MRPS36 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for MRPS36:
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within themitochondrion. The mitochondrial ribosome (mitoribosome) consists of a small 28S subunit and a large 39S subunit. Theyhave an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed.Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA.Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes inbiochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein.Pseudogenes corresponding to this gene are found on chromosomes 3p, 4q, 8p, 11q, 12q, and 20p. (provided by RefSeq,Jul 2008)
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Genomic Views
for MRPS36 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000005.9 NC_018916.1 NT_006713.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the MRPS36 gene promoter:
GR Elk-1 Sp1 AML1a ATF-2 CBF-A FOXC1 c-Jun GR-alpha CBF(2)
Other transcription factors
Search SABiosciences Chromatin IP Primers for MRPS36
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MRPS36 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 5q13.2 Ensembl cytogenetic band: 5q13.2 HGNC chromosome: 5MRPS36 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 5 GeneLoc Exon Structure GeneLoc location for GC05P068514: view genomic region
(about GC identifiers)
Start:
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68,513,573 bp from pter |
End:
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68,525,985 bp from pter |
Size:
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12,413 bases |
Orientation:
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plus strand |
1 alternative location:
| Chr5+,PATCHES 68,905,921-68,918,331 |
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Proteins
for MRPS36 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: RT36_HUMAN, P82909 (See
protein sequence)Recommended Name: 28S ribosomal protein S36, mitochondrial Size: 103 amino acids; 11466 Da
Subunit: Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30 distinctproteins
Subcellular location: Mitochondrion
Secondary accessions: Q9H2H4Explore the universe of human proteins at neXtProt for MRPS36: NX_P82909
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P82909
MRPS36 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_150597.1
ENSEMBL proteins: ENSP00000256441 ENSP00000423659
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
MRPS36 for ontologies About GeneDecksing
MRPS36 Antibody Products:
Assay Products for MRPS36: |
Protein
Domains /
Families
for MRPS36 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: P82909 |
Function
for MRPS36 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MRPS36 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MRPS36 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: MRPS36 (NM_033281) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MRPS36 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MRPS36 |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003735 | structural constituent of ribosome |
NAS | 11279123 |
MRPS36 for ontologies About GeneDecksing
|
Pathways & Interactions
for MRPS36 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MRPS36
STRING Interaction
Network Preview (showing 2 interactants - click image to see more details)
2 Interacting proteins for MRPS36 (ENSP000002564414) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table
MRPS36 for ontologies About GeneDecksing
|
Drugs & Compounds
for MRPS36 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for MRPS36
Search CenterWatch for drugs/clinical trials and news about MRPS36 / RT36
|
Transcripts
for MRPS36 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for MRPS36 gene: NM_033281.5 Unigene Cluster for MRPS36: Mitochondrial ribosomal protein S36 Hs.631971 [show with all ESTs]Unigene Representative Sequence: BM8075954 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000256441(uc003jvq.3) ENST00000507022 ENST00000512880 ENST00000503793
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MRPS36 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MRPS36 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: MRPS36 (NM_033281) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MRPS36 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MRPS36 |
Additional cDNA sequence: AF086034.1 BC015966.1 BC017900.1 8 DOTS entries: DT.413236 DT.95272616 DT.95142495 DT.95272621 DT.120928938 DT.95272620 DT.120847974 DT.91671888 24/118 AceView cDNA sequences (see all 118): AA281009 BG573870 BP339493 CR600283 AI271778 CB269394 CA441774 N89606 H88798 AA878659 AF086034 CR609840 AI826702 W16974 BM669835 BC017900 BQ100685 BF438566 BQ100962 AI873126 BQ771610 AL530902 BI962981 N68316
GeneLoc Exon Structure
2 Alternative Splicing Database (ASD) splice patterns (SP) for MRPS36 About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b |
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| SP1: | | | | | - | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for MRPS36
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Expression
for MRPS36 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| MRPS36 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See MRPS36 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for MRPS36
SOURCE GeneReport for Unigene cluster: Hs.631971
SABiosciences Custom PCR Arrays for MRPS36
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MRPS36
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat MRPS36 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MRPS36 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MRPS36 |
Orthologs
for MRPS36 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for MRPS36 gene from 5/10 species (see all 10) About this table
ENSEMBL Gene Tree for MRPS36 (if available)
TreeFam Gene Tree for MRPS36 (if available) |
Paralogs
for MRPS36 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for MRPS36 gene
MRPS36 for paralogs About GeneDecksing
5/6 Pseudogenes.org Pseudogenes for MRPS36 (see all 6)
PGOHUM00000242893 PGOHUM00000239425 PGOHUM00000247447 PGOHUM00000237526 PGOHUM00000246158
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Genomic Variants
for MRPS36 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 5 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for MRPS36 (68513573 - 68525985 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for MRPS36: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MRPS36 |
|
Disorders
/ Diseases
for MRPS36 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
 MRPS36 for disorders About MalaCards
MRPS36 for disorders About GeneDecksing
OMIM gene information: 611996
OMIM disorders: --
Human Genome Epidemiology (HuGE) Navigator: MRPS36 (1 document)
Export disorders for MRPS36 gene to outside databases
|
Publications
for MRPS36 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for MRPS36 gene, integrated from 9 sources (see all 15):
(articles sorted by number of sources associating them with MRPS36) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The small subunit of the mammalian mitochondrial ribosome: identification of the full complement of ribosomal proteins present. (PubMed id 11279123)1, 2, 3 Koc E.C.... Spremulli L.L. (2001)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
- Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (2010)
- Genetic variants in nuclear-encoded mitochondrial gen es influence AIDS progression. (PubMed id 20877624)1 Hendrickson S.L....O'Brien S.J. (2010)
- A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (2008)
- Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
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External Searches for MRPS36 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing MRPS36 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing MRPS36 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing MRPS36 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for MRPS36 | Pharmacogenomics, SNPs, Pathways |
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| | |
About This Section
| Patent Information for MRPS36 gene:
Search GeneIP for patents involving MRPS36
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for MRPS36 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for MRPS36 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MRPS36 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MRPS36 | | | OriGene Protein Over-expression Lysate for MRPS36 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for MRPS36 | | OriGene 3'-UTR Clone for MRPS36 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MRPS36 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MRPS36 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for MRPS36 | | OriGene Custom Protein Services for MRPS36 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat MRPS36 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MRPS36 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MRPS36 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MRPS36 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MRPS36 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MRPS36 |
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 | | | MRPS36 Proteins, Antibodies, CLIAs, and ELISAs |
| | | |  |  |  | | | | Search ThermoFisher Antibodies for MRPS36 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MRPS36 |
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