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Aliases for MRPS24 Gene

Aliases for MRPS24 Gene

  • Mitochondrial Ribosomal Protein S24 2 3
  • MRP-S24 3 4
  • BMRP-47 3 4
  • BMRP47 3 4
  • S24mt 3 4
  • 28S Ribosomal Protein S24, Mitochondrial 3
  • Mitochondrial 28S Ribosomal Protein S24 3
  • HSPC335 3

External Ids for MRPS24 Gene

Summaries for MRPS24 Gene

Entrez Gene Summary for MRPS24 Gene

  • Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. A pseudogene corresponding to this gene is found on chromosome 11. Read-through transcription exists between this gene and the upstream upregulator of cell proliferation (URGCP) gene. [provided by RefSeq, Mar 2011]

GeneCards Summary for MRPS24 Gene

MRPS24 (Mitochondrial Ribosomal Protein S24) is a Protein Coding gene. GO annotations related to this gene include structural constituent of ribosome.

Gene Wiki entry for MRPS24 Gene

No data available for UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MRPS24 Gene

Genomics for MRPS24 Gene

Genomic Location for MRPS24 Gene

Start:
43,866,558 bp from pter
End:
43,869,893 bp from pter
Size:
3,336 bases
Orientation:
Minus strand

Genomic View for MRPS24 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MRPS24 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MRPS24 Gene

Regulatory Elements for MRPS24 Gene

Proteins for MRPS24 Gene

  • Protein details for MRPS24 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96EL2-RT24_HUMAN
    Recommended name:
    28S ribosomal protein S24, mitochondrial
    Protein Accession:
    Q96EL2
    Secondary Accessions:
    • A4D1U9
    • P82668
    • Q96Q23
    • Q9P047

    Protein attributes for MRPS24 Gene

    Size:
    167 amino acids
    Molecular mass:
    19015 Da
    Quaternary structure:
    • Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30 distinct proteins.
    SequenceCaution:
    • Sequence=AAF29013.1; Type=Frameshift; Positions=27, 45; Evidence={ECO:0000305};

neXtProt entry for MRPS24 Gene

Proteomics data for MRPS24 Gene at MOPED

Post-translational modifications for MRPS24 Gene

No Post-translational modifications

Other Protein References for MRPS24 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for MRPS24 Gene

Domains for MRPS24 Gene

Gene Families for MRPS24 Gene

HGNC:
  • MRPS :Mitochondrial ribosomal proteins / small subunits

Protein Domains for MRPS24 Gene

InterPro:
ProtoNet:
genes like me logo Genes that share domains with MRPS24: view

No data available for UniProtKB/Swiss-Prot for MRPS24 Gene

Function for MRPS24 Gene

Gene Ontology (GO) - Molecular Function for MRPS24 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003735 structural constituent of ribosome ISS --
GO:0044822 poly(A) RNA binding IDA 22658674
genes like me logo Genes that share ontologies with MRPS24: view

miRNA for MRPS24 Gene

miRTarBase miRNAs that target MRPS24

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for MRPS24 Gene

Localization for MRPS24 Gene

Subcellular locations from UniProtKB/Swiss-Prot for MRPS24 Gene

Mitochondrion.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for MRPS24 Gene COMPARTMENTS Subcellular localization image for MRPS24 gene
Compartment Confidence
mitochondrion 5
extracellular 2
cytosol 1
peroxisome 1

Gene Ontology (GO) - Cellular Components for MRPS24 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005739 mitochondrion --
GO:0005743 mitochondrial inner membrane TAS --
GO:0005762 mitochondrial large ribosomal subunit ISS --
GO:0005763 mitochondrial small ribosomal subunit NAS 10938081
genes like me logo Genes that share ontologies with MRPS24: view

Pathways for MRPS24 Gene

SuperPathways for MRPS24 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MRPS24 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006412 translation ISS --
GO:0006996 organelle organization TAS --
GO:0008150 biological_process ND --
GO:0032543 mitochondrial translation TAS --
GO:0070124 mitochondrial translational initiation TAS --
genes like me logo Genes that share ontologies with MRPS24: view

No data available for Pathways by source for MRPS24 Gene

Transcripts for MRPS24 Gene

mRNA/cDNA for MRPS24 Gene

Unigene Clusters for MRPS24 Gene

Mitochondrial ribosomal protein S24:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for MRPS24 Gene

ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5a · 5b · 5c
SP1: - - -
SP2: -
SP3: -
SP4:

Relevant External Links for MRPS24 Gene

GeneLoc Exon Structure for
MRPS24
ECgene alternative splicing isoforms for
MRPS24

Expression for MRPS24 Gene

mRNA expression in normal human tissues for MRPS24 Gene

mRNA expression in normal human tissues for MRPS24 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for MRPS24 Gene

SOURCE GeneReport for Unigene cluster for MRPS24 Gene Hs.284286

genes like me logo Genes that share expressions with MRPS24: view

Orthologs for MRPS24 Gene

This gene was present in the common ancestor of animals.

Orthologs for MRPS24 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia MRPS24 36
  • 99.4 (n)
  • 98.8 (a)
MRPS24 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia MRPS24 36
  • 84.63 (n)
  • 85.63 (a)
MRPS24 37
  • 86 (a)
OneToOne
dog
(Canis familiaris)
Mammalia MRPS24 37
  • 87 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mrps24 36
  • 84.43 (n)
  • 83.83 (a)
Mrps24 16
Mrps24 37
  • 84 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia MRPS24 37
  • 69 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia MRPS24 37
  • 71 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Mrps24 36
  • 85.23 (n)
  • 84.43 (a)
African clawed frog
(Xenopus laevis)
Amphibia Xl.17933 36
tropical clawed frog
(Silurana tropicalis)
Amphibia mrps24 36
  • 68.78 (n)
  • 69.01 (a)
zebrafish
(Danio rerio)
Actinopterygii Dr.15062 36
mrps24 36
  • 61.55 (n)
  • 61.35 (a)
mrps24 37
  • 61 (a)
OneToOne
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP012833 36
  • 52.61 (n)
  • 44.9 (a)
fruit fly
(Drosophila melanogaster)
Insecta mRpS24 36
  • 53.66 (n)
  • 43.26 (a)
mRpS24 37
  • 39 (a)
OneToOne
mRpS24 38
  • 42 (a)
worm
(Caenorhabditis elegans)
Secernentea mrps-24 36
  • 45.07 (n)
  • 36.62 (a)
mrps-24 37
  • 32 (a)
OneToOne
Species with no ortholog for MRPS24:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for MRPS24 Gene

ENSEMBL:
Gene Tree for MRPS24 (if available)
TreeFam:
Gene Tree for MRPS24 (if available)

Paralogs for MRPS24 Gene

Pseudogenes.org Pseudogenes for MRPS24 Gene

genes like me logo Genes that share paralogs with MRPS24: view

No data available for Paralogs for MRPS24 Gene

Variants for MRPS24 Gene

Sequence variations from dbSNP and Humsavar for MRPS24 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type MAF
VAR_030077 -

Structural Variations from Database of Genomic Variants (DGV) for MRPS24 Gene

Variant ID Type Subtype PubMed ID
nsv428165 CNV Gain 18775914
nsv830980 CNV Loss 17160897

Relevant External Links for MRPS24 Gene

HapMap Linkage Disequilibrium report
MRPS24

Disorders for MRPS24 Gene

Relevant External Links for MRPS24

Genetic Association Database (GAD)
MRPS24
Human Genome Epidemiology (HuGE) Navigator
MRPS24
genes like me logo Genes that share disorders with MRPS24: view

No data available for UniProtKB/Swiss-Prot for MRPS24 Gene

Publications for MRPS24 Gene

  1. Molecular characterization of the mouse ribosomal protein S24 multigene family: a uniquely expressed intron-containing gene with cell-specific expression of three alternatively spliced mRNAs. (PMID: 8127713) Xu L. … Ro H.S. (Nucleic Acids Res. 1994) 2 3 23
  2. Identification of genes expressed in human CD34(+) hematopoietic stem/progenitor cells by expressed sequence tags and efficient full- length cDNA cloning. (PMID: 9653160) Mao M. … Chen Z. (Proc. Natl. Acad. Sci. U.S.A. 1998) 3 4
  3. A proteomics approach to the identification of mammalian mitochondrial small subunit ribosomal proteins. (PMID: 10938081) Koc E.C. … Spremulli L.L. (J. Biol. Chem. 2000) 3 4
  4. The small subunit of the mammalian mitochondrial ribosome: identification of the full complement of ribosomal proteins present. (PMID: 11279123) Koc E.C. … Spremulli L.L. (J. Biol. Chem. 2001) 2 3
  5. Proteomic analysis of the mammalian mitochondrial ribosome. Identification of protein components in the 28S small subunit. (PMID: 11402041) Suzuki T. … Watanabe K. (J. Biol. Chem. 2001) 3 4

Products for MRPS24 Gene

Sources for MRPS24 Gene

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