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Aliases for MRPS24 Gene

Aliases for MRPS24 Gene

  • Mitochondrial Ribosomal Protein S24 2 3 5
  • MRP-S24 3 4
  • BMRP-47 3 4
  • BMRP47 3 4
  • S24mt 3 4
  • Mitochondrial 28S Ribosomal Protein S24 3
  • HSPC335 3

External Ids for MRPS24 Gene

Previous GeneCards Identifiers for MRPS24 Gene

  • GC07M043552
  • GC07M043646
  • GC07M043679
  • GC07M043872

Summaries for MRPS24 Gene

Entrez Gene Summary for MRPS24 Gene

  • Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. A pseudogene corresponding to this gene is found on chromosome 11. Read-through transcription exists between this gene and the upstream upregulator of cell proliferation (URGCP) gene. [provided by RefSeq, Mar 2011]

GeneCards Summary for MRPS24 Gene

MRPS24 (Mitochondrial Ribosomal Protein S24) is a Protein Coding gene. Among its related pathways are Mitochondrial translation and Organelle biogenesis and maintenance. GO annotations related to this gene include poly(A) RNA binding and structural constituent of ribosome.

Gene Wiki entry for MRPS24 Gene

No data available for UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MRPS24 Gene

Genomics for MRPS24 Gene

Regulatory Elements for MRPS24 Gene

Enhancers for MRPS24 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around MRPS24 on UCSC Golden Path with GeneCards custom track

Promoters for MRPS24 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around MRPS24 on UCSC Golden Path with GeneCards custom track

Genomic Location for MRPS24 Gene

43,866,558 bp from pter
43,869,893 bp from pter
3,336 bases
Minus strand

Genomic View for MRPS24 Gene

Genes around MRPS24 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MRPS24 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MRPS24 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MRPS24 Gene

Proteins for MRPS24 Gene

  • Protein details for MRPS24 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    28S ribosomal protein S24, mitochondrial
    Protein Accession:
    Secondary Accessions:
    • A4D1U9
    • P82668
    • Q96Q23
    • Q9P047

    Protein attributes for MRPS24 Gene

    167 amino acids
    Molecular mass:
    19015 Da
    Quaternary structure:
    • Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30 distinct proteins.
    • Sequence=AAF29013.1; Type=Frameshift; Positions=27, 45; Evidence={ECO:0000305};

    Three dimensional structures from OCA and Proteopedia for MRPS24 Gene

neXtProt entry for MRPS24 Gene

Proteomics data for MRPS24 Gene at MOPED

Post-translational modifications for MRPS24 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for MRPS24 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for MRPS24 Gene

Domains & Families for MRPS24 Gene

Gene Families for MRPS24 Gene

Protein Domains for MRPS24 Gene


Suggested Antigen Peptide Sequences for MRPS24 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MRPS24: view

No data available for UniProtKB/Swiss-Prot for MRPS24 Gene

Function for MRPS24 Gene

Phenotypes for MRPS24 Gene

GenomeRNAi human phenotypes for MRPS24:
genes like me logo Genes that share phenotypes with MRPS24: view

Animal Model Products

miRNA for MRPS24 Gene

miRTarBase miRNAs that target MRPS24

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for MRPS24 Gene

Localization for MRPS24 Gene

Subcellular locations from UniProtKB/Swiss-Prot for MRPS24 Gene


Subcellular locations from

Jensen Localization Image for MRPS24 Gene COMPARTMENTS Subcellular localization image for MRPS24 gene
Compartment Confidence
mitochondrion 5
extracellular 2
nucleus 2
cytosol 1
peroxisome 1

No data available for Gene Ontology (GO) - Cellular Components for MRPS24 Gene

Pathways & Interactions for MRPS24 Gene

genes like me logo Genes that share pathways with MRPS24: view

Gene Ontology (GO) - Biological Process for MRPS24 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006412 translation IBA --
GO:0006996 organelle organization TAS --
GO:0008150 biological_process ND --
genes like me logo Genes that share ontologies with MRPS24: view

No data available for SIGNOR curated interactions for MRPS24 Gene

Drugs & Compounds for MRPS24 Gene

No Compound Related Data Available

Transcripts for MRPS24 Gene

Unigene Clusters for MRPS24 Gene

Mitochondrial ribosomal protein S24:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for MRPS24 Gene

ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5a · 5b · 5c
SP1: - - -
SP2: -
SP3: -

Relevant External Links for MRPS24 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MRPS24 Gene

mRNA expression in normal human tissues for MRPS24 Gene

mRNA expression in normal human tissues for MRPS24 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for MRPS24 Gene

This gene is overexpressed in Pancreas (20.7), Lung (15.5), and Breast (6.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for MRPS24 Gene

SOURCE GeneReport for Unigene cluster for MRPS24 Gene Hs.284286

genes like me logo Genes that share expression patterns with MRPS24: view

Protein tissue co-expression partners for MRPS24 Gene

Primer Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for MRPS24 Gene

Orthologs for MRPS24 Gene

This gene was present in the common ancestor of animals.

Orthologs for MRPS24 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia MRPS24 35
  • 84.63 (n)
  • 85.63 (a)
MRPS24 36
  • 86 (a)
(Mus musculus)
Mammalia Mrps24 35
  • 84.43 (n)
  • 83.83 (a)
Mrps24 16
Mrps24 36
  • 84 (a)
(Pan troglodytes)
Mammalia MRPS24 35
  • 99.4 (n)
  • 98.8 (a)
MRPS24 36
  • 99 (a)
(Rattus norvegicus)
Mammalia Mrps24 35
  • 85.23 (n)
  • 84.43 (a)
(Canis familiaris)
Mammalia MRPS24 36
  • 87 (a)
(Monodelphis domestica)
Mammalia MRPS24 36
  • 69 (a)
(Ornithorhynchus anatinus)
Mammalia MRPS24 36
  • 71 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia mrps24 35
  • 68.78 (n)
  • 69.01 (a)
African clawed frog
(Xenopus laevis)
Amphibia Xl.17933 35
(Danio rerio)
Actinopterygii Dr.15062 35
mrps24 35
  • 61.55 (n)
  • 61.35 (a)
mrps24 36
  • 61 (a)
fruit fly
(Drosophila melanogaster)
Insecta mRpS24 37
  • 42 (a)
mRpS24 35
  • 53.66 (n)
  • 43.26 (a)
mRpS24 36
  • 39 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP012833 35
  • 52.61 (n)
  • 44.9 (a)
(Caenorhabditis elegans)
Secernentea mrps-24 35
  • 45.07 (n)
  • 36.62 (a)
mrps-24 36
  • 32 (a)
Species with no ortholog for MRPS24:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for MRPS24 Gene

Gene Tree for MRPS24 (if available)
Gene Tree for MRPS24 (if available)

Paralogs for MRPS24 Gene Pseudogenes for MRPS24 Gene

genes like me logo Genes that share paralogs with MRPS24: view

No data available for Paralogs for MRPS24 Gene

Variants for MRPS24 Gene

Sequence variations from dbSNP and Humsavar for MRPS24 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
VAR_030077 -

Structural Variations from Database of Genomic Variants (DGV) for MRPS24 Gene

Variant ID Type Subtype PubMed ID
nsv428165 CNV Gain 18775914
nsv830980 CNV Loss 17160897

Variation tolerance for MRPS24 Gene

Residual Variation Intolerance Score: 69% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.44; 64.00% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for MRPS24 Gene

Disorders for MRPS24 Gene

Relevant External Links for MRPS24

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MRPS24 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MRPS24 Gene

Publications for MRPS24 Gene

  1. Molecular characterization of the mouse ribosomal protein S24 multigene family: a uniquely expressed intron-containing gene with cell-specific expression of three alternatively spliced mRNAs. (PMID: 8127713) Xu L. … Ro H.S. (Nucleic Acids Res. 1994) 2 3 23 67
  2. The small subunit of the mammalian mitochondrial ribosome: identification of the full complement of ribosomal proteins present. (PMID: 11279123) Koc E.C. … Spremulli L.L. (J. Biol. Chem. 2001) 2 3
  3. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  4. LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells. (PMID: 23443559) Fogeron M.L. … Lange B.M. (Nat Commun 2013) 3
  5. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. (PMID: 22658674) Castello A. … Hentze M.W. (Cell 2012) 3

Products for MRPS24 Gene

Sources for MRPS24 Gene