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MRPS23 Gene

protein-coding   GIFtS: 52
GCID: GC17M055916

Mitochondrial Ribosomal Protein S23

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Mitochondrial Ribosomal Protein S231 2
MRP-S232 3
S23mt2 3
28S Ribosomal Protein S23, Mitochondrial2
HSPC3292

External Ids:    HGNC: 145091   Entrez Gene: 516492   Ensembl: ENSG000001816107   OMIM: 6119855   UniProtKB: Q9Y3D93   

Export aliases for MRPS23 gene to outside databases

Previous GC identifers: GC17M055658 GC17M058398 GC17M056255 GC17M056391 GC17M053271 GC17M051277


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for MRPS23 Gene:
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the
mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit.
They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is
reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain
a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and
sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a
28S subunit protein. A pseudogene corresponding to this gene is found on chromosome 7p. (provided by RefSeq, Jul
2008)

GeneCards Summary for MRPS23 Gene:
MRPS23 (mitochondrial ribosomal protein S23) is a protein-coding gene. Diseases associated with MRPS23 include sinusitis, and malaria. GO annotations related to this gene include structural constituent of ribosome.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000017.11  NC_018928.2  NT_010783.16  
Regulatory elements:
   Regulatory transcription factor binding sites in the MRPS23 gene promoter:
         AML1a   GATA-3   HSF1 (long)   MyoD   Tal-1beta   E47   AREB6   HOXA5   c-Myb   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMRPS23 promoter sequence
   Search Chromatin IP Primers for MRPS23

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MRPS23


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q22-q23   Ensembl cytogenetic band:  17q22   HGNC cytogenetic band: 17q22-q23

MRPS23 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MRPS23 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17M055916:  view genomic region     (about GC identifiers)

Start:
55,916,287 bp from pter      End:
55,927,433 bp from pter
Size:
11,147 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: RT23_HUMAN, Q9Y3D9 (See protein sequence)
Recommended Name: 28S ribosomal protein S23, mitochondrial  
Size: 190 amino acids; 21771 Da
Subunit: Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30
distinct proteins (By similarity)
Sequence caution: Sequence=AAD34133.1; Type=Frameshift; Positions=138; Sequence=AAF29007.1; Type=Frameshift;
Positions=Several;
Secondary accessions: B2R6V3 Q96Q24 Q9BWH8 Q9P053

Explore the universe of human proteins at neXtProt for MRPS23: NX_Q9Y3D9

Explore proteomics data for MRPS23 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys57, Lys108
  • Modification sites at PhosphoSitePlus

  • See MRPS23 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_057154.2  
    ENSEMBL proteins: 
     ENSP00000320184   ENSP00000463677   ENSP00000463481  

    MRPS23 Human Recombinant Protein Products:

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    OriGene Protein Over-expression Lysate for MRPS23
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    Novus Biologicals MRPS23 Protein
    Novus Biologicals MRPS23 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for MRPS23

    MRPS23 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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    OriGene Custom Antibody Services for MRPS23
    Novus Biologicals MRPS23 Antibodies
    Abcam antibodies for MRPS23
    Cloud-Clone Corp. Antibodies for MRPS23
    ThermoFisher Antibody for MRPS23
    LSBio Antibodies in human, mouse, rat for MRPS23

    MRPS23 Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    GenScript Custom Assay Services for MRPS23
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for MRPS23
    Cloud-Clone Corp. CLIAs for MRPS23


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    MRPS: Mitochondrial ribosomal proteins / small subunits

    2 InterPro protein domains:
     IPR019520 Ribosomal_S23_mit
     IPR023611 Ribosomal_S23/S25_mit

    Graphical View of Domain Structure for InterPro Entry Q9Y3D9

    ProtoNet protein and cluster: Q9Y3D9


    MRPS23 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003735structural constituent of ribosome IEA--
    GO:0044822poly(A) RNA binding IDA--
         
    MRPS23 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for MRPS23:
     Decreased viability of wild-ty 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for MRPS23
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for MRPS23
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for MRPS23

    miRNA
    Products:
        
    miRTarBase miRNAs that target MRPS23:
    hsa-mir-92b-3p (MIRT040709), hsa-mir-503-5p (MIRT041099), hsa-mir-181b-5p (MIRT047269), hsa-mir-16-5p (MIRT031963)

    Block miRNA regulation of human, mouse, rat MRPS23 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate MRPS23 (see all 15):
    hsa-miR-548w hsa-miR-548j hsa-miR-559 hsa-miR-548i hsa-miR-548h hsa-miR-548c-5p hsa-miR-513a-3p hsa-miR-548y
    SwitchGear 3'UTR luciferase reporter plasmidMRPS23 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for MRPS23
    Predesigned siRNA for gene silencing in human, mouse, rat MRPS23

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for MRPS23

    Clone
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    OriGene clones in human, mouse for MRPS23 (see all 5)
    OriGene ORF clones in mouse, rat for MRPS23
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: MRPS23 (NM_016070)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MRPS23
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MRPS23

    Cell Line
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    GenScript Custom overexpressing Cell Line Services for MRPS23
    Browse ESI BIO Cell Lines and PureStem Progenitors for MRPS23 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MRPS23


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    RT23_HUMAN, Q9Y3D9: Mitochondrion
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    mitochondrion5
    cytoskeleton4
    nucleus4
    cytosol2
    extracellular1

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion IDA--
    GO:0005840ribosome IEA--
    GO:0031965nuclear membrane IDA--
    GO:0045111intermediate filament cytoskeleton IDA--

    MRPS23 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for MRPS23
    Interactions:

        Search GeneGlobe Interaction Network for MRPS23

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    Selected Interacting proteins for MRPS23 (Q9Y3D92, 3 ENSP000003201844) via UniProtKB, MINT, STRING, and/or I2D (see all 315)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ICT1Q141972, 3, ENSP000003015854MINT-8079030 I2D: score=1 STRING: ENSP00000301585
    ATG12O948173, ENSP000002744594I2D: score=1 STRING: ENSP00000274459
    SRRM2Q9UQ353, ENSP000003017404I2D: score=1 STRING: ENSP00000301740
    AGO1Q9UL182, ENSP000003623004MINT-6488590 STRING: ENSP00000362300
    ATP5C1P365422MINT-6488590 MINT-8079030
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006412translation IEA--

    MRPS23 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for MRPS23 (RT23)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for MRPS23 gene: 
    NM_016070.3  

    Unigene Cluster for MRPS23:

    Mitochondrial ribosomal protein S23
    Hs.5836  [show with all ESTs]
    Unigene Representative Sequence: NM_016070
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000313608(uc002ivc.3) ENST00000578444 ENST00000579380 ENST00000579768

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat MRPS23 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate MRPS23 (see all 15):
    hsa-miR-548w hsa-miR-548j hsa-miR-559 hsa-miR-548i hsa-miR-548h hsa-miR-548c-5p hsa-miR-513a-3p hsa-miR-548y
    SwitchGear 3'UTR luciferase reporter plasmidMRPS23 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for MRPS23
    Predesigned siRNA for gene silencing in human, mouse, rat MRPS23
    Clone
    Products:
         
    OriGene clones in human, mouse for MRPS23 (see all 5)
    OriGene ORF clones in mouse, rat for MRPS23
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: MRPS23 (NM_016070)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MRPS23
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MRPS23
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for MRPS23
    OriGene qSTAR qPCR primer pairs in human, mouse for MRPS23
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat MRPS23
      QuantiTect SYBR Green Assays in human, mouse, rat MRPS23
      QuantiFast Probe-based Assays in human, mouse, rat MRPS23

    Additional mRNA sequence: 

    AF151896.1 AF161447.1 AK312729.1 BC000242.1 

    6 DOTS entries:

    DT.418245  DT.97808768  DT.100819788  DT.100819787  DT.120916692  DT.121612321 

    Selected AceView cDNA sequences (see all 235):

    BU159018 BQ028104 AA548767 BM669718 BG750539 AW299554 CB159786 AA772038 
    BE351063 BU627075 AA587106 BM424104 AI124037 BM985370 BG284005 BC000242 
    BQ924026 AA775847 CR622139 AI340281 AA992182 AA939335 N34606 CA423989 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for MRPS23    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b ^ 5a · 5b
    SP1:                                -               
    SP2:                                                
    SP3:                                -               


    ECgene alternative splicing isoforms for MRPS23

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    MRPS23 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AAGAAACCTT
    MRPS23 Expression
    About this image


    MRPS23 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Intermediate Mesoderm (Gastrulation Derivatives)
             Mesonephros
     
     Thyroid (Endocrine System)
     
     Testis (Reproductive System)
     
     Prostate (Endocrine System)
    MRPS23 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    MRPS23 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.5836
        Custom PCR Arrays for MRPS23
    Primer
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    OriGene qPCR primer pairs and template standards for MRPS23
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    QuantiFast Probe-based Assays in human, mouse, rat MRPS23
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MRPS23

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for MRPS23 gene from Selected species (see all 17)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Mrps231 , 5 mitochondrial ribosomal protein S231, 5 82.8(n)1
    82.17(a)1
      11 (52.40 cM)5
    646561  NM_024174.51  NP_077136.21 
     882043885 
    chicken
    (Gallus gallus)
    Aves MRPS231 mitochondrial ribosomal protein S23 58.19(n)
    54.8(a)
      417666  XM_003642415.2  XP_003642463.1 
    lizard
    (Anolis carolinensis)
    Reptilia MRPS236
    mitochondrial ribosomal protein S23
    51(a)
    1 ↔ 1
    GL344147.1(19601-30098)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.300062 Xenopus laevis transcribed sequence with weak similarity more 70.81(n)    BG345440.1 
    zebrafish
    (Danio rerio)
    Actinopterygii mrps231 mitochondrial ribosomal protein S23 58.13(n)
    53.57(a)
      445221  NM_001003615.1  NP_001003615.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta mRpS231 mitochondrial Ribosomal protein S23 52.62(n)
    44.63(a)
      318977  NM_165065.3  NP_723847.1 
    worm
    (Caenorhabditis elegans)
    Secernentea mrps-236
    Protein MRPS-23 (mrps-23) mRNA, complete cds
    36(a)
    1 ↔ 1
    III(9523113-9523708) WBGene00014224


    ENSEMBL Gene Tree for MRPS23 (if available)
    TreeFam Gene Tree for MRPS23 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for MRPS23 gene

    MRPS23 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for MRPS23
    PGOHUM00000233212


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for MRPS23 (see all 324)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs99086681,2
    C,F,A,H--55915940(+) TGTCTT/CTGAAT 1 -- ds500135Minor allele frequency- C:0.29NA NS EA WA CSA 3331
    rs1402724391,2
    --55915967(+) CCTACG/TGAAAA 1 -- ds50010--------
    rs1874102201,2
    --55915974(+) AAAAGA/TAAAGC 1 -- ds50010--------
    rs758461581,2
    F--55916024(+) TCGAGA/GGGGAA 1 -- ds50010--------
    rs1378749531,2
    --55916061(+) CTAATA/GTATTC 1 -- ds50010--------
    rs1423806991,2
    C--55916156(+) CAGGAA/GAGATG 1 -- ds50010--------
    rs25860371,2
    C,F,O,A,H--55916165(+) TGAGAC/GCATAC 1 -- ds500123Minor allele frequency- G:0.09NA NS EA WA CSA 1762
    rs26854871,2
    C,F,A,H--55916379(-) TGCCTC/TCCTGG 1 -- ut3125Minor allele frequency- T:0.46EA NS NA CSA WA 4258
    rs1431835231,2
    --55916408(+) GCATCA/CCCTAA 1 -- ut310--------
    rs1482836541,2
    --55916513(+) AAGTAC/TTTACT 1 -- ut310--------

    HapMap Linkage Disequilibrium report for MRPS23 (55916287 - 55927433 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for MRPS23:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv272079CNV Insertion20981092
    nsv819589CNV Loss19587683

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing MRPS23
    DNA2.0 Custom Variant and Variant Library Synthesis for MRPS23

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 611985    OMIM disorders: --

    2 diseases for MRPS23:    
    About MalaCards
    sinusitis    malaria


    MRPS23 for disorders           About GeneDecksing

    Genetic Association Database (GAD): MRPS23
    Human Genome Epidemiology (HuGE) Navigator: MRPS23 (2 documents)

    Export disorders for MRPS23 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for MRPS23 gene, integrated from 10 sources (see all 25):
    (articles sorted by number of sources associating them with MRPS23)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    2. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (PLoS ONE 2010)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. The human mitochondrial ribosomal protein genes: mapping of 54 genes to the chromosomes and implications for human disorders. (PubMed id 11543634)1, 2 Kenmochi N.... Tanaka T. (Genomics 2001)
    5. The small subunit of the mammalian mitochondrial ribosome: identification of the full complement of ribosomal proteins present. (PubMed id 11279123)1, 3 Koc E.C.... Spremulli L.L. (J. Biol. Chem. 2001)
    6. A proteomics approach to the identification of mammalian mitochondrial small subunit ribosomal proteins. (PubMed id 10938081)1, 2 Koc E.C....Spremulli L.L. (J. Biol. Chem. 2000)
    7. Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics. (PubMed id 10810093)1, 2 Lai C.-H.... Lin W.-C. (Genome Res. 2000)
    8. Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS. (PubMed id 23455922)1 Varjosalo M....Superti-Furga G. (Nat. Methods 2013)
    9. Deubiquitinase FAM/USP9X interacts with the E3 ubiquitin ligase SMURF1 protein and protects it from ligase activity-dependent self-degradation. (PubMed id 23184937)1 Xie Y....Cong F. (J. Biol. Chem. 2013)
    10. Profiling of Parkin-binding partners using tandem affinity purification. (PubMed id 24244333)1 Zanon A....Pichler I. (PLoS ONE 2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
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      Query String
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    OMIM
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 51649 HGNC: 14509 AceView: MRPS23 Ensembl:ENSG00000181610 euGenes: HUgn51649
    ECgene: MRPS23 H-InvDB: MRPS23

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for MRPS23 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for MRPS23 gene:
    Search GeneIP for patents involving MRPS23

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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