Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



MRPS18C Gene

protein-coding   GIFtS: 51
GCID: GC04P084301

Mitochondrial Ribosomal Protein S18C

  Search for MRPS18C
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

This gene clusters with an RNA gene
Subcategory (RNA class): antisense

Quality score for the ORGUL clustered with this gene is 3

Aliases
Mitochondrial Ribosomal Protein S18C1 2     MRPS18-12 5
28S Ribosomal Protein S18-1, Mitochondrial2 3     28S Ribosomal Protein S18c, Mitochondrial2
MRP-S18-12 3     Mitochondrial Ribosomal Protein S18-12
MRP-S18-c2 3     mrps18-c2
S18mt-c2 3     Mrps18-c3

External Ids:    HGNC: 166331   Entrez Gene: 510232   Ensembl: ENSG000001633197   OMIM: 6119835   UniProtKB: Q9Y3D53   
ORGUL members:         

Export aliases for MRPS18C gene to outside databases

Previous GC identifers: GC04P084670 GC04P084835 GC04P084734 GC04P084596 GC04P080119


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

Entrez Gene summary for MRPS18C Gene:
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the
mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit.
They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is
reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain
a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and
sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a
28S subunit protein that belongs to the ribosomal protein S18P family. The encoded protein is one of three that
has significant sequence similarity to bacterial S18 proteins. The primary sequences of the three human
mitochondrial S18 proteins are no more closely related to each other than they are to the prokaryotic S18
proteins. Pseudogenes corresponding to this gene are found on chromosomes 8p, 12p, 15q, and 22q. (provided by
RefSeq, Jul 2008)

GeneCards Summary for MRPS18C Gene:
MRPS18C (mitochondrial ribosomal protein S18C) is a protein-coding gene. GO annotations related to this gene include structural constituent of ribosome.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence at NCBI GenBank:
NC_000004.11  NT_016354.20  NC_018915.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the MRPS18C gene promoter:
         AhR   AML1a   FOXF2   p53   Pax-6   NF-kappaB   GATA-1   Arnt   NF-kappaB2   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMRPS18C promoter sequence
   Search Chromatin IP Primers for MRPS18C

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MRPS18C


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4q21.23   Ensembl cytogenetic band:  4q21.23   HGNC cytogenetic band: 4q21.21-q21.23

MRPS18C Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MRPS18C gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04P084301:  view genomic region     (about GC identifiers)

Start:
84,377,085 bp from pter      End:
84,390,888 bp from pter
Size:
13,804 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: RT18C_HUMAN, Q9Y3D5 (See protein sequence)
Recommended Name: 28S ribosomal protein S18c, mitochondrial precursor  
Size: 142 amino acids; 15850 Da
Subunit: Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30
distinct proteins

Explore the universe of human proteins at neXtProt for MRPS18C: NX_Q9Y3D5

Explore proteomics data for MRPS18C at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys125
  • Modification sites at PhosphoSitePlus

  • See MRPS18C Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_057151.1  
    ENSEMBL proteins: 
     ENSP00000295491   ENSP00000427169   ENSP00000426930   ENSP00000427014   ENSP00000425268  

    MRPS18C Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for MRPS18C
    OriGene Protein Over-expression Lysate for MRPS18C
    OriGene MassSpec for MRPS18C
    OriGene Custom Protein Services for MRPS18C
    GenScript Custom Purified and Recombinant Proteins Services for MRPS18C
    Novus Biologicals MRPS18C Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for MRPS18C

     
    Search eBioscience for Proteins for MRPS18C 

    MRPS18C Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    OriGene Antibodies for MRPS18C
    OriGene Custom Antibody Services for MRPS18C
    Novus Biologicals MRPS18C Antibodies
    Abcam antibodies for MRPS18C
    Cloud-Clone Corp. Antibodies for MRPS18C
    ThermoFisher Antibody for MRPS18C
    LSBio Antibodies in human, mouse, rat for MRPS18C

    MRPS18C Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for MRPS18C
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for MRPS18C
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for MRPS18C
    Cloud-Clone Corp. CLIAs for MRPS18C
    Search eBioscience for ELISAs for MRPS18C 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    HGNC Gene Families:
    MRPS: Mitochondrial ribosomal proteins / small subunits

    2 InterPro protein domains:
     IPR018275 Ribosomal_S18_CS
     IPR001648 Ribosomal_S18

    Graphical View of Domain Structure for InterPro Entry Q9Y3D5

    ProtoNet protein and cluster: Q9Y3D5

    1 Blocks protein domain: IPB001648 Ribosomal protein S18

    UniProtKB/Swiss-Prot: RT18C_HUMAN, Q9Y3D5
    Similarity: Belongs to the ribosomal protein S18P family


    Find genes that share domains with MRPS18C           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003735structural constituent of ribosome NAS11279123
         
    Find genes that share ontologies with MRPS18C           About GenesLikeMe


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for MRPS18C
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for MRPS18C

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for MRPS18C
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for MRPS18C

    miRNA
    Products:
        
    Block miRNA regulation of human, mouse, rat MRPS18C using miScript Target Protectors
    4 qRT-PCR Assays for microRNAs that regulate MRPS18C:
    hsa-miR-1283 hsa-miR-3143 hsa-miR-556-5p hsa-miR-543
    SwitchGear 3'UTR luciferase reporter plasmidMRPS18C 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for MRPS18C
    Predesigned siRNA for gene silencing in human, mouse, rat MRPS18C

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for MRPS18C

    Clone
    Products:
         
    OriGene clones in human, mouse for MRPS18C (see all 7)
    OriGene ORF clones in mouse, rat for MRPS18C
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: MRPS18C (NM_016067)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MRPS18C
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MRPS18C

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for MRPS18C
    Browse ESI BIO Cell Lines and PureStem Progenitors for MRPS18C 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MRPS18C


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    RT18C_HUMAN, Q9Y3D5: Mitochondrion
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    mitochondrion5
    extracellular2
    cytosol1
    nucleus1

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005739mitochondrion ----
    GO:0005763mitochondrial small ribosomal subunit IDA11279123
    GO:0005840ribosome ----

    Find genes that share ontologies with MRPS18C           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus

    SuperPaths for MRPS18C About    
    See pathways by source

    SuperPathContained pathways About
    1CFTR translational fidelity class I mutations
    Ribosome0.54


    Find genes that share SuperPaths with MRPS18C           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    1 Kegg Pathway  (Kegg details for MRPS18C):
        Ribosome

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for MRPS18C
    Interactions:

        Search GeneGlobe Interaction Network for MRPS18C

    STRING Interaction Network Preview (showing 5 interactants - click image to see 18)

    Selected Interacting proteins for MRPS18C (ENSP000002954914) via UniProtKB, MINT, STRING, and/or I2D (see all 18)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    DAP3ENSP000003416924STRING: ENSP00000341692
    MRPS10ENSP000000534684STRING: ENSP00000053468
    MRPS9ENSP000002584554STRING: ENSP00000258455
    METTL17ENSP000003724454STRING: ENSP00000372445
    MRPS12ENSP000003088454STRING: ENSP00000308845
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006412translation NAS11279123

    Find genes that share ontologies with MRPS18C           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for MRPS18C (RT18C)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for MRPS18C gene: 
    NM_016067.2  

    Unigene Cluster for MRPS18C:

    Mitochondrial ribosomal protein S18C
    Hs.436161  [show with all ESTs]
    Unigene Representative Sequence: NM_016067
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000512375 ENST00000295491(uc003hor.4) ENST00000507019 ENST00000507349
    ENST00000509970 ENST00000505719 ENST00000505525 ENST00000514581 ENST00000509571

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat MRPS18C using miScript Target Protectors
    4 qRT-PCR Assays for microRNAs that regulate MRPS18C:
    hsa-miR-1283 hsa-miR-3143 hsa-miR-556-5p hsa-miR-543
    SwitchGear 3'UTR luciferase reporter plasmidMRPS18C 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for MRPS18C
    Predesigned siRNA for gene silencing in human, mouse, rat MRPS18C
    Clone
    Products:
         
    OriGene clones in human, mouse for MRPS18C (see all 7)
    OriGene ORF clones in mouse, rat for MRPS18C
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: MRPS18C (NM_016067)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MRPS18C
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MRPS18C
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for MRPS18C
    OriGene qSTAR qPCR primer pairs in human, mouse for MRPS18C
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat MRPS18C
      QuantiTect SYBR Green Assays in human, mouse, rat MRPS18C
      QuantiFast Probe-based Assays in human, mouse, rat MRPS18C

    Additional mRNA sequence: 

    AF151892.1 AK026620.1 BC005186.1 

    14 DOTS entries:

    DT.444592  DT.121274550  DT.75103561  DT.100789227  DT.91909191  DT.91956513  DT.121274496  DT.121279941 
    DT.91761919  DT.95247485  DT.121274504  DT.121485911  DT.97804758  DT.100036787 

    Selected AceView cDNA sequences (see all 152):

    AI738767 BX510154 BE738411 BF062776 C01486 BM768424 BM725559 AA236425 
    NM_016067 AA923646 AF151892 AI696129 AA853322 T39578 D12141 BQ013237 
    BU165546 BQ067910 AK002008 BU542203 D31408 AI522092 BX281462 T40674 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    MRPS18C expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TAGATTATAA
    MRPS18C Expression
    About this image


    MRPS18C expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Lung (Respiratory System)
             Trachea
     
     Limb (Muscoskeletal System)
             Autopod
     
     Neural Tube (Nervous System)
             Metencephalon
     
     Brain (Nervous System)
             Choroid Plexus
    MRPS18C Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    MRPS18C Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.436161
        Custom PCR Arrays for MRPS18C
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for MRPS18C
    OriGene qSTAR qPCR primer pairs in human, mouse for MRPS18C
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat MRPS18C
    QuantiTect SYBR Green Assays in human, mouse, rat MRPS18C
    QuantiFast Probe-based Assays in human, mouse, rat MRPS18C
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MRPS18C

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of animals.

    Orthologs for MRPS18C gene from Selected species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Mrps18c1 , 5 mitochondrial ribosomal protein S18C1, 5 86.09(n)1
    82.01(a)1
      5 (48.52 cM)5
    687351  NM_026826.11  NP_081102.11 
     1007986275 
    chicken
    (Gallus gallus)
    Aves MRPS18C1 mitochondrial ribosomal protein S18C 65.64(n)
    61.54(a)
      770813  NM_001252311.1  NP_001239240.1 
    lizard
    (Anolis carolinensis)
    Reptilia MRPS18C6
    mitochondrial ribosomal protein S18C
    73(a)
    1 ↔ 1
    5(43360678-43361941)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.205692 Xenopus laevis transcribed sequence with weak similarity more 84.33(n)    48024520 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.142732 Transcribed sequence with weak similarity to protein more 70.69(n)    57072362 
    fruit fly
    (Drosophila melanogaster)
    Insecta mRpS18C1 mitochondrial ribosomal protein S18C 53.76(n)
    53.76(a)
      43609  NM_079854.2  NP_524593.1 
    worm
    (Caenorhabditis elegans)
    Secernentea T14B4.21 T14B4.2 57.25(n)
    48.91(a)
      188492  NM_062973.3  NP_495374.1 


    ENSEMBL Gene Tree for MRPS18C (if available)
    TreeFam Gene Tree for MRPS18C (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for MRPS18C gene

    Find genes that share paralogs with MRPS18C           About GenesLikeMe


    Selected Pseudogenes.org Pseudogenes for MRPS18C (see all 6)
    PGOHUM00000239684 PGOHUM00000251169 PGOHUM00000246350 PGOHUM00000249225 PGOHUM00000249584


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for MRPS18C (see all 64)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 4 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs68315951,2
    C,H--84376743(+) CGGGCT/ACGAGC 1 -- us2k117Minor allele frequency- A:0.00NS EA NA WA CSA EU 6543
    rs1440997911,2
    --84379116(+) AATACG/TTGATA 1 -- int10--------
    rs359564681,2
    C,F--84379260(+) CTTATC/TAGACA 1 -- int13Minor allele frequency- T:0.33NA 6
    rs1922616641,2
    C--84379394(+) AGTAAA/GAAAGG 1 -- int10--------
    rs1843115641,2
    --84379401(+) AAGGTA/GTAACT 1 -- int10--------
    rs1482109471,2
    C--84379627(+) CTTCT-/GATA  
            
    GATCT
    1 -- int10--------
    rs1892630811,2
    --84379637(+) ATCTGC/TTTAAA 1 -- int10--------
    rs769144351,2
    F--84379664(+) TATAGC/GAGGCT 1 -- int11Minor allele frequency- G:0.10WA 118
    rs754500521,2
    F--84379699(+) ACTTCA/GTAATT 1 -- int11Minor allele frequency- G:0.09WA 118
    rs68523061,2
    C,F,H--84379720(+) TTATAA/GTTCTA 1 -- int110Minor allele frequency- G:0.16NA NS EA WA 664

    HapMap Linkage Disequilibrium report for MRPS18C (84377085 - 84390888 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for MRPS18C:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv829992CNV Loss17160897
    nsv829994CNV Loss17160897
    nsv879512CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing MRPS18C
    DNA2.0 Custom Variant and Variant Library Synthesis for MRPS18C

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    OMIM gene information: 611983    OMIM disorders: --


    Find genes that share disorders with MRPS18C           About GenesLikeMe

    Genetic Association Database (GAD): MRPS18C
    Human Genome Epidemiology (HuGE) Navigator: MRPS18C (2 documents)

    Export disorders for MRPS18C gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for MRPS18C gene, integrated from 10 sources (see all 14):
    (articles sorted by number of sources associating them with MRPS18C)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The small subunit of the mammalian mitochondrial ribosome: identification of the full complement of ribosomal proteins present. (PubMed id 11279123)1, 2, 3 Koc E.C.... Spremulli L.L. (J. Biol. Chem. 2001)
    2. Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics. (PubMed id 10810093)1, 2, 3 Lai C.-H.... Lin W.-C. (Genome Res. 2000)
    3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    4. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (PLoS ONE 2010)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (amp 2012)
    7. Charting the landscape of tandem BRCT domain-mediated protein interactions. (PubMed id 22990118)1 Woods N.T....Monteiro A.N. (Sci Signal 2012)
    8. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    9. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    10. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (Genomics 2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 51023 HGNC: 16633 AceView: MRPS18C Ensembl:ENSG00000163319 euGenes: HUgn51023
    ECgene: MRPS18C Kegg: 51023 H-InvDB: MRPS18C

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for MRPS18C Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for MRPS18C gene:
    Search GeneIP for patents involving MRPS18C

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     OriGene Antibodies for MRPS18C   OriGene RNAi products in human, mouse, rat for MRPS18C  
     OriGene qPCR primer pairs and template standards for MRPS18C   OriGene Protein Over-expression Lysate for MRPS18C  
     OriGene MassSpec something-or-other for MRPS18C   OriGene clones in human, mouse for MRPS18C  
     OriGene qSTAR qPCR primer pairs in human, mouse for MRPS18C   OriGene Purified Protein for MRPS18C  
     OriGene ORF clones in mouse, rat for MRPS18C   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for MRPS18C   OriGene Custom Protein Services for MRPS18C  

     
     
     Block miRNA regulation of human, mouse, rat MRPS18C using miScript Target Protectors SeqTarget long-range PCR primers for resequencing MRPS18C
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MRPS18C Predesigned siRNA for gene silencing in human, mouse, rat MRPS18C
     QuantiFast Probe-based Assays in human, mouse, rat MRPS18C QuantiTect SYBR Green Assays in human, mouse, rat MRPS18C
     Custom PCR Arrays for MRPS18C Search Chromatin IP Primers for MRPS18C
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat MRPS18C  Search GeneGlobe Interaction Network for MRPS18C
     Regulatory tfbs in MRPS18C promoter
     GenScript Custom Purified and Recombinant Proteins Services for MRPS18C GenScript cDNA clones with any tag delivered in your preferred vector for MRPS18C
     GenScript Custom Assay Services for MRPS18C GenScript Custom overexpressing Cell Line Services for MRPS18C
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for MRPS18C (RT18C)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     MRPS18C antibodies
     MRPS18C lysates
     Antibodies for MRPS18C
     See all of Abcam's Antibodies, Kits and Proteins for MRPS18C
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for MRPS18C
     Antibodies for MRPS18C
     ELISAs for MRPS18C
     CLIAs for MRPS18C



     Browse ESI BIO Cell Lines and PureStem Progenitors for MRPS18C
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MRPS18C
     SwitchGear 3'UTR luciferase reporter plasmids for MRPS18C
     SwitchGear Promoter luciferase reporter plasmids for MRPS18C
     ThermoFisher Antibody for MRPS18C
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MRPS18C
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for MRPS18C
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for MRPS18C
     LSBio Antibodies in human, mouse, rat for MRPS18C
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
     Search Addgene for plasmids for MRPS18C
      Search eBioscience for proteins for MRPS18C
      Search eBioscience for elisas for MRPS18C
      eBioscience FlowRNA Probe Sets
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      MRPS18C gene at Home site.
    Version: 3.12.212 17 Sep 2014
    hostname: 356977-web1.xennexinc.com index build: 128 solr: 1.4