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MRPS16 Gene

protein-coding   GIFtS: 59
GCID: GC10M075008

Mitochondrial Ribosomal Protein S16

  See MRPS16-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Mitochondrial Ribosomal Protein S161 2
MRP-S162 3
RPMS162 3
S16mt2 3
COXPD22 5
28S Ribosomal Protein S16, Mitochondrial2

External Ids:    HGNC: 140481   Entrez Gene: 510212   Ensembl: ENSG000001821807   OMIM: 6092045   UniProtKB: Q9Y3D33   

Export aliases for MRPS16 gene to outside databases

Previous GC identifers: GC10M073787 GC10M074105 GC10M074900 GC10M074347 GC10M074353 GC10M074672 GC10M074680 GC10M069002


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for MRPS16 Gene:
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the
mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit.
They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is
reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain
a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and
sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a
28S subunit protein that belongs to the ribosomal protein S16P family. The encoded protein is one of the most
highly conserved ribosomal proteins between mammalian and yeast mitochondria. Three pseudogenes (located at
8q21.3, 20q13.32, 22q12-q13.1) for this gene have been described. (provided by RefSeq, Jul 2008)

GeneCards Summary for MRPS16 Gene:
MRPS16 (mitochondrial ribosomal protein S16) is a protein-coding gene. Diseases associated with MRPS16 include combined oxidative phosphorylation deficiency 2, and subcortical band heterotopia. GO annotations related to this gene include structural constituent of ribosome.

Gene Wiki entry for MRPS16 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000010.11  NC_018921.2  NT_030059.14  
Regulatory elements:
   Regulatory transcription factor binding sites in the MRPS16 gene promoter:
         AhR   SRF   AML1a   SRF (504 AA)   STAT5A   Nkx2-5   CUTL1   Arnt   AREB6   NRF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMRPS16 promoter sequence
   Search Chromatin IP Primers for MRPS16

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MRPS16


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q22.1   Ensembl cytogenetic band:  10q22.2   HGNC cytogenetic band: 10q22.1

MRPS16 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MRPS16 gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10M075008:  view genomic region     (about GC identifiers)

Start:
75,006,510 bp from pter      End:
75,012,451 bp from pter
Size:
5,942 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: RT16_HUMAN, Q9Y3D3 (See protein sequence)
Recommended Name: 28S ribosomal protein S16, mitochondrial precursor  
Size: 137 amino acids; 15345 Da
Subunit: Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30
distinct proteins
Secondary accessions: Q96Q60

Explore the universe of human proteins at neXtProt for MRPS16: NX_Q9Y3D3

Explore proteomics data for MRPS16 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys64
  • Modification sites at PhosphoSitePlus

  • See MRPS16 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_057149.1  
    ENSEMBL proteins: 
     ENSP00000362036   ENSP00000362031   ENSP00000408812  

    MRPS16 Human Recombinant Protein Products:

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    Search eBioscience for ELISAs for MRPS16 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    MRPS: Mitochondrial ribosomal proteins / small subunits

    2 InterPro protein domains:
     IPR000307 Ribosomal_S16
     IPR023803 Ribosomal_S16_dom

    Graphical View of Domain Structure for InterPro Entry Q9Y3D3

    ProtoNet protein and cluster: Q9Y3D3

    1 Blocks protein domain: IPB000307 Ribosomal protein S16

    UniProtKB/Swiss-Prot: RT16_HUMAN, Q9Y3D3
    Similarity: Belongs to the ribosomal protein S16P family


    Find genes that share domains with MRPS16           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003735structural constituent of ribosome NAS11279123
    GO:0005515protein binding IPI19945174
         
    Find genes that share ontologies with MRPS16           About GenesLikeMe


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for MRPS16
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for MRPS16

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for MRPS16
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for MRPS16

    miRNA
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    miRTarBase miRNAs that target MRPS16:
    hsa-mir-197-3p (MIRT048083), hsa-mir-935 (MIRT036669), hsa-mir-744-5p (MIRT037587), hsa-mir-26b-5p (MIRT029903), hsa-mir-30c-5p (MIRT047902), hsa-mir-186-5p (MIRT045285)

    Block miRNA regulation of human, mouse, rat MRPS16 using miScript Target Protectors
    3 qRT-PCR Assays for microRNAs that regulate MRPS16:
    hsa-miR-136 hsa-miR-561 hsa-miR-4252
    SwitchGear 3'UTR luciferase reporter plasmidMRPS16 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for MRPS16
    Predesigned siRNA for gene silencing in human, mouse, rat MRPS16

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    GenScript: all cDNA clones in your preferred vector: MRPS16 (NM_016065)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MRPS16
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MRPS16

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MRPS16


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    RT16_HUMAN, Q9Y3D3: Mitochondrion
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    mitochondrion5
    peroxisome2
    cytosol1
    extracellular1

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005739mitochondrion ----
    GO:0005763mitochondrial small ribosomal subunit IDA11279123
    GO:0005840ribosome ----

    Find genes that share ontologies with MRPS16           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for MRPS16 About    
    See pathways by source

    SuperPathContained pathways About
    1CFTR translational fidelity class I mutations
    Ribosome0.54


    Find genes that share SuperPaths with MRPS16           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    1 Kegg Pathway  (Kegg details for MRPS16):
        Ribosome

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for MRPS16
    Interactions:

        Search GeneGlobe Interaction Network for MRPS16

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for MRPS16 (Q9Y3D32, 3 ENSP000003620364) via UniProtKB, MINT, STRING, and/or I2D (see all 384)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MRPS15P829142, ENSP000003622084MINT-6488590 MINT-8079030 STRING: ENSP00000362208
    MRPS5P826752, ENSP000002724184MINT-6488590 MINT-8079030 STRING: ENSP00000272418
    ICT1Q141972, 3, ENSP000003015854MINT-8079030 I2D: score=1 STRING: ENSP00000301585
    PHLDA3Q9Y5J53, ENSP000003562784I2D: score=1 STRING: ENSP00000356278
    SLX4Q8IY923, ENSP000002940084I2D: score=1 STRING: ENSP00000294008
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006412translation NAS11279123

    Find genes that share ontologies with MRPS16           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for MRPS16 (RT16)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for MRPS16 gene: 
    NM_016065.3  

    Unigene Cluster for MRPS16:

    Mitochondrial ribosomal protein S16
    Hs.180312  [show with all ESTs]
    Unigene Representative Sequence: NM_016065
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000479005 ENST00000372945(uc001jts.1 uc001jtt.1) ENST00000372940
    ENST00000471251 ENST00000473427 ENST00000416782(uc010qkh.1)
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat MRPS16 using miScript Target Protectors
    3 qRT-PCR Assays for microRNAs that regulate MRPS16:
    hsa-miR-136 hsa-miR-561 hsa-miR-4252
    SwitchGear 3'UTR luciferase reporter plasmidMRPS16 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for MRPS16
    Predesigned siRNA for gene silencing in human, mouse, rat MRPS16
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    OriGene clones in human, mouse for MRPS16 (see all 7)
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    GenScript: all cDNA clones in your preferred vector: MRPS16 (NM_016065)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MRPS16
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MRPS16
    Primer
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    OriGene qPCR primer pairs and template standards for MRPS16
    OriGene qSTAR qPCR primer pairs in human, mouse for MRPS16
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat MRPS16
      QuantiTect SYBR Green Assays in human, mouse, rat MRPS16
      QuantiFast Probe-based Assays in human, mouse, rat MRPS16

    Additional mRNA sequence: 

    AB049948.1 AF151890.1 AK025715.1 AK098291.1 BC021106.1 

    12 DOTS entries:

    DT.101984294  DT.100650604  DT.100045726  DT.415309  DT.95265506  DT.95265511  DT.121301469  DT.97764748 
    DT.100643557  DT.100646722  DT.121301313  DT.121301383 

    Selected AceView cDNA sequences (see all 445):

    BG818234 AA729412 BM999982 AI251857 BX448626 AI203347 BM768744 BM472254 
    BG028612 BF063763 AI804168 BE327444 AA602701 BX646217 AA581180 AI160900 
    AI567862 BQ007526 AI091910 AA746286 BQ954888 AA194114 AA557370 BQ690887 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for MRPS16 (see all 6)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b · 3c ^ 4a · 4b · 4c ^ 5 ^ 6 ^ 7 ^ 8
    SP1:                          -     -           -                                             
    SP2:                          -     -           -     -     -     -                           
    SP3:                          -                 -                                             
    SP4:                                -           -                                             
    SP5:                                                                                          


    ECgene alternative splicing isoforms for MRPS16

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    MRPS16 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGTTTTAAAA
    MRPS16 Expression
    About this image


    MRPS16 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 5) fully expand
     
     Brain (Nervous System)    fully expand to see all 2 entries
             Cerebral Cortex
     
     Trophoblast (Extraembryonic Tissues)
             Trophoblast Cells Trophoblast
     
     Ovary (Reproductive System)
             Oviduct
     
     Pancreas (Endocrine System)
             Islets of Langerhans
     
     Testis (Reproductive System)
             Leydig Cells Testis Interstitium
    MRPS16 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    MRPS16 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.180312
        Custom PCR Arrays for MRPS16
    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MRPS16

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for MRPS16 gene from Selected species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Mrps161 , 5 mitochondrial ribosomal protein S161, 5 84.69(n)1
    91.11(a)1
      14 (11.53 cM)5
    662421  NM_025440.21  NP_079716.11 
     203912315 
    chicken
    (Gallus gallus)
    Aves MRPS161 mitochondrial ribosomal protein S16 64.38(n)
    67.94(a)
      769996  XM_004950089.1  XP_004950146.1 
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.112772 Transcribed sequence with weak similarity to protein more 75.61(n)    137724240 
    zebrafish
    (Danio rerio)
    Actinopterygii BQ450690.12   -- 71.67(n)    BQ450690.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta mRpS161 mitochondrial ribosomal protein S16 55.96(n)
    51.38(a)
      36570  NM_001274038.1  NP_001260967.1 
    worm
    (Caenorhabditis elegans)
    Secernentea mrps-161 mrps-16 48.51(n)
    44.72(a)
      3565469  NM_001027036.2  NP_001022207.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes MRPS16(YPL013C)4 Mitochondrial ribosomal protein of the small subunit   --   16(529350-528985) 856094  NP_015312.1 


    ENSEMBL Gene Tree for MRPS16 (if available)
    TreeFam Gene Tree for MRPS16 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for MRPS16 gene

    Find genes that share paralogs with MRPS16           About GenesLikeMe


    5 Pseudogenes.org Pseudogenes for MRPS16
    PGOHUM00000258487 PGOHUM00000251248 PGOHUM00000247683 PGOHUM00000246577 PGOHUM00000249744


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for MRPS16 (see all 155)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 10 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1048941681,2
    Cpathogenic175383508(-) GACTGC/TGAAGG 2 R * stg10--------
    rs1397731131,2
    C--75381001(+) TAATCG/ATTCTC 1 -- ds50011Minor allele frequency- A:0.00EU 569
    rs1879284321,2
    --75381332(+) ATTATA/CTTTCT 1 -- ds50010--------
    rs10640201,2
    C,F,A,H--75381376(-) AAAATA/GGATGT 1 -- ds500121Minor allele frequency- G:0.36MN NS EA NA CSA WA 2523
    rs1928487081,2
    --75381424(+) AAATCA/GCACAC 1 -- ut310--------
    rs1848761741,2
    --75381680(+) AGAGAC/TGGGGT 1 -- ut310--------
    rs10548581,2
    A--75381770(-) ctcacA/Gcctgt 1 -- ut313Minor allele frequency- G:0.00MN NA 188
    rs1441930021,2
    --75381787(+) CCCCAA/GTGGTA 1 -- ut310--------
    rs20181981,2
    C,F,O,A,H--75381922(-) GTTCTA/TCTTTT 1 -- ut3111Minor allele frequency- T:0.11MN NS EA NA CSA WA EU 1552
    rs1884852571,2
    --75381969(+) ATAAAC/GATCCC 1 -- ut310--------

    HapMap Linkage Disequilibrium report for MRPS16 (75006510 - 75012451 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for MRPS16: --
    Human Gene Mutation Database (HGMD): MRPS16
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing MRPS16
    DNA2.0 Custom Variant and Variant Library Synthesis for MRPS16

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 609204   
    OMIM disorders: 610498  
    UniProtKB/Swiss-Prot: RT16_HUMAN, Q9Y3D3
  • Combined oxidative phosphorylation deficiency 2 (COXPD2) [MIM:610498]: A mitochondrial disease resulting
    in fatal neonatal metabolic acidosis with agenesis of the corpus callosum. Note=The disease is caused by
    mutations affecting the gene represented in this entry

  • 2 diseases for MRPS16:    
    About MalaCards
    combined oxidative phosphorylation deficiency 2    subcortical band heterotopia

    1 disease from the University of Copenhagen DISEASES database for MRPS16:
    Mitochondrial encephalomyopathy

    Find genes that share disorders with MRPS16           About GenesLikeMe

    Genetic Association Database (GAD): MRPS16
    Human Genome Epidemiology (HuGE) Navigator: MRPS16 (2 documents)

    Export disorders for MRPS16 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for MRPS16 gene, integrated from 10 sources (see all 26):
    (articles sorted by number of sources associating them with MRPS16)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics. (PubMed id 10810093)1, 2, 3 Lai C.-H.... Lin W.-C. (Genome Res. 2000)
    2. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (PLoS ONE 2010)
    3. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PubMed id 16385451)1, 4 Grupe A....Goate A. (Am. J. Hum. Genet. 2006)
    4. Defective mitochondrial translation caused by a ribosomal protein (MRPS16) mutation. (PubMed id 15505824)1, 2 Miller C.... Elpeleg O. (Ann. Neurol. 2004)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. The human mitochondrial ribosomal protein genes: mapping of 54 genes to the chromosomes and implications for human disorders. (PubMed id 11543634)1, 2 Kenmochi N.... Tanaka T. (Genomics 2001)
    7. Proteomic analysis of the mammalian mitochondrial ribosome. Identification of protein components in the 28S small subunit. (PubMed id 11402041)1, 2 Suzuki T....Watanabe K. (J. Biol. Chem. 2001)
    8. The small subunit of the mammalian mitochondrial ribosome: identification of the full complement of ribosomal proteins present. (PubMed id 11279123)1, 2 Koc E.C.... Spremulli L.L. (J. Biol. Chem. 2001)
    9. The effect of mutated mitochondrial ribosomal proteins S16 and S22 on the assembly of the small and large ribosomal subunits in human mitochondria. (PubMed id 18539099)1, 9 Emdadul Haque M....Saada A. (Mitochondrion 2008)
    10. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
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      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

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    Entrez Gene: 51021 HGNC: 14048 AceView: DNAJC9andMRPS16 Ensembl:ENSG00000182180 euGenes: HUgn51021
    ECgene: MRPS16 Kegg: 51021 H-InvDB: MRPS16

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for MRPS16 Pharmacogenomics, SNPs, Pathways
    GeneReviewshttp://www.ncbi.nlm.nih.gov/books/NBK1116/?term=MRPS16[genesymbol]

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for MRPS16 gene:
    Search GeneIP for patents involving MRPS16

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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