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Aliases for MRPL9 Gene

Aliases for MRPL9 Gene

  • Mitochondrial Ribosomal Protein L9 2 3 5
  • L9mt 3 4
  • MRP-L9 4

External Ids for MRPL9 Gene

Previous GeneCards Identifiers for MRPL9 Gene

  • GC01M149572
  • GC01M147514
  • GC01M148507
  • GC01M148948
  • GC01M148545
  • GC01M149998
  • GC01M151732
  • GC01M123108

Summaries for MRPL9 Gene

Entrez Gene Summary for MRPL9 Gene

  • This is a nuclear gene encoding a protein component of the 39S subunit of the mitochondrial ribosome. Alternative splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 8. [provided by RefSeq, Jul 2014]

GeneCards Summary for MRPL9 Gene

MRPL9 (Mitochondrial Ribosomal Protein L9) is a Protein Coding gene. Among its related pathways are Mitochondrial translation and Organelle biogenesis and maintenance. GO annotations related to this gene include poly(A) RNA binding and structural constituent of ribosome.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MRPL9 Gene

Genomics for MRPL9 Gene

Regulatory Elements for MRPL9 Gene

Enhancers for MRPL9 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around MRPL9 on UCSC Golden Path with GeneCards custom track

Promoters for MRPL9 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around MRPL9 on UCSC Golden Path with GeneCards custom track

Genomic Location for MRPL9 Gene

151,759,643 bp from pter
151,763,916 bp from pter
4,274 bases
Minus strand

Genomic View for MRPL9 Gene

Genes around MRPL9 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MRPL9 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MRPL9 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MRPL9 Gene

Proteins for MRPL9 Gene

  • Protein details for MRPL9 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    39S ribosomal protein L9, mitochondrial
    Protein Accession:
    Secondary Accessions:
    • B2RD99
    • Q5SZR2
    • Q9BSW8

    Protein attributes for MRPL9 Gene

    267 amino acids
    Molecular mass:
    30243 Da
    Quaternary structure:
    No Data Available

    Three dimensional structures from OCA and Proteopedia for MRPL9 Gene

neXtProt entry for MRPL9 Gene

Proteomics data for MRPL9 Gene at MOPED

Post-translational modifications for MRPL9 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for MRPL9 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for MRPL9 Gene

Domains & Families for MRPL9 Gene

Gene Families for MRPL9 Gene

Protein Domains for MRPL9 Gene

Suggested Antigen Peptide Sequences for MRPL9 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the ribosomal protein L9P family.
  • Belongs to the ribosomal protein L9P family.
genes like me logo Genes that share domains with MRPL9: view

Function for MRPL9 Gene

Phenotypes for MRPL9 Gene

GenomeRNAi human phenotypes for MRPL9:
genes like me logo Genes that share phenotypes with MRPL9: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for MRPL9 Gene

Localization for MRPL9 Gene

Subcellular locations from UniProtKB/Swiss-Prot for MRPL9 Gene


Subcellular locations from

Jensen Localization Image for MRPL9 Gene COMPARTMENTS Subcellular localization image for MRPL9 gene
Compartment Confidence
mitochondrion 5
nucleus 2

Gene Ontology (GO) - Cellular Components for MRPL9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005743 mitochondrial inner membrane TAS --
genes like me logo Genes that share ontologies with MRPL9: view

Pathways & Interactions for MRPL9 Gene

genes like me logo Genes that share pathways with MRPL9: view

Gene Ontology (GO) - Biological Process for MRPL9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006412 translation IEA,NAS 11543634
GO:0006996 organelle organization TAS --
GO:0032543 mitochondrial translation TAS --
genes like me logo Genes that share ontologies with MRPL9: view

No data available for SIGNOR curated interactions for MRPL9 Gene

Drugs & Compounds for MRPL9 Gene

No Compound Related Data Available

Transcripts for MRPL9 Gene

Unigene Clusters for MRPL9 Gene

Mitochondrial ribosomal protein L9:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for MRPL9 Gene

ExUns: 1a · 1b ^ 2a · 2b · 2c ^ 3a · 3b · 3c ^ 4a · 4b ^ 5 ^ 6a · 6b ^ 7 ^ 8 ^ 9a · 9b · 9c
SP1: - - - - -
SP2: - - - - - -
SP3: - - - - - - - -
SP4: - - - -
SP5: - - - - -
SP6: -
SP8: - - -
SP9: -

Relevant External Links for MRPL9 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MRPL9 Gene

mRNA expression in normal human tissues for MRPL9 Gene

Protein differential expression in normal tissues from HIPED for MRPL9 Gene

This gene is overexpressed in Peripheral blood mononuclear cells (11.4), Lung (8.6), Pancreas (7.7), and Adrenal (6.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for MRPL9 Gene

SOURCE GeneReport for Unigene cluster for MRPL9 Gene Hs.288936

genes like me logo Genes that share expression patterns with MRPL9: view

Protein tissue co-expression partners for MRPL9 Gene

- Elite partner

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for MRPL9 Gene

Orthologs for MRPL9 Gene

This gene was present in the common ancestor of animals.

Orthologs for MRPL9 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia MRPL9 35
  • 83.63 (n)
  • 81.25 (a)
MRPL9 36
  • 84 (a)
(Mus musculus)
Mammalia Mrpl9 35
  • 84.22 (n)
  • 83.59 (a)
Mrpl9 16
Mrpl9 36
  • 81 (a)
(Pan troglodytes)
Mammalia MRPL9 35
  • 99.63 (n)
  • 99.63 (a)
MRPL9 36
  • 100 (a)
(Rattus norvegicus)
Mammalia mrpl9 35
  • 83.8 (n)
  • 83.27 (a)
(Gallus gallus)
Aves MRPL9 35
  • 65.56 (n)
  • 69.17 (a)
MRPL9 36
  • 59 (a)
(Anolis carolinensis)
Reptilia MRPL9 36
  • 58 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.20048 35
African clawed frog
(Xenopus laevis)
Amphibia Xl.2544 35
(Danio rerio)
Actinopterygii mrpl9 35
  • 59.2 (n)
  • 58.71 (a)
wufa98b03 35
mrpl9 36
  • 49 (a)
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.8308 35
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP000950 35
  • 46.5 (n)
  • 36.5 (a)
fruit fly
(Drosophila melanogaster)
Insecta mRpL9 35
  • 45.17 (n)
  • 31.5 (a)
mRpL9 36
  • 26 (a)
Species with no ortholog for MRPL9:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MRPL9 Gene

Gene Tree for MRPL9 (if available)
Gene Tree for MRPL9 (if available)

Paralogs for MRPL9 Gene Pseudogenes for MRPL9 Gene

genes like me logo Genes that share paralogs with MRPL9: view

No data available for Paralogs for MRPL9 Gene

Variants for MRPL9 Gene

Sequence variations from dbSNP and Humsavar for MRPL9 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
VAR_028136 -
rs8480 - 151,760,859(-) ACCAG(A/C)AGAGC nc-transcript-variant, reference, missense
rs11454049 -- 151,760,577(+) GCTCA(-/AA)AAAAA intron-variant
rs10888433 -- 151,760,224(+) AGGTA(A/G)GTAAG intron-variant
rs10888434 -- 151,760,439(+) AGGCA(C/T)GGTGG intron-variant

Variation tolerance for MRPL9 Gene

Residual Variation Intolerance Score: 87.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 6.77; 78.95% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for MRPL9 Gene

Disorders for MRPL9 Gene

Relevant External Links for MRPL9

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MRPL9 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MRPL9 Gene

Publications for MRPL9 Gene

  1. Use of genome-wide expression data to mine the "Gray Zone" of GWA studies leads to novel candidate obesity genes. (PMID: 20532202) Naukkarinen J. … Peltonen L. (PLoS Genet. 2010) 3 48 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  3. Panorama of ancient metazoan macromolecular complexes. (PMID: 26344197) Wan C. … Emili A. (Nature 2015) 3
  4. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein M.Y. … Mann M. (Cell 2015) 3
  5. Proteomic analysis of the epidermal growth factor receptor (EGFR) interactome and post-translational modifications associated with receptor endocytosis in response to EGF and stress. (PMID: 24797263) Tong J. … Moran M.F. (Mol. Cell Proteomics 2014) 3

Products for MRPL9 Gene

Sources for MRPL9 Gene