Aliases for MRPL49 Gene
External Ids for MRPL49 Gene
Previous HGNC Symbols for MRPL49 Gene
Previous GeneCards Identifiers for MRPL49 Gene
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. Pseudogenes corresponding to this gene are found on chromosomes 5q and 8p. [provided by RefSeq, May 2011]
GeneCards Summary for MRPL49 Gene
MRPL49 (Mitochondrial Ribosomal Protein L49) is a Protein Coding gene. Diseases associated with MRPL49 include glossopharyngeal neuralgia. GO annotations related to this gene include structural constituent of ribosome.