Aliases for MRPL47 Gene
External Ids for MRPL47 Gene
Previous GeneCards Identifiers for MRPL47 Gene
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. This gene is immediately adjacent to the gene for BAF complex 53 kDa subunit protein a (BAF53a), in a tail-to-tail orientation. Two transcript variants encoding different protein isoforms have been identified. [provided by RefSeq, Jul 2008]
GeneCards Summary for MRPL47 Gene
MRPL47 (Mitochondrial Ribosomal Protein L47) is a Protein Coding gene. Diseases associated with MRPL47 include nasopharyngeal carcinoma. GO annotations related to this gene include structural constituent of ribosome.