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MRPL44 Gene

protein-coding   GIFtS: 53
GCID: GC02P224822

Mitochondrial Ribosomal Protein L44

  See MRPL44-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Mitochondrial Ribosomal Protein L441 2     39S Ribosomal Protein L44, Mitochondrial2
MRP-L442 3     L44MT2
COXPD162 5     EC 3.1.26.-3
39S Ribosomal Protein L441     L44mt3
mitochondrial1     EC 3.1.268

External Ids:    HGNC: 166501   Entrez Gene: 650802   Ensembl: ENSG000001359007   OMIM: 6118495   UniProtKB: Q9H9J23   

Export aliases for MRPL44 gene to outside databases

Previous GC identifers: GC02P222844 GC02P223543 GC02P224786 GC02P225024 GC02P224647 GC02P224530 GC02P216673


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for MRPL44 Gene:
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the
mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit.
They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is
reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain
a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and
sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a
39S subunit protein. (provided by RefSeq, Jul 2008)

GeneCards Summary for MRPL44 Gene:
MRPL44 (mitochondrial ribosomal protein L44) is a protein-coding gene. Diseases associated with MRPL44 include combined oxidative phosphorylation deficiency 16. GO annotations related to this gene include RNA binding and ribonuclease III activity.

UniProtKB/Swiss-Prot: RM44_HUMAN, Q9H9J2
Function: Component of the 39S subunit of mitochondrial ribosome. May have a function in the assembly/stability of
nascent mitochondrial polypeptides exiting the ribosome




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000002.11  NC_018913.2  NT_005403.18  
Regulatory elements:
   Regulatory transcription factor binding sites in the MRPL44 gene promoter:
         c-Fos   AP-1   CUTL1   HNF-4alpha1   GATA-1   NRF-2   c-Myb   ZID   c-Jun   Ik-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMRPL44 promoter sequence
   Search Chromatin IP Primers for MRPL44

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MRPL44


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q36.1   Ensembl cytogenetic band:  2q36.1   HGNC cytogenetic band: 2p24.3-p24.1

MRPL44 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MRPL44 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02P224822:  view genomic region     (about GC identifiers)

Start:
224,822,121 bp from pter      End:
224,832,431 bp from pter
Size:
10,311 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: RM44_HUMAN, Q9H9J2 (See protein sequence)
Recommended Name: 39S ribosomal protein L44, mitochondrial precursor  
Size: 332 amino acids; 37535 Da
Secondary accessions: Q53S16 Q6IA62 Q9H821

Explore the universe of human proteins at neXtProt for MRPL44: NX_Q9H9J2

Explore proteomics data for MRPL44 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus
  • 2 DME Specific Peptides for MRPL44 (Q9H9J2)
     NSCYIKSEEAKRQ  LFIRDFLITQMTGKELFE 


    See MRPL44 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_075066.1  
    ENSEMBL proteins: 
     ENSP00000258383  

    MRPL44 Human Recombinant Protein Products:

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    Sino Biological Cell Lysate for MRPL44
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    Cloud-Clone Corp. Proteins for MRPL44

     
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    Cloud-Clone Corp. ELISAs for MRPL44
    Cloud-Clone Corp. CLIAs for MRPL44
    Search eBioscience for ELISAs for MRPL44 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    MRPL: Mitochondrial ribosomal proteins / large subunits

    2 InterPro protein domains:
     IPR014720 dsRNA-bd_dom
     IPR000999 RNase_III_dom

    Graphical View of Domain Structure for InterPro Entry Q9H9J2

    ProtoNet protein and cluster: Q9H9J2

    1 Blocks protein domain: IPB001159 Double-stranded RNA binding (DsRBD) domain

    UniProtKB/Swiss-Prot: RM44_HUMAN, Q9H9J2
    Similarity: Contains 1 DRBM (double-stranded RNA-binding) domain
    Similarity: Contains 1 RNase III domain


    Find genes that share domains with MRPL44           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: RM44_HUMAN, Q9H9J2
    Function: Component of the 39S subunit of mitochondrial ribosome. May have a function in the assembly/stability of
    nascent mitochondrial polypeptides exiting the ribosome

         Enzyme Numbers (IUBMB): EC 3.1.26.-1 EC 3.1.262

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
    GO:0003723RNA binding ----
    GO:0004525ribonuclease III activity IEA--
    GO:0044822poly(A) RNA binding IDA--
         
    Find genes that share ontologies with MRPL44           About GenesLikeMe


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for MRPL44
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    miRNA
    Products:
        
    miRTarBase miRNAs that target MRPL44:
    hsa-mir-101-3p (MIRT027245), hsa-mir-128-3p (MIRT022007)

    Block miRNA regulation of human, mouse, rat MRPL44 using miScript Target Protectors
    5 qRT-PCR Assays for microRNAs that regulate MRPL44:
    hsa-miR-3163 hsa-miR-3613-3p hsa-miR-3120-3p hsa-miR-545 hsa-miR-590-3p
    SwitchGear 3'UTR luciferase reporter plasmidMRPL44 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat MRPL44

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MRPL44


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    RM44_HUMAN, Q9H9J2: Mitochondrion
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    mitochondrion5
    nucleus1
    plasma membrane1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005575cellular_component ND--
    GO:0005739mitochondrion IEA--
    GO:0005840ribosome IEA--

    Find genes that share ontologies with MRPL44           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for MRPL44
    Interactions:

        Search GeneGlobe Interaction Network for MRPL44

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for MRPL44 (Q9H9J22, 3 ENSP000002583834) via UniProtKB, MINT, STRING, and/or I2D (see all 293)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    IMMTQ168912, 3, ENSP000003872624MINT-65524 MINT-8263324 I2D: score=5 STRING: ENSP00000387262
    SETDB1Q150472, 3MINT-65523 MINT-8263390 I2D: score=5 
    VIMP086702, 3MINT-65525 MINT-8263423 I2D: score=5 
    USP22Q9UPT92, 3, ENSP000002614974MINT-8263412 I2D: score=2 STRING: ENSP00000261497
    CEP70Q8NHQ12, 3MINT-8263313 I2D: score=2 
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006396RNA processing IEA--
    GO:0008150biological_process ND--
    GO:0070125mitochondrial translational elongation IMP--

    Find genes that share ontologies with MRPL44           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for MRPL44 (RM44)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for MRPL44 gene: 
    NM_022915.3  

    Unigene Cluster for MRPL44:

    Mitochondrial ribosomal protein L44
    Hs.203559  [show with all ESTs]
    Unigene Representative Sequence: NM_022915
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000258383(uc002vnr.4)
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat MRPL44 using miScript Target Protectors
    5 qRT-PCR Assays for microRNAs that regulate MRPL44:
    hsa-miR-3163 hsa-miR-3613-3p hsa-miR-3120-3p hsa-miR-545 hsa-miR-590-3p
    SwitchGear 3'UTR luciferase reporter plasmidMRPL44 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for MRPL44
    Predesigned siRNA for gene silencing in human, mouse, rat MRPL44
    Clone
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    OriGene ORF clones in mouse, rat for MRPL44
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    GenScript: all cDNA clones in your preferred vector: MRPL44 (NM_022915)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MRPL44
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MRPL44
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for MRPL44
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat MRPL44
      QuantiTect SYBR Green Assays in human, mouse, rat MRPL44
      QuantiFast Probe-based Assays in human, mouse, rat MRPL44

    Additional mRNA sequence: 

    AK022763.1 AK024052.1 BC012058.1 CR457293.1 

    10 DOTS entries:

    DT.100793281  DT.452211  DT.100646434  DT.100793282  DT.95166179  DT.100793283  DT.120940347  DT.100793285 
    DT.40242382  DT.95126723 

    Selected AceView cDNA sequences (see all 178):

    BQ961422 CR598480 AL701506 CR613852 BX421883 BG031637 CB118273 BM547681 
    AU280614 BC012058 BE264998 AA136405 BM477275 CR626643 CR619403 BM924516 
    CR457293 AW190925 AI936229 AW249380 N31234 BG036197 BE467972 BX418552 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    MRPL44 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GATGCAGCAG
    MRPL44 Expression
    About this image


    MRPL44 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Eye (Sensory Organs)
             Retina
     
     Thyroid (Endocrine System)
    MRPL44 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    MRPL44 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.203559
        Custom PCR Arrays for MRPL44
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MRPL44

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for MRPL44 gene from Selected species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Mrpl441 , 5 mitochondrial ribosomal protein L441, 5 81.93(n)1
    85.84(a)1
      1 (40.96 cM)5
    691631  NM_001081210.11  NP_001074679.11 
     797760185 
    chicken
    (Gallus gallus)
    Aves MRPL441 mitochondrial ribosomal protein L44 65.02(n)
    67.18(a)
      424795  NM_001277414.1  NP_001264343.1 
    lizard
    (Anolis carolinensis)
    Reptilia MRPL446
    mitochondrial ribosomal protein L44
    68(a)
    1 ↔ 1
    3(23419069-23426739)
    African clawed frog
    (Xenopus laevis)
    Amphibia MGC643462 hypothetical protein MGC64346 71.89(n)    BC054195.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.24832 Transcribed sequence with weak similarity to protein more 74.23(n)    CK236072.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta mRpL441 , 3 structural constituent of ribosome3
    mitochondrial ribosomal protein L441
    35(a)3
    46.44(n)1
    36.64(a)1
      83A43
    406561  NM_141284.31  NP_649541.11 


    ENSEMBL Gene Tree for MRPL44 (if available)
    TreeFam Gene Tree for MRPL44 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for MRPL44 (see all 287)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0705684
    Combined oxidative phosphorylation deficiency 16 (COXPD16)4--see VAR_0705682 L R mis40--------
    rs38064901,2
    C,F,A,H--224197941(-) GATGGA/GTAACA 1 -- us2k119Minor allele frequency- G:0.18EA NA NS WA 1420
    rs38064891,2
    C,F,A,H--224197958(-) AATACG/AGGGCA 1 -- us2k114Minor allele frequency- A:0.28NA NS EA WA 924
    rs102098831,2
    C,F,H--224198052(+) AAAGTG/AAACCC 1 -- us2k1 tfbs313Minor allele frequency- A:0.10NS EA NA WA 1082
    rs1859011781,2
    --224198133(+) AACTCA/GAAAGT 1 -- us2k10--------
    rs1500002911,2
    --224198303(+) ATAAAC/TAGACA 1 -- us2k10--------
    rs10366001,2
    C,F,O,A,H--224198420(-) AACAAC/TGAGAG 1 -- us2k122Minor allele frequency- T:0.31NS EA NA WA CSA 2834
    rs1911482571,2
    C--224198469(+) TTAACG/TTAACA 1 -- us2k10--------
    rs168653501,2
    C,F,H--224198496(+) GGCTTA/GGATTA 1 -- us2k18Minor allele frequency- G:0.07NA NS EA WA 680
    rs779435291,2
    F--224198714(+) TTTTGC/TTCTCT 1 -- us2k12Minor allele frequency- T:0.04CSA WA 120

    HapMap Linkage Disequilibrium report for MRPL44 (224822121 - 224832431 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for MRPL44:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv511173CNV Loss21212237

    Human Gene Mutation Database (HGMD): MRPL44
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing MRPL44
    DNA2.0 Custom Variant and Variant Library Synthesis for MRPL44

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 611849   
    OMIM disorders: 615395  
    UniProtKB/Swiss-Prot: RM44_HUMAN, Q9H9J2
  • Combined oxidative phosphorylation deficiency 16 (COXPD16) [MIM:615395]: An autosomal recessive,
    mitochondrial disorder characterized by hypertrophic cardiomyopathy, liver steatosis, and decreased levels of
    mitochondrial complexes I and IV in heart and skeletal muscle. Note=The disease is caused by mutations affecting
    the gene represented in this entry

  • 1 disease for MRPL44:    
    About MalaCards
    combined oxidative phosphorylation deficiency 16


    Find genes that share disorders with MRPL44           About GenesLikeMe

    Genetic Association Database (GAD): MRPL44
    Human Genome Epidemiology (HuGE) Navigator: MRPL44 (1 document)

    Export disorders for MRPL44 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for MRPL44 gene, integrated from 10 sources (see all 25):
    (articles sorted by number of sources associating them with MRPL44)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Whole-exome sequencing identifies a mutation in the mitochondrial ribosome protein MRPL44 to underlie mitochondrial infantile cardiomyopathy. (PubMed id 23315540)1, 2 Carroll C.J.... Suomalainen A. (J. Med. Genet. 2013)
    2. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (PLoS ONE 2010)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. The large subunit of the mammalian mitochondrial ribosome. Analysis of the complement of ribosomal proteins present. (PubMed id 11551941)1, 2 Koc E.C.... Spremulli L.L. (J. Biol. Chem. 2001)
    6. Quantitative study of the interactome of PKCIP involved in the EGF-induced tumor cell chemotaxis. (PubMed id 23402259)1 Chen R....Zhang N. (J. Proteome Res. 2013)
    7. p32/gC1qR is indispensable for fetal development and mitochondrial translation: importance of its RNA-binding ability. (PubMed id 22904065)1 Yagi M....Kang D. (Nucleic Acids Res. 2012)
    8. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    9. Biochemical and phosphoproteomic analysis of the helix-loop-helix protein E47. (PubMed id 22354994)1 Teachenor R....Murre C. (Mol. Cell. Biol. 2012)
    10. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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      Query String
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 65080 HGNC: 16650 AceView: MRPL44 Ensembl:ENSG00000135900 euGenes: HUgn65080
    ECgene: MRPL44 H-InvDB: MRPL44

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for MRPL44 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for MRPL44 gene:
    Search GeneIP for patents involving MRPL44

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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