MRPL43 Gene
protein-coding GIFtS: 46
GCID: GC10M102737
|
|
mitochondrial ribosomal protein L43
| |
Aliases
for MRPL43 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Mitochondrial Ribosomal Protein L431 2 | | BMRP36a1 | | Mitochondrial Ribosomal Protein BMRP36a2 3 | | L43mt2 3 | | MRP-L432 3 | | 39S Ribosomal Protein L43, Mitochondrial2 |
Export aliases for MRPL43 gene to outside databasesPrevious GC identifers: GC10M101639 GC10M101971 GC10M102860 GC10M102402 GC10M102727 GC10M096366 |
Summaries
for MRPL43 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for MRPL43:
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within themitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. Theyhave an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed.Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA.Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes inbiochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein.This gene and the gene for a semaphorin class 4 protein (SEMA4G) overlap at map location 10q24.31 and are transcribedin opposite directions. Sequence analysis identified multiple transcript variants encoding at least four differentprotein isoforms. (provided by RefSeq, Jul 2008)
|
Genomic Views
for MRPL43 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000010.10 NC_018921.1 NT_030059.13
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the MRPL43 gene promoter:
COUP-TF1 Sp1 Pax-5 COUP HNF-4alpha2 HNF-4alpha1 COUP-TF NF-kappaB1
Other transcription factors
Search SABiosciences Chromatin IP Primers for MRPL43
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MRPL43 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 10q24.31 Ensembl cytogenetic band: 10q24.31 HGNC cytogenetic band: 10q24.31MRPL43 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 10 GeneLoc Exon Structure GeneLoc location for GC10M102737: view genomic region
(about GC identifiers)
Start:
|
102,729,215 bp from pter |
End:
|
102,747,272 bp from pter |
Size:
|
18,058 bases |
Orientation:
|
minus strand |
|
Proteins
for MRPL43 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: RM43_HUMAN, Q8N983 (See
protein sequence)Recommended Name: 39S ribosomal protein L43, mitochondrial precursor Size: 215 amino acids; 23431 Da
Subcellular location: Mitochondrion
Secondary accessions: B1AL07 B1AL09 B1AL10 D3DR71 Q5JW06 Q7Z719 Q7Z7H6 Q86XN1 Q9BYC7Alternative splicing: 4 isoforms: Q8N983-1 Q8N983-2 Q8N983-3 Q8N983-4 (Ref.1 (BAB40861) sequence differs from that shown due to frameshifts in positions 131 and 210)Explore the universe of human proteins at neXtProt for MRPL43: NX_Q8N983
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8N983
MRPL43 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (4 alternative transcripts):
NP_115488.2 NP_789762.1 NP_789763.1 NP_789764.1
ENSEMBL proteins: ENSP00000430369 ENSP00000315364 ENSP00000359261 ENSP00000359262 ENSP00000408806 ENSP00000299179 ENSP00000359256 ENSP00000315948 ENSP00000359254 ENSP00000339844
Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
MRPL43 for ontologies About GeneDecksing
MRPL43 Antibody Products:
Assay Products for MRPL43: |
Protein
Domains /
Families
for MRPL43 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
MRPL43 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q8N983ProtoNet protein and cluster: Q8N983 1 Blocks protein family: IPB007741 Mitochondrial ribosome
UniProtKB/Swiss-Prot: RM43_HUMAN, Q8N983Similarity: Belongs to the ribosomal protein S25/L51 family |
Function
for MRPL43 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MRPL43 (see all 6)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MRPL43 (see all 4)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 4): MRPL43 (NM_176793) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MRPL43 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MRPL43 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MRPL43 |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003735 | structural constituent of ribosome |
NAS | 11543634 |
MRPL43 for ontologies About GeneDecksing
|
Pathways & Interactions
for MRPL43 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MRPL43
STRING Interaction
Network Preview (showing 5 interactants - click image to see 6)
5/236 Interacting proteins for MRPL43 (Q8N9832, 3 ENSP000003398444) via UniProtKB, MINT, STRING, and/or I2D (see all 236)About this table
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table
MRPL43 for ontologies About GeneDecksing
|
Drugs & Compounds
for MRPL43 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for MRPL43
Search CenterWatch for drugs/clinical trials and news about MRPL43 / RM43
|
Transcripts
for MRPL43 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for MRPL43 gene (4 alternative transcripts): NM_032112.2 NM_176792.2 NM_176793.1 NM_176794.1 Unigene Cluster for MRPL43: Mitochondrial ribosomal protein L43 Hs.744144 [show with all ESTs]Unigene Representative Sequence: NM_17679214 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000523148 ENST00000318325(uc001kry.1 uc010qpu.1) ENST00000370241
ENST00000370242 ENST00000476012(uc001krz.1) ENST00000448244 ENST00000299179
ENST00000370236 ENST00000493646 ENST00000318364(uc001ksc.3 uc001ksd.1)
ENST00000477279 ENST00000370234 ENST00000487059 ENST00000342071(uc001ksa.1 uc001ksb.1)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MRPL43 (see all 6)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MRPL43 (see all 4)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
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Synthesis Service for MRPL43 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MRPL43 |
Additional cDNA sequence: AB049656.1 AF086122.1 AK095556.1 AK291069.1 AK300237.1 BC015905.1 BC031287.1 BC041165.1 BC052639.1 BC053373.1 23 DOTS entries: DT.100826449 DT.455116 DT.97846893 DT.95158436 DT.97846895 DT.87016066 DT.447369 DT.92454514 DT.121293602 DT.95158431 DT.100826456 DT.100712338 DT.102843359 DT.121293595 DT.95212746 DT.92454517 DT.95158442 DT.95258822 DT.100712337 DT.100826453 DT.100826455 DT.99937075 DT.95098189 24/388 AceView cDNA sequences (see all 388): BC052639 AI828278 CA844070 BM707761 BU580612 AI378403 NM_176794 BX341409 AI184400 T34337 BU689273 AA693829 CA415379 BU507377 AA627500 BC041165 AA987570 CA942279 F27590 BQ286786 AI014795 CR593768 AI867984 CR616314
GeneLoc Exon Structure
5/6 Alternative Splicing Database (ASD) splice patterns (SP) for MRPL43 (see all 6) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2a | · | 2b | ^ | 3a | · | 3b | · | 3c | · | 3d | ^ | 4a | · | 4b | · | 4c | · | 4d |
|---|
|
| SP1: | | | | | | | | | - | | | | | | | | - | | - | | | | | | | | | | |
| SP2: | | | | | | | | | - | | | | | | - | | - | | - | | | | | | | | | | |
| SP3: | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | - | | - | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for MRPL43
|
Expression
for MRPL43 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| MRPL43 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CTGTCCAGGG
About this image
See MRPL43 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for MRPL43
SOURCE GeneReport for Unigene cluster: Hs.744144
UniProtKB/Swiss-Prot: RM43_HUMAN, Q8N983Tissue specificity: High relative levels in skeletal muscle and testis. Lower levels of expression in the heart, brain,placenta, lung, liver, kidney, pancreas, spleen, thymus, prostate, ovary, small intestine, colon and leukocytes.Expression is coregulated with PEO1
SABiosciences Custom PCR Arrays for MRPL43
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MRPL43
Browse OriGene validated miRNA SYBR primer pairs
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Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MRPL43 |
Orthologs
for MRPL43 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for MRPL43 gene from 8/25 species (see all 25) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Mrpl431 , 5 |
mitochondrial ribosomal protein L431, 5 |
82.39(n)1
81.13(a)1 |
|
19 (38.19 cM)5
940671 NM_053164.31 NP_444394.11
450050145 |
lizard
(Anolis carolinensis) |
Reptilia |
MRPL436 |
-- |
61(a) |
1 ↔ 1 |
3(39294351-39298856) |
African clawed frog
(Xenopus laevis) |
Amphibia |
MGC540022 |
similar to mitochondrial ribosomal protein L43 |
73.99(n) |
|
BC044005.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
Dr.180762 |
Transcribed sequence with weak similarity to protein more |
79.01(n) |
|
BQ614690.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
mRpL431 |
mitochondrial ribosomal protein L43 |
51.85(n)
46.83(a) |
|
37750 NM_079104.2 NP_523828.1 |
worm
(Caenorhabditis elegans) |
Secernentea |
mrpl-341 |
Protein MRPL-34 |
39.19(n)
35.88(a) |
|
182876 NM_060285.1 NP_492686.1 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
AT3G596506 |
mitochondrial ribosomal protein L51/S25/CI-B8 fami... |
21(a) |
1 ↔ 1 |
3(22033129-22034157) |
rice
(Oryza sativa) |
Liliopsida |
-- |
ribosomal protein L51, putative, expressed |
27(a) |
1 ↔ 1 |
3(5612250-5614478) |
ENSEMBL Gene Tree for MRPL43 (if available)
TreeFam Gene Tree for MRPL43 (if available) |
Paralogs
for MRPL43 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for MRPL43 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for MRPL43
2 CNVs: 48397 4711 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MRPL43 |
|
Disorders
/ Diseases
for MRPL43 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
MRPL43 for disorders About GeneDecksing
OMIM gene information: 611848
OMIM disorders: --
5  diseases for MRPL43: About MalaCardschronic progressive external ophthalmoplegia ophthalmoplegia paraplegia alzheimer's disease
prostatitis
Human Genome Epidemiology (HuGE) Navigator: MRPL43 (2 documents)
Export disorders for MRPL43 gene to outside databases
|
Publications
for MRPL43 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for MRPL43 gene, integrated from 9 sources (see all 18):
(articles sorted by number of sources associating them with MRPL43) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Twinkle helicase is essential for mtDNA maintenance and regulates mtDNA copy number. (PubMed id 15509589)1, 2 Tyynismaa H.... Suomalainen A. (2004)
- Structural compensation for the deficit of rRNA with proteins in the mammalian mitochondrial ribosome. Systematic analysis of protein components of the large ribosomal subunit from mammalian mitochondria. (PubMed id 11279069)1, 2 Suzuki T....Watanabe K. (2001)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
- A functional peptidyl-tRNA hydrolase, ICT1, has been recruited into the human mitochondrial ribosome. (PubMed id 20186120)1 Richter R....Chrzanowska-Lightowlers Z.M. (2010)
- Systematic analysis of human protein complexes identi fies chromosome segregation proteins. (PubMed id 20360068)1 Hutchins J.R....Peters J.M. (2010)
- Genetic variants in nuclear-encoded mitochondrial gen es influence AIDS progression. (PubMed id 20877624)1 Hendrickson S.L....O'Brien S.J. (2010)
|
External Searches for MRPL43 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing MRPL43 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing MRPL43 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing MRPL43 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for MRPL43 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for MRPL43 gene:
Search GeneIP for patents involving MRPL43
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for MRPL43 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
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| |
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| |  |  |  |  | | | | |
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 |
 | | | MRPL43 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MRPL43 |
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