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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

MRPL41 Gene

protein-coding   GIFtS: 46
GCID: GC09P140445

mitochondrial ribosomal protein L41
 Explore 2 diseases affiliated with
MRPL41 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for MRPL41    

Aliases
for MRPL41 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Mitochondrial Ribosomal Protein L411 2     39S Ribosomal Protein L27 Homolog2 3
MRPL271 2 3 5     L41mt2 3
BMRP1 2 3     MRP-L412 3
RPML271 2 3     MRP-L27 Homolog2 3
MRP-L271 2     PIG31
Bcl-2-Interacting Mitochondrial Ribosomal Protein L412 3     39S Ribosomal Protein L41, Mitochondrial2
Cell Proliferation-Inducing Gene 3 Protein2 3     Proliferation-Inducing Gene 32

External Ids:    HGNC: 144921   Entrez Gene: 649752   Ensembl: ENSG000001821547   OMIM: 6118465   UniProtKB: Q8IXM33   

Export aliases for MRPL41 gene to outside databases

Previous GC identifers: GC09P131796 GC09M132098 GC09P133748 GC09P135664 GC09P137722 GC09P139565 GC09P109910


Summaries
for MRPL41 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for MRPL41:
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the
mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They
have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed.
Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA.
Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in
biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein
that belongs to the YmL27 ribosomal protein family. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: RM41_HUMAN, Q8IXM3
Function: Component of the mitochondrial ribosome large subunit. Also involved in apoptosis and cell cycle. Enhances
p53/TP53 stability, thereby contributing to p53/TP53-induced apoptosis in response to growth-inhibitory condition.
Enhances p53/TP53 translocation to the mitochondria. Has the ability to arrest the cell cycle at the G1 phase,
possibly by stabilizing the CDKN1A and CDKN1B (p27Kip1) proteins

Gene Wiki entry for MRPL41 (Mitochondrial ribosomal protein L41)


Genomic Views
for MRPL41 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000009.11  NC_018920.1  NT_024000.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the MRPL41 gene promoter:
         E2F-3a   E2F-4   E2F-5   Tal-1   Nkx2-5   E2F-2   E47   NRF-2   E2F-1   E2F   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: MRPL41 promoter sequence
   Search SABiosciences Chromatin IP Primers for MRPL41

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MRPL41


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9q34.3   Ensembl cytogenetic band:  9q34.3   HGNC cytogenetic band: 9q34.3

MRPL41 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MRPL41 gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09P140445:  view genomic region     (about GC identifiers)

Start:
 140,445,651 bp from pter      End:
 140,447,007 bp from pter
Size:
 1,357 bases      Orientation:
 plus strand

Proteins
for MRPL41 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: RM41_HUMAN, Q8IXM3 (See protein sequence)
Recommended Name: 39S ribosomal protein L41, mitochondrial precursor  
Size: 137 amino acids; 15383 Da
Subunit: Component of the mitochondrial ribosome large subunit (39S) which comprises a 16S rRNA and about 50 distinct
proteins. Interacts with BCL2
Subcellular location: Mitochondrion
Secondary accessions: Q96Q49

Explore the universe of human proteins at neXtProt for MRPL41: NX_Q8IXM3

MRPL41 Protein expression data from MOPED and PaxDb:    About this image 

Estimated protein expression log10 (pmol).

REFSEQ proteins: NP_115866.1  
ENSEMBL proteins: 
 ENSP00000360498  

Human Recombinant Protein Products: 
Browse Purified and Recombinant Proteins at EMD Millipore
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Browse recombinant and purified proteins available from Enzo Life Sciences
OriGene Purified Protein: MRPL41
OriGene Protein Over-expression Lysate: MRPL41
OriGene Custom Protein Services for MRPL41 
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Novus Biologicals MRPL41 Protein
Novus Biologicals MRPL41 Lysate
Browse Sino Biological Recombinant Proteins
Browse ProSpec Recombinant Proteins
Uscn Proteins for MRPL41

Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005739mitochondrion IDA--
GO:0005762mitochondrial large ribosomal subunit IDA16024796
GO:0030529ribonucleoprotein complex IDA16024796


MRPL41 for ontologies           About GeneDecksing



MRPL41 Antibody Products: 
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Uscn Antibodies for MRPL41
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Assay Products for MRPL41: 
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GenScript Custom Assay Services for MRPL41
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Uscn ELISAs and CLIAs for MRPL41

Protein Domains /
Families
for MRPL41 gene

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section
MRPL41 for domains           About GeneDecksing

1 InterPro domain/family:
 IPR019189 Ribosomal_L27/L41_mit

Graphical View of Domain Structure for InterPro Entry Q8IXM3

ProtoNet protein and cluster: Q8IXM3

UniProtKB/Swiss-Prot: RM41_HUMAN, Q8IXM3
Similarity: Belongs to the ribosomal protein L41 family


Function
for MRPL41 gene

(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section
Function Summary:

     UniProtKB/Swiss-Prot: RM41_HUMAN, Q8IXM3
Function: Component of the mitochondrial ribosome large subunit. Also involved in apoptosis and cell cycle. Enhances
p53/TP53 stability, thereby contributing to p53/TP53-induced apoptosis in response to growth-inhibitory condition.
Enhances p53/TP53 translocation to the mitochondria. Has the ability to arrest the cell cycle at the G1 phase,
possibly by stabilizing the CDKN1A and CDKN1B (p27Kip1) proteins

miRNA
Products:    		 OriGene 3'-UTR Clone: MRPL41
Browse MicroRNA Expression Plasmids
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MRPL41
Search QIAGEN for miScript miRNA Assays for microRNAs that regulate MRPL41
SwitchGear 3'UTR luciferase reporter plasmid: MRPL41 3' UTR sequence
Inhib. RNA
Products:    		Browse for Gene Knock-down Tools from EMD Millipore
OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MRPL41 (see all 7)
OriGene shRNA RFP: MRPL41
OriGene siRNA: MRPL41
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MRPL41

Gene Editing
Products:		DNA2.0 Custom Protein Engineering Service for MRPL41

Clone
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OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MRPL41
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GenScript: all cDNA clones in your preferred vector: MRPL41 (NM_032477)
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DNA2.0 Custom Codon Optimized Gene Synthesis Service for MRPL41
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MRPL41 

Cell Line
Products:     		GenScript Custom overexpressing Cell Line Services for MRPL41
Search LifeMap BioReagents cell lines for MRPL41

In Situ Assay
Products:   
 		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MRPL41

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0003735structural constituent of ribosome IDA16024796


MRPL41 for ontologies           About GeneDecksing



Pathways & Interactions
for MRPL41 gene

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section



Interactions:

    Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MRPL41

STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

5/236 Interacting proteins for MRPL41 (Q8IXM32, 3 ENSP000003604984) via UniProtKB, MINT, STRING, and/or I2D (see all 236)
InteractantInteraction Details
GeneCardExternal ID(s)
TRIM63Q969Q12, 3, ENSP000003633904MINT-6492226 MINT-6503690 I2D: score=1 STRING: ENSP00000363390
SMURF2Q9HAU42, 3, ENSP000002624354MINT-6504060 I2D: score=1 STRING: ENSP00000262435
ICT1Q141972, 3, ENSP000003015854MINT-8079030 I2D: score=1 STRING: ENSP00000301585
C20orf24Q9BUV83, ENSP000003412134I2D: score=1 STRING: ENSP00000341213
SLX4Q8IY923, ENSP000002940084I2D: score=1 STRING: ENSP00000294008
About this table

Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0006412translation IDA16024796
GO:0006915apoptotic process IEA--
GO:0007049cell cycle IEA--


MRPL41 for ontologies           About GeneDecksing



Drugs & Compounds
for MRPL41 gene

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section
Browse Small Molecules at EMD Millipore
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for MRPL41
Search CenterWatch for drugs/clinical trials and news about MRPL41 / RM41 

Transcripts
for MRPL41 gene

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section
REFSEQ mRNAs for MRPL41 gene: 
NM_032477.2  

Unigene Cluster for MRPL41:

Mitochondrial ribosomal protein L41
Hs.44017  [show with all ESTs]
Unigene Representative Sequence: BQ955623
1 Ensembl transcript including schematic representation, and UCSC links where relevant:
ENST00000371443(uc004cnh.4)

miRNA
Products:     		 OriGene 3'-UTR Clone: MRPL41
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QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MRPL41
Search QIAGEN for miScript miRNA Assays for microRNAs that regulate MRPL41
SwitchGear 3'UTR luciferase reporter plasmid: MRPL41 3' UTR sequence
Inhib. RNA
Products:     		Browse for Gene Knock-down Tools from EMD Millipore
OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MRPL41 (see all 7)
OriGene shRNA RFP: MRPL41
OriGene siRNA: MRPL41
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MRPL41
Clone
Products:     		 OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MRPL41 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MRPL41
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
GenScript: all cDNA clones in your preferred vector: MRPL41 (NM_032477)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for MRPL41
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MRPL41 
Primer
Products:    		 OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MRPL41
Browse OriGene validated miRNA SYBR primer pairs
SABiosciences RT2 qPCR Primer Assay in human, mouse, rat MRPL41
  QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MRPL41
  QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MRPL41

Additional cDNA sequence: 

AY232291.1 BC040035.1 

10 DOTS entries:

DT.87001237  DT.450215  DT.87077214  DT.91779100  DT.98131734  DT.121187687  DT.100883254  DT.100883250 
DT.100883257  DT.447660 

24/443 AceView cDNA sequences (see all 443):

AA922694 BF437902 AI568381 AI300803 AI298799 AI681348 BE882251 AI375476 
BE676728 BE675258 AI475844 BM512028 AJ346111 AA969171 AI400599 BU734356 
BM704939 AA907011 AI083690 AI290984 AI435280 BF590212 BM707716 AI281964 

GeneLoc Exon Structure


Expression
for MRPL41 gene

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

MRPL41 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GGCGTCCTGG

Microarray
RNAseq (Illumina Body Map)
(100×FPKM)½
SAGE (Serial Analysis of Gene Expression)
About this image

MRPL41 expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
Stem Cell Differentiation: 1 LifeMap Cell 
NameCategory
Definitive endoderm-like cells (A scalable, suspensi...)
Expression: Positive    Negative     Selective marker
Experimental details: Curated     Microarrays     In-situ hybridization

See MRPL41 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for MRPL41

SOURCE GeneReport for Unigene cluster: Hs.44017

UniProtKB/Swiss-Prot: RM41_HUMAN, Q8IXM3
Tissue specificity: Present in kidney, liver, thymus and testis, and at lower level in brain and spleen (at protein
level)

    SABiosciences Custom PCR Arrays for MRPL41
Primer
Products:		 OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MRPL41
Browse OriGene validated miRNA SYBR primer pairs
SABiosciences RT2 qPCR Primer Assay in human, mouse, rat MRPL41
QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MRPL41
QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MRPL41
In Situ
Assay Products: 
 		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MRPL41

Orthologs
for MRPL41 gene

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section
This gene was present in the common ancestor of eukaryotes.

Orthologs for MRPL41 gene from 7/18 species (see all 18)    About this table
Organism Taxonomic
classification		 Gene Description Human
Similarity		 Orthology
Type		 Details
mouse
(Mus musculus)		 Mammalia Mrpl411 , 5 mitochondrial ribosomal protein L411, 5 73.83(n)1
77.04(a)1		   2 (16.88 cM)5
1077331  NM_001031808.21  NP_001026978.21 
 249741175 
chicken
(Gallus gallus)		 Aves MRPL411 mitochondrial ribosomal protein L41 76.54(n)
73.33(a)		   417261  XM_415536.2  XP_415536.1 
African clawed frog
(Xenopus laevis)		 Amphibia Xl.68092 Xenopus laevis transcribed sequences 74.28(n)    48030705 
zebrafish
(Danio rerio)		 Actinopterygii mrpl411 mitochondrial ribosomal protein L41 63.21(n)
60(a)		   553805  NM_001020767.1  NP_001018603.1 
fruit fly
(Drosophila melanogaster)		 Insecta mRpL416
 mitochondrial ribosomal protein L41
 25(a)
 1 ↔ 1
 2R(11104529-11105118)
thale cress
(Arabidopsis thaliana)		 eudicotyledons AT5G400806
AT5G398006
(see all 3)		 Mitochondrial ribosomal protein L27
(see all 3)		 37(a)
36(a)
(see all 3)		 many → 1
many → 1
(see all 3)		 5(16039945-16041623)
5(15935464-15937132)
rice
(Oryza sativa)		 Liliopsida --
 conserved hypothetical protein
 22(a)
 1 ↔ 1
 2(24554307-24557377)


ENSEMBL Gene Tree for MRPL41 (if available)
TreeFam Gene Tree for MRPL41 (if available) 

Paralogs
for MRPL41 gene

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
  --

Genomic Variants
for MRPL41 gene

(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

10/54 NCBI SNPs in MRPL41 are shown (see all 54)     About this table
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance		Chr 9 posSequence#AA
Chg		TypeMore#Allele
freq		PopTotal
sample		More
----------
rs126846051,2
C,H,--109908456(+) ctgcaC/Atccag 1 -- us2k11Minor allele frequency- A:0.00NA 2
rs735697531,2
C,--109911220(+) TCTCAT/CGCAGA 2 -- us2k12Minor allele frequency- C:0.04WA 120
rs727651691,2
C,F,--109911400(+) ATACAG/CAGATG 2 -- us2k11Minor allele frequency- C:0.03NA 120
rs567156361,2
F,--140444379(+) CCCTCG/ACTGTG 3 -- us2k1 int13Minor allele frequency- A:0.13CSA WA 122
rs347541401,2
C,--140444505(+) CCAAG-/AAAGCC 3 -- us2k1 int10--------
rs1495471851,2
--140444514(+) AGCCAA/CGGGGC 3 -- us2k1 int10--------
rs1825140041,2
--140444530(+) AGCGCA/GGCAGA 3 -- us2k1 int10--------
rs1472083681,2
--140444532(+) CGCGGA/CAGAGC 3 -- us2k1 int10--------
rs787842971,2
C,F,--140444651(+) CCATGG/ACCAGA 3 -- us2k1 ut513Minor allele frequency- A:0.02WA NA EU 5944
rs1163104811,2
C,F,--140444678(+) AGGGGC/TGAAAA 3 -- us2k1 ut511Minor allele frequency- T:0.02WA 118

HapMap Linkage Disequilibrium report for MRPL41 (140445651 - 140447007 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
      Database of Genomic Variants (DGV) variations for MRPL41: --

SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MRPL41
DNA2.0 Custom Variant and Variant Library Synthesis for MRPL41

Disorders / Diseases
for MRPL41 gene

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section
MRPL41 for disorders           About GeneDecksing

OMIM gene information: 611846    OMIM disorders: --

2 diseases for MRPL41:    About MalaCards
duodenogastric reflux    breast cancer

Human Genome Epidemiology (HuGE) Navigator: MRPL41 (1 document)

Export disorders for MRPL41 gene to outside databases

Publications
for MRPL41 gene

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
About This Section

PubMed articles for MRPL41 gene, integrated from 9 sources (see all 22):
(articles sorted by number of sources associating them with MRPL41)		    Utopia: connect your pdf to the dynamic
world of online information

  1. The human mitochondrial ribosomal protein genes: mapping of 54 genes to the chromosomes and implications for human disorders. (PubMed id 11543634)1, 2, 3 Kenmochi N....Tanaka T. (2001)
  2. BMRP is a Bcl-2 binding protein that induces apoptosis. (PubMed id 15547950)1, 2, 9 Chintharlapalli S.R.... Gonzalez-Garcia M. (2005)
  3. Mitochondrial ribosomal protein L41 mediates serum starvation-induced cell-cycle arrest through an increase of p21(WAF1/CIP1). (PubMed id 16256947)1, 2, 9 Kim M.J.... Yoo Y.D. (2005)
  4. Mitochondrial ribosomal protein L41 suppresses cell growth in association with p53 and p27Kip1. (PubMed id 16024796)1, 2 Yoo Y.A.... Yoo Y.D. (2005)
  5. DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)1, 2 Humphray S.J.... Dunham I. (2004)
  6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
  7. The large subunit of the mammalian mitochondrial ribosome. Analysis of the complement of ribosomal proteins present. (PubMed id 11551941)1, 2 Koc E.C....Spremulli L.L. (2001)
  8. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
  9. Identification of a motif in BMRP required for interac tion with Bcl-2 by site-directed mutagenesis studies. (PubMed id 22711503)1 Conde J.A....Gonzalez-Garcia M. (2012)
  10. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)

External Searches for MRPL41 gene

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section
 ANDOR
Aliases
Free Text  
  Query String
PubMed
OMIM
NCBI Bookshelf
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Genome Databases showing MRPL41 gene

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 64975 HGNC: 14492 AceView: MRPL41 Ensembl:ENSG00000182154 euGenes: HUgn64975
ECgene: MRPL41 H-InvDB: MRPL41

Other Databases showing MRPL41 gene

(According to HUGE)
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   --

Specialized Databases showing MRPL41 gene

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for MRPL41 Pharmacogenomics, SNPs, Pathways

Intellectual Property
for MRPL41 gene

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for MRPL41 gene:
Search GeneIP for patents involving MRPL41

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



Products
for MRPL41 gene

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
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