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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

MRPL4 Gene

protein-coding   GIFtS: 56
GCID: GC19P010362

Mitochondrial Ribosomal Protein L4

Microbiology & Infectious Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Mitochondrial Ribosomal Protein L41 2
L4mt2 3
MRP-L42 3
39S Ribosomal Protein L4, Mitochondrial2
CGI-282

External Ids:    HGNC: 142761   Entrez Gene: 510732   Ensembl: ENSG000001053647   OMIM: 6118235   UniProtKB: Q9BYD33   

Export aliases for MRPL4 gene to outside databases

Previous GC identifers: GC19P010484 GC19P010585 GC19P010207 GC19P010223 GC19P009942


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for MRPL4 Gene:
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the
mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit.
They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is
reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain
a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and
sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a
39S subunit protein. Sequence analysis identified alternatively spliced variants that encode different protein
isoforms. (provided by RefSeq, Jul 2008)

GeneCards Summary for MRPL4 Gene: 
MRPL4 (mitochondrial ribosomal protein L4) is a protein-coding gene. Diseases associated with MRPL4 include pneumonia, and tuberculosis, and among its related super-pathways are Viral mRNA Translation. GO annotations related to this gene include structural constituent of ribosome.

Gene Wiki entry for MRPL4 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000019.9  NC_018930.2  NT_011295.11  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the MRPL4 gene promoter:
         AP-2alpha isoform 3   AP-2alpha isoform 2   CREB   RORalpha1   deltaCREB   c-Myb   AP-2alpha isoform 4   AP-2alpha   AP-2alphaA   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMRPL4 promoter sequence
   Search SABiosciences Chromatin IP Primers for MRPL4

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MRPL4


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19p13.2   Ensembl cytogenetic band:  19p13.2   HGNC cytogenetic band: 19p13.2

MRPL4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MRPL4 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19P010362:  view genomic region     (about GC identifiers)

Start:
10,362,577 bp from pter      End:
10,370,736 bp from pter
Size:
8,160 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: RM04_HUMAN, Q9BYD3 (See protein sequence)
Recommended Name: 39S ribosomal protein L4, mitochondrial  
Size: 311 amino acids; 34919 Da
Subcellular location: Mitochondrion (By similarity)
Sequence caution: Sequence=AAD27737.1; Type=Frameshift; Positions=128; Sequence=AAG02005.1; Type=Erroneous
initiation;
Secondary accessions: A6NNV7 Q9BW07 Q9H4N2 Q9Y317
Alternative splicing: 2 isoforms:  Q9BYD3-1   Q9BYD3-2   

Explore the universe of human proteins at neXtProt for MRPL4: NX_Q9BYD3

Explore proteomics data for MRPL4 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9BYD3

  • MRPL4 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    MRPL4 Protein Expression
    REFSEQ proteins (3 alternative transcripts): 
    NP_057040.2  NP_666499.1  NP_666500.1  

    ENSEMBL proteins: 
     ENSP00000468569   ENSP00000465635   ENSP00000253099   ENSP00000466050   ENSP00000465143  
     ENSP00000377334   ENSP00000466169   ENSP00000465050   ENSP00000306902  

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    Novus Biologicals MRPL4 Protein
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    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for MRPL4 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion IEA--
    GO:0005840ribosome IEA--

    MRPL4 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    MRPL: Mitochondrial ribosomal proteins / large subunits

    3 InterPro protein domains:
     IPR013005 Ribosomal_L4/L1e_bac-type
     IPR023574 Ribosomal_L4_dom
     IPR002136 Ribosomal_L4/L1e

    Graphical View of Domain Structure for InterPro Entry Q9BYD3

    ProtoNet protein and cluster: Q9BYD3

    UniProtKB/Swiss-Prot: RM04_HUMAN, Q9BYD3
    Similarity: Belongs to the ribosomal protein L4P family


    MRPL4 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003735structural constituent of ribosome IEA--
         
    MRPL4 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for MRPL4 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for MRPL4

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for MRPL4 
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    1 QIAGEN miScript miRNA Assays for microRNA that regulate MRPL4:
    hsa-miR-637
    SwitchGear 3'UTR luciferase reporter plasmidMRPL4 3' UTR sequence
    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MRPL4


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for MRPL4 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Viral mRNA Translation
    Ribosome0.59

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    1         Kegg Pathway  (Kegg details for MRPL4):
        Ribosome


    MRPL4 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MRPL4

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/266 Interacting proteins for MRPL4 (Q9BYD32, 3 ENSP000002530994) via UniProtKB, MINT, STRING, and/or I2D (see all 266)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    KRTAP4-12Q9BQ662, 3, ENSP000003775824MINT-68210 I2D: score=5 STRING: ENSP00000377582
    EIF2B1Q142322, 3MINT-65806 I2D: score=5 
    ICT1Q141972, 3, ENSP000003015854MINT-8079030 I2D: score=1 STRING: ENSP00000301585
    DDX24Q9GZR72, 3, ENSP000003286904MINT-65430 I2D: score=4 STRING: ENSP00000328690
    TIMM44O436153, ENSP000002705384I2D: score=1 STRING: ENSP00000270538
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006412translation IEA--

    MRPL4 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for MRPL4 (RM04)

    Search CenterWatch for drugs/clinical trials and news about MRPL4 / RM04

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for MRPL4 gene (3 alternative transcripts): 
    NM_015956.2  NM_146387.1  NM_146388.1  

    Unigene Cluster for MRPL4:

    Mitochondrial ribosomal protein L4
    Hs.279652  [show with all ESTs]
    Unigene Representative Sequence: NM_146388
    11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000592514 ENST00000591054 ENST00000253099 ENST00000590150 ENST00000590669
    ENST00000393733(uc002mnm.3 uc002mnn.3 uc002mno.3) ENST00000592071
    ENST00000588502 ENST00000588963 ENST00000590702 ENST00000307422
    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MRPL4
    1 QIAGEN miScript miRNA Assays for microRNA that regulate MRPL4:
    hsa-miR-637
    SwitchGear 3'UTR luciferase reporter plasmidMRPL4 3' UTR sequence
    Inhib. RNA
    Products:
         
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MRPL4
    Sirion Biotech Customized lentivirus for stable overexpression of MRPL4 
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      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MRPL4

    Additional mRNA sequence: 

    AB049635.1 AY007152.1 BC000756.2 BC009858.2 

    19 DOTS entries:

    DT.451301  DT.100824597  DT.91754151  DT.100824588  DT.100824582  DT.95258064  DT.91851574  DT.100824594 
    DT.100824590  DT.86854169  DT.95258067  DT.95258112  DT.95307769  DT.100824581  DT.100836094  DT.100838288 
    DT.121464275  DT.95308153  DT.91712172 

    24/367 AceView cDNA sequences (see all 367):

    CR617549 AL555515 AW246009 BM726686 BM851471 CR613991 BQ053263 BG697082 
    BX458353 CR620093 BI858479 BC009858 AW245052 BQ645306 CR621397 CR624166 
    BM558471 BE254724 AB049635 BM423492 BM818196 BM817765 BQ688415 BM796366 

    GeneLoc Exon Structure

    5/6 Alternative Splicing Database (ASD) splice patterns (SP) for MRPL4 (see all 6)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3a · 3b ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9
    SP1:                    -                 -           -                             -         
    SP2:                    -                 -           -                                       
    SP3:                                      -           -                                       
    SP4:                                      -           -                                       
    SP5:                    -                 -                                                   


    ECgene alternative splicing isoforms for MRPL4

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    MRPL4 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ATCGCACCAC
    MRPL4 Expression
    About this image


    See MRPL4 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for MRPL4

    SOURCE GeneReport for Unigene cluster: Hs.279652
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for MRPL4 gene from 8/18 species (see all 18)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Mrpl41 , 5 mitochondrial ribosomal protein L41, 5 79.37(n)1
    80.95(a)1
      9 (7.69 cM)5
    661631  NM_023167.21  NP_075656.21 
     210027375 
    lizard
    (Anolis carolinensis)
    Reptilia MRPL46
    mitochondrial ribosomal protein L4
    63(a)
    1 ↔ 1
    GL343692.1(168504-188853)
    African clawed frog
    (Xenopus laevis)
    Amphibia BJ075004.12   -- 75(n)    BJ075004.1 
    zebrafish
    (Danio rerio)
    Actinopterygii 570884532   -- 72.68(n)    57088453 
    fruit fly
    (Drosophila melanogaster)
    Insecta mRpL41 , 3 protein biosynthesis structural
    constituent of more3
    mitochondrial ribosomal protein L41
    43(a)3
    55.56(n)1
    54.32(a)1
      35F113
    494251  NM_080200.21  NP_524939.11 
    worm
    (Caenorhabditis elegans)
    Secernentea T23B12.23
    mrpl-41
    ribosomal protein3
    Protein MRPL-41
    40(a)3
    49.39(n)1
    49.09(a)1
      V(8469861-8471428)3
    1792301  NM_072780.41  NP_505181.11 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT2G200601 large subunit ribosomal protein L4 44.71(n)
    35.69(a)
      816525  NM_127564.2  NP_565463.1 
    rice
    (Oryza sativa)
    Liliopsida Os11g05857001 hypothetical protein 46.91(n)
    42.27(a)
      4350797  NM_001074697.1  NP_001068165.1 


    ENSEMBL Gene Tree for MRPL4 (if available)
    TreeFam Gene Tree for MRPL4 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/289 SNPs in MRPL4 are shown (see all 289)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1171317081,2
    C,F--10360745(+) AAAAAA/TAATAA 3 -- us2k11Minor allele frequency- T:0.02NA 120
    rs104159751,2
    C,A--10360748(+) aaaaaA/TaaTAA 3 -- us2k10--------
    rs1995061011,2
    --10360748(+) AAAAA-/TAATAA 3 -- us2k10--------
    rs1167742871,2
    C,F--10360776(+) TTTACA/GCCTTG 3 -- us2k11Minor allele frequency- G:0.07WA 118
    rs1146988501,2
    F--10360927(+) CCCTGG/AACTGG 3 -- us2k11Minor allele frequency- A:0.02WA 118
    rs81082181,2
    C,F,A--10361065(+) gagaaT/Ctgctt 3 -- us2k12Minor allele frequency- C:0.04WA EA 238
    rs1510096551,2
    C--10361147(+) ATTAGA/GCCGGG 3 -- us2k10--------
    rs1423111571,2
    --10361154(+) CGGGCG/TCGGTG 3 -- us2k10--------
    rs1867334651,2
    --10361210(+) ATCACA/CTGAGG 3 -- us2k10--------
    rs1118707751,2
    C--10361421(+) TAGCCG/AGGTGT 3 -- us2k11Minor allele frequency- A:0.50CSA 2

    HapMap Linkage Disequilibrium report for MRPL4 (10362577 - 10370736 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for MRPL4:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv911030CNV Loss21882294
    nsv911029CNV Loss21882294
    dgv3725n71CNV Loss21882294

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing MRPL4
    DNA2.0 Custom Variant and Variant Library Synthesis for MRPL4

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 611823    OMIM disorders: --

    2 diseases for MRPL4:    About MalaCards
    pneumonia    tuberculosis

    1 disease from the University of Copenhagen DISEASES database for MRPL4:
    Allergic rhinitis

    MRPL4 for disorders           About GeneDecksing

    Genetic Association Database (GAD): MRPL4
    Human Genome Epidemiology (HuGE) Navigator: MRPL4 (2 documents)

    Export disorders for MRPL4 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for MRPL4 gene, integrated from 9 sources (see all 22):
    (articles sorted by number of sources associating them with MRPL4)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Genetic variants in nuclear-encoded mitochondrial gen es influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (2010)
    2. Association between genetic variants in VEGF, ERCC3 a nd occupational benzene haematotoxicity. (PubMed id 19773279)1, 4 Hosgood H.D....Lan Q. (2009)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Structural compensation for the deficit of rRNA with proteins in the mammalian mitochondrial ribosome. Systematic analysis of protein components of the large ribosomal subunit from mammalian mitochondria. (PubMed id 11279069)1, 2 Suzuki T....Watanabe K. (2001)
    5. Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics. (PubMed id 10810093)1, 2 Lai C.H....Lin W. (2000)
    6. The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells. (PubMed id 23667531)1 Cox J.L....Rizzino A. (2013)
    7. p32/gC1qR is indispensable for fetal development and m itochondrial translation: importance of its RNA-binding ability. (PubMed id 22904065)1 Yagi M....Kang D. (2012)
    8. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    9. A bead-based approach for large-scale identification o f in vitro kinase substrates. (PubMed id 22113938)1 Zhang M....Zou H. (2011)
    10. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 51073 HGNC: 14276 AceView: MRPL4 Ensembl:ENSG00000105364 euGenes: HUgn51073
    ECgene: MRPL4 Kegg: 51073 H-InvDB: MRPL4

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for MRPL4 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for MRPL4 gene:
    Search GeneIP for patents involving MRPL4

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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