Home
GeneCards Guide
Suite
- MalaCards
- GeneALaCart
- GeneAnalytics
- GeneLoc
- GenesLikeMe
- VarElect
- PathCards
Terms of Use
- Terms of Use
- 3rd Party Notice
About Us
- GeneCards Team
- Our Publications
- Citing GeneCards
- Licensing Agreement
- Weizmann Institute
- LifeMap Sciences Inc
User Feedback
GeneCards Suite
- Affiliated Databases
  
  Premium Tools
  
  Learn more

Set Analyses:

VarElect

Advanced Search

MRPL38 Gene

protein-coding GIFtS: 50
GCID: GC17M073894

Mitochondrial Ribosomal Protein L38

Try our

MalaCards

disease database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, ¹⁰fRNAdb, ¹²H-InvDB, ¹³NCBI, ¹⁴NONCODE, and/or ¹⁵RNAdb)
About This Section

Aliases
Mitochondrial Ribosomal Protein L38¹ ²		MRP-L3²
MRP-L38² ³		RPML3²
39S Ribosomal Protein L38, Mitochondrial²		L38mt³
L38MT²

External Ids:	HGNC: 14033¹	Entrez Gene: 64978²	Ensembl: ENSG00000204316⁷	OMIM: 611844⁵	UniProtKB: Q96DV4³

Export aliases for MRPL38 gene to outside databases

Previous GC identifers: GC17U990214 GC17M076921 GC17M074358 GC17M074491 GC17M071406 GC17M069320

(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for MRPL38 Gene:

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the

mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit.

They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is

reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain

a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and

sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a

39S subunit protein. (provided by RefSeq, Jul 2008)

GeneCards Summary for MRPL38 Gene:

MRPL38 (mitochondrial ribosomal protein L38) is a protein-coding gene. An important paralog of this gene is PEBP4.

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence at NCBI GenBank:

NC_000017.10 NC_018928.2 NT_010783.16

Regulatory elements:

Regulatory transcription factor binding sites in the MRPL38 gene promoter:
ER-alpha AML1a HTF Tal-1beta Egr-4 GATA-2 PPAR-alpha Egr-2 CP2 ITF-2
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: MRPL38 promoter sequence

Search Chromatin IP Primers for MRPL38

Epigenetics:

DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MRPL38

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q25.3 Ensembl cytogenetic band: 17q25.1 HGNC cytogenetic band: 17q23-q25

MRPL38 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MRPL38 gene location

GeneLoc information about chromosome 17 GeneLoc Exon Structure

GeneLoc location for GC17M073894: view genomic region (about GC identifiers)

Start:	73,894,724 bp from pter	End:	73,905,899 bp from pter
Size:	11,176 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, ²neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, antibodies-online, and/or GeneTex,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
About This Section

UniProtKB/Swiss-Prot: RM38_HUMAN, Q96DV4 (See protein sequence)

Recommended Name: 39S ribosomal protein L38, mitochondrial precursor

Size: 380 amino acids; 44597 Da

Sequence caution: Sequence=AAH13311.1; Type=Erroneous initiation;

Secondary accessions: Q96Q66 Q9P0B9

Explore the universe of human proteins at neXtProt for MRPL38: NX_Q96DV4

Explore proteomics data for MRPL38 at MOPED

Post-translational modifications:

Ubiquitination² at Lys96, Lys107

Modification sites at PhosphoSitePlus

See MRPL38 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins: NP_115867.2

ENSEMBL proteins:

ENSP00000308275 ENSP00000387085

MRPL38 Human Recombinant Protein Products:

	Browse Purified and Recombinant Proteins at EMD Millipore
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	OriGene Purified Protein for MRPL38 OriGene Protein Over-expression Lysate for MRPL38 OriGene MassSpec for MRPL38 OriGene Custom Protein Services for MRPL38
	GenScript Custom Purified and Recombinant Proteins Services for MRPL38
	Novus Biologicals MRPL38 Protein Novus Biologicals MRPL38 Lysates
	Browse Sino Biological Recombinant Proteins Browse Sino Biological Cell Lysates
	Browse ProSpec Recombinant Proteins
	Cloud-Clone Corp. Proteins for MRPL38
	Search eBioscience for Proteins for MRPL38
	Search GeneTex for Proteins for MRPL38
	antibodies-online proteins for MRPL38 (4 products)
	antibodies-online peptides for MRPL38

MRPL38 Antibody Products:

	Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse R&D Systems for Antibodies
	Browse OriGene Antibodies OriGene Custom Antibody Services for MRPL38
	Novus Biologicals MRPL38 Antibodies
	Abcam antibodies for MRPL38
	Cloud-Clone Corp. Antibodies for MRPL38
	ThermoFisher Antibodies for MRPL38
	antibodies-online antibodies for MRPL38 (9 products)

MRPL38 Assay Products:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Assay Services for MRPL38
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for MRPL38
	Browse Enzo Life Sciences for kits & assays
	Cloud-Clone Corp. ELISAs for MRPL38 Cloud-Clone Corp. CLIAs for MRPL38
	Search eBioscience for ELISAs for MRPL38
	antibodies-online kits for MRPL38 (4 products)

(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GenesLikeMe)
About This Section

HGNC Gene Families:

MRPL: Mitochondrial ribosomal proteins / large subunits

1 InterPro protein domain:

IPR008914 PtdEtn-bd_prot_PEBP

Graphical View of Domain Structure for InterPro Entry Q96DV4

ProtoNet protein and cluster: Q96DV4

1 Blocks protein domain: IPB001858 Phosphatidylethanolamine-binding protein

Find genes that share domains with MRPL38 About GenesLikeMe

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene, Sets of similar genes according to GenesLikeMe)
About This Section

Phenotypes:
1 MGI mutant phenotype (inferred from 1 allele) (MGI details for Mrpl38):

no phenotypic analysis

Find genes that share phenotypes with MRPL38 About GenesLikeMe

Animal Models:

genOway: Develop your customized and physiologically relevant rodent model for MRPL38

miRNA Products:		miRTarBase miRNAs that target MRPL38: hsa-mir-421 (MIRT039380), hsa-mir-30c-5p (MIRT048000), hsa-mir-615-3p (MIRT040319)

		Block miRNA regulation of human, mouse, rat MRPL38 using miScript Target Protectors
		Search for qRT-PCR Assays for microRNAs that regulate MRPL38
		SwitchGear 3'UTR luciferase reporter plasmid: MRPL38 3' UTR sequence

Inhib. RNA Products:		OriGene RNAi products in human, mouse, rat for MRPL38
		Predesigned siRNA for gene silencing in human, mouse, rat MRPL38

Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for MRPL38

Clone Products:		OriGene clones in human, mouse for MRPL38 (see all 8) OriGene ORF clones in mouse, rat for MRPL38 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: MRPL38 (NM_032478)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for MRPL38
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MRPL38

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for MRPL38
		Browse ESI BIO Cell Lines and PureStem Progenitors for MRPL38

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MRPL38

(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene, Sets of similar genes according to GenesLikeMe)
About This Section

Subcellular locations from UniProtKB/Swiss-Prot

RM38_HUMAN, Q96DV4: Mitochondrion (By similarity)

Subcellular locations from COMPARTMENTS:

Compartment	Confidence
cytoskeleton	4
mitochondrion	4
cytosol	3
nucleus	1

About this image

Gene Ontology (GO): 4 cellular component terms: About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005737	cytoplasm	--	--
GO:0005739	mitochondrion	IEA	--
GO:0005840	ribosome	IEA	--
GO:0015629	actin cytoskeleton	--	--

Find genes that share ontologies with MRPL38 About GenesLikeMe

(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GenesLikeMe, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene, Sets of similar genes according to GenesLikeMe)
About This Section

Custom Pathway & Disease-focused RT² Profiler PCR Arrays for MRPL38
Interactions:

Search GeneGlobe Interaction Network for MRPL38

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

Selected Interacting proteins for MRPL38 (Q96DV4^{2, 3} ENSP00000308275⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 44)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
C14orf1	Q9UKR5²^,³	MINT-65128 I2D: score=5
HSPB3	Q12988²^,³	MINT-64107 I2D: score=5
PRIM1	P49642²^,³, ENSP00000350491⁴	MINT-65127 I2D: score=4 STRING: ENSP00000350491
UBE2H	P62256³, ENSP00000347836⁴	I2D: score=1 STRING: ENSP00000347836
SQSTM1	Q13501³	I2D: score=3

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, Sets of similar genes according to GenesLikeMe)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse compounds at ApexBio

Browse Tocris compounds for MRPL38 (RM38)

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
About This Section

REFSEQ mRNAs for MRPL38 gene:

NM_032478.3

Unigene Cluster for MRPL38:

Mitochondrial ribosomal protein L38

Hs.442609 [show with all ESTs]

Unigene Representative Sequence: BM926558

18 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000309352(uc010wso.1) ENST00000486101 ENST00000480203 ENST00000588620

ENST00000483393 ENST00000477371 ENST00000477023 ENST00000471434 ENST00000477736

ENST00000493104 ENST00000494179 ENST00000585475 ENST00000493383 ENST00000474548

ENST00000461602 ENST00000464758 ENST00000410030 ENST00000409963(uc002jpz.1)

miRNA Products:		Block miRNA regulation of human, mouse, rat MRPL38 using miScript Target Protectors
		Search for qRT-PCR Assays for microRNAs that regulate MRPL38
		SwitchGear 3'UTR luciferase reporter plasmid: MRPL38 3' UTR sequence

Inhib. RNA Products:		OriGene RNAi products in human, mouse, rat for MRPL38
		Predesigned siRNA for gene silencing in human, mouse, rat MRPL38

Clone Products:		OriGene clones in human, mouse for MRPL38 (see all 8) OriGene ORF clones in mouse, rat for MRPL38 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: MRPL38 (NM_032478)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for MRPL38
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MRPL38

Primer Products:		OriGene qPCR primer pairs and template standards for MRPL38 OriGene qSTAR qPCR primer pairs in human, mouse for MRPL38
		Pre-validated RT² qPCR Primer Assay in human, mouse, rat MRPL38
		QuantiTect SYBR Green Assays in human, mouse, rat MRPL38
		QuantiFast Probe-based Assays in human, mouse, rat MRPL38

Additional mRNA sequence:

AF161380.1 AK313283.1 BC013311.2 BC034460.1

18 DOTS entries:

DT.101984203 DT.449856 DT.95166381 DT.100791418 DT.92440931 DT.101959303 DT.95166368 DT.95217875

DT.121007965 DT.121007935 DT.121007836 DT.121007860 DT.121007983 DT.91724161 DT.95213831 DT.95166377

DT.95166380 DT.97816590

Selected AceView cDNA sequences (see all 450):

BM850106 AB058766 CD671273 BG830333 BE855557 AI566678 AI827499 BU951822

BI761920 AA937341 BG655930 AI719051 BU783950 CB164221 AA973892 AI912558

BU543028 AW303296 BC007570 AI126946 BM020701 BC013311 AK057261 BG656481

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GenesLikeMe, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE ¹MOPED, ²PaxDb, and ³MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

MRPL38 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>^2/3
CGAP TAG: ATTTCTTGCC

About this image

MRPL38 Protein expression data from MOPED¹, PaxDb² and MaxQB³:

About this image

MRPL38 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.442609

Custom PCR Arrays for MRPL38

Primer Products:		OriGene qPCR primer pairs and template standards for MRPL38 OriGene qSTAR qPCR primer pairs in human, mouse for MRPL38
		Pre-validated RT² qPCR Primer Assay in human, mouse, rat MRPL38
		QuantiTect SYBR Green Assays in human, mouse, rat MRPL38
		QuantiFast Probe-based Assays in human, mouse, rat MRPL38

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MRPL38

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for MRPL38 gene from Selected species (see all 17) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Mrpl38^{1 , 5}	mitochondrial ribosomal protein L38^{1, 5}	86.32(n)¹ 86.58(a)¹		11 (80.91 cM)⁵ 60441¹ NM_024177.3¹ NP_077139.2¹ 116131817⁵
chicken (Gallus gallus)	Aves	MRPL38¹	mitochondrial ribosomal protein L38	65.34(n) 64.55(a)		770172 NM_001114629.1 NP_001108101.1
lizard (Anolis carolinensis)	Reptilia	MRPL38⁶	mitochondrial ribosomal protein L38	62(a)	1 ↔ 1	2(113415193-113432042)
African clawed frog (Xenopus laevis)	Amphibia	BX844742.1²	--	73.15(n)		BX844742.1
zebrafish (Danio rerio)	Actinopterygii	Dr.11989²	Transcribed sequence with weak similarity to protein more	70.45(n)		AL909100.1
fruit fly (Drosophila melanogaster)	Insecta	mRpL38¹	mitochondrial ribosomal protein L38	54.17(n) 42.71(a)		32375 NM_078597.2 NP_511152.2
worm (Caenorhabditis elegans)	Secernentea	mrpl-38⁶	Protein MRPL-38 (mrpl-38) mRNA, complete cds	18(a)	1 ↔ 1	I(1019825-1029952) WBGene00021327

ENSEMBL Gene Tree for MRPL38 (if available)
TreeFam Gene Tree for MRPL38 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68,Sets of similar genes according to GenesLikeMe)
About This Section

Paralogs for MRPL38 gene

PEBP4² PEBP1²

2 SIMAP similar genes for MRPL38 using alignment to 3 protein entries: RM38_HUMAN (see all proteins):

HEL-S-34 PEBP1

Find genes that share paralogs with MRPL38 About GenesLikeMe

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, ⁴UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
About This Section

SNP ID	Valid	Clinical significance	Chr 17 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs201382082^1,2		--	73895246(+)	`AGAAGC/TTGGTG`	2	Q	syn¹		0	--	--	--	--
rs200049183^1,2		--	73895303(+)	`AAGCCA/GGCTGG`	2	A	syn¹		0	--	--	--	--
rs141522899^1,2	C	--	73895322(+)	`TTTCTT/GGGTGT`	2	/Q /P	mis¹		1		NA	4460
rs142772607^1,2	C	--	73895386(+)	`AGAAGA/GTAGAG`	1	--	int¹		0	--	--	--	--
rs201954650^1,2		--	73895393(+)	`AGAGAA/GCGTAT`	1	--	int¹		0	--	--	--	--
rs201107670^1,2	C	--	73895395(+)	`AGAGCG/ATATGA`	1	--	int¹		1		EU	367
rs200298025^1,2		--	73895613(+)	`GCGTGC/TGTCCT`	2	T A	mis¹		0	--	--	--	--
rs143444007^1,2	C	--	73895632(+)	`TCAATC/TGGCTG`	2	P	syn¹		0	--	--	--	--
rs145698092^1,2	F	--	73895649(+)	`CTTGAA/GGAGCA`	2	L F	mis¹		1		NA	4408
rs147988641^1,2	C	--	73895652(+)	`GAAGAA/GCAGGA`	2	L F	mis¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for MRPL38 (73894724 - 73905899 bp)

Structural Variations
Database of Genomic Variants (DGV) 7 variations for MRPL38: About this table

Variant ID	Type	Subtype	PubMed ID
nsv908823	CNV	Loss	21882294
nsv908820	CNV	Loss	21882294
nsv908822	CNV	Loss	21882294
nsv908821	CNV	Loss	21882294
dgv3267n71	CNV	Loss	21882294
dgv3264n71	CNV	Loss	21882294
nsv833545	CNV	Gain	17160897

Site Specific Mutation Identification with PCR Assays

SeqTarget long-range PCR primers for resequencing MRPL38

DNA2.0 Custom Variant and Variant Library Synthesis for MRPL38

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB, Sets of similar genes according to GenesLikeMe)
About This Section

OMIM gene information: 611844 OMIM disorders: --

Find genes that share disorders with MRPL38 About GenesLikeMe

Export disorders for MRPL38 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for MRPL38 gene, integrated from 10 sources (see all 20):
(articles sorted by number of sources associating them with MRPL38)

The human mitochondrial ribosomal protein genes: mapping of 54 genes to the chromosomes and implications for human disorders. (PubMed id 11543634)^{1, 2, 3} Kenmochi N.... Tanaka T. (Genomics 2001)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S.... Malek J. (Genome Res. 2004)
Quantitative study of the interactome of PKCIP involved in the EGF-induced tumor cell chemotaxis. (PubMed id 23402259)¹ Chen R....Zhang N. (J. Proteome Res. 2013)
A Y2H-seq approach defines the human protein methyltransferase interactome. (PubMed id 23455924)¹ Weimann M.... Stelzl U. (Nat. Methods 2013)
p32/gC1qR is indispensable for fetal development and mitochondrial translation: importance of its RNA-binding ability. (PubMed id 22904065)¹ Yagi M....Kang D. (Nucleic Acids Res. 2012)
The proteomic analysis of endogenous FAT10 substrates identifies p62/SQSTM1 as a substrate of FAT10ylation. (PubMed id 22797925)¹ Aichem A....Groettrup M. (J. Cell. Sci. 2012)
A census of human soluble protein complexes. (PubMed id 22939629)¹ Havugimana P.C....Emili A. (Cell 2012)
A bead-based approach for large-scale identification of in vitro kinase substrates. (PubMed id 22113938)¹ Zhang M....Zou H. (Proteomics 2011)
Initial characterization of the human central proteome. (PubMed id 21269460)² Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)¹ Wagner S.A....Choudhary C. (amp 2011)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 64978	HGNC: 14033	AceView: MRPL38andFBF1	Ensembl:ENSG00000204316	euGenes: HUgn64978
ECgene: MRPL38	H-InvDB: MRPL38

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for MRPL38	Pharmacogenomics, SNPs, Pathways

Intellectual Property for MRPL38 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for MRPL38 gene:
Search GeneIP for patents involving MRPL38

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, GeneTex, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from genOway)
About This Section


	EMD Millipore genomic analysis products

	Browse Antibodies		Browse Cell Culture Products
	Browse ELISAs		Browse Flow Cytometry Kits
	Browse Primer Pairs		Browse Enzyme Activity Assays/Reagents
	Browse ELISpot/FluoroSpot Kits/Development Modules		Browse TFB/Immunoprecipitation Assays
	Browse Apoptosis Detection Kits/Reagents		Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents
	Browse DNA Damage/Repair Kits/Reagents		Browse Luminex Assays
	Browse Cell Selection/Detection Kits/Reagents		Browse Secondary Antibodies/Controls/Staining Reagents
	Browse Recombinant/Natural Proteins		Browse Stem Cell Products
	Browse cDNA Clones		Browse Proteome Profiler Antibody Arrays

	Browse OriGene Antibodies		OriGene RNAi products in human, mouse, rat for MRPL38
	OriGene qPCR primer pairs and template standards for MRPL38		OriGene Protein Over-expression Lysate for MRPL38
	OriGene MassSpec for MRPL38		OriGene clones in human, mouse for MRPL38
	OriGene qSTAR qPCR primer pairs in human, mouse for MRPL38		OriGene Purified Protein for MRPL38
	OriGene ORF clones in mouse, rat for MRPL38		OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
	OriGene Custom Antibody Services for MRPL38		OriGene Custom Protein Services for MRPL38

	Block miRNA regulation of human, mouse, rat MRPL38 using miScript Target Protectors		SeqTarget long-range PCR primers for resequencing MRPL38
	DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MRPL38		Predesigned siRNA for gene silencing in human, mouse, rat MRPL38
	QuantiFast Probe-based Assays in human, mouse, rat MRPL38		QuantiTect SYBR Green Assays in human, mouse, rat MRPL38
	Custom PCR Arrays for MRPL38		Search Chromatin IP Primers for MRPL38
	Pre-validated RT² qPCR Primer Assay in human, mouse, rat MRPL38		Search GeneGlobe Interaction Network for MRPL38
	Regulatory tfbs in MRPL38 promoter

	GenScript Custom Purified and Recombinant Proteins Services for MRPL38		GenScript cDNA clones with any tag delivered in your preferred vector for MRPL38
	GenScript Custom Assay Services for MRPL38		GenScript Custom overexpressing Cell Line Services for MRPL38
	CloneReady with Over 120,000 Genes		Gene Synthesis: Any Gene in Any Vector
	Vector-based siRNA and miRNA, Ready for Transfection		Gene Mutant Library, Variants up to 10^11
	Plasmid Preparation		Custom Peptide Services

Search for Antibodies & Assays

Search Tocris compounds for MRPL38 (RM38)

	Browse Sino Biological Proteins
	Browse Sino Biological Cell Lysates
	Browse Sino Biological cDNA Clones
	4000+ Proteins
	Search Sino Biological for antibodies, proteins & pathways
	Protein Production Services
	Transfection Reagents
	Protein A/G/L resins
	Isotyping reagents

Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Tissue Slides
	MRPL38 antibodies
	MRPL38 proteins
	MRPL38 lysates

	Antibodies for MRPL38
	See all of Abcam's Antibodies, Kits and Proteins for MRPL38
	Custom Antibody / Protein Production Service
	Bulk Purchasing
	Advantages of Rabbit Monoclonal antibodies
	Abcam protocols and scientific support

Browse ProSpec Recombinant Proteins

	Proteins for MRPL38
	Antibodies for MRPL38
	ELISAs for MRPL38
	CLIAs for MRPL38

Browse ESI BIO Cell Lines and PureStem Progenitors for MRPL38

	Gene Synthesis
	Protein Engineering
	Variant Library Synthesis
	Codon Optimization
	Protein Production and Purification

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MRPL38

	SwitchGear 3'UTR luciferase reporter plasmids for MRPL38
	SwitchGear Promoter luciferase reporter plasmids for MRPL38

ThermoFisher Antibodies for MRPL38

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MRPL38

Browse compounds at ApexBio

Search Addgene for plasmids for MRPL38

	Search eBioscience for proteins for MRPL38
	Search eBioscience for elisas for MRPL38
	eBioscience FlowRNA Probe Sets

genOway: Develop your customized and physiologically relevant rodent model for MRPL38

	antibodies-online antibodies for MRPL38 (9 products)
	antibodies-online kits for MRPL38 (4 products)
	antibodies-online peptides for MRPL38
	antibodies-online proteins for MRPL38 (4 products)

Search GeneTex for proteins for MRPL38

GeneCards Home - Full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014 , 2 Nov 2014 , 8 Jan 2015 , 3 Feb 2015

View Random Gene

Category			(GIFtS: )
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes MRPL38 gene at Home site.

Version: 3.12.350 1 Mar 2015
hostname: 356977-web1.xennexinc.com index build: 128 solr: 1.4

GeneCards Suite

Advanced Search

Export list of displayed genes

MRPL38 Gene

Mitochondrial Ribosomal Protein L38

Aliases
for MRPL38 gene

Summaries
for MRPL38 gene

Genomic Views
for MRPL38 gene

Proteins
for MRPL38 gene

MRPL38 Human Recombinant Protein Products:

MRPL38 Antibody Products:

MRPL38 Assay Products:

Domains /
Families
for MRPL38 gene

Function
for MRPL38 gene

Localization
for MRPL38 gene

Pathways & Interactions
for MRPL38 gene

Drugs & Compounds
for MRPL38 gene

Transcripts
for MRPL38 gene

Expression
for MRPL38 gene

Orthologs
for MRPL38 gene

Paralogs
for MRPL38 gene

Genomic Variants
for MRPL38 gene

Disorders / Diseases
for MRPL38 gene

Publications
for MRPL38 gene

External Searches for MRPL38 gene

Genome Databases showing MRPL38 gene

Other Databases showing MRPL38 gene

Specialized Databases showing MRPL38 gene

Intellectual Property
for MRPL38 gene

Products
for MRPL38 gene

View Random Gene

GeneCards Suite

Advanced Search

Export list of displayed genes

MRPL38 Gene

Mitochondrial Ribosomal Protein L38

Aliasesfor MRPL38 gene

Summariesfor MRPL38 gene

Genomic Viewsfor MRPL38 gene

Proteinsfor MRPL38 gene

MRPL38 Human Recombinant Protein Products:

MRPL38 Antibody Products:

MRPL38 Assay Products:

Domains /Familiesfor MRPL38 gene

Functionfor MRPL38 gene

Localizationfor MRPL38 gene

Pathways & Interactionsfor MRPL38 gene

Drugs & Compoundsfor MRPL38 gene

Transcriptsfor MRPL38 gene

Expression for MRPL38 gene

Orthologsfor MRPL38 gene

Paralogsfor MRPL38 gene

Genomic Variantsfor MRPL38 gene

Disorders / Diseasesfor MRPL38 gene

Publicationsfor MRPL38 gene

External Searches for MRPL38 gene

Genome Databases showing MRPL38 gene

Other Databases showing MRPL38 gene

Specialized Databases showing MRPL38 gene

Intellectual Propertyfor MRPL38 gene

Productsfor MRPL38 gene

View Random Gene

Aliases
for MRPL38 gene

Summaries
for MRPL38 gene

Genomic Views
for MRPL38 gene

Proteins
for MRPL38 gene

Domains /
Families
for MRPL38 gene

Function
for MRPL38 gene

Localization
for MRPL38 gene

Pathways & Interactions
for MRPL38 gene

Drugs & Compounds
for MRPL38 gene

Transcripts
for MRPL38 gene

Expression
for MRPL38 gene

Orthologs
for MRPL38 gene

Paralogs
for MRPL38 gene

Genomic Variants
for MRPL38 gene

Disorders / Diseases
for MRPL38 gene

Publications
for MRPL38 gene

Intellectual Property
for MRPL38 gene

Products
for MRPL38 gene