Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

MRPL36 Gene

protein-coding   GIFtS: 48
GCID: GC05M001851

Mitochondrial Ribosomal Protein L36

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Mitochondrial Ribosomal Protein L361 2     39S Ribosomal Protein L361
Putative BRCA1-Interacting Protein1 2     mitochondrial1
BRIP12 3     39S Ribosomal Protein L36, Mitochondrial2
L36mt2 3     PRPL362
MRP-L362 3     RPMJ2
BRCA1-Interacting Protein 12 3     

External Ids:    HGNC: 144901   Entrez Gene: 649792   Ensembl: ENSG000001714217   OMIM: 6118425   UniProtKB: Q9P0J63   

Export aliases for MRPL36 gene to outside databases

Previous GC identifers: GC05M001939 GC05M001831


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for MRPL36 Gene:
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the
mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit.
They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is
reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain
a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and
sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a
39S subunit protein. A pseudogene corresponding to this gene is found on chromosome 2p. (provided by RefSeq, Jul
2008)

GeneCards Summary for MRPL36 Gene: 
MRPL36 (mitochondrial ribosomal protein L36) is a protein-coding gene. Diseases associated with MRPL36 include genital herpes, and wolf-hirschhorn syndrome, and among its related super-pathways are Viral mRNA Translation. GO annotations related to this gene include structural constituent of ribosome.

UniProtKB/Swiss-Prot: RM36_HUMAN, Q9P0J6
Function: Component of the large subunit of the mitochondrial ribosome (Potential)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000005.9  NC_018916.2  NT_006576.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the MRPL36 gene promoter:
         ER-alpha   RFX1   Pax-2   MIF-1   Pax-2a   PPAR-gamma1   c-Myb   Msx-1   ZIC2/Zic2   PPAR-gamma2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMRPL36 promoter sequence
   Search SABiosciences Chromatin IP Primers for MRPL36

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MRPL36


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5p15.3   Ensembl cytogenetic band:  5p15.33   HGNC cytogenetic band: 5p15.3

MRPL36 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MRPL36 gene location

GeneLoc information about chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05M001851:  view genomic region     (about GC identifiers)

Start:
1,798,499 bp from pter      End:
1,801,480 bp from pter
Size:
2,982 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: RM36_HUMAN, Q9P0J6 (See protein sequence)
Recommended Name: 39S ribosomal protein L36, mitochondrial precursor  
Size: 103 amino acids; 11784 Da
Subcellular location: Mitochondrion
Sequence caution: Sequence=AAF04788.1; Type=Erroneous initiation;
Secondary accessions: A4UCS0 B2R4Z2 Q3SWV6 Q9UKL7

Explore the universe of human proteins at neXtProt for MRPL36: NX_Q9P0J6

Explore proteomics data for MRPL36 at MOPED 

MRPL36 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

MRPL36 Protein Expression

REFSEQ proteins: NP_115868.1  
ENSEMBL proteins: 
 ENSP00000423152   ENSP00000427152   ENSP00000423399   ENSP00000372093   ENSP00000424366  

Human Recombinant Protein Products for MRPL36: 
Browse Purified and Recombinant Proteins at EMD Millipore
Browse R&D Systems for human recombinant proteins
Browse recombinant and purified proteins available from Enzo Life Sciences
OriGene Purified Protein for MRPL36
OriGene Protein Over-expression Lysate for MRPL36
OriGene MassSpec for MRPL36 
OriGene Custom Protein Services for MRPL36
GenScript Custom Purified and Recombinant Proteins Services for MRPL36
Novus Biologicals MRPL36 Lysates
Browse Sino Biological Recombinant Proteins
Browse Sino Biological Cell Lysates 
Browse ProSpec Recombinant Proteins
Cloud-Clone Corp. Proteins for MRPL36 

Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005622intracellular ----
GO:0005739mitochondrion ----
GO:0005762mitochondrial large ribosomal subunit NAS11279069
GO:0005840ribosome ----

MRPL36 for ontologies           About GeneDecksing



MRPL36 Antibody Products: 
Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
Browse R&D Systems for Antibodies
Browse OriGene Antibodies
OriGene Custom Antibody Services for MRPL36
GenScript Custom Superior Antibodies Services for MRPL36
Novus Biologicals MRPL36 Antibodies
Abcam antibodies for MRPL36
Cloud-Clone Corp. Antibodies for MRPL36 
Search ThermoFisher Antibodies for MRPL36
Search LSBio for Antibodies for MRPL36 

Assay Products for MRPL36: 
Browse Kits and Assays available from EMD Millipore
OriGene Custom Assay Services for MRPL36
Browse R&D Systems for biochemical assays
GenScript Custom Assay Services for MRPL36
Browse Enzo Life Sciences for kits & assays
Cloud-Clone Corp. ELISAs for MRPL36 
Cloud-Clone Corp. CLIAs for MRPL36


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section
HGNC Gene Families: 
MRPL: Mitochondrial ribosomal proteins / large subunits

1 InterPro protein domain:
 IPR000473 Ribosomal_L36

Graphical View of Domain Structure for InterPro Entry Q9P0J6

ProtoNet protein and cluster: Q9P0J6

1 Blocks protein domain: IPB000473 Ribosomal protein L36

UniProtKB/Swiss-Prot: RM36_HUMAN, Q9P0J6
Similarity: Belongs to the ribosomal protein L36P family


MRPL36 for domains           About GeneDecksing


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
About This Section

Molecular Function:

     UniProtKB/Swiss-Prot Summary: RM36_HUMAN, Q9P0J6
Function: Component of the large subunit of the mitochondrial ribosome (Potential)

     Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0003735structural constituent of ribosome IEA--
     
MRPL36 for ontologies           About GeneDecksing


Animal Models:
   inGenious Targeting Laboratory - Custom generated mouse model solutions for MRPL36 
   inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for MRPL36

   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for MRPL36 
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for MRPL36 

miRNA
Products:
    
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MRPL36
Search QIAGEN for miScript miRNA Assays for microRNAs that regulate MRPL36
SwitchGear 3'UTR luciferase reporter plasmidMRPL36 3' UTR sequence
Inhib. RNA
Products:
    
Browse for Gene Knock-down Tools from EMD Millipore
OriGene RNAi products in human, mouse, rat for MRPL36
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MRPL36

Gene Editing
Products:
DNA2.0 Custom Protein Engineering Service for MRPL36
Sirion Biotech Customized adenovirus for overexpression of MRPL36

Clone
Products:
     
Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
OriGene clones in human, mouse for MRPL36 (see all 7)
OriGene ORF clones in mouse, rat for MRPL36
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: MRPL36 (NM_032479)
Browse Sino Biological Human cDNA Clones
DNA2.0 Custom Codon Optimized Gene Synthesis Service for MRPL36
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MRPL36
Sirion Biotech Customized lentivirus for stable overexpression of MRPL36 
                     Customized lentivirus expression plasmids for stable overexpression of MRPL36 

Cell Line
Products:
     
GenScript Custom overexpressing Cell Line Services for MRPL36
Search LifeMap BioReagents cell lines for MRPL36
In Situ Assay
Products:
   

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MRPL36


(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
About This Section

SuperPaths for MRPL36 About                                                                                                See pathways by source

SuperPathContained pathways About
1Viral mRNA Translation
Ribosome0.59

Pathways by source                                                                                                                                                                 See SuperPaths
Show all pathways



1         Kegg Pathway  (Kegg details for MRPL36):
    Ribosome


MRPL36 for pathways           About GeneDecksing

Interactions:

    Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MRPL36

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

5/27 Interacting proteins for MRPL36 (Q9P0J63 ENSP000003720934) via UniProtKB, MINT, STRING, and/or I2D (see all 27)
InteractantInteraction Details
GeneCardExternal ID(s)
BRCA1P383983, ENSP000003502834I2D: score=1 STRING: ENSP00000350283
RRASP103013, ENSP000002467924I2D: score=2 STRING: ENSP00000246792
MRPL3ENSP000002649954STRING: ENSP00000264995
RPS16ENSP000002514534STRING: ENSP00000251453
UPF1ENSP000002628034STRING: ENSP00000262803
About this table

Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0006412translation NAS11279069

MRPL36 for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section
Browse Small Molecules at EMD Millipore
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for MRPL36 (RM36)

Search CenterWatch for drugs/clinical trials and news about MRPL36 / RM36

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for MRPL36 gene: 
NM_032479.3  

Unigene Cluster for MRPL36:

Mitochondrial ribosomal protein L36
Hs.719465  [show with all ESTs]
Unigene Representative Sequence: BG250351
5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000505059(uc003jcx.4) ENST00000505818 ENST00000508987 ENST00000382647
ENST00000510999
miRNA
Products:
     
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MRPL36
Search QIAGEN for miScript miRNA Assays for microRNAs that regulate MRPL36
SwitchGear 3'UTR luciferase reporter plasmidMRPL36 3' UTR sequence
Inhib. RNA
Products:
     
Browse for Gene Knock-down Tools from EMD Millipore
OriGene RNAi products in human, mouse, rat for MRPL36
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MRPL36
Clone
Products:
     
OriGene clones in human, mouse for MRPL36 (see all 7)
OriGene ORF clones in mouse, rat for MRPL36
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: MRPL36 (NM_032479)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for MRPL36
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MRPL36
Sirion Biotech Customized lentivirus for stable overexpression of MRPL36 
                     Customized lentivirus expression plasmids for stable overexpression of MRPL36 
Primer
Products:
    
OriGene qPCR primer pairs and template standards for MRPL36
OriGene qSTAR qPCR primer pairs in human, mouse for MRPL36
SABiosciences RT2 qPCR Primer Assay in human, mouse, rat MRPL36
  QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MRPL36
  QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MRPL36

Additional mRNA sequence: 

AB049654.1 AF151109.1 AF155653.1 AK312001.1 BC020642.1 BC104652.1 EF036487.1 

6 DOTS entries:

DT.75192658  DT.95369944  DT.91752418  DT.91752435  DT.95186808  DT.99971246 

24/166 AceView cDNA sequences (see all 166):

BQ012845 AA830635 AW187987 AA478610 NM_032479 AA503830 AW572997 AI052480 
BM703966 BQ007463 AA262336 AI598208 BQ012351 AA977298 AA443024 BC020642 
AA904619 BG027687 AA349759 BX111462 H77596 CF529678 AI089399 AB049654 

GeneLoc Exon Structure

2 Alternative Splicing Database (ASD) splice patterns (SP) for MRPL36    About this scheme

ExUns: 1a · 1b · 1c ^ 2a · 2b
SP1:                              
SP2:              -               


ECgene alternative splicing isoforms for MRPL36

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

MRPL36 expression in normal human tissues (normalized intensities)      MRPL36 embryonic expression: see
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: GCAAATCTTT
MRPL36 Expression
About this image


MRPL36 expression in embryonic tissues and stem cells    About this table
Data from LifeMap, the Embryonic Development and Stem Cells Database 
 5/4 selected tissues (see all 4) fully expand
 
 Adipose (Muscoskeletal System)
         Body Subcutaneous White Adipose
 
 Bone (Muscoskeletal System)
         BONE MARROW   
 
 Blood (Muscoskeletal System)
         BONE MARROW   
 
 Adrenal Gland (Endocrine System)

See MRPL36 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for MRPL36

SOURCE GeneReport for Unigene cluster: Hs.719465
    SABiosciences Custom PCR Arrays for MRPL36
Primer
Products:
OriGene qPCR primer pairs and template standards for MRPL36
OriGene qSTAR qPCR primer pairs in human, mouse for MRPL36
SABiosciences RT2 qPCR Primer Assay in human, mouse, rat MRPL36
QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MRPL36
QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MRPL36
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MRPL36

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals and fungi.

Orthologs for MRPL36 gene from 5/10 species (see all 10)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Mrpl361 , 5 mitochondrial ribosomal protein L361, 5 68.37(n)1
62.24(a)1
  13 (39.71 cM)5
940661  NM_053163.11  NP_444393.11 
 733310095 
lizard
(Anolis carolinensis)
Reptilia MRPL366
Ribosomal protein
75(a)
1 ↔ 1
4(68480488-68589301)
zebrafish
(Danio rerio)
Actinopterygii mrpl366
mitochondrial ribosomal protein L36
30(a)
1 ↔ 1
19(28769785-28775878)
fruit fly
(Drosophila melanogaster)
Insecta mRpL366
mitochondrial ribosomal protein L36
28(a)
1 ↔ 1
3L(8117684-8118232)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes RTC6(YPL183W-A)4 Protein involved translation; mutants have defects more   --   16(199095-199376) 855918  NP_015141.1 


ENSEMBL Gene Tree for MRPL36 (if available)
TreeFam Gene Tree for MRPL36 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
  --

(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

10/75 SNPs in MRPL36 are shown (see all 75)    About this table     
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 5 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs42779511,2
C,F,A,H--1798022(+) CTAGGG/TACTGA 1 -- ds50019Minor allele frequency- T:0.20NS EA NA WA 780
rs1146779121,2
F--1798036(+) AGTGCG/AGTAGA 1 -- ds50011Minor allele frequency- A:0.03WA 118
rs1458208041,2
C--1798049(+) TGACAC/TGCTGG 1 -- ds50010--------
rs1384586921,2
--1798106(+) TCTCTC/TGGGAC 1 -- ds50010--------
rs1165767871,2
F--1798111(+) CGGGAC/GACTCT 1 -- ds50011Minor allele frequency- G:0.03WA 118
rs1881247381,2
C--1798117(+) ACTCTC/TGGGAA 1 -- ds50010--------
rs45886291,2
C,F,H--1798138(+) GGGCAG/ATGCAA 1 -- ds500122Minor allele frequency- A:0.21NS EA NA WA CSA 2755
rs42750101,2
C,F,H--1798203(+) AGACCC/TCAGAC 1 -- ds50018Minor allele frequency- T:0.17NS EA WA CSA NA 649
rs100850111,2
C,F,A,H--1798243(+) TCCTGC/Tagtta 1 -- ds500123Minor allele frequency- T:0.13NS EA NA WA 2532
rs593881491,2
F--1798262(+) CAGATC/AAGACA 1 -- ds50011Minor allele frequency- A:0.08WA 118

HapMap Linkage Disequilibrium report for MRPL36 (1798499 - 1801480 bp)

Structural Variations
      Database of Genomic Variants (DGV) variations for MRPL36: --
SABiosciences Cancer Mutation PCR Assays
SeqTarget long-range PCR primers for resequencing MRPL36
DNA2.0 Custom Variant and Variant Library Synthesis for MRPL36

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section
OMIM gene information: 611842    OMIM disorders: --

2 diseases for MRPL36:    About MalaCards
genital herpes    wolf-hirschhorn syndrome


MRPL36 for disorders           About GeneDecksing

Genetic Association Database (GAD): MRPL36
Human Genome Epidemiology (HuGE) Navigator: MRPL36 (1 document)

Export disorders for MRPL36 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
About This Section

PubMed articles for MRPL36 gene, integrated from 9 sources (see all 14):
(articles sorted by number of sources associating them with MRPL36)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Genetic variants in nuclear-encoded mitochondrial gen es influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (2010)
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
  3. Structural compensation for the deficit of rRNA with proteins in the mammalian mitochondrial ribosome. Systematic analysis of protein components of the large ribosomal subunit from mammalian mitochondria. (PubMed id 11279069)1, 2 Suzuki T....Watanabe K. (2001)
  4. The human mitochondrial ribosomal protein genes: mapping of 54 genes to the chromosomes and implications for human disorders. (PubMed id 11543634)1, 3 Kenmochi N....Tanaka T. (2001)
  5. Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning. (PubMed id 10931946)1, 2 Hu R.-M.... Chen J.-L. (2000)
  6. Global identification of modular cullin-RING ligase su bstrates. (PubMed id 21963094)1 Emanuele M.J....Elledge S.J. (2011)
  7. Association of LETM1 and MRPL36 contributes to the regulation of mitochondrial ATP production and necrotic cell death. (PubMed id 19318571)1 Piao L....Park J. (2009)
  8. Protein interaction data set highlighted with human Ras-MAPK/PI3K signaling pathways. (PubMed id 18624398)1 Wang J....He F. (2008)
  9. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (2007)
  10. BACH1 is a DNA repair protein supporting BRCA1 damage response. (PubMed id 16462773)1 Peng M....Cantor S.B. (2006)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section
 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section
Entrez Gene: 64979 HGNC: 14490 AceView: MRPL36 Ensembl:ENSG00000171421 euGenes: HUgn64979
ECgene: MRPL36 Kegg: 64979 H-InvDB: MRPL36

(According to HUGE)
About This Section
  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
NameDescription
PharmGKB entry for MRPL36 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
About This Section
Patent Information for MRPL36 gene:
Search GeneIP for patents involving MRPL36

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
About This Section

 
 EMD Millipore Custom Antibody & Bulk Services
 EMD Millipore Preclinical / Clinical Development Services
 EMD Millipore Immunoassay Services
 EMD Millipore Target Screening & Profiling Services

  
 Browse Antibodies   Browse Cell Culture Products  
 Browse ELISAs   Browse Flow Cytometry Kits  
 Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
 Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
 Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
 Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
 Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
 Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
 Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
 Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
 Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for MRPL36  
 OriGene qPCR primer pairs and template standards for MRPL36   OriGene Protein Over-expression Lysate for MRPL36  
 OriGene MassSpec something-or-other for MRPL36   OriGene clones in human, mouse for MRPL36  
 OriGene qSTAR qPCR primer pairs in human, mouse for MRPL36   OriGene Purified Protein for MRPL36  
 OriGene ORF clones in mouse, rat for MRPL36   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
 OriGene Custom Antibody Services for MRPL36   OriGene Custom Protein Services for MRPL36  

 
 
 QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat MRPL36
 QIAGEN SeqTarget long-range PCR primers for resequencing MRPL36
 QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MRPL36
 QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MRPL36
 QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MRPL36
 QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MRPL36
 GenScript Custom Purified and Recombinant Proteins Services for MRPL36 GenScript cDNA clones with any tag delivered in your preferred vector for MRPL36
 GenScript Custom Assay Services for MRPL36 GenScript Custom Superior Antibodies Services for MRPL36
 GenScript Custom overexpressing Cell Line Services for MRPL36 CloneReady with Over 120,000 Genes
 Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
 Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
 Custom Peptide Services
 Search for Antibodies & Assays

 Regulatory tfbs in MRPL36 promoter
 Search Chromatin IP Primers for MRPL36
 RT2 qPCR Primer Assay in human, mouse, rat MRPL36
 Search GNC Networks for MRPL36
 SABiosciences Custom PCR Arrays for MRPL36
 Search Tocris compounds for MRPL36 (RM36)
 Browse Sino Biological Proteins and Antibodies
 Browse Sino Biological Cell Lysates
 Browse Sino Biological cDNA Clones
 4000+ Proteins
 Search Sino Biological for antibodies, proteins & pathways
 Protein Production Services
 Transfection Reagents
 Protein A/G/L resins
 Isotyping reagents
 Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
 Novus Tissue Slides
 MRPL36 antibodies
 MRPL36 lysates
 Antibodies for MRPL36
 See all of Abcam's Antibodies, Kits and Proteins for MRPL36
 Custom Antibody / Protein Production Service
 Bulk Purchasing
 Advantages of Rabbit Monoclonal antibodies
 Abcam protocols and scientific support
 Browse ProSpec Recombinant Proteins




 Proteins for MRPL36
 Antibodies for MRPL36
 ELISAs for MRPL36
 CLIAs for MRPL36
 Search LifeMap BioReagents cell lines for MRPL36
 Gene Synthesis
 Protein Engineering
 Variant Library Synthesis
 Codon Optimization
 Protein Production and Purification
 Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MRPL36
 SwitchGear 3'UTR luciferase reporter plasmids for MRPL36
 SwitchGear Promoter luciferase reporter plasmids for MRPL36
 Search ThermoFisher Antibodies for MRPL36
 Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MRPL36
 inGenious Targeting Laboratory - Custom generated mouse model solutions for MRPL36
 inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for MRPL36
Customized:
 lentivirus for stable overexpression of MRPL36
 lentivirus expression plasmids for stable overexpression of MRPL36
 adenovirus for overexpression of MRPL36
 Search LSBio for Antibodies for MRPL36
Customized transgenic rodents for:
 Humanization
 Biomarker expression
 Off-target effect monitoring
 Translational medicine
 Tissue-specific gene expresssion
 Time-controlled gene expresssion
       
GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

View Random Gene

Category
(GIFtS: 73)
transforming growth factor, beta 1
GIFtS Group
The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes      Disease genes      MRPL36 gene at Home site.
hostname: 356980-web2.xennexinc.com index build: 106 solr: 1.4