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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

MRPL22 Gene

protein-coding   GIFtS: 48
GCID: GC05P154300

mitochondrial ribosomal protein L22
 Explore 1 disease affiliated with
MRPL22 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for MRPL22    

Aliases
for MRPL22 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Mitochondrial Ribosomal Protein L221 2     L25mt2 3
MRP-L251 2 3     MRP-L222 3
RPML251 2 3     HSPC1581
39S Ribosomal Protein L25, Mitochondrial2 3     39S Ribosomal Protein L22, Mitochondrial2
L22mt2 3     MRPL253

External Ids:    HGNC: 144801   Entrez Gene: 290932   Ensembl: ENSG000000825157   OMIM: 6118355   UniProtKB: Q9NWU53   

Export aliases for MRPL22 gene to outside databases

Previous GC identifers: GC05P154413 GC05P154916 GC05P154303 GC05P154349 GC05P149462


Summaries
for MRPL22 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for MRPL22:
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the
mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They
have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed.
Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA.
Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in
biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein
that belongs to the L22 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 4q.
Two transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq, Jul 2008)

Gene Wiki entry for MRPL22


Genomic Views
for MRPL22 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000005.9  NC_018916.1  NT_029289.11  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the MRPL22 gene promoter:
         Sox5   NF-1   AP-1   NRSF form 1   NRSF form 2   Cdc5   Evi-1   E47   FAC1   Hand1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: MRPL22 promoter sequence
   Search SABiosciences Chromatin IP Primers for MRPL22

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MRPL22


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5q33.2   Ensembl cytogenetic band:  5q33.2   HGNC cytogenetic band: 5q33.2

MRPL22 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MRPL22 gene location

GeneLoc information about chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05P154300:  view genomic region     (about GC identifiers)

Start:
 154,320,630 bp from pter      End:
 154,348,971 bp from pter
Size:
 28,342 bases      Orientation:
 plus strand

Proteins
for MRPL22 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: RM22_HUMAN, Q9NWU5 (See protein sequence)
Recommended Name: 39S ribosomal protein L22, mitochondrial precursor  
Size: 206 amino acids; 23641 Da
Subcellular location: Mitochondrion (By similarity)
Sequence caution: Sequence=AAF29122.1; Type=Frameshift; Positions=197;
Secondary accessions: A6NGJ8 Q5H9Q1 Q96Q51 Q9P006
Alternative splicing: 3 isoforms:  Q9NWU5-1   Q9NWU5-2   Q9NWU5-3   

Explore the universe of human proteins at neXtProt for MRPL22: NX_Q9NWU5

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9NWU5

    • MRPL22 Protein expression data from MOPED and PaxDb:    About this image 
    MRPL22 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001014990.1  NP_054899.2  

    ENSEMBL proteins: 
     ENSP00000431040   ENSP00000265229   ENSP00000411177   ENSP00000429039   ENSP00000430648  

    Human Recombinant Protein Products for MRPL22: 
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    Novus Biologicals MRPL22 Protein
    Novus Biologicals MRPL22 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for MRPL22

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion ISS--
    GO:0015934large ribosomal subunit IEA--

    MRPL22 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for MRPL22

    Protein Domains /
    Families
    for MRPL22 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    MRPL22 for domains           About GeneDecksing

    2 InterPro domains/families:
     IPR005727 Ribosomal_L22_bac/chlpt-type
     IPR001063 Ribosomal_L22

    Graphical View of Domain Structure for InterPro Entry Q9NWU5

    ProtoNet protein and cluster: Q9NWU5

    1 Blocks protein family: IPB001063 Ribosomal protein L22/L17

    UniProtKB/Swiss-Prot: RM22_HUMAN, Q9NWU5
    Similarity: Belongs to the ribosomal protein L22P family


    Function
    for MRPL22 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003735structural constituent of ribosome IEA--
         
    MRPL22 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for MRPL22 

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MRPL22
    8/12 QIAGEN miScript miRNA Assays for microRNAs that regulate MRPL22 (see all 12):
    hsa-miR-4306 hsa-miR-548o hsa-miR-218 hsa-miR-1205 hsa-miR-199a-5p hsa-miR-1323 hsa-miR-1909* hsa-miR-185
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MRPL22 (see all 7)
    OriGene shRNA RFP: MRPL22
    OriGene siRNA: MRPL22
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    Sirion Biotech Custom design and validation of potent shRNA sequences against MRPL22 

    Gene Editing
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    Sirion Biotech Customized adenovirus for overexpression of MRPL22 
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    Clone
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MRPL22 

    Cell Line
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    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MRPL22


    Pathways & Interactions
    for MRPL22 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MRPL22

    STRING Interaction Network Preview (showing 5 interactants - click image to see 23)

    5/239 Interacting proteins for MRPL22 (Q9NWU52, 3 ENSP000004111774) via UniProtKB, MINT, STRING, and/or I2D (see all 239)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ICT1Q141972, 3, ENSP000003015854MINT-8079030 I2D: score=1 STRING: ENSP00000301585
    MRPL16Q9NX202, ENSP000003001514MINT-8079030 STRING: ENSP00000300151
    MRPL12P528152, ENSP000003338374MINT-8079030 STRING: ENSP00000333837
    MRPL19P494062, ENSP000003774864MINT-8079030 STRING: ENSP00000377486
    MRPL20Q9BYC92, ENSP000003410824MINT-8079030 STRING: ENSP00000341082
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006412translation IEA--

    MRPL22 for ontologies           About GeneDecksing



    Drugs & Compounds
    for MRPL22 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for MRPL22
    Search CenterWatch for drugs/clinical trials and news about MRPL22 / RM22 

    Transcripts
    for MRPL22 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for MRPL22 gene (2 alternative transcripts): 
    NM_001014990.2  NM_014180.3  

    Unigene Cluster for MRPL22:

    Mitochondrial ribosomal protein L22
    Hs.483924  [show with all ESTs]
    Unigene Representative Sequence: NM_014180
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000523037(uc003lvy.4 uc003lvz.4) ENST00000265229 ENST00000439747
    ENST00000522038 ENST00000519059 ENST00000520040 ENST00000518364

    miRNA
    Products:             		Browse 3'-UTR reporter clones for miRNA target validation
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MRPL22
    8/12 QIAGEN miScript miRNA Assays for microRNAs that regulate MRPL22 (see all 12):
    hsa-miR-4306 hsa-miR-548o hsa-miR-218 hsa-miR-1205 hsa-miR-199a-5p hsa-miR-1323 hsa-miR-1909* hsa-miR-185
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:             		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MRPL22 (see all 7)
    OriGene shRNA RFP: MRPL22
    OriGene siRNA: MRPL22
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MRPL22
    Sirion Biotech Custom design and validation of potent shRNA sequences against MRPL22 
    Clone
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    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MRPL22 (see all 3)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector (see all 2): MRPL22 (NM_014180)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MRPL22
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MRPL22 
    Primer
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    Browse OriGene validated miRNA SYBR primer pairs
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MRPL22
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MRPL22

    Additional cDNA sequence: 

    AF161507.1 AK000601.1 AK097880.1 AK302784.1 BC012565.1 CR933679.1 

    12 DOTS entries:

    DT.315890  DT.97845306  DT.92385210  DT.95276207  DT.97845308  DT.95276208  DT.95276209  DT.100760591 
    DT.91760095  DT.91760100  DT.95276211  DT.91760091 

    24/228 AceView cDNA sequences (see all 228):

    BM662504 BM781487 BU165076 AI753664 AA447170 BM839864 AI214195 AI361130 
    BM015731 BQ101165 BM739889 BG033093 AK000601 NM_014180 AI138489 BE326337 
    AK097880 BE878577 BX114909 AW404374 BQ221495 BM844574 BQ100863 CK823152 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for MRPL22    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7a · 7b · 7c · 7d
    SP1:              -                 -                                             
    SP2:              -           -     -                                             
    SP3:                                -                                             
    SP4:                          -     -                                             
    SP5:                                                                              


    ECgene alternative splicing isoforms for MRPL22

    Expression
    for MRPL22 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    MRPL22 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CCAAAGAGTA
    MRPL22 Expression
    About this image

    MRPL22 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table

    Stem Cell Differentiation: 1 LifeMap Cell 
    NameCategory
    Definitive endoderm-like cells (A scalable, suspensi...)
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See MRPL22 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for MRPL22

    SOURCE GeneReport for Unigene cluster: Hs.483924
        SABiosciences Custom PCR Arrays for MRPL22
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    In Situ
    Assay Products:     
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    Orthologs
    for MRPL22 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for MRPL22 gene from 7/21 species (see all 21)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Mrpl221 , 5 mitochondrial ribosomal protein L221, 5 85.76(n)1
    89.32(a)1    		   11 (35.89 cM)5
    2167671  NM_175001.31  NP_778166.21 
     581716615 
    chicken
    (Gallus gallus)    		 Aves MRPL221 mitochondrial ribosomal protein L22 72.25(n)
    75.63(a)    		   416253  XM_414573.3  XP_414573.1 
    lizard
    (Anolis carolinensis)    		 Reptilia MRPL226
    		 --
    		 73(a)
    		 1 ↔ 1
    		 GL343205.1(880990-896751)
    tropical clawed frog
    (Xenopus tropicalis)    		 Amphibia Str.174242 Transcribed sequence with moderate similarity to protein more 78.13(n)    BX755661.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii Dr.139822 Transcribed sequence with moderate similarity to protein more 75.7(n)    CK396410.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta mRpL221 mitochondrial ribosomal protein L22 55.31(n)
    50.84(a)    		   32662  NM_078655.3  NP_523379.2 
    worm
    (Caenorhabditis elegans)    		 Secernentea mrpl-221 Protein MRPL-22 45.06(n)
    32.1(a)    		   176482  NM_066939.3  NP_499340.1 


    ENSEMBL Gene Tree for MRPL22 (if available)
    TreeFam Gene Tree for MRPL22 (if available) 

    Paralogs
    for MRPL22 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for MRPL22 gene

    MRPL22 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for MRPL22
    PGOHUM00000245538


    Genomic Variants
    for MRPL22 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/449 NCBI SNPs in MRPL22 are shown (see all 449)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 5 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs792512341,2
    		F--154319810(+) ATGCCT/CTGTTG 2 -- us2k11Minor allele frequency- C:0.04EA 120
    rs1852577711,2
    		--154319834(+) AATAAA/GTGAGA 2 -- us2k10--------
    rs3487501,2
    		C,F,A,H--154319892(+) ATAAAT/CTCATT 2 -- us2k1 tfbs323Minor allele frequency- C:0.21NS EA NA WA CSA 2352
    rs1135026751,2
    		--154320006(+) CTAATC/TCTAGC 2 -- us2k11Minor allele frequency- T:0.50CSA 2
    rs1899122491,2
    		--154320056(+) GAATTC/TGAGAT 2 -- us2k10--------
    rs1443947461,2
    		--154320322(+) CCTAAA/GGTTAG 2 -- us2k10--------
    rs777683611,2
    		F--154320404(+) TTCTAG/CTTTGT 2 -- us2k11Minor allele frequency- C:0.03EA 120
    rs1811815931,2
    		--154320407(+) TAGTTC/TGTGAG 2 -- us2k10--------
    rs738072091,2
    		C--154320570(+) TAAGTA/GCTGCT 2 -- us2k12Minor allele frequency- G:0.05WA 120
    rs283726881,2
    		C,F--154320596(+) CAGGAA/GATCCA 2 -- us2k18Minor allele frequency- G:0.09MN EA NA WA EU 2180

    HapMap Linkage Disequilibrium report for MRPL22 (154320630 - 154348971 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for MRPL22: --

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MRPL22
    DNA2.0 Custom Variant and Variant Library Synthesis for MRPL22

    Disorders / Diseases
    for MRPL22 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    MRPL22 for disorders           About GeneDecksing

    OMIM gene information: 611835    OMIM disorders: --

    1 disease for MRPL22:    About MalaCards
    genetic disease

    Human Genome Epidemiology (HuGE) Navigator: MRPL22 (2 documents)

    Export disorders for MRPL22 gene to outside databases

    Publications
    for MRPL22 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for MRPL22 gene, integrated from 9 sources (see all 22):
    (articles sorted by number of sources associating them with MRPL22)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    3. The human mitochondrial ribosomal protein genes: mapping of 54 genes to the chromosomes and implications for human disorders. (PubMed id 11543634)1, 2 Kenmochi N....Tanaka T. (2001)
    4. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)1, 2 Zhang Q.-H.... Chen Z. (2000)
    5. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    6. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    7. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    8. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    9. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    10. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)

    External Searches for MRPL22 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Genome Databases showing MRPL22 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 29093 HGNC: 14480 AceView: MRPL22 Ensembl:ENSG00000082515 euGenes: HUgn29093
    ECgene: MRPL22 H-InvDB: MRPL22

    Other Databases showing MRPL22 gene

    (According to HUGE)
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    Specialized Databases showing MRPL22 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for MRPL22 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for MRPL22 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for MRPL22 gene:
    Search GeneIP for patents involving MRPL22

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