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MRPL2 Gene

protein-coding   GIFtS: 55
GCID: GC06M043021

Mitochondrial Ribosomal Protein L2

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Mitochondrial Ribosomal Protein L21 2
L2mt2 3
MRP-L22 3
39S Ribosomal Protein L2, Mitochondrial2
MRP-L142
RPML142

External Ids:    HGNC: 140561   Entrez Gene: 510692   Ensembl: ENSG000001126517   OMIM: 6118225   UniProtKB: Q5T6533   

Export aliases for MRPL2 gene to outside databases

Previous GC identifers: GC06M043023 GC06M043068 GC06M043129 GC06M042738


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for MRPL2 Gene:
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the
mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit.
They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is
reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain
a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and
sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a
39S subunit protein that belongs to the EcoL2 ribosomal protein family. A pseudogene corresponding to this gene
is found on chromosome 12q. (provided by RefSeq, Jul 2008)

GeneCards Summary for MRPL2 Gene:
MRPL2 (mitochondrial ribosomal protein L2) is a protein-coding gene. Diseases associated with MRPL2 include pneumonia, and tuberculosis. GO annotations related to this gene include structural constituent of ribosome.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000006.12  NT_007592.16  NC_018917.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the MRPL2 gene promoter:
         GR   E2F-4   E2F-3a   E2F-5   Sox5   Bach2   E2F-2   E2F   E2F-1   GR-alpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMRPL2 promoter sequence
   Search Chromatin IP Primers for MRPL2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MRPL2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p21.3   Ensembl cytogenetic band:  6p21.1   HGNC cytogenetic band: 6p21.3

MRPL2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MRPL2 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06M043021:  view genomic region     (about GC identifiers)

Start:
43,021,767 bp from pter      End:
43,027,544 bp from pter
Size:
5,778 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: RM02_HUMAN, Q5T653 (See protein sequence)
Recommended Name: 39S ribosomal protein L2, mitochondrial precursor  
Size: 305 amino acids; 33301 Da
Sequence caution: Sequence=AAD27731.1; Type=Frameshift; Positions=274, 283; Sequence=CAI13780.1; Type=Erroneous
gene model prediction;
Secondary accessions: B2RC56 Q8WUL1 Q96Q56 Q9Y311

Explore the universe of human proteins at neXtProt for MRPL2: NX_Q5T653

Explore proteomics data for MRPL2 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See MRPL2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_057034.2  
    ENSEMBL proteins: 
     ENSP00000373404   ENSP00000230413   ENSP00000419753   ENSP00000417101   ENSP00000419710  

    MRPL2 Human Recombinant Protein Products:

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    Novus Biologicals MRPL2 Lysates
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    MRPL2 Antibody Products:

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    Abcam antibodies for MRPL2
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    LSBio Antibodies in human, mouse, rat for MRPL2

    MRPL2 Assay Products:

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    Cloud-Clone Corp. ELISAs for MRPL2
    Cloud-Clone Corp. CLIAs for MRPL2


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    MRPL: Mitochondrial ribosomal proteins / large subunits

    Selected InterPro protein domains (see all 7):
     IPR002171 Ribosomal_L2
     IPR008991 Translation_prot_SH3-like
     IPR022666 Rbsml_prot_L2_RNA-bd_dom
     IPR014726 Ribosomal_L2_dom3
     IPR012340 NA-bd_OB-fold

    Graphical View of Domain Structure for InterPro Entry Q5T653

    ProtoNet protein and cluster: Q5T653

    UniProtKB/Swiss-Prot: RM02_HUMAN, Q5T653
    Similarity: Belongs to the ribosomal protein L2P family


    MRPL2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003735structural constituent of ribosome IEA--
    GO:0044822poly(A) RNA binding IDA--
         
    MRPL2 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for MRPL2
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for MRPL2

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for MRPL2
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for MRPL2

    miRNA
    Products:
        
    miRTarBase miRNAs that target MRPL2:
    hsa-mir-92a-3p (MIRT049770), hsa-mir-107 (MIRT048287)

    Block miRNA regulation of human, mouse, rat MRPL2 using miScript Target Protectors
    2 qRT-PCR Assays for microRNAs that regulate MRPL2:
    hsa-miR-802 hsa-miR-885-5p
    SwitchGear 3'UTR luciferase reporter plasmidMRPL2 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for MRPL2
    Predesigned siRNA for gene silencing in human, mouse, rat MRPL2

    Gene Editing
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    DNA2.0 Custom Protein Engineering Service for MRPL2

    Clone
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    OriGene clones in human, mouse for MRPL2 (see all 8)
    OriGene ORF clones in mouse, rat for MRPL2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: MRPL2 (NM_021134)
    Sino Biological Human cDNA Clone for MRPL2
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MRPL2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MRPL2

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for MRPL2 
    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MRPL2


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    RM02_HUMAN, Q5T653: Mitochondrion (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    mitochondrion3
    cytosol2
    peroxisome2

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005739mitochondrion IEA--
    GO:0005840ribosome IEA--

    MRPL2 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for MRPL2 About    
    See pathways by source

    SuperPathContained pathways About
    1CFTR translational fidelity class I mutations
    Ribosome0.54

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways




    1 Kegg Pathway  (Kegg details for MRPL2):
        Ribosome


    MRPL2 for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for MRPL2
    Interactions:

        Search GeneGlobe Interaction Network for MRPL2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for MRPL2 (Q5T6532, 3 ENSP000003734044) via UniProtKB, MINT, STRING, and/or I2D (see all 590)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HIST1H4AP628053I2D: score=1 
    HIST1H4BP628053I2D: score=1 
    HIST1H4CP628053I2D: score=1 
    HIST1H4DP628053I2D: score=1 
    HIST1H4EP628053I2D: score=1 
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006412translation IEA--

    MRPL2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for MRPL2 (RM02)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for MRPL2 gene: 
    NM_015950.3  

    Unigene Cluster for MRPL2:

    Mitochondrial ribosomal protein L2
    Hs.55041  [show with all ESTs]
    Unigene Representative Sequence: NM_015950
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000388752(uc003ots.1) ENST00000485654 ENST00000230413 ENST00000489623
    ENST00000470667 ENST00000491898(uc011dvc.2) ENST00000480286 ENST00000487429(uc010jyi.3 uc003ott.4)
    ENST00000468957
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat MRPL2 using miScript Target Protectors
    2 qRT-PCR Assays for microRNAs that regulate MRPL2:
    hsa-miR-802 hsa-miR-885-5p
    SwitchGear 3'UTR luciferase reporter plasmidMRPL2 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for MRPL2
    Predesigned siRNA for gene silencing in human, mouse, rat MRPL2
    Clone
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    OriGene clones in human, mouse for MRPL2 (see all 8)
    OriGene ORF clones in mouse, rat for MRPL2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: MRPL2 (NM_021134)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MRPL2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MRPL2
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for MRPL2
    OriGene qSTAR qPCR primer pairs in human, mouse for MRPL2
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat MRPL2
      QuantiTect SYBR Green Assays in human, mouse, rat MRPL2
      QuantiFast Probe-based Assays in human, mouse, rat MRPL2

    Additional mRNA sequence: 

    AF086160.1 AF132956.1 AK301041.1 AK307208.1 AK314948.1 BC013685.1 BC020212.1 

    12 DOTS entries:

    DT.100783352  DT.101972501  DT.314883  DT.121374918  DT.75101705  DT.121374949  DT.102836930  DT.100783351 
    DT.121374938  DT.121374922  DT.95159384  DT.97819493 

    Selected AceView cDNA sequences (see all 156):

    BM474838 AI028306 BQ939927 BM313091 BQ681996 BC013685 BQ223798 BM458798 
    AI283794 NM_015950 AW160610 BM553982 AF086160 AI185677 CA454108 AI342982 
    CA311296 BU192466 CB139607 BM787277 AI499025 CF128671 BQ431890 AI701608 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for MRPL2 (see all 7)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b · 3c ^ 4 ^ 5a · 5b ^ 6a · 6b ^ 7 ^ 8a · 8b · 8c
    SP1:                          -           -     -                             -                           
    SP2:                          -           -     -                             -     -                     
    SP3:                          -           -     -                                                         
    SP4:                          -           -     -                                                         
    SP5:                          -           -     -     -     -     -     -     -     -                     


    ECgene alternative splicing isoforms for MRPL2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    MRPL2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AAGAGTTACG
    MRPL2 Expression
    About this image


    MRPL2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     
     Inner Cell Mass (Early Embryonic Tissues)
             Inner Cell Mass Cells Inner Cell Mass
    MRPL2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    MRPL2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.55041
        Custom PCR Arrays for MRPL2
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for MRPL2
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    QuantiFast Probe-based Assays in human, mouse, rat MRPL2
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MRPL2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for MRPL2 gene from Selected species (see all 17)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Mrpl21 , 5 mitochondrial ribosomal protein L21, 5 85.14(n)1
    84.26(a)1
      17 (22.90 cM)5
    273981  NM_025302.31  NP_079578.11 
     466462295 
    chicken
    (Gallus gallus)
    Aves MRPL21 mitochondrial ribosomal protein L2 73.36(n)
    82.91(a)
      421256  XM_419327.3  XP_419327.3 
    lizard
    (Anolis carolinensis)
    Reptilia MRPL26
    mitochondrial ribosomal protein L2
    70(a)
    1 ↔ 1
    2(144194598-144206546)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.210752 Xenopus laevis transcribed sequence with weak similarity more 77.57(n)    CF547869.1 
    zebrafish
    (Danio rerio)
    Actinopterygii im:69082241 im:6908224 67.3(n)
    74.14(a)
      571648  XM_005173045.1  XP_005173102.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta mRpL21 , 3 protein biosynthesis structural
    constituent of more3
    mitochondrial ribosomal protein L21
    50(a)3
    56.86(n)1
    52.04(a)1
      68A73
    392531  NM_079298.41  NP_524022.11 
    worm
    (Caenorhabditis elegans)
    Secernentea mrpl-21 mrpl-2 50.57(n)
    41.03(a)
      176903  NM_067586.3  NP_499987.2 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes RML26
    Mitochondrial ribosomal protein of the large subun...
    22(a)
    1 ↔ 1
    V(59670-60851) YEL050C


    ENSEMBL Gene Tree for MRPL2 (if available)
    TreeFam Gene Tree for MRPL2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for MRPL2 gene

    MRPL2 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for MRPL2
    PGOHUM00000239886


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for MRPL2 (see all 52)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1457437971,2
    C--43023708(+) GGCAGA/GGCCCC 2 A syn10--------
    rs1465449121,2
    C,F--43023723(+) GGATGC/TGCATC 2 A syn11Minor allele frequency- T:0.00NA 4536
    rs1451457761,2
    C,F--43023731(+) ATCCCC/TTTCCC 2 R G mis12Minor allele frequency- T:0.00NA EU 5865
    rs2004983531,2
    --43023850(+) TTCAAC/GATTGT 2 I M mis10--------
    rs1995694011,2
    --43023859(+) GTATCC/TCCAGC 2 G syn10--------
    rs1409537551,2
    C--43023869(+) CCTGCA/GTGTTT 2 T M mis10--------
    rs2014017591,2
    --43023878(+) TTTCTA/GTGGCG 2 T I mis10--------
    rs1503712961,2
    C--43023879(+) TTCTGC/TGGCGA 2 T A mis10--------
    rs1995924871,2
    --43023918(+) AACCAC/GAGCTA 2 L V mis10--------
    rs2020468781,2
    --43023946(+) AGGGTA/GAGGGA 1 -- int10--------

    HapMap Linkage Disequilibrium report for MRPL2 (43021767 - 43027544 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for MRPL2:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv462930CNV Loss19166990
    nsv462927CNV Loss19166990

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing MRPL2
    DNA2.0 Custom Variant and Variant Library Synthesis for MRPL2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 611822    OMIM disorders: --

    3 diseases for MRPL2:    
    About MalaCards
    pneumonia    tuberculosis    malaria


    MRPL2 for disorders           About GeneDecksing

    Genetic Association Database (GAD): MRPL2
    Human Genome Epidemiology (HuGE) Navigator: MRPL2 (1 document)

    Export disorders for MRPL2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for MRPL2 gene, integrated from 10 sources (see all 18):
    (articles sorted by number of sources associating them with MRPL2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (PLoS ONE 2010)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (Nature 2003)
    4. The human mitochondrial ribosomal protein genes: mapping of 54 genes to the chromosomes and implications for human disorders. (PubMed id 11543634)1, 2 Kenmochi N.... Tanaka T. (Genomics 2001)
    5. Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics. (PubMed id 10810093)1, 2 Lai C.-H.... Lin W.-C. (Genome Res. 2000)
    6. Mammalian mitochondrial ribosomal proteins (2). Amino acid sequencing, characterization, and identification of corresponding gene sequences. (PubMed id 10593885)1, 9 O'Brien T.W.... Graack H.R. (J. Biol. Chem. 1999)
    7. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    8. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    9. Toward an understanding of the protein interaction network of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (Mol. Syst. Biol. 2011)
    10. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 51069 HGNC: 14056 AceView: MRPL2 Ensembl:ENSG00000112651 euGenes: HUgn51069
    ECgene: MRPL2 Kegg: 51069 H-InvDB: MRPL2

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for MRPL2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for MRPL2 gene:
    Search GeneIP for patents involving MRPL2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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