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MRPL13 Gene

protein-coding   GIFtS: 58
GCID: GC08M121393

Mitochondrial Ribosomal Protein L13

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Mitochondrial Ribosomal Protein L131 2     L132
L13mt2 3     L13A2
MRP-L132 3     RPL132
39S Ribosomal Protein L13, Mitochondrial2     RPML132

External Ids:    HGNC: 142781   Entrez Gene: 289982   Ensembl: ENSG000001721727   OMIM: 6102005   UniProtKB: Q9BYD13   

Export aliases for MRPL13 gene to outside databases

Previous GC identifers: GC08M120377 GC08M121466 GC08M121076 GC08M121364 GC08M121477 GC08M116728


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for MRPL13 Gene:
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the
mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit.
They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is
reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain
a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and
sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a
39S subunit protein. (provided by RefSeq, Jul 2008)

GeneCards Summary for MRPL13 Gene:
MRPL13 (mitochondrial ribosomal protein L13) is a protein-coding gene. Diseases associated with MRPL13 include ulcerative proctitis, and epidural abscess. GO annotations related to this gene include structural constituent of ribosome.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000008.11  NT_008046.17  NC_018919.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the MRPL13 gene promoter:
         Spz1   p53   Nkx2-5   FOXL1   NF-AT   NF-AT4   NF-AT2   STAT3   NF-AT3   NF-AT1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMRPL13 promoter sequence
   Search Chromatin IP Primers for MRPL13

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MRPL13


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 8q22.1-q22.3   Ensembl cytogenetic band:  8q24.12   HGNC cytogenetic band: 8q22.1-q22.3

MRPL13 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MRPL13 gene location

GeneLoc information about chromosome 8         GeneLoc Exon Structure

GeneLoc location for GC08M121393:  view genomic region     (about GC identifiers)

Start:
121,393,000 bp from pter      End:
121,457,647 bp from pter
Size:
64,648 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: RM13_HUMAN, Q9BYD1 (See protein sequence)
Recommended Name: 39S ribosomal protein L13, mitochondrial  
Size: 178 amino acids; 20692 Da
Subunit: Interacts with OXA1L (By similarity)
Sequence caution: Sequence=AAF17202.1; Type=Frameshift; Positions=160;
Secondary accessions: B2R4R8 Q9UI04

Explore the universe of human proteins at neXtProt for MRPL13: NX_Q9BYD1

Explore proteomics data for MRPL13 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys114
  • Modification sites at PhosphoSitePlus

  • See MRPL13 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_054797.2  
    ENSEMBL proteins: 
     ENSP00000428229   ENSP00000428867   ENSP00000306548   ENSP00000430545  

    MRPL13 Human Recombinant Protein Products:

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    MRPL13 Assay Products:

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    Cloud-Clone Corp. ELISAs for MRPL13
    Cloud-Clone Corp. CLIAs for MRPL13


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    MRPL: Mitochondrial ribosomal proteins / large subunits

    4 InterPro protein domains:
     IPR023563 Ribosomal_L13_CS
     IPR005823 Ribosomal_L13_bac-type
     IPR005822 Ribosomal_L13
     IPR023564 Ribosomal_L13_dom

    Graphical View of Domain Structure for InterPro Entry Q9BYD1

    ProtoNet protein and cluster: Q9BYD1

    1 Blocks protein domain: IPB005822 Ribosomal protein L13

    UniProtKB/Swiss-Prot: RM13_HUMAN, Q9BYD1
    Similarity: Belongs to the ribosomal protein L13P family


    MRPL13 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003735structural constituent of ribosome NAS11279069
    GO:0005515protein binding IPI--
    GO:0044822poly(A) RNA binding IDA--
         
    MRPL13 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for MRPL13:
     Decreased viability of wild-ty  Increased cell number in G2M,  

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for MRPL13
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for MRPL13
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for MRPL13

    miRNA
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    miRTarBase miRNAs that target MRPL13:
    hsa-mir-20a-5p (MIRT050566), hsa-mir-215-5p (MIRT024315), hsa-mir-192-5p (MIRT026575)

    Block miRNA regulation of human, mouse, rat MRPL13 using miScript Target Protectors
    1 qRT-PCR Assays for microRNA that regulate MRPL13:
    hsa-miR-3163
    SwitchGear 3'UTR luciferase reporter plasmidMRPL13 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for MRPL13
    Predesigned siRNA for gene silencing in human, mouse, rat MRPL13

    Gene Editing
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MRPL13


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    RM13_HUMAN, Q9BYD1: Mitochondrion
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    mitochondrion5
    nucleus3
    cytosol1

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion ----
    GO:0005761mitochondrial ribosome IDA--
    GO:0005762mitochondrial large ribosomal subunit NAS11279069
    GO:0005840ribosome ----

    MRPL13 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for MRPL13 About    
    See pathways by source

    SuperPathContained pathways About
    1CFTR translational fidelity class I mutations
    Ribosome0.54

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    1 Kegg Pathway  (Kegg details for MRPL13):
        Ribosome


    MRPL13 for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for MRPL13
    Interactions:

        Search GeneGlobe Interaction Network for MRPL13

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for MRPL13 (Q9BYD12, 3 ENSP000003065484) via UniProtKB, MINT, STRING, and/or I2D (see all 432)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ICT1Q141972, 3, ENSP000003015854MINT-8079030 I2D: score=1 STRING: ENSP00000301585
    MRPL3P090012, 3, ENSP000002649954MINT-8079030 I2D: score=1 STRING: ENSP00000264995
    OXA1LQ150703, ENSP000002858484I2D: score=1 STRING: ENSP00000285848
    MRPL16Q9NX202, ENSP000003001514MINT-8079030 STRING: ENSP00000300151
    MRPL19P494062, ENSP000003774864MINT-8079030 STRING: ENSP00000377486
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006412translation NAS11279069

    MRPL13 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for MRPL13 (RM13)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for MRPL13 gene: 
    NM_014078.5  

    Unigene Cluster for MRPL13:

    Mitochondrial ribosomal protein L13
    Hs.333823  [show with all ESTs]
    Unigene Representative Sequence: AK123239
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000521648 ENST00000518696(uc010mdf.3) ENST00000522717 ENST00000306185(uc003ypa.3)
    ENST00000523316 ENST00000518918 ENST00000520677
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat MRPL13 using miScript Target Protectors
    1 qRT-PCR Assays for microRNA that regulate MRPL13:
    hsa-miR-3163
    SwitchGear 3'UTR luciferase reporter plasmidMRPL13 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for MRPL13
    Predesigned siRNA for gene silencing in human, mouse, rat MRPL13
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    GenScript: all cDNA clones in your preferred vector: MRPL13 (NM_014078)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MRPL13
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MRPL13
    Primer
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    OriGene qPCR primer pairs and template standards for MRPL13
    OriGene qSTAR qPCR primer pairs in human, mouse for MRPL13
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat MRPL13
      QuantiTect SYBR Green Assays in human, mouse, rat MRPL13
      QuantiFast Probe-based Assays in human, mouse, rat MRPL13

    Additional mRNA sequence: 

    AB049640.1 AF112214.1 AK123239.1 AK307322.1 AK311924.1 BC009190.2 BC021744.2 

    17 DOTS entries:

    DT.453475  DT.100792938  DT.121480769  DT.121480683  DT.100792944  DT.100792933  DT.91674190  DT.100676479 
    DT.121480611  DT.86846927  DT.91756319  DT.102828645  DT.91756316  DT.95164137  DT.99966358  DT.40112214 
    DT.95164139 

    Selected AceView cDNA sequences (see all 323):

    BM695769 BQ681081 CA441069 AA433943 BG182029 AA291501 AV706885 BM791153 
    AA706862 BP429421 BM789873 BM726251 BU685630 CB134198 AV764443 AA461447 
    AA430750 BE900419 BG196069 BQ478287 CA429224 CA426511 AA917918 AA313840 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for MRPL13    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7
    SP1:                                      -               
    SP2:                    -                                 


    ECgene alternative splicing isoforms for MRPL13

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    MRPL13 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTGCCAAAAA
    MRPL13 Expression
    About this image

    MRPL13 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    MRPL13 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.333823
        Custom PCR Arrays for MRPL13
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MRPL13

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for MRPL13 gene from Selected species (see all 24)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Mrpl131 , 5 mitochondrial ribosomal protein L131, 5 87.08(n)1
    89.33(a)1
      15 (22.02 cM)5
    685371  NM_026759.31  NP_081035.11 
     555340945 
    chicken
    (Gallus gallus)
    Aves MRPL131 mitochondrial ribosomal protein L13 73.97(n)
    77.53(a)
      420356  NM_001277471.1  NP_001264400.1 
    lizard
    (Anolis carolinensis)
    Reptilia MRPL136
    mitochondrial ribosomal protein L13
    67(a)
    1 ↔ 1
    GL343269.1(1398100-1428053)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.331712 Xenopus laevis transcribed sequence with moderate similarity more 74.11(n)    BM929033.1 
    zebrafish
    (Danio rerio)
    Actinopterygii mrpl131 mitochondrial ribosomal protein L13 70.22(n)
    77.53(a)
      553555  NM_001020534.1  NP_001018370.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta mRpL131 , 3 protein biosynthesis structural
    constituent of more3
    mitochondrial ribosomal protein L131
    47(a)3
    51.14(n)1
    47.16(a)1
      37B13
    351451  NM_078874.31  NP_523598.21 
    worm
    (Caenorhabditis elegans)
    Secernentea mrpl-131 mrpl-13 52.78(n)
    39.88(a)
      172479  NM_059666.5  NP_492067.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes MRPL23(YOR150W)4
    MRPL231
    Mitochondrial ribosomal protein of the large subunit4
    MRPL231
    47.32(n)1
    39.16(a)1
      15(611999-612490)4
    8543211, 4  NP_014793.11, 4 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons emb14731 emb1473 48.95(n)
    34.23(a)
      844199  NM_106510.2  NP_177984.1 
    rice
    (Oryza sativa)
    Liliopsida Os01g07492001 Os01g0749200 51.44(n)
    33.07(a)
      4325555  NM_001050781.1  NP_001044246.1 


    ENSEMBL Gene Tree for MRPL13 (if available)
    TreeFam Gene Tree for MRPL13 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for MRPL13 (see all 805)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 8 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1496883411,2
    --121407771(+) TCTAAC/TGAGCA 1 -- ds50010--------
    rs125440601,2
    C,F,A,H--121407824(+) CTATAT/AGGGAC 1 -- ds500113Minor allele frequency- A:0.45NS EA NA CSA WA 774
    rs1454942111,2
    --121408135(+) ATCAGA/GTTACA 1 -- ut310--------
    rs1403006661,2
    --121408174(+) AATTAC/TAATTT 1 -- ut310--------
    rs1178185751,2
    C,F--121408187(+) TATTGA/GAGGAC 1 -- ut311Minor allele frequency- G:0.02NA 120
    rs66501,2
    C,F,A,H--121408195(+) GACTAC/TACCTT 1 -- ut3125Minor allele frequency- N:0.00EA NA NS CSA WA 2554
    rs2008301891,2
    --121408371(+) GAAAG-/AAAAAA 1 -- int10--------
    rs2016736191,2
    C--121408395(+) TTCATG/TAATCA 1 -- int11Minor allele frequency- T:0.00EU 1025
    rs3730712281,2
    C--121408427(+) GATGAA/GATTAT 1 -- int10--------
    rs1807218931,2
    C--121408439(+) TTTTCC/GAATTT 1 -- int10--------

    HapMap Linkage Disequilibrium report for MRPL13 (121393000 - 121457647 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for MRPL13:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv996748CNV Deletion20482838
    nsv470235CNV Loss18288195
    dgv7872n71CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing MRPL13
    DNA2.0 Custom Variant and Variant Library Synthesis for MRPL13

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 610200    OMIM disorders: --

    8 diseases for MRPL13:    
    About MalaCards
    ulcerative proctitis    epidural abscess    spondylolysis    lymphogranuloma venereum
    proctitis    pneumonia    tuberculosis    malaria


    MRPL13 for disorders           About GeneDecksing

    Genetic Association Database (GAD): MRPL13
    Human Genome Epidemiology (HuGE) Navigator: MRPL13 (1 document)

    Export disorders for MRPL13 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for MRPL13 gene, integrated from 10 sources (see all 25):
    (articles sorted by number of sources associating them with MRPL13)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (PLoS ONE 2010)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Structural compensation for the deficit of rRNA with proteins in the mammalian mitochondrial ribosome. Systematic analysis of protein components of the large ribosomal subunit from mammalian mitochondria. (PubMed id 11279069)1, 2 Suzuki T....Watanabe K. (J. Biol. Chem. 2001)
    4. The human mitochondrial ribosomal protein genes: mapping of 54 genes to the chromosomes and implications for human disorders. (PubMed id 11543634)1, 3 Kenmochi N.... Tanaka T. (Genomics 2001)
    5. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    6. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    7. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    8. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    9. Properties of the C-terminal tail of human mitochondrial inner membrane protein Oxa1L and its interactions with mammalian mitochondrial ribosomes. (PubMed id 20601428)1 Haque M.E....Spremulli L.L. (J. Biol. Chem. 2010)
    10. A functional peptidyl-tRNA hydrolase, ICT1, has been recruited into the human mitochondrial ribosome. (PubMed id 20186120)1 Richter R....Chrzanowska-Lightowlers Z.M. (EMBO J. 2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 28998 HGNC: 14278 AceView: MRPL13 Ensembl:ENSG00000172172 euGenes: HUgn28998
    ECgene: MRPL13 Kegg: 28998 H-InvDB: MRPL13

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for MRPL13 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for MRPL13 gene:
    Search GeneIP for patents involving MRPL13

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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