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MRPL12 Gene

protein-coding   GIFtS: 57
GCID: GC17P079670

Mitochondrial Ribosomal Protein L12


(Previous symbol: RPML12)
  Search for MRPL12
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Mitochondrial Ribosomal Protein L121 2     39S Ribosomal Protein L12, Mitochondrial2
RPML121 2 3 5     MRP-L31/342
5c5-22 3     MRPL72
L12mt2 3     MRPL7/L122
MRP-L122 3     

External Ids:    HGNC: 103781   Entrez Gene: 61822   Ensembl: ENSG000002628147   OMIM: 6023755   UniProtKB: P528153   

Export aliases for MRPL12 gene to outside databases

Previous GC identifers: GC17U990085 GC17P080228 GC17P080366 GC17P077280 GC17P075116


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for MRPL12 Gene:
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the
mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit.
They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is
reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain
a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and
sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a
39S subunit protein which forms homodimers. In prokaryotic ribosomes, two L7/L12 dimers and one L10 protein form
the L8 protein complex. (provided by RefSeq, Jul 2008)

GeneCards Summary for MRPL12 Gene:
MRPL12 (mitochondrial ribosomal protein L12) is a protein-coding gene. GO annotations related to this gene include structural constituent of ribosome and RNA binding.

Gene Wiki entry for MRPL12 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000017.10  NC_018928.2  NT_010783.16  
Regulatory elements:
   Regulatory transcription factor binding sites in the MRPL12 gene promoter:
         USF1   AML1a   NRSF form 1   Lmo2   AP-4   NRSF form 2   Roaz   HEN1   USF-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMRPL12 promoter sequence
   Search Chromatin IP Primers for MRPL12

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MRPL12


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q25   Ensembl cytogenetic band:  17q25.3   HGNC cytogenetic band: 17q25

MRPL12 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MRPL12 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17P079670:  view genomic region     (about GC identifiers)

Start:
79,670,387 bp from pter      End:
79,674,556 bp from pter
Size:
4,170 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: RM12_HUMAN, P52815 (See protein sequence)
Recommended Name: 39S ribosomal protein L12, mitochondrial precursor  
Size: 198 amino acids; 21348 Da
Subunit: Interacts with NOA1
Sequence caution: Sequence=AAD16894.1; Type=Frameshift; Positions=Several;
Secondary accessions: Q969U0 Q9HCA2 Q9UQJ3

Explore the universe of human proteins at neXtProt for MRPL12: NX_P52815

Explore proteomics data for MRPL12 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See MRPL12 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_002940.2  
    ENSEMBL proteins: 
     ENSP00000333837  

    MRPL12 Human Recombinant Protein Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    MRPL: Mitochondrial ribosomal proteins / large subunits

    4 InterPro protein domains:
     IPR013823 Ribosomal_L7/L12_C
     IPR000206 Ribosomal_L7/12
     IPR014719 Ribosomal_L7/12_C/ClpS-like
     IPR008932 Ribosomal_L7/L12_oligo

    Graphical View of Domain Structure for InterPro Entry P52815

    ProtoNet protein and cluster: P52815

    1 Blocks protein domain: IPB000206 Ribosomal protein L7/L12

    UniProtKB/Swiss-Prot: RM12_HUMAN, P52815
    Similarity: Belongs to the ribosomal protein L7/L12P family


    Find genes that share domains with MRPL12           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003723RNA binding TAS8626705
    GO:0003735structural constituent of ribosome IEA--
    GO:0005515protein binding IPI17337445
         
    Find genes that share ontologies with MRPL12           About GenesLikeMe


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for MRPL12
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    miRNA
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    miRTarBase miRNAs that target MRPL12:
    hsa-mir-98-5p (MIRT027400), hsa-mir-107 (MIRT048289), hsa-mir-423-3p (MIRT042624), hsa-mir-16-5p (MIRT031389), hsa-mir-340-3p (MIRT043855)

    Block miRNA regulation of human, mouse, rat MRPL12 using miScript Target Protectors
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    RM12_HUMAN, P52815: Mitochondrion
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    mitochondrion5

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005739mitochondrion IDA17337445
    GO:0005762mitochondrial large ribosomal subunit IDA--
    GO:0005840ribosome ----

    Find genes that share ontologies with MRPL12           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for MRPL12 About    
    See pathways by source

    SuperPathContained pathways About
    1CFTR translational fidelity class I mutations
    Ribosome0.54


    Find genes that share SuperPaths with MRPL12           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways




    1 Kegg Pathway  (Kegg details for MRPL12):
        Ribosome

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for MRPL12
    Interactions:

        GeneGlobe Interaction Network for MRPL12

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for MRPL12 (P528152, 3 ENSP000003338374) via UniProtKB, MINT, STRING, and/or I2D (see all 298)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TMEM51Q9NW972, 3MINT-63866 I2D: score=4 
    ICT1Q141972, 3, ENSP000003015854MINT-8079030 MINT-8079734 I2D: score=1 STRING: ENSP00000301585
    PPP2R2BQ000053, ENSP000003365914I2D: score=1 STRING: ENSP00000336591
    SRRM2Q9UQ353, ENSP000003017404I2D: score=1 STRING: ENSP00000301740
    MRPL19P494062, ENSP000003774864MINT-8079030 STRING: ENSP00000377486
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006390transcription from mitochondrial promoter IDA17337445
    GO:0006412translation IEA--
    GO:0045893positive regulation of transcription, DNA-templated IDA17337445

    Find genes that share ontologies with MRPL12           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for MRPL12 (RM12)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for MRPL12 gene: 
    NM_002949.3  

    Unigene Cluster for MRPL12:

    Mitochondrial ribosomal protein L12
    Hs.109059  [show with all ESTs]
    Unigene Representative Sequence: BM557512
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000333676(uc002kbh.2)
    miRNA
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      QuantiFast Probe-based Assays in human, mouse, rat MRPL12

    Additional mRNA sequence: 

    AF105278.1 BC002344.2 BC007497.2 EF036488.1 U25041.1 X79865.1 

    6 DOTS entries:

    DT.99957736  DT.116243  DT.95194105  DT.92469503  DT.92469583  DT.92469591 

    Selected AceView cDNA sequences (see all 715):

    BM556222 AI807809 CA442381 BG287685 AI499854 BI819266 CK903781 AW001566 
    CA307884 CD672179 BQ927283 BM810888 BU556920 AI888921 BM544364 BQ878046 
    AL045907 BI083963 AJ711155 AI201897 BQ425577 BC003565 BQ884011 NM_002949 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    MRPL12 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGTCTGTGCC
    MRPL12 Expression
    About this image

    MRPL12 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    MRPL12 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.109059
        Custom PCR Arrays for MRPL12
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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for MRPL12 gene from Selected species (see all 20)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Mrpl121 , 5 mitochondrial ribosomal protein L121, 5 83.67(n)1
    84.85(a)1
      11 (84.18 cM)5
    562821  NM_027204.21  NP_081480.21 
     1204846135 
    chicken
    (Gallus gallus)
    Aves MRPL121 mitochondrial ribosomal protein L12 70.78(n)
    69.14(a)
      769031  XM_001232213.3  XP_001232214.2 
    lizard
    (Anolis carolinensis)
    Reptilia MRPL126
    mitochondrial ribosomal protein L12
    57(a)
    1 ↔ 1
    2(118783577-118791167)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.240662 Xenopus laevis transcribed sequence with weak similarity more 71.15(n)    CB200702.2 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.98052 Transcribed sequence with weak similarity to protein more 75.43(n)    CK362812.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta mRpL121 mitochondrial ribosomal protein L12 54.64(n)
    39.85(a)
      44326  NM_080003.4  NP_524742.1 
    worm
    (Caenorhabditis elegans)
    Secernentea mrpl-121 mrpl-12 52.17(n)
    45.65(a)
      176495  NM_066959.5  NP_499360.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes MNP1(YGL068W)4
    MNP11
    Protein associated with the mitochondrial nucleoid; more4
    MNP11
    52.97(n)1
    49.61(a)1
      7(375087-375671)4
    8528111, 4  NP_011447.11, 4 


    ENSEMBL Gene Tree for MRPL12 (if available)
    TreeFam Gene Tree for MRPL12 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for MRPL12 gene
    2 SIMAP similar genes for MRPL12 using alignment to 1 protein entry:     RM12_HUMAN:
    MRPL7/L12    SLC25A10

    Find genes that share paralogs with MRPL12           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for MRPL12 (see all 182)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs99116601,2
    C,F--79669696(+) GAACGG/ATGGGA 1 -- us2k14Minor allele frequency- A:0.09NA WA 124
    rs1120257391,2
    C,F--79669733(+) GGGCCA/CGCGGG 1 -- us2k12Minor allele frequency- C:0.06NA 122
    rs80776351,2
    C,F--79669885(+) GACAGA/GGAAAG 1 -- us2k15Minor allele frequency- G:0.38NA WA CSA 8
    rs800173371,2
    C--79669885(+) GACAG-/GGAA  
            
    AGAAG
    1 -- us2k10--------
    rs579854381,2
    C--79669888(+) AGAAG-/AAGTGTGG 1 -- us2k10--------
    rs1419558911,2
    --79669899(+) AAGTGA/TGGAGA 1 -- us2k10--------
    rs1894893051,2
    --79670018(+) TTTGGG/TGCTTT 1 -- us2k10--------
    rs80779591,2
    C,F,A--79670122(+) GGGCGG/AGAGAC 1 -- us2k17Minor allele frequency- A:0.16MN NA CSA WA 429
    rs11328021,2
    C,F,A,H--79670273(+) AAACCT/CGGCGG 1 -- us2k116Minor allele frequency- C:0.45MN NS EA NA WA CSA 977
    rs11328031,2
    C,F,A,H--79670386(+) GAGGTA/GCGGCT 1 -- us2k127Minor allele frequency- G:0.30MN NS EA NA WA CSA 2892

    HapMap Linkage Disequilibrium report for MRPL12 (79670387 - 79674556 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for MRPL12 (see all 14):    About this table    
    Variant IDTypeSubtypePubMed ID
    dgv3335n71CNV Loss21882294
    nsv909116CNV Loss21882294
    nsv909126CNV Loss21882294
    dgv3330n71CNV Loss21882294
    dgv3333n71CNV Loss21882294
    nsv828128CNV Loss20364138
    nsv909109CNV Loss21882294
    nsv909052CNV Loss21882294
    dgv3334n71CNV Loss21882294
    dgv3332n71CNV Loss21882294

    Human Gene Mutation Database (HGMD): MRPL12
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing MRPL12
    DNA2.0 Custom Variant and Variant Library Synthesis for MRPL12

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 602375    OMIM disorders: --


    Find genes that share disorders with MRPL12           About GenesLikeMe

    Genetic Association Database (GAD): MRPL12
    Human Genome Epidemiology (HuGE) Navigator: MRPL12 (1 document)

    Export disorders for MRPL12 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for MRPL12 gene, integrated from 10 sources (see all 33):
    (articles sorted by number of sources associating them with MRPL12)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A delayed-early response nuclear gene encoding MRPL12, the mitochondrial homologue to the bacterial translational regulator L7/L12 protein. (PubMed id 8626705)1, 2, 3, 9 Marty L. and Fort P. (J. Biol. Chem. 1996)
    2. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (PLoS ONE 2010)
    3. hNOA1 interacts with complex I and DAP3 and regulates mitochondrial respiration and apoptosis. (PubMed id 19103604)1, 2 Tang T....Farquhar M.G. (J. Biol. Chem. 2009)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. Expression and human chromosomal localization to 17q25 of the growth-regulated gene encoding the mitochondrial ribosomal protein MRPL12. (PubMed id 9169145)1, 3 Marty L....Fort P. (Genomics 1997)
    6. Human mitochondrial ribosomal protein MRPL12 interacts directly with mitochondrial RNA polymerase to modulate mitochondrial gene expression. (PubMed id 17337445)1, 9 Wang Z....Shadel G.S. (J. Biol. Chem. 2007)
    7. Quantitative study of the interactome of PKCIP involved in the EGF-induced tumor cell chemotaxis. (PubMed id 23402259)1 Chen R....Zhang N. (J. Proteome Res. 2013)
    8. The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells. (PubMed id 23667531)1 Cox J.L....Rizzino A. (PLoS ONE 2013)
    9. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    10. Interactions between peptidyl tRNA hydrolase homologs and the ribosomal release factor Mrf1 in S. pombe mitochondria. (PubMed id 23892058)1 Dujeancourt L....Herbert C.J. (Mitochondrion 2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
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      Query String
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    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 6182 HGNC: 10378 AceView: MRPL12andHGS Ensembl:ENSG00000262814 euGenes: HUgn6182
    ECgene: MRPL12 Kegg: 6182 H-InvDB: MRPL12

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for MRPL12 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for MRPL12 gene:
    Search GeneIP for patents involving MRPL12

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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