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MRPL10 Gene

protein-coding   GIFtS: 53
GCID: GC17M045900

Mitochondrial Ribosomal Protein L10

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Mitochondrial Ribosomal Protein L101 2     RPML82 3
MRPL82 3 5     39S Ribosomal Protein L101
39S Ribosomal Protein L8, Mitochondrial2 3     mitochondrial1
L8mt2 3     39S Ribosomal Protein L10, Mitochondrial2
MRP-L102 3     L10MT2
MRP-L82 3     L10mt3

External Ids:    HGNC: 140551   Entrez Gene: 1249952   Ensembl: ENSG000001591117   OMIM: 6118255   UniProtKB: Q7Z7H83   

Export aliases for MRPL10 gene to outside databases

Previous GC identifers: GC17M045606 GC17M048381 GC17M046242 GC17M046375 GC17M043255 GC17M041269


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for MRPL10 Gene:
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the
mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit.
They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is
reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain
a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and
sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a
39S subunit protein. Sequence analysis identified three transcript variants that encode two different isoforms. A
pseudogene corresponding to this gene is found on chromosome 5q. (provided by RefSeq, Nov 2010)

GeneCards Summary for MRPL10 Gene:
MRPL10 (mitochondrial ribosomal protein L10) is a protein-coding gene. Diseases associated with MRPL10 include atherosclerosis, and malaria. GO annotations related to this gene include structural constituent of ribosome.

Gene Wiki entry for MRPL10 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000017.11  NC_018928.2  NT_010783.16  
Regulatory elements:
   Regulatory transcription factor binding sites in the MRPL10 gene promoter:
         Oct-B1   Pax-5   oct-B2   oct-B3   NF-kappaB   NF-AT4   POU2F1   POU2F1a   HOXA5   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMRPL10 promoter sequence
   Search Chromatin IP Primers for MRPL10

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MRPL10


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q21.32   Ensembl cytogenetic band:  17q21.32   HGNC cytogenetic band: 17q21.3

MRPL10 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MRPL10 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17M045900:  view genomic region     (about GC identifiers)

Start:
45,900,638 bp from pter      End:
45,908,907 bp from pter
Size:
8,270 bases      Orientation:
minus strand
ORGUL member locations:
Legend (see complete legend)

ORGUL Member Locations for MRPL10

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: RM10_HUMAN, Q7Z7H8 (See protein sequence)
Recommended Name: 39S ribosomal protein L10, mitochondrial precursor  
Size: 261 amino acids; 29283 Da
Subunit: Component of the mitochondrial ribosome large subunit (39S) which comprises a 16S rRNA and about 50
distinct proteins (By similarity)
Secondary accessions: A6NGJ4 Q96B80 Q96Q55
Alternative splicing: 2 isoforms:  Q7Z7H8-1   Q7Z7H8-2   

Explore the universe of human proteins at neXtProt for MRPL10: NX_Q7Z7H8

Explore proteomics data for MRPL10 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See MRPL10 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_660298.2  NP_683685.1  

    ENSEMBL proteins: 
     ENSP00000324100   ENSP00000290208   ENSP00000395870   ENSP00000404039   ENSP00000390624  

    MRPL10 Human Recombinant Protein Products:

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    Cloud-Clone Corp. CLIAs for MRPL10


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    MRPL: Mitochondrial ribosomal proteins / large subunits

    1 InterPro protein domain:
     IPR001790 Ribosomal_L10/acidic_P0

    Graphical View of Domain Structure for InterPro Entry Q7Z7H8

    ProtoNet protein and cluster: Q7Z7H8

    UniProtKB/Swiss-Prot: RM10_HUMAN, Q7Z7H8
    Similarity: Belongs to the ribosomal protein L10P family


    MRPL10 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003735structural constituent of ribosome ISS--
    GO:0044822poly(A) RNA binding IDA--
         
    MRPL10 for ontologies           About GeneDecksing


    Phenotypes:
         2 MGI mutant phenotypes (inferred from 1 allele(MGI details for Mrpl10):
     pigmentation  vision/eye 

    MRPL10 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for MRPL10
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       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for MRPL10

    miRNA
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    miRTarBase miRNAs that target MRPL10:
    hsa-mir-1301-3p (MIRT035957), hsa-mir-7-5p (MIRT025750), hsa-mir-503-5p (MIRT041125), hsa-mir-16-5p (MIRT031632)

    Block miRNA regulation of human, mouse, rat MRPL10 using miScript Target Protectors
    1 qRT-PCR Assays for microRNA that regulate MRPL10:
    hsa-miR-492
    SwitchGear 3'UTR luciferase reporter plasmidMRPL10 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat MRPL10

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    GenScript: all cDNA clones in your preferred vector (see all 2): MRPL10 (NM_148887)
    Browse Sino Biological Human cDNA Clones
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MRPL10

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MRPL10


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    RM10_HUMAN, Q7Z7H8: Mitochondrion (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    mitochondrion4
    peroxisome2

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005739mitochondrion IDA--
    GO:0005762mitochondrial large ribosomal subunit ISS--
    GO:0030529ribonucleoprotein complex ISS--

    MRPL10 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for MRPL10 About    
    See pathways by source

    SuperPathContained pathways About
    1CFTR translational fidelity class I mutations
    Ribosome0.54

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    1 Kegg Pathway  (Kegg details for MRPL10):
        Ribosome


    MRPL10 for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for MRPL10
    Interactions:

        Search GeneGlobe Interaction Network for MRPL10

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    Selected Interacting proteins for MRPL10 (Q7Z7H82, 3 ENSP000003241004) via UniProtKB, MINT, STRING, and/or I2D (see all 247)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    USP22Q9UPT92, 3, ENSP000002614974MINT-65789 I2D: score=4 STRING: ENSP00000261497
    ICT1Q141972, 3, ENSP000003015854MINT-8079030 I2D: score=1 STRING: ENSP00000301585
    CAMKK2Q96RR43I2D: score=1 
    AARS2Q5JTZ92MINT-8079030
    AASSQ9UDR52MINT-8079030
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006412translation ISS--
    GO:0042254ribosome biogenesis IEA--

    MRPL10 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for MRPL10 (RM10)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for MRPL10 gene (2 alternative transcripts): 
    NM_145255.3  NM_148887.2  

    Unigene Cluster for MRPL10:

    Mitochondrial ribosomal protein L10
    Hs.347535  [show with all ESTs]
    Unigene Representative Sequence: NR_037575
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000351111(uc002ily.3 uc002ilz.3 uc010wky.2) ENST00000290208
    ENST00000414011 ENST00000421763 ENST00000466016 ENST00000423147 ENST00000480901

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat MRPL10 using miScript Target Protectors
    1 qRT-PCR Assays for microRNA that regulate MRPL10:
    hsa-miR-492
    SwitchGear 3'UTR luciferase reporter plasmidMRPL10 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for MRPL10
    Predesigned siRNA for gene silencing in human, mouse, rat MRPL10
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    GenScript: all cDNA clones in your preferred vector (see all 2): MRPL10 (NM_148887)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MRPL10
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MRPL10
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for MRPL10
    OriGene qSTAR qPCR primer pairs in human, mouse for MRPL10
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat MRPL10
      QuantiTect SYBR Green Assays in human, mouse, rat MRPL10
      QuantiFast Probe-based Assays in human, mouse, rat MRPL10

    Additional mRNA sequence: 

    AK293624.1 BC015904.1 BC039852.1 BC052601.1 NR_037575.1 

    10 DOTS entries:

    DT.100060183  DT.95169840  DT.91764845  DT.100798618  DT.95194364  DT.100798603  DT.40194590  DT.100798604 
    DT.100798611  DT.95169784 

    Selected AceView cDNA sequences (see all 404):

    CF128392 BM830221 BQ225382 BQ685868 BQ270443 NM_145255 BM904371 AW328604 
    AI183317 CR619625 BI829153 CR621367 AA303866 BM045348 AA279823 AI336123 
    BU956128 BI911597 BQ420635 BU688356 AL552088 AI033743 AL522686 AA743072 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for MRPL10 (see all 6)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b ^ 4a · 4b ^ 5a · 5b ^ 6 ^ 7a · 7b · 7c
    SP1:                    -     -     -                 -           -                           
    SP2:                    -     -     -     -           -           -                           
    SP3:                                                  -           -                           
    SP4:                    -     -     -     -           -                                       
    SP5:                    -                                                                     


    ECgene alternative splicing isoforms for MRPL10

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    MRPL10 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CAGTTAGTAA
    MRPL10 Expression
    About this image

    MRPL10 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    MRPL10 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.347535
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MRPL10

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for MRPL10 gene from Selected species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Mrpl101 , 5 mitochondrial ribosomal protein L101, 5 81.99(n)1
    78.16(a)1
      11 (60.69 cM)5
    1077321  NM_026154.11  NP_080430.11 
     970415605 
    chicken
    (Gallus gallus)
    Aves MRPL101 mitochondrial ribosomal protein L10 60.51(n)
    54.95(a)
      426521  XM_424160.3  XP_424160.1 
    lizard
    (Anolis carolinensis)
    Reptilia MRPL106
    mitochondrial ribosomal protein L10
    52(a)
    1 ↔ 1
    6(74534231-74545834)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.18902 Transcribed sequence with weak similarity to protein more 74(n)    CF781030.1 
    zebrafish
    (Danio rerio)
    Actinopterygii mrpl101 mitochondrial ribosomal protein L10 55.19(n)
    49.79(a)
      541330  NM_001013458.2  NP_001013476.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta mRpL101 mitochondrial ribosomal protein L10 45.09(n)
    24.9(a)
      33182  NM_078716.3  NP_523440.1 


    ENSEMBL Gene Tree for MRPL10 (if available)
    TreeFam Gene Tree for MRPL10 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for MRPL10 gene

    MRPL10 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for MRPL10
    PGOHUM00000251391


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for MRPL10 (see all 158)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1849192431,2
    --45901196(+) CTTGGC/TTGAGC 3 -- ut31 nc-transcript-variant0--------
    rs1477786341,2
    --45901219(+) GCAGG-/GTTTGTG 3 -- ut31 nc-transcript-variant0--------
    rs1889033661,2
    C--45901251(+) AGCCCA/GTGCAG 3 -- ut31 nc-transcript-variant0--------
    rs115388671,2
    C,F--45901378(-) GGCTTC/TGTCCT 3 -- ut31 nc-transcript-variantese35Minor allele frequency- T:0.20NA WA 244
    rs1507307741,2
    C--45901447(+) TATCAC/TTACTA 3 -- ut31 nc-transcript-variant0--------
    rs7019841,2
    C,F,A,H--45901480(-) GGTCGG/AGGAGT 3 -- ut31 nc-transcript-variant25Minor allele frequency- A:0.31NA EA MN NS WA 2898
    rs1922313071,2
    C--45901530(+) AATAAC/TGCAGA 3 -- ut31 nc-transcript-variant0--------
    rs2020529961,2
    --45901559(+) CTGGCC/TAAACA 3 -- ut31 nc-transcript-variant0--------
    rs1846432711,2
    C--45901575(+) GCTACA/GAGTCC 5 S L mis10--------
    rs1899694211,2
    C--45901579(+) CGAGTA/CCGGAA 5 D Y mis10--------

    HapMap Linkage Disequilibrium report for MRPL10 (45900638 - 45908907 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for MRPL10:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv908574CNV Loss21882294
    nsv908573CNV Loss21882294
    nsv518892CNV Loss19592680
    nsv517880CNV Loss19592680
    nsv908572CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing MRPL10
    DNA2.0 Custom Variant and Variant Library Synthesis for MRPL10

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 611825    OMIM disorders: --

    4 diseases for MRPL10:    
    About MalaCards
    atherosclerosis    malaria    alzheimer's disease    neuronitis


    MRPL10 for disorders           About GeneDecksing

    Genetic Association Database (GAD): MRPL10
    Human Genome Epidemiology (HuGE) Navigator: MRPL10 (6 documents)

    Export disorders for MRPL10 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for MRPL10 gene, integrated from 10 sources (see all 27):
    (articles sorted by number of sources associating them with MRPL10)
        Utopia: connect your pdf to the dynamic
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    1. The large subunit of the mammalian mitochondrial ribosome. Analysis of the complement of ribosomal proteins present. (PubMed id 11551941)1, 2, 3 Koc E.C.... Spremulli L.L. (J. Biol. Chem. 2001)
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    3. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (PLoS ONE 2010)
    4. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (Diabetes Care 2010)
    5. Integrative predictive model of coronary artery calcification in atherosclerosis. (PubMed id 19948975)1, 4 McGeachie M....Ramoni M.F. (Circulation 2009)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    7. The human mitochondrial ribosomal protein genes: mapping of 54 genes to the chromosomes and implications for human disorders. (PubMed id 11543634)1, 2 Kenmochi N.... Tanaka T. (Genomics 2001)
    8. Genome-wide association study of the rate of cognitive decline in Alzheimer's disease. (PubMed id 23535033)1 Sherva R....Green R.C. (amp 2014)
    9. Quantitative study of the interactome of PKCIP involved in the EGF-induced tumor cell chemotaxis. (PubMed id 23402259)1 Chen R....Zhang N. (J. Proteome Res. 2013)
    10. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)

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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 124995 HGNC: 14055 AceView: MRPL10 Ensembl:ENSG00000159111 euGenes: HUgn124995
    ECgene: MRPL10 Kegg: 124995 H-InvDB: MRPL10

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for MRPL10 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for MRPL10 gene:
    Search GeneIP for patents involving MRPL10

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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