Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

MRP63 Gene

protein-coding   GIFtS: 43
GCID: GC13P021750

Mitochondrial Ribosomal Protein 63

  Search for MRP63
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Mitochondrial Ribosomal Protein 631 2
hMRP632 3
bMRP632
Mitochondrial Ribosomal Protein BMRP632
Ribosomal Protein 63, Mitochondrial2

External Ids:    HGNC: 145141   Entrez Gene: 789882   Ensembl: ENSG000001731417   OMIM: 6119975   UniProtKB: Q9BQC63   

Export aliases for MRP63 gene to outside databases

Previous GC identifers: GC13P019730 GC13P015730 GC13P020680 GC13P019548 GC13P020648 GC13P002551


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for MRP63 Gene:
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the
mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit.
They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is
reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain
a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and
sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a
protein which belongs to an undetermined ribosomal subunit and which seems to be specific to animal
mitoribosomes. Pseudogenes corresponding to this gene are found on chromosomes 1p, 1q, 3p, 5q, 8q, 14q, and Y.
(provided by RefSeq, Jul 2008)

GeneCards Summary for MRP63 Gene: 
MRP63 (mitochondrial ribosomal protein 63) is a protein-coding gene. GO annotations related to this gene include structural constituent of ribosome.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000013.10  NC_018924.2  NT_024524.14  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the MRP63 gene promoter:
         STAT1   Pax-5   NRSF form 1   POU3F1   STAT1beta   NRSF form 2   LCR-F1   STAT1alpha   GATA-1   Sox9   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMRP63 promoter sequence
   Search SABiosciences Chromatin IP Primers for MRP63

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MRP63


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 13q12.11   Ensembl cytogenetic band:  13q12.11   HGNC cytogenetic band: 13q12.11

MRP63 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MRP63 gene location

GeneLoc information about chromosome 13         GeneLoc Exon Structure

GeneLoc location for GC13P021750:  view genomic region     (about GC identifiers)

Start:
21,750,372 bp from pter      End:
21,753,223 bp from pter
Size:
2,852 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: RT63_HUMAN, Q9BQC6 (See protein sequence)
Recommended Name: Ribosomal protein 63, mitochondrial  
Size: 102 amino acids; 12266 Da
Subcellular location: Mitochondrion (By similarity)
Miscellaneous: Identified only in the intact 55S subunit. It is unknown whether it belongs to the 28S or to the
39S subunit. May localize at the subunit interface and dissociate from the 55S mitoribosome during subunit
separation
Secondary accessions: A2A332

Explore the universe of human proteins at neXtProt for MRP63: NX_Q9BQC6

Explore proteomics data for MRP63 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9BQC6

  • MRP63 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    MRP63 Protein Expression
    REFSEQ proteins: NP_076931.1  
    ENSEMBL proteins: 
     ENSP00000310726  

    Human Recombinant Protein Products for MRP63: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    Browse OriGene Protein Over-expression Lysates
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for MRP63
    GenScript Custom Purified and Recombinant Proteins Services for MRP63
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for MRP63 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion ----
    GO:0005761mitochondrial ribosome IEA--

    MRP63 for ontologies           About GeneDecksing



    MRP63 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for MRP63
    GenScript Custom Superior Antibodies Services for MRP63
    Novus Biologicals MRP63 Antibody
    Abcam antibodies for MRP63
    Cloud-Clone Corp. Antibodies for MRP63 
    Search ThermoFisher Antibodies for MRP63
    Search LSBio for Antibodies for MRP63 

    Assay Products for MRP63: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for MRP63
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for MRP63
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for MRP63 
    Cloud-Clone Corp. CLIAs for MRP63


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    MRPO: Mitochondrial ribosomal proteins / "other"

    1 InterPro protein domain:
     IPR016576 Ribosomal_MRP63_mit

    Graphical View of Domain Structure for InterPro Entry Q9BQC6

    ProtoNet protein and cluster: Q9BQC6


    MRP63 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003735structural constituent of ribosome IEA--
         
    MRP63 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for MRP63 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for MRP63

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for MRP63 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for MRP63 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MRP63
    1 QIAGEN miScript miRNA Assays for microRNA that regulate MRP63:
    hsa-miR-141*
    SwitchGear 3'UTR luciferase reporter plasmidMRP63 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for MRP63
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MRP63

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for MRP63
    Sirion Biotech Customized adenovirus for overexpression of MRP63

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for MRP63 (see all 6)
    OriGene ORF clones in mouse, rat for MRP63
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: MRP63 (NM_024026)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MRP63
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MRP63
    Sirion Biotech Customized lentivirus for stable overexpression of MRP63 
                         Customized lentivirus expression plasmids for stable overexpression of MRP63 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for MRP63
    Search LifeMap BioReagents cell lines for MRP63
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MRP63


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MRP63

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for MRP63 (Q9BQC63 ENSP000003107264) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    EPB41P111713, ENSP000002901004I2D: score=1 STRING: ENSP00000290100
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006412translation IEA--

    MRP63 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for MRP63 (RT63)

    Search CenterWatch for drugs/clinical trials and news about MRP63 / RT63

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for MRP63 gene: 
    NM_024026.4  

    Unigene Cluster for MRP63:

    Mitochondrial ribosomal protein 63
    Hs.458367  [show with all ESTs]
    Unigene Representative Sequence: NM_024026
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000309594(uc001unw.3)
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MRP63
    1 QIAGEN miScript miRNA Assays for microRNA that regulate MRP63:
    hsa-miR-141*
    SwitchGear 3'UTR luciferase reporter plasmidMRP63 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for MRP63
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MRP63
    Clone
    Products:
         
    OriGene clones in human, mouse for MRP63 (see all 6)
    OriGene ORF clones in mouse, rat for MRP63
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: MRP63 (NM_024026)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MRP63
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MRP63
    Sirion Biotech Customized lentivirus for stable overexpression of MRP63 
                         Customized lentivirus expression plasmids for stable overexpression of MRP63 
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for MRP63
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat MRP63
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MRP63
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MRP63

    Additional mRNA sequence: 

    AB049957.1 BC023616.2 BC068492.1 

    7 DOTS entries:

    DT.435699  DT.92427399  DT.116749  DT.455709  DT.99943061  DT.441004  DT.95163667 

    24/87 AceView cDNA sequences (see all 87):

    AW592151 AB049957 F25277 AW445203 NM_024026 CF890784 BC023616 BI761165 
    BQ082763 AA316019 CF887066 C02370 BM984235 AW082297 BX473801 BE299970 
    BF792501 F12316 BQ876511 BU679712 BE278918 BF973934 BI550854 BE407715 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    MRP63 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CCGCTGCACT
    MRP63 Expression
    About this image


    See MRP63 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for MRP63

    SOURCE GeneReport for Unigene cluster: Hs.458367
        SABiosciences Custom PCR Arrays for MRP63
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for MRP63
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat MRP63
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MRP63
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MRP63
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MRP63

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for MRP63 gene from 4/11 species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Mrp631 , 5 mitochondrial ribosomal protein 631, 5 82.35(n)1
    83.33(a)1
      14 (30.51 cM)5
    678401  NM_026401.21  NP_080677.11 
     578262395 
    chicken
    (Gallus gallus)
    Aves MRP631 mitochondrial ribosomal protein 63 60.78(n)
    61.76(a)
      771615  XM_003640581.1  XP_003640629.1 
    lizard
    (Anolis carolinensis)
    Reptilia MRP636
    Uncharacterized protein
    66(a)
    1 ↔ 1
    3(187794947-187795252)
    zebrafish
    (Danio rerio)
    Actinopterygii mrp631 mitochondrial ribosomal protein 63 61.06(n)
    62.38(a)
      393748  NM_200775.1  NP_957069.1 


    ENSEMBL Gene Tree for MRP63 (if available)
    TreeFam Gene Tree for MRP63 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for MRP63 gene

    MRP63 for paralogs           About GeneDecksing


    4 Pseudogenes.org Pseudogenes for MRP63
    PGOHUM00000244152 PGOHUM00000238021 PGOHUM00000235826 PGOHUM00000249448


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/35 SNPs in MRP63 are shown (see all 35)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 13 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs357975961,2
    C,F--21752870(+) TGGGCG/AGATCA 1 -- ut313Minor allele frequency- A:0.33NA 6
    rs1914752171,2
    --21752903(+) GCCTGA/GCCAAT 1 -- ut310--------
    rs1497243701,2
    C--21752914(+) ATGGTA/GAAACC 1 -- ut310--------
    rs11370351,2
    C,F,H--21752982(-) ttacaG/Agcatg 1 -- ut314Minor allele frequency- A:0.01NS NA 410
    rs1467342191,2
    --21753113(+) AAAAAA/CTACAT 1 -- ut310--------
    rs1402792711,2
    --21753162(+) TTAATA/GTACCA 1 -- ut310--------
    rs777765061,2
    F--21753164(+) AATATG/ACCATG 1 -- ut311Minor allele frequency- A:0.50CSA 2
    rs73352371,2
    C,A--21753255(+) TATAGC/TAGTGT 1 -- ds500112Minor allele frequency- T:0.09NA WA CSA EA 374
    rs571507551,2
    C,F--21753279(+) ATACAA/GTATGC 1 -- ds50011Minor allele frequency- G:0.03WA 118
    rs1464218321,2
    --21753290(+) ATTTGA/GTGACA 1 -- ds50010--------

    HapMap Linkage Disequilibrium report for MRP63 (21750372 - 21753223 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for MRP63:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2747099CNV Deletion23290073
    nsv899878CNV Gain21882294

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing MRP63
    DNA2.0 Custom Variant and Variant Library Synthesis for MRP63

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    MRP63 for disorders           About MalaCards
    OMIM gene information: 611997    OMIM disorders: --


    MRP63 for disorders           About GeneDecksing

    Genetic Association Database (GAD): MRP63
    Human Genome Epidemiology (HuGE) Navigator: MRP63 (1 document)

    Export disorders for MRP63 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for MRP63 gene, integrated from 9 sources (see all 12):
    (articles sorted by number of sources associating them with MRP63)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Genetic variants in nuclear-encoded mitochondrial gen es influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (2010)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Proteomic analysis of the mammalian mitochondrial ribosome. Identification of protein components in the 28S small subunit. (PubMed id 11402041)1, 2 Suzuki T....Watanabe K. (2001)
    4. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    5. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    6. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    7. The DNA sequence and analysis of human chromosome 13. (PubMed id 15057823)2 Dunham A.... Ross M.T. (2004)
    8. A common set of gene regulatory networks links metabolism and growth inhibition. (PubMed id 15525513)1 Cam H....Dynlacht B.D. (2004)
    9. Identification and characterization of over 100 mitochondrial ribosomal protein pseudogenes in the human genome. (PubMed id 12706105)1 Zhang Z. and Gerstein M. (2003)
    10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 78988 HGNC: 14514 AceView: MRP63 Ensembl:ENSG00000173141 euGenes: HUgn78988
    ECgene: MRP63 H-InvDB: MRP63

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for MRP63 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for MRP63 gene:
    Search GeneIP for patents involving MRP63

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for MRP63  
     Browse OriGene qPCR primer pairs and template standards   Browse OriGene Protein Over-expression Lysates  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for MRP63  
     OriGene qSTAR qPCR primer pairs in human, mouse for MRP63   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for MRP63   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for MRP63   OriGene Custom Protein Services for MRP63  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat MRP63
     QIAGEN SeqTarget long-range PCR primers for resequencing MRP63
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MRP63
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MRP63
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MRP63
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MRP63
     GenScript Custom Purified and Recombinant Proteins Services for MRP63 GenScript cDNA clones with any tag delivered in your preferred vector for MRP63
     GenScript Custom Assay Services for MRP63 GenScript Custom Superior Antibodies Services for MRP63
     GenScript Custom overexpressing Cell Line Services for MRP63 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in MRP63 promoter
     Search Chromatin IP Primers for MRP63
     RT2 qPCR Primer Assay in human, mouse, rat MRP63
     Search GNC Networks for MRP63
     SABiosciences Custom PCR Arrays for MRP63
     Search Tocris compounds for MRP63 (RT63)
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     MRP63 antibodies
     Antibodies for MRP63
     See all of Abcam's Antibodies, Kits and Proteins for MRP63
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Proteins for MRP63
     Antibodies for MRP63
     ELISAs for MRP63
     CLIAs for MRP63
     Search LifeMap BioReagents cell lines for MRP63
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MRP63
     SwitchGear 3'UTR luciferase reporter plasmids for MRP63
     SwitchGear Promoter luciferase reporter plasmids for MRP63
     Search ThermoFisher Antibodies for MRP63
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MRP63
     inGenious Targeting Laboratory - Custom generated mouse model solutions for MRP63
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for MRP63
    Customized:
     lentivirus for stable overexpression of MRP63
     lentivirus expression plasmids for stable overexpression of MRP63
     adenovirus for overexpression of MRP63
     Search LSBio for Antibodies for MRP63
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      MRP63 gene at Home site.
    hostname: 356977-web1.xennexinc.com index build: 106 solr: 1.4