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Aliases for MROH9 Gene

Aliases for MROH9 Gene

  • Maestro Heat Like Repeat Family Member 9 2 3 5
  • C1orf129 3 4
  • Maestro Heat-Like Repeat-Containing Protein Family Member 9 3
  • Maestro Heat-Like Repeat Family Member 9 2
  • Chromosome 1 Open Reading Frame 129 2
  • Armadillo Repeat Containing 11 3
  • ARMC11 3

External Ids for MROH9 Gene

Previous HGNC Symbols for MROH9 Gene

  • C1orf129

Summaries for MROH9 Gene

GeneCards Summary for MROH9 Gene

MROH9 (Maestro Heat Like Repeat Family Member 9) is a Protein Coding gene. GO annotations related to this gene include binding. An important paralog of this gene is MROH8.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MROH9 Gene

Genomics for MROH9 Gene

Regulatory Elements for MROH9 Gene

Enhancers for MROH9 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01G171217 1.3 FANTOM5 Ensembl ENCODE 1.3 +285.1 285087 5.3 CTCF TEAD4 RBBP5 CHD7 RAD21 POLR2A SMC3 MAFK MIXL1 ZNF654 FMO2 ENSG00000231424 FMO3 MROH9 ENSG00000225243
GH01G171201 0.5 FANTOM5 2 +266.5 266463 0.2 ZSCAN5C NR2F1 FMO2 FMO3 MROH9 ENSG00000225243
GH01G170929 0.9 Ensembl ENCODE 0.4 -5.6 -5557 1.4 CTCF ZNF654 PKNOX1 TRIM22 REST RAD21 SMC3 ZNF652 MROH9 GC01M170893
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MROH9 on UCSC Golden Path with GeneCards custom track

Genomic Location for MROH9 Gene

170,935,471 bp from pter
171,065,985 bp from pter
130,515 bases
Plus strand

Genomic View for MROH9 Gene

Genes around MROH9 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MROH9 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MROH9 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MROH9 Gene

Proteins for MROH9 Gene

  • Protein details for MROH9 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Maestro heat-like repeat-containing protein family member 9
    Protein Accession:
    Secondary Accessions:
    • A0PJM0
    • A0PJM2
    • F5GWX6
    • Q9H5D7

    Protein attributes for MROH9 Gene

    573 amino acids
    Molecular mass:
    65050 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAB15690.1; Type=Frameshift; Positions=507; Evidence={ECO:0000305};

    Alternative splice isoforms for MROH9 Gene


neXtProt entry for MROH9 Gene

Post-translational modifications for MROH9 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for MROH9 Gene

No data available for DME Specific Peptides for MROH9 Gene

Domains & Families for MROH9 Gene

Gene Families for MROH9 Gene

Protein Domains for MROH9 Gene


Suggested Antigen Peptide Sequences for MROH9 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MROH9: view

No data available for UniProtKB/Swiss-Prot for MROH9 Gene

Function for MROH9 Gene

Phenotypes for MROH9 Gene

GenomeRNAi human phenotypes for MROH9:
genes like me logo Genes that share phenotypes with MROH9: view

Animal Model Products

CRISPR Products

miRNA for MROH9 Gene

miRTarBase miRNAs that target MROH9

Inhibitory RNA Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for MROH9 Gene

Localization for MROH9 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MROH9 gene
Compartment Confidence
cytosol 2
plasma membrane 1
mitochondrion 1
peroxisome 1
nucleus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for MROH9 Gene

Pathways & Interactions for MROH9 Gene

SuperPathways for MROH9 Gene

No Data Available

Interacting Proteins for MROH9 Gene

Gene Ontology (GO) - Biological Process for MROH9 Gene


No data available for Pathways by source and SIGNOR curated interactions for MROH9 Gene

Drugs & Compounds for MROH9 Gene

No Compound Related Data Available

Transcripts for MROH9 Gene

mRNA/cDNA for MROH9 Gene

(5) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(5) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for MROH9 Gene

Maestro heat-like repeat family member 9:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for MROH9 Gene

No ASD Table

Relevant External Links for MROH9 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MROH9 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MROH9 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for MROH9 Gene

This gene is overexpressed in Testis (x31.1), Cervix - Endocervix (x6.7), and Lung (x6.6).

Protein differential expression in normal tissues from HIPED for MROH9 Gene

This gene is overexpressed in Urine (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for MROH9 Gene

Protein tissue co-expression partners for MROH9 Gene

NURSA nuclear receptor signaling pathways regulating expression of MROH9 Gene:


SOURCE GeneReport for Unigene cluster for MROH9 Gene:

genes like me logo Genes that share expression patterns with MROH9: view

Primer Products

No data available for mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MROH9 Gene

Orthologs for MROH9 Gene

This gene was present in the common ancestor of mammals.

Orthologs for MROH9 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia C1H1orf129 34
  • 98.88 (n)
MROH9 35
  • 92 (a)
(Bos Taurus)
Mammalia C16H1orf129 34
  • 79.39 (n)
MROH9 35
  • 62 (a)
(Canis familiaris)
Mammalia C7H1orf129 34
  • 79.36 (n)
MROH9 35
  • 64 (a)
(Rattus norvegicus)
Mammalia Mroh9 34
  • 73.02 (n)
(Mus musculus)
Mammalia Mroh9 34 16 35
  • 72.26 (n)
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 51 (a)
-- 35
  • 48 (a)
(Monodelphis domestica)
Mammalia MROH9 35
  • 49 (a)
Species where no ortholog for MROH9 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MROH9 Gene

Gene Tree for MROH9 (if available)
Gene Tree for MROH9 (if available)

Paralogs for MROH9 Gene

Paralogs for MROH9 Gene

genes like me logo Genes that share paralogs with MROH9: view

Variants for MROH9 Gene

Sequence variations from dbSNP and Humsavar for MROH9 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1000044245 -- 171,054,289(+) ACACC(C/T)TATTC intron-variant
rs1000053600 -- 171,005,916(+) TATTT(C/T)AATAC intron-variant
rs1000105914 -- 171,017,009(+) CTAAG(G/T)TTTTA intron-variant
rs1000121490 -- 171,002,202(+) CAGTT(C/T)TGTGT intron-variant
rs1000194456 -- 171,063,991(+) AGAGA(G/T)GGAGA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for MROH9 Gene

Variant ID Type Subtype PubMed ID
dgv116e212 CNV loss 25503493
esv28731 CNV gain+loss 19812545
esv3307086 CNV mobile element insertion 20981092
esv3310137 CNV mobile element insertion 20981092
esv3406241 CNV insertion 20981092
esv3578259 CNV loss 25503493
esv3578260 CNV loss 25503493
esv3587909 CNV loss 21293372
esv3587911 CNV loss 21293372
nsv3487 CNV insertion 18451855

Variation tolerance for MROH9 Gene

Residual Variation Intolerance Score: 93.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.21; 69.84% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for MROH9 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MROH9 Gene

Disorders for MROH9 Gene

Relevant External Links for MROH9

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MROH9 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MROH9 Gene

Publications for MROH9 Gene

  1. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3 64
  2. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 4 64
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4 64
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 64
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for MROH9 Gene

Sources for MROH9 Gene

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