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Aliases for MROH5 Gene

Aliases for MROH5 Gene

  • Maestro Heat Like Repeat Family Member 5 2 3
  • Maestro Heat-Like Repeat Family Member 5 2 5

External Ids for MROH5 Gene

Previous GeneCards Identifiers for MROH5 Gene

  • GC08M142444
  • GC08M142445

Summaries for MROH5 Gene

GeneCards Summary for MROH5 Gene

MROH5 (Maestro Heat Like Repeat Family Member 5) is a Protein Coding gene. GO annotations related to this gene include binding. An important paralog of this gene is MROH7-TTC4.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MROH5 Gene

Genomics for MROH5 Gene

Genomic Location for MROH5 Gene

Chromosome:
8
Start:
141,433,829 bp from pter
End:
141,507,230 bp from pter
Size:
73,402 bases
Orientation:
Minus strand

Genomic View for MROH5 Gene

Genes around MROH5 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MROH5 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MROH5 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MROH5 Gene

No data available for Regulatory Elements for MROH5 Gene

Proteins for MROH5 Gene

  • Protein details for MROH5 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6ZUA9-MROH5_HUMAN
    Recommended name:
    Maestro heat-like repeat family member 5
    Protein Accession:
    Q6ZUA9

    Protein attributes for MROH5 Gene

    Size:
    1318 amino acids
    Molecular mass:
    149091 Da
    Quaternary structure:
    No Data Available

neXtProt entry for MROH5 Gene

Proteomics data for MROH5 Gene at MOPED

Post-translational modifications for MROH5 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for MROH5 Gene

No data available for DME Specific Peptides for MROH5 Gene

Domains & Families for MROH5 Gene

Gene Families for MROH5 Gene

Protein Domains for MROH5 Gene

InterPro:
Blocks:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

Q6ZUA9

UniProtKB/Swiss-Prot:

MROH5_HUMAN :
  • Contains 9 HEAT repeats.
Similarity:
  • Contains 9 HEAT repeats.
genes like me logo Genes that share domains with MROH5: view

No data available for Suggested Antigen Peptide Sequences for MROH5 Gene

Function for MROH5 Gene

genes like me logo Genes that share phenotypes with MROH5: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MROH5 Gene

Localization for MROH5 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MROH5 Gene

Pathways & Interactions for MROH5 Gene

SuperPathways for MROH5 Gene

No Data Available

Interacting Proteins for MROH5 Gene

Gene Ontology (GO) - Biological Process for MROH5 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MROH5 Gene

Drugs & Compounds for MROH5 Gene

No Compound Related Data Available

Transcripts for MROH5 Gene

mRNA/cDNA for MROH5 Gene

(1) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(3) Selected AceView cDNA sequences:
(5) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for MROH5 Gene

Maestro heat-like repeat family member 5:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for MROH5 Gene

No ASD Table

Relevant External Links for MROH5 Gene

GeneLoc Exon Structure for
MROH5
ECgene alternative splicing isoforms for
MROH5

Expression for MROH5 Gene

mRNA expression in normal human tissues for MROH5 Gene

mRNA differential expression in normal tissues according to GTEx for MROH5 Gene

This gene is overexpressed in Testis (x38.6).

SOURCE GeneReport for Unigene cluster for MROH5 Gene Hs.689547

genes like me logo Genes that share expression patterns with MROH5: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MROH5 Gene

Orthologs for MROH5 Gene

This gene was present in the common ancestor of mammals.

Orthologs for MROH5 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia LOC100298420 35
  • 81.96 (n)
  • 72.02 (a)
dog
(Canis familiaris)
Mammalia MROH5 35
  • 81.77 (n)
  • 73.82 (a)
platypus
(Ornithorhynchus anatinus)
Mammalia MROH5 36
  • 20 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Mroh5 35
  • 75.27 (n)
  • 67.23 (a)
Species with no ortholog for MROH5:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MROH5 Gene

ENSEMBL:
Gene Tree for MROH5 (if available)
TreeFam:
Gene Tree for MROH5 (if available)

Paralogs for MROH5 Gene

Paralogs for MROH5 Gene

Pseudogenes.org Pseudogenes for MROH5 Gene

genes like me logo Genes that share paralogs with MROH5: view

Variants for MROH5 Gene

Sequence variations from dbSNP and Humsavar for MROH5 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type
rs1884312 -- 141,497,181(-) cagag(A/G)ccagc intron-variant
rs1993714 -- 141,473,927(-) TGGTA(A/G)AAAGA intron-variant
rs1993715 -- 141,473,883(-) gtaat(C/T)tcaac intron-variant
rs2126099 -- 141,474,044(-) AGACA(A/G)GGCGG intron-variant, nc-transcript-variant
rs2613639 -- 141,490,371(-) TCCTG(C/G)CCCTC intron-variant

Relevant External Links for MROH5 Gene

HapMap Linkage Disequilibrium report
MROH5

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MROH5 Gene

Disorders for MROH5 Gene

Relevant External Links for MROH5

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MROH5

No disorders were found for MROH5 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MROH5 Gene

Publications for MROH5 Gene

  1. Genetics of coronary artery calcification among African Americans, a meta-analysis. (PMID: 23870195) Wojczynski M.K. … Reilly M.P. (BMC Med. Genet. 2013) 3 67
  2. Toward an understanding of the protein interaction network of the human liver. (PMID: 21988832) Wang J. … Yang X. (Mol. Syst. Biol. 2011) 3
  3. Genome-scale RNAi screen for host factors required for HIV replication. (PMID: 18976975) Zhou H. … Espeseth A.S. (Cell Host Microbe 2008) 3
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for MROH5 Gene

Sources for MROH5 Gene

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