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Aliases for MROH5 Gene

Aliases for MROH5 Gene

  • Maestro Heat Like Repeat Family Member 5 2 3 5
  • Maestro Heat-Like Repeat Family Member 5 2

External Ids for MROH5 Gene

Previous GeneCards Identifiers for MROH5 Gene

  • GC08M142444
  • GC08M142445

Summaries for MROH5 Gene

GeneCards Summary for MROH5 Gene

MROH5 (Maestro Heat Like Repeat Family Member 5) is a Protein Coding gene. GO annotations related to this gene include binding. An important paralog of this gene is MROH1.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MROH5 Gene

Genomics for MROH5 Gene

Regulatory Elements for MROH5 Gene

Enhancers for MROH5 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around MROH5 on UCSC Golden Path with GeneCards custom track

Genomic Location for MROH5 Gene

Chromosome:
8
Start:
141,433,829 bp from pter
End:
141,507,230 bp from pter
Size:
73,402 bases
Orientation:
Minus strand

Genomic View for MROH5 Gene

Genes around MROH5 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MROH5 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MROH5 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MROH5 Gene

Proteins for MROH5 Gene

  • Protein details for MROH5 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6ZUA9-MROH5_HUMAN
    Recommended name:
    Maestro heat-like repeat family member 5
    Protein Accession:
    Q6ZUA9

    Protein attributes for MROH5 Gene

    Size:
    1318 amino acids
    Molecular mass:
    149091 Da
    Quaternary structure:
    No Data Available

neXtProt entry for MROH5 Gene

Post-translational modifications for MROH5 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for MROH5 Gene

No data available for DME Specific Peptides for MROH5 Gene

Domains & Families for MROH5 Gene

Gene Families for MROH5 Gene

Protein Domains for MROH5 Gene

InterPro:
Blocks:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

Q6ZUA9

UniProtKB/Swiss-Prot:

MROH5_HUMAN :
  • Contains 9 HEAT repeats.
Similarity:
  • Contains 9 HEAT repeats.
genes like me logo Genes that share domains with MROH5: view

No data available for Suggested Antigen Peptide Sequences for MROH5 Gene

Function for MROH5 Gene

genes like me logo Genes that share phenotypes with MROH5: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MROH5 Gene

Localization for MROH5 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MROH5 Gene

Pathways & Interactions for MROH5 Gene

SuperPathways for MROH5 Gene

No Data Available

Interacting Proteins for MROH5 Gene

Selected Interacting proteins: Q6ZUA9-MROH5_HUMAN for MROH5 Gene via IID

Symbol External ID(s) Details
ASGR2

Gene Ontology (GO) - Biological Process for MROH5 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MROH5 Gene

Drugs & Compounds for MROH5 Gene

No Compound Related Data Available

Transcripts for MROH5 Gene

mRNA/cDNA for MROH5 Gene

(1) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(3) Selected AceView cDNA sequences:
(5) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for MROH5 Gene

Maestro heat-like repeat family member 5:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MROH5 Gene

No ASD Table

Relevant External Links for MROH5 Gene

GeneLoc Exon Structure for
MROH5
ECgene alternative splicing isoforms for
MROH5

Expression for MROH5 Gene

mRNA expression in normal human tissues for MROH5 Gene

mRNA differential expression in normal tissues according to GTEx for MROH5 Gene

This gene is overexpressed in Testis (x38.6).

NURSA nuclear receptor signaling pathways regulating expression of MROH5 Gene:

MROH5

SOURCE GeneReport for Unigene cluster for MROH5 Gene:

Hs.689547
genes like me logo Genes that share expression patterns with MROH5: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MROH5 Gene

Orthologs for MROH5 Gene

This gene was present in the common ancestor of mammals.

Orthologs for MROH5 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia LOC100298420 34
  • 81.96 (n)
  • 72.02 (a)
dog
(Canis familiaris)
Mammalia MROH5 34
  • 81.77 (n)
  • 73.82 (a)
rat
(Rattus norvegicus)
Mammalia Mroh5 34
  • 75.27 (n)
  • 67.23 (a)
platypus
(Ornithorhynchus anatinus)
Mammalia MROH5 35
  • 20 (a)
OneToOne
Species where no ortholog for MROH5 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MROH5 Gene

ENSEMBL:
Gene Tree for MROH5 (if available)
TreeFam:
Gene Tree for MROH5 (if available)

Paralogs for MROH5 Gene

Paralogs for MROH5 Gene

Pseudogenes.org Pseudogenes for MROH5 Gene

genes like me logo Genes that share paralogs with MROH5: view

Variants for MROH5 Gene

Sequence variations from dbSNP and Humsavar for MROH5 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type
rs1884312 -- 141,497,181(-) cagag(A/G)ccagc intron-variant
rs1993713 -- 141,474,057(-) GGCAT(C/T)TCAGA intron-variant, nc-transcript-variant
rs1993714 -- 141,473,927(-) TGGTA(A/G)AAAGA intron-variant
rs1993715 -- 141,473,883(-) gtaat(C/T)tcaac intron-variant
rs2126099 -- 141,474,044(-) AGACA(A/G)GGCGG intron-variant, nc-transcript-variant

Structural Variations from Database of Genomic Variants (DGV) for MROH5 Gene

Variant ID Type Subtype PubMed ID
dgv12368n54 CNV loss 21841781
dgv12369n54 CNV loss 21841781
dgv12370n54 CNV loss 21841781
dgv12n35 CNV novel sequence insertion 20440878
dgv4256e59 CNV duplication 20981092
dgv7331n100 CNV gain 25217958
dgv902n27 CNV loss 19166990
esv1007571 CNV deletion 20482838
esv1160693 CNV deletion 17803354
esv1393576 CNV insertion 17803354
esv1434042 CNV insertion 17803354
esv22145 CNV gain+loss 19812545
esv2268193 CNV deletion 18987734
esv2668843 CNV deletion 23128226
esv2675279 CNV deletion 23128226
esv2737756 CNV deletion 23290073
esv2737783 CNV deletion 23290073
esv2737785 CNV deletion 23290073
esv2737786 CNV deletion 23290073
esv2737787 CNV deletion 23290073
esv2737788 CNV deletion 23290073
esv2737789 CNV deletion 23290073
esv2737790 CNV deletion 23290073
esv2737791 CNV deletion 23290073
esv2737792 CNV deletion 23290073
esv2737793 CNV deletion 23290073
esv2737794 CNV deletion 23290073
esv2737796 CNV deletion 23290073
esv3418206 CNV duplication 20981092
esv3429058 CNV duplication 20981092
esv3891495 CNV gain 25118596
esv988730 CNV insertion 20482838
nsv1023036 CNV loss 25217958
nsv1075588 CNV deletion 25765185
nsv1078855 CNV insertion 25765185
nsv1126125 CNV deletion 24896259
nsv1151677 CNV deletion 26484159
nsv397559 CNV deletion 16902084
nsv398406 CNV deletion 16902084
nsv465958 CNV loss 19166990
nsv465964 CNV loss 19166990
nsv465966 CNV loss 19166990
nsv470240 CNV loss 18288195
nsv472865 CNV novel sequence insertion 20440878
nsv476679 CNV novel sequence insertion 20440878
nsv476945 CNV novel sequence insertion 20440878
nsv478138 CNV novel sequence insertion 20440878
nsv509285 CNV insertion 20534489
nsv517560 CNV gain+loss 19592680
nsv521766 CNV gain 19592680
nsv524817 CNV loss 19592680
nsv612577 CNV loss 21841781
nsv612582 CNV loss 21841781
nsv612585 CNV loss 21841781
nsv6433 CNV insertion 18451855
nsv824751 CNV gain 20364138
nsv949996 CNV deletion 24416366
nsv971703 CNV duplication 23825009

Relevant External Links for MROH5 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MROH5

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MROH5 Gene

Disorders for MROH5 Gene

Relevant External Links for MROH5

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MROH5

No disorders were found for MROH5 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MROH5 Gene

Publications for MROH5 Gene

  1. Genetics of coronary artery calcification among African Americans, a meta-analysis. (PMID: 23870195) Wojczynski M.K. … Reilly M.P. (BMC Med. Genet. 2013) 3 65
  2. Toward an understanding of the protein interaction network of the human liver. (PMID: 21988832) Wang J. … Yang X. (Mol. Syst. Biol. 2011) 3 65
  3. Genome-scale RNAi screen for host factors required for HIV replication. (PMID: 18976975) Zhou H. … Espeseth A.S. (Cell Host Microbe 2008) 3 65
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3 65
  5. DNA sequence and analysis of human chromosome 8. (PMID: 16421571) Nusbaum C. … Lander E.S. (Nature 2006) 4 65

Products for MROH5 Gene

Sources for MROH5 Gene

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