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Aliases for MROH2B Gene

Aliases for MROH2B Gene

  • Maestro Heat-Like Repeat Family Member 2B 2 3
  • HEAT Repeat-Containing Protein 7B2 3 4
  • HEAT Repeat Family Member 7B2 2 3
  • HEATR7B2 3 4
  • Maestro Heat-Like Repeat-Containing Protein Family Member 2B 3
  • HEAT Repeat Family Member B2 3

External Ids for MROH2B Gene

Previous HGNC Symbols for MROH2B Gene

  • HEATR7B2

Summaries for MROH2B Gene

GeneCards Summary for MROH2B Gene

MROH2B (Maestro Heat-Like Repeat Family Member 2B) is a Protein Coding gene. An important paralog of this gene is MROH7-TTC4.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MROH2B Gene

Genomics for MROH2B Gene

Genomic Location for MROH2B Gene

40,998,017 bp from pter
41,071,342 bp from pter
73,326 bases
Minus strand

Genomic View for MROH2B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MROH2B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MROH2B Gene

No data available for Regulatory Elements for MROH2B Gene

Proteins for MROH2B Gene

  • Protein details for MROH2B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Maestro heat-like repeat-containing protein family member 2B
    Protein Accession:
    Secondary Accessions:
    • Q68DM1
    • Q7Z4U4
    • Q8N7X3

    Protein attributes for MROH2B Gene

    1585 amino acids
    Molecular mass:
    180781 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAP97306.1; Type=Frameshift; Positions=1063, 1080; Evidence={ECO:0000305}; Sequence=BAC05103.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

    Alternative splice isoforms for MROH2B Gene


neXtProt entry for MROH2B Gene

Proteomics data for MROH2B Gene at MOPED

Post-translational modifications for MROH2B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for MROH2B Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for MROH2B Gene

Domains for MROH2B Gene

Gene Families for MROH2B Gene

  • MROH :maestro heat-like repeat containing

Protein Domains for MROH2B Gene


Graphical View of Domain Structure for InterPro Entry



  • Q7Z745
  • Contains 15 HEAT repeats.
genes like me logo Genes that share domains with MROH2B: view

No data available for Suggested Antigen Peptide Sequences for MROH2B Gene

Function for MROH2B Gene

Gene Ontology (GO) - Molecular Function for MROH2B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005488 binding --
genes like me logo Genes that share ontologies with MROH2B: view

Animal Model Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for MROH2B

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MROH2B Gene

Localization for MROH2B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MROH2B Gene

Pathways for MROH2B Gene

SuperPathways for MROH2B Gene

No Data Available

Interacting Proteins for MROH2B Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
Selected Interacting proteins: ENSP00000382476 for MROH2B Gene via STRING

Gene Ontology (GO) - Biological Process for MROH2B Gene


No data available for Pathways by source for MROH2B Gene

Transcripts for MROH2B Gene

Unigene Clusters for MROH2B Gene

Maestro heat-like repeat family member 2B:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for MROH2B

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MROH2B Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^ 21 ^ 22 ^ 23 ^ 24 ^ 25 ^
SP1: - -

ExUns: 26 ^ 27 ^ 28 ^ 29 ^ 30 ^ 31 ^ 32 ^ 33 ^ 34 ^ 35 ^ 36 ^ 37 ^ 38 ^ 39 ^ 40 ^ 41a · 41b ^ 42 ^ 43
SP1: - -
SP2: -

Relevant External Links for MROH2B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MROH2B Gene

mRNA expression in normal human tissues for MROH2B Gene

mRNA differential expression in normal tissues according to GTEx for MROH2B Gene

This gene is overexpressed in Testis (50.0).

Protein differential expression in normal tissues for MROH2B Gene

This gene is overexpressed in Nasopharynx (25.1) and Bone marrow stromal cell (17.9).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for MROH2B Gene

SOURCE GeneReport for Unigene cluster for MROH2B Gene Hs.97714

genes like me logo Genes that share expressions with MROH2B: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt and Expression partners for MROH2B Gene

Orthologs for MROH2B Gene

This gene was present in the common ancestor of animals.

Orthologs for MROH2B Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia MROH2B 35
  • 86.52 (n)
  • 85.3 (a)
  • 85 (a)
(Canis familiaris)
Mammalia MROH2B 35
  • 88.39 (n)
  • 87.13 (a)
  • 87 (a)
(Mus musculus)
Mammalia Mroh2b 35
  • 82.57 (n)
  • 81.65 (a)
Mroh2b 16
Mroh2b 36
  • 82 (a)
(Pan troglodytes)
Mammalia HEATR7B2 35
  • 99.24 (n)
  • 98.61 (a)
  • 98 (a)
(Rattus norvegicus)
Mammalia Mroh2b 35
  • 82.8 (n)
  • 81.63 (a)
(Monodelphis domestica)
Mammalia MROH2B 36
  • 61 (a)
(Ornithorhynchus anatinus)
Mammalia MROH2B 36
  • 58 (a)
(Gallus gallus)
Aves LOC101747491 35
  • 50.37 (n)
  • 44.44 (a)
-- 36
  • 20 (a)
-- 36
  • 19 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 30 (a)
fruit fly
(Drosophila melanogaster)
Insecta c11.1 36
  • 16 (a)
(Caenorhabditis elegans)
Secernentea hpo-27 36
  • 16 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 19 (a)
Species with no ortholog for MROH2B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • zebrafish (Danio rerio)

Evolution for MROH2B Gene

Gene Tree for MROH2B (if available)
Gene Tree for MROH2B (if available)

Paralogs for MROH2B Gene

Paralogs for MROH2B Gene

Selected SIMAP similar genes for MROH2B Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with MROH2B: view

Variants for MROH2B Gene

Sequence variations from dbSNP and Humsavar for MROH2B Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type MAF
rs167814 -- 41,040,928(+) CCAAA(A/G)TGCTG intron-variant
rs167815 -- 41,066,026(+) AACTT(C/G)GAGGT intron-variant
rs170529 -- 41,043,921(+) AAGAA(C/G)AACAG intron-variant
rs178985 -- 41,028,396(+) tatta(A/G)atctt intron-variant
rs182731 -- 41,028,045(+) gggtg(A/G)gggga intron-variant

Relevant External Links for MROH2B Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for MROH2B Gene

Disorders for MROH2B Gene

No disorders were found for MROH2B Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for MROH2B Gene

Publications for MROH2B Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. Use of a genetic isolate to identify rare disease variants: C7 on 5p associated with MS. (PMID: 19221116) Kallio S.P. … Saarela J. (Hum. Mol. Genet. 2009) 3
  4. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3
  5. A census of human soluble protein complexes. (PMID: 22939629) Havugimana P.C. … Emili A. (Cell 2012) 3

Products for MROH2B Gene

Sources for MROH2B Gene

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