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MRO Gene

protein-coding   GIFtS: 45
GCID: GC18M048321

Maestro

(Previous name: chromosome 18 open reading frame 3)
(Previous symbol: C18orf3)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
maestro1 2     B29 Protein1
C18orf31 2 3     Chromosome 18 Open Reading Frame 31
B292 3 5     Protein Maestro2
Beside The Ma29 Deletion1 2     Protein B293
Male-Specific Transcription In The Developing Reproductive Organs2 3     

External Ids:    HGNC: 241211   Entrez Gene: 838762   Ensembl: ENSG000001340427   OMIM: 6080805   UniProtKB: Q9BYG73   

Export aliases for MRO gene to outside databases

Previous GC identifers: GC18M046577 GC18M046578 GC18M045176


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for MRO Gene:
This gene is specifically transcribed in males before and after differentiation of testis, and the encoded protein
may play an important role in a mammalian sex determination. Multiple transcript variants encoding different
isoforms have been found for this gene. (provided by RefSeq, Jul 2008)

GeneCards Summary for MRO Gene:
MRO (maestro) is a protein-coding gene. Diseases associated with MRO include melorheostosis, and osteopoikilosis. An important paralog of this gene is MROH2A.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000018.10  NT_010966.15  NC_018929.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the MRO gene promoter:
         Oct-B1   TBP   oct-B2   oct-B3   POU2F1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMRO promoter sequence
   Search Chromatin IP Primers for MRO

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MRO


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 18q21   Ensembl cytogenetic band:  18q21.2   HGNC cytogenetic band: 18q21

MRO Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MRO gene location

GeneLoc information about chromosome 18         GeneLoc Exon Structure

GeneLoc location for GC18M048321:  view genomic region     (about GC identifiers)

Start:
48,321,490 bp from pter      End:
48,351,772 bp from pter
Size:
30,283 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: MSTRO_HUMAN, Q9BYG7 (See protein sequence)
Recommended Name: Protein maestro  
Size: 248 amino acids; 29054 Da
Secondary accessions: B7Z2I5 B7Z3B2 E9PAT5 E9PBI3 K7EKJ8 Q8N6K5
Alternative splicing: 6 isoforms:  Q9BYG7-1   Q9BYG7-2   Q9BYG7-3   Q9BYG7-4   Q9BYG7-5   Q9BYG7-6   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for MRO: NX_Q9BYG7

Explore proteomics data for MRO at MOPED


See MRO Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins (4 alternative transcripts): 
NP_001120646.1  NP_001120647.1  NP_001120648.1  NP_114145.2  

ENSEMBL proteins: 
 ENSP00000465783   ENSP00000409509   ENSP00000392614   ENSP00000256425   ENSP00000465653  
 ENSP00000397900   ENSP00000381465   ENSP00000467427   ENSP00000466218  

MRO Human Recombinant Protein Products:

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OriGene Protein Over-expression Lysate for MRO
OriGene Custom MassSpec
OriGene Custom Protein Services for MRO
GenScript Custom Purified and Recombinant Proteins Services for MRO
Novus Biologicals MRO Protein
Novus Biologicals MRO Lysate
Browse Sino Biological Recombinant Proteins
Browse Sino Biological Cell Lysates
Browse ProSpec Recombinant Proteins
Cloud-Clone Corp. Proteins for MRO

MRO Antibody Products:

Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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OriGene Custom Antibody Services for MRO
Novus Biologicals MRO Antibodies
Abcam antibodies for MRO
Cloud-Clone Corp. Antibodies for MRO
Search ThermoFisher Antibodies for MRO
LSBio Antibodies in human, mouse, rat for MRO

MRO Assay Products:

Browse Kits and Assays available from EMD Millipore
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Browse R&D Systems for biochemical assays
GenScript Custom Assay Services for MRO
Browse Enzo Life Sciences for kits & assays
Cloud-Clone Corp. ELISAs for MRO
Cloud-Clone Corp. CLIAs for MRO


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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HGNC Gene Families:
MROH: maestro heat-like repeat containing

2 InterPro protein domains:
 IPR011989 ARM-like
 IPR016024 ARM-type_fold

Graphical View of Domain Structure for InterPro Entry Q9BYG7

ProtoNet protein and cluster: Q9BYG7

1 Blocks protein domain: IPB000357 HEAT repeat

UniProtKB/Swiss-Prot: MSTRO_HUMAN, Q9BYG7
Similarity: Contains 1 HEAT repeat


MRO for domains           About GeneDecksing


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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     Gene Ontology (GO): 1 molecular function term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005488binding ----
     
MRO for ontologies           About GeneDecksing


Phenotypes:
     4 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Mro):
 behavior/neurological  growth/size/body  no phenotypic analysis  reproductive system 

MRO for phenotypes           About GeneDecksing

Animal Models:
   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for MRO
   inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for MRO

   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for MRO
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for MRO

miRNA
Products:
    
Block miRNA regulation of human, mouse, rat MRO using miScript Target Protectors
Selected qRT-PCR Assays for microRNAs that regulate MRO (see all 16):
hsa-miR-539 hsa-miR-548s hsa-miR-3150a-3p hsa-miR-4314 hsa-miR-1290 hsa-miR-3671 hsa-miR-595 hsa-miR-4268
SwitchGear 3'UTR luciferase reporter plasmidMRO 3' UTR sequence
Inhib. RNA
Products:
    
OriGene RNAi products in human, mouse, rat for MRO
Predesigned siRNA for gene silencing in human, mouse, rat MRO

Gene Editing
Products:
DNA2.0 Custom Protein Engineering Service for MRO

Clone
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OriGene clones in human, mouse for MRO (see all 22)
OriGene ORF clones in mouse, rat for MRO
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript Custom all cDNA clones Services for MRO
Browse Sino Biological Human cDNA Clones
DNA2.0 Custom Codon Optimized Gene Synthesis Service for MRO
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MRO

Cell Line
Products:
     
GenScript Custom overexpressing Cell Line Services for MRO
Browse ESI BIO Cell Lines and PureStem Progenitors for MRO 
In Situ Assay
Products:
   

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MRO


(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot
MSTRO_HUMAN, Q9BYG7: Nucleus, nucleolus (By similarity)
Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
cytosol2
nucleus2

Gene Ontology (GO): 2 cellular component terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005634nucleus ----
GO:0005730nucleolus IEA--

MRO for ontologies           About GeneDecksing


(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for MRO
Interactions:

    Search GeneGlobe Interaction Network for MRO

1 Interacting protein for MRO (Q9BYG73) via UniProtKB, MINT, STRING, and/or I2D
InteractantInteraction Details
GeneCardExternal ID(s)
OS9Q134383I2D: score=1 
About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for MRO (MSTRO)



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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REFSEQ mRNAs for MRO gene (4 alternative transcripts): 
NM_001127174.1  NM_001127175.1  NM_001127176.1  NM_031939.3  

Unigene Cluster for MRO:

Maestro
Hs.30495  [show with all ESTs]
Unigene Representative Sequence: NM_031939
10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000585524 ENST00000428869(uc010dpc.3) ENST00000431965(uc010dpb.3)
ENST00000256425 ENST00000588444 ENST00000436348(uc010dpa.3) ENST00000398439(uc010xdn.2 uc002lew.4 uc002lex.4)
ENST00000592966 ENST00000587291 ENST00000590988
miRNA
Products:
     
Block miRNA regulation of human, mouse, rat MRO using miScript Target Protectors
Selected qRT-PCR Assays for microRNAs that regulate MRO (see all 16):
hsa-miR-539 hsa-miR-548s hsa-miR-3150a-3p hsa-miR-4314 hsa-miR-1290 hsa-miR-3671 hsa-miR-595 hsa-miR-4268
SwitchGear 3'UTR luciferase reporter plasmidMRO 3' UTR sequence
Inhib. RNA
Products:
     
OriGene RNAi products in human, mouse, rat for MRO
Predesigned siRNA for gene silencing in human, mouse, rat MRO
Clone
Products:
     
OriGene clones in human, mouse for MRO (see all 22)
OriGene ORF clones in mouse, rat for MRO
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript Custom all cDNA clones Services for MRO
DNA2.0 Custom Codon Optimized Gene Synthesis Service for MRO
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MRO
Primer
Products:
    
OriGene qSTAR qPCR primer pairs in human, mouse for MRO
Pre-validated RT2 qPCR Primer Assay in human, mouse, rat MRO
  QuantiTect SYBR Green Assays in human, mouse, rat MRO
  QuantiFast Probe-based Assays in human, mouse, rat MRO

Additional mRNA sequence: 

AB042647.1 AK054702.1 AK294757.1 AK295666.1 BC029860.1 

6 DOTS entries:

DT.95222495  DT.100018021  DT.75100889  DT.100018022  DT.99997959  DT.121097458 

Selected AceView cDNA sequences (see all 25):

AI016513 BI829978 AI431829 BP348764 BF512298 CD673156 AI538185 AL705398 
AA884302 NM_031939 AI538175 AI829586 CD243973 BX114686 AW070224 AK054702 
AI568156 AB042647 BC029860 BE466301 AI827773 AW271651 BU854524 BF511412 

GeneLoc Exon Structure

5 Alternative Splicing Database (ASD) splice patterns (SP) for MRO    About this scheme

ExUns: 1a · 1b ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5a · 5b ^ 6a · 6b · 6c ^ 7 ^ 8a · 8b ^ 9a · 9b
SP1:                          -                                                                           
SP2:              -     -     -     -                                         -                           
SP3:              -     -     -                                                                           
SP4:                          -     -           -                             -                           
SP5:                                                                                                      


ECgene alternative splicing isoforms for MRO

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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MRO expression in normal human tissues (normalized intensities)      MRO embryonic expression: see
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: AGTGTAAGTG
MRO Expression
About this image


MRO expression in embryonic tissues and stem cells    About this table
Data from LifeMap, the Embryonic Development and Stem Cells Database
 selected tissues (see all 4) fully expand
 
 Ovary (Reproductive System)    fully expand to see all 2 entries
         Granulosa Cells Primary Follicle
         Mature follicles
 
 Testis (Reproductive System)
         Pre-Sertoli Cells Testis Cord
 
 Brain (Nervous System)
         Adult Oligodendrocyte Precursor Cells Lateral Ventricle
 
 Kidney (Urinary System)
MRO Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

MRO Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.30495

UniProtKB/Swiss-Prot: MSTRO_HUMAN, Q9BYG7
Tissue specificity: Ubiquitous

    Custom PCR Arrays for MRO
Primer
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OriGene qSTAR qPCR primer pairs in human, mouse for MRO
Pre-validated RT2 qPCR Primer Assay in human, mouse, rat MRO
QuantiTect SYBR Green Assays in human, mouse, rat MRO
QuantiFast Probe-based Assays in human, mouse, rat MRO
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MRO

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of animals.

Orthologs for MRO gene from Selected species (see all 12)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Mro1 , 5 maestro1, 5 79.23(n)1
74.18(a)1
  18 (50.21 cM)5
712631  NM_027741.21  NP_082017.21 
 738593855 
chicken
(Gallus gallus)
Aves --
--
(see all 14)
Uncharacterized protein
(see all 14)


(see all 14)
many ↔ many
many ↔ many
(see all 14)
1(121027874-121033370)
1(122103149-122107413)
lizard
(Anolis carolinensis)
Reptilia --
--
5(a)
1 → many
GL343501.1(41664-122234)
fruit fly
(Drosophila melanogaster)
Insecta c11.16
c11.1
3(a)
1 → many
X(9169681-9177150)
worm
(Caenorhabditis elegans)
Secernentea hpo-276
Protein HPO-27 (hpo-27) mRNA, complete cds
2(a)
1 → many
I(5906662-5918229) WBGene00016418


ENSEMBL Gene Tree for MRO (if available)
TreeFam Gene Tree for MRO (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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Paralogs for MRO gene
MROH2A2  MROH2B2  MROH82  MROH7-TTC42  MROH62  MROH72  MROH12  
2 SIMAP similar genes for MRO using alignment to 4 protein entries:     MSTRO_HUMAN (see all proteins):
MROH2B    MROH2A

MRO for paralogs           About GeneDecksing



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for MRO (see all 887)    About this table    
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 18 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs28475411,2
C,F,H--48321014(-) AATTGC/TTGGGC 4 -- ds500122Minor allele frequency- T:0.24NS EA NA 2646
rs72326701,2
C,F,H--48321026(+) tatacA/Cttggg 4 -- ds50015Minor allele frequency- C:0.03NS EA WA 538
rs1868020351,2
--48321100(+) CTAAAC/TGGCAG 4 -- ds50010--------
rs1429450311,2
--48321158(+) GGGCAC/TTTGGA 4 -- ds50010--------
rs1912744961,2
--48321176(+) CAGGGA/CATGGC 4 -- ds50010--------
rs1511157041,2
--48321225(+) GGAATC/TGAGGA 4 -- ds50010--------
rs1840979751,2
--48321245(+) GGAAAC/TTCTAG 4 -- ds50010--------
rs1410521621,2
--48321410(+) TGAAAC/TCATTT 4 -- ds50010--------
rs1450146411,2
C--48321415(+) CCATTC/TAACAT 4 -- ds50010--------
rs1897855281,2
--48321419(+) TTAACA/GTGTAA 4 -- ds50010--------

HapMap Linkage Disequilibrium report for MRO (48321490 - 48351772 bp)

Structural Variations
     Database of Genomic Variants (DGV) 2 variations for MRO:    About this table    
Variant IDTypeSubtypePubMed ID
nsv9630CNV Loss18304495
nsv527714CNV Gain19592680

Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing MRO
DNA2.0 Custom Variant and Variant Library Synthesis for MRO

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 608080    OMIM disorders: --

2 diseases for MRO:    About MalaCards
melorheostosis    osteopoikilosis

2 diseases from the University of Copenhagen DISEASES database for MRO:
Melorheostosis     Osteopoikilosis

MRO for disorders           About GeneDecksing


Export disorders for MRO gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for MRO gene integrated from 10 sources:
(articles sorted by number of sources associating them with MRO)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Physical and transcriptional map of a 311-kb segment of chromosome 18q21, a candidate lung tumor suppressor locus. (PubMed id 11401430)1, 2, 3 Yanaihara N.... Yokota J. (Genomics 2001)
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
  4. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (Genomics 2007)
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
  6. DNA sequence and analysis of human chromosome 18. (PubMed id 16177791)2 Nusbaum C.... Lander E.S. (Nature 2005)
  7. Candidate testis-determining gene, Maestro (Mro), encodes a novel HEAT repeat protein. (PubMed id 12889070)1 Smith L....Greenfield A. (Dev. Dyn. 2003)
  8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

(in PubMed, OMIM, and NCBI Bookshelf)
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 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 83876 HGNC: 24121 AceView: MRO Ensembl:ENSG00000134042 euGenes: HUgn83876
ECgene: MRO H-InvDB: MRO

(According to HUGE)
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  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for MRO Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for MRO gene:
Search GeneIP for patents involving MRO

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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 Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for MRO  
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 Block miRNA regulation of human, mouse, rat MRO using miScript Target Protectors SeqTarget long-range PCR primers for resequencing MRO
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 Search Tocris compounds for MRO (MSTRO)
 Browse Sino Biological Proteins
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 Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

 Novus Tissue Slides
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 See all of Abcam's Antibodies, Kits and Proteins for MRO
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 Browse ESI BIO Cell Lines and PureStem Progenitors for MRO
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 SwitchGear 3'UTR luciferase reporter plasmids for MRO
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 Search ThermoFisher Antibodies for MRO
 Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MRO
 inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for MRO
 inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for MRO
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Customized transgenic rodents for:
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GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

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