Aliases for MRI1 Gene
External Ids for MRI1 Gene
Previous GeneCards Identifiers for MRI1 Gene
GeneCards Summary for MRI1 Gene
MRI1 (Methylthioribose-1-Phosphate Isomerase 1) is a Protein Coding gene. Diseases associated with MRI1 include Spinal Cord Melanoma and Visual Agnosia. Among its related pathways are Sulfur amino acid metabolism and CDK-mediated phosphorylation and removal of Cdc6. GO annotations related to this gene include identical protein binding and S-methyl-5-thioribose-1-phosphate isomerase activity.
UniProtKB/Swiss-Prot for MRI1 Gene
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Independently from catalytic activity, promotes cell invasion in response to constitutive RhoA activation by promoting FAK tyrosine phosphorylation and stress fiber turnover.