Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MRGPRG Gene

Aliases for MRGPRG Gene

  • MAS-Related GPR, Member G 2 3
  • MRGG 3 4 6
  • G Protein-Coupled Receptor 169 2 3
  • GPR169 3 4
  • Mas-Related G-Protein Coupled Receptor Member G 3
  • G Protein-Coupled Receptor MRGG 3
  • G-Protein Coupled Receptor 169 4

External Ids for MRGPRG Gene

Previous Symbols for MRGPRG Gene

  • GPR169

Summaries for MRGPRG Gene

GeneCards Summary for MRGPRG Gene

MRGPRG (MAS-Related GPR, Member G) is a Protein Coding gene. GO annotations related to this gene include G-protein coupled receptor activity. An important paralog of this gene is MRGPRX4.

UniProtKB/Swiss-Prot for MRGPRG Gene

  • Orphan receptor. May regulate nociceptor function and/or development, including the sensation or modulation of pain (By similarity).

Gene Wiki entry for MRGPRG Gene

No data available for Entrez Gene Summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MRGPRG Gene

Genomics for MRGPRG Gene

Genomic Location for MRGPRG Gene

Start:
3,217,944 bp from pter
End:
3,218,813 bp from pter
Size:
870 bases
Orientation:
Minus strand

Genomic View for MRGPRG Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MRGPRG Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MRGPRG Gene

Regulatory Elements for MRGPRG Gene

Proteins for MRGPRG Gene

  • Protein details for MRGPRG Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q86SM5-MRGRG_HUMAN
    Recommended name:
    Mas-related G-protein coupled receptor member G
    Protein Accession:
    Q86SM5
    Secondary Accessions:

    Protein attributes for MRGPRG Gene

    Size:
    289 amino acids
    Molecular mass:
    31518 Da
    Quaternary structure:
    No Data Available

neXtProt entry for MRGPRG Gene

Proteomics data for MRGPRG Gene at MOPED

Post-translational modifications for MRGPRG Gene

No Post-translational modifications

Other Protein References for MRGPRG Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for MRGPRG Gene

Domains for MRGPRG Gene

Gene Families for MRGPRG Gene

HGNC:
  • GPCRAO :GPCR / Class A : Orphans
IUPHAR :

Protein Domains for MRGPRG Gene

UniProtKB/Swiss-Prot:

MRGRG_HUMAN
Family:
  • Belongs to the G-protein coupled receptor 1 family. Mas subfamily.:
    • Q86SM5
genes like me logo Genes that share domains with MRGPRG: view

Function for MRGPRG Gene

Molecular function for MRGPRG Gene

UniProtKB/Swiss-Prot Function: Orphan receptor. May regulate nociceptor function and/or development, including the sensation or modulation of pain (By similarity).

Gene Ontology (GO) - Molecular Function for MRGPRG Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
genes like me logo Genes that share ontologies with MRGPRG: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MRGPRG Gene

Localization for MRGPRG Gene

Subcellular locations from UniProtKB/Swiss-Prot for MRGPRG Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for MRGPRG Gene COMPARTMENTS Subcellular localization image for MRGPRG gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for MRGPRG Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with MRGPRG: view

Pathways for MRGPRG Gene

SuperPathways for MRGPRG Gene

No Data Available

Interacting Proteins for MRGPRG Gene

Gene Ontology (GO) - Biological Process for MRGPRG Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IEA --
genes like me logo Genes that share ontologies with MRGPRG: view

No data available for Pathways by source for MRGPRG Gene

Transcripts for MRGPRG Gene

mRNA/cDNA for MRGPRG Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MRGPRG Gene

No ASD Table

Relevant External Links for MRGPRG Gene

GeneLoc Exon Structure for
MRGPRG
ECgene alternative splicing isoforms for
MRGPRG

Expression for MRGPRG Gene

mRNA expression in normal human tissues for MRGPRG Gene

mRNA differential expression in normal tissues according to GTEx for MRGPRG Gene

This gene is overexpressed in Testis (42.9) and Cervix - Endocervix (5.1).

SOURCE GeneReport for Unigene cluster for MRGPRG Gene Hs.730306

genes like me logo Genes that share expressions with MRGPRG: view

Orthologs for MRGPRG Gene

This gene was present in the common ancestor of chordates.

Orthologs for MRGPRG Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia MRGPRG 36
  • 98.15 (n)
  • 96.87 (a)
MRGPRG 37
  • 97 (a)
OneToOne
cow
(Bos Taurus)
Mammalia LOC618771 36
  • 77.82 (n)
  • 66.55 (a)
MRGPRG 37
  • 66 (a)
OneToOne
dog
(Canis familiaris)
Mammalia MRGPRG 36
  • 78.55 (n)
  • 67.48 (a)
MRGPRG 37
  • 67 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mrgprg 36
  • 69.36 (n)
  • 57.89 (a)
Mrgprg 16
Mrgprg 37
  • 57 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 37
  • 36 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 37
  • 30 (a)
ManyToMany
-- 37
  • 32 (a)
ManyToMany
-- 37
  • 32 (a)
ManyToMany
rat
(Rattus norvegicus)
Mammalia Mrgprg 36
  • 69.11 (n)
  • 57.69 (a)
chicken
(Gallus gallus)
Aves -- 37
  • 21 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 37
  • 22 (a)
ManyToMany
-- 37
  • 23 (a)
ManyToMany
-- 37
  • 27 (a)
ManyToMany
-- 37
  • 24 (a)
ManyToMany
-- 37
  • 23 (a)
ManyToMany
-- 37
  • 25 (a)
ManyToMany
-- 37
  • 25 (a)
ManyToMany
-- 37
  • 27 (a)
ManyToMany
-- 37
  • 25 (a)
ManyToMany
-- 37
  • 17 (a)
ManyToMany
-- 37
  • 21 (a)
ManyToMany
-- 37
  • 21 (a)
ManyToMany
-- 37
  • 22 (a)
ManyToMany
-- 37
  • 19 (a)
ManyToMany
-- 37
  • 22 (a)
ManyToMany
-- 37
  • 22 (a)
ManyToMany
Species with no ortholog for MRGPRG:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MRGPRG Gene

ENSEMBL:
Gene Tree for MRGPRG (if available)
TreeFam:
Gene Tree for MRGPRG (if available)

Paralogs for MRGPRG Gene

Paralogs for MRGPRG Gene

Selected SIMAP similar genes for MRGPRG Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with MRGPRG: view

Variants for MRGPRG Gene

Structural Variations from Database of Genomic Variants (DGV) for MRGPRG Gene

Variant ID Type Subtype PubMed ID
nsv469931 CNV Loss 18288195
dgv1015n71 CNV Loss 21882294
nsv7649 CNV Loss 18451855
nsv524468 CNV Loss 19592680
dgv334e1 CNV Complex 17122850
dgv335e1 CNV Complex 17122850
nsv428245 CNV Gain 18775914
dgv336e1 CNV Complex 17122850
esv27427 CNV Loss 19812545
esv992308 CNV Deletion 20482838
dgv19e180 CNV Loss 20482838
esv2744033 CNV Deletion 23290073
esv2678047 CNV Deletion 23128226

Relevant External Links for MRGPRG Gene

HapMap Linkage Disequilibrium report
MRGPRG

No data available for Sequence variations from dbSNP and Humsavar for MRGPRG Gene

Disorders for MRGPRG Gene

No disorders were found for MRGPRG Gene.

No data available for UniProtKB/Swiss-Prot for MRGPRG Gene

Publications for MRGPRG Gene

  1. The G protein-coupled receptor repertoires of human and mouse. (PMID: 12679517) Vassilatis D.K. … Gaitanaris G.A. (Proc. Natl. Acad. Sci. U.S.A. 2003) 2 3 4
  2. The DNA sequence and comparative analysis of human chromosome 10. (PMID: 15164054) Deloukas P. … Rogers J. (Nature 2004) 3 4

Products for MRGPRG Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • Pathway & Disease-focused RT² Profiler PCR Arrays
  • QIAGEN qRT-PCR Assays for microRNAs that regulate MRGPRG
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for MRGPRG
    • Block miRNA regulation of MRGPRG using miScript Target Protectors

    Sources for MRGPRG Gene

    Back to Top

    Content